Click here to switch to the map view.

The map label for this gene is apbE [H]

Identifier: 94314556

GI number: 94314556

Start: 2397261

End: 2398274

Strand: Reverse

Name: apbE [H]

Synonym: Rmet_5637

Alternate gene names: 94314556

Gene position: 2398274-2397261 (Counterclockwise)

Preceding gene: 94314557

Following gene: 94314555

Centisome position: 92.95

GC content: 68.93

Gene sequence:

>1014_bases
ATGAATCGCGTTCTTATCCCCGCCACGCTGGACCTGCCCCCGCCCGTTCGCGAGCCGCAAGGCTCGATCGCGCAATGGAC
GGGCGAGACGATGGGGACGACCTGGGCTGTCCGCGCCGTGCTGGCGCGCGGGCAGGACGGCGGCGGCCTGGAGGCAGGCA
TCCGCGCGGTGCTCGACGAGGTTATCGCGCAGATGAGCAACTGGTCCGAGATATCGGACCTGAGCCGTTTCAATCGGGCC
GACGCCAGTGCTTGGGTCACGCTGCCCGAGGATTGCTTCACGGTCCTGCAGGCGGCGCTGGACACCGCGCGCGACAGCGG
TGGCGCCTACGATCCCAGTGCCGGCCCGCTCGTCGATCTCTGGGGCTTCGGCCCGGCTGGCAAACGGCACACCGCGCCTA
CCGCCGATGACGTGGCACGGGCGCGCCAGCATTGCGGCTGGCAACGGATCGAGATCGACCCATCGGCGCGTCGCGCGCGC
CAGCCGGGCGGACTGTCACTCGATTTCTGCGCGATCGCGAAGGGGTTTGCCGTCGATGCGGTATCGCGCTATCTCCTGGC
CCAGGGCGTGCCGCATCATCTGGTCGAGATCGGCGGCGAGTTGCGCGGCCAGGGGCTGAAGCCCGATGGGATGCCGTGGT
GGATCGAACTGGAGTCCCCCTCGGCATCTGCCACTGCTGCGGGCGGGATCAGACGTACGCTGGTGGCGTTGCTCGGCCTG
TCGATCGCCACGTCGGGCGACTACCGCCGCTACTTCGAACACGATGGGCGGCGGTACGCGCATACGATTGATCCACGCAC
CGGCTACCCGGCCGCGCATGCGTTGGCGTCCGTCACGGTGCTCCATCGCGAATGCATGATGGCCGACGCGTTGTCCACCG
CACTGACCGTGCTCGGGCCAGAAGCCGGCATCACCTTCGCCACGCGCCAGGGCCTGGCTGCCCGCTTCCTGGTGCGCACG
CCGCACGGCTTCGATGAGCGGGTCACCCCGGCGTTCGCCGCGATGCAAACATGA

Upstream 100 bases:

>100_bases
GACCAGAAGACATCGGTCAAGCCCGCCACGGCTCGCCGCGTTACCTACGCGGTGACGGTGGAAGTGCTGCCGCAGTAAGA
CGGCCGCTACGAAATCGCCG

Downstream 100 bases:

>100_bases
TGCGTCTTCTACCGTGGGCAATGCTTGTCGCCGGTGTGGCGCTGTCCGTGCTCGCGCACGGTCGCGATGCCATGGCAGCC
GGCGTGGTCATCGCGTACGT

Product: ApbE-like lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MNRVLIPATLDLPPPVREPQGSIAQWTGETMGTTWAVRAVLARGQDGGGLEAGIRAVLDEVIAQMSNWSEISDLSRFNRA
DASAWVTLPEDCFTVLQAALDTARDSGGAYDPSAGPLVDLWGFGPAGKRHTAPTADDVARARQHCGWQRIEIDPSARRAR
QPGGLSLDFCAIAKGFAVDAVSRYLLAQGVPHHLVEIGGELRGQGLKPDGMPWWIELESPSASATAAGGIRRTLVALLGL
SIATSGDYRRYFEHDGRRYAHTIDPRTGYPAAHALASVTVLHRECMMADALSTALTVLGPEAGITFATRQGLAARFLVRT
PHGFDERVTPAFAAMQT

Sequences:

>Translated_337_residues
MNRVLIPATLDLPPPVREPQGSIAQWTGETMGTTWAVRAVLARGQDGGGLEAGIRAVLDEVIAQMSNWSEISDLSRFNRA
DASAWVTLPEDCFTVLQAALDTARDSGGAYDPSAGPLVDLWGFGPAGKRHTAPTADDVARARQHCGWQRIEIDPSARRAR
QPGGLSLDFCAIAKGFAVDAVSRYLLAQGVPHHLVEIGGELRGQGLKPDGMPWWIELESPSASATAAGGIRRTLVALLGL
SIATSGDYRRYFEHDGRRYAHTIDPRTGYPAAHALASVTVLHRECMMADALSTALTVLGPEAGITFATRQGLAARFLVRT
PHGFDERVTPAFAAMQT
>Mature_337_residues
MNRVLIPATLDLPPPVREPQGSIAQWTGETMGTTWAVRAVLARGQDGGGLEAGIRAVLDEVIAQMSNWSEISDLSRFNRA
DASAWVTLPEDCFTVLQAALDTARDSGGAYDPSAGPLVDLWGFGPAGKRHTAPTADDVARARQHCGWQRIEIDPSARRAR
QPGGLSLDFCAIAKGFAVDAVSRYLLAQGVPHHLVEIGGELRGQGLKPDGMPWWIELESPSASATAAGGIRRTLVALLGL
SIATSGDYRRYFEHDGRRYAHTIDPRTGYPAAHALASVTVLHRECMMADALSTALTVLGPEAGITFATRQGLAARFLVRT
PHGFDERVTPAFAAMQT

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=326, Percent_Identity=30.6748466257669, Blast_Score=174, Evalue=8e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 36101; Mature: 36101

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRVLIPATLDLPPPVREPQGSIAQWTGETMGTTWAVRAVLARGQDGGGLEAGIRAVLDE
CCCEEEEEECCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHH
VIAQMSNWSEISDLSRFNRADASAWVTLPEDCFTVLQAALDTARDSGGAYDPSAGPLVDL
HHHHHCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEE
WGFGPAGKRHTAPTADDVARARQHCGWQRIEIDPSARRARQPGGLSLDFCAIAKGFAVDA
CCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHCCCCCCEEHHHHHHCCHHHHH
VSRYLLAQGVPHHLVEIGGELRGQGLKPDGMPWWIELESPSASATAAGGIRRTLVALLGL
HHHHHHHCCCHHHHHHHCHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
SIATSGDYRRYFEHDGRRYAHTIDPRTGYPAAHALASVTVLHRECMMADALSTALTVLGP
HHHCCCCHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EAGITFATRQGLAARFLVRTPHGFDERVTPAFAAMQT
CCCEEHHHHCCCHHEEEEECCCCCCCCCCHHHHHHCC
>Mature Secondary Structure
MNRVLIPATLDLPPPVREPQGSIAQWTGETMGTTWAVRAVLARGQDGGGLEAGIRAVLDE
CCCEEEEEECCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHH
VIAQMSNWSEISDLSRFNRADASAWVTLPEDCFTVLQAALDTARDSGGAYDPSAGPLVDL
HHHHHCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEE
WGFGPAGKRHTAPTADDVARARQHCGWQRIEIDPSARRARQPGGLSLDFCAIAKGFAVDA
CCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHCCCCCCEEHHHHHHCCHHHHH
VSRYLLAQGVPHHLVEIGGELRGQGLKPDGMPWWIELESPSASATAAGGIRRTLVALLGL
HHHHHHHCCCHHHHHHHCHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
SIATSGDYRRYFEHDGRRYAHTIDPRTGYPAAHALASVTVLHRECMMADALSTALTVLGP
HHHCCCCHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EAGITFATRQGLAARFLVRTPHGFDERVTPAFAAMQT
CCCEEHHHHCCCHHEEEEECCCCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]