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The map label for this gene is lysN [H]

Identifier: 94314495

GI number: 94314495

Start: 2330104

End: 2331327

Strand: Direct

Name: lysN [H]

Synonym: Rmet_5576

Alternate gene names: 94314495

Gene position: 2330104-2331327 (Clockwise)

Preceding gene: 94314494

Following gene: 94314497

Centisome position: 90.31

GC content: 69.04

Gene sequence:

>1224_bases
ATGGCCGCCTACCCCTTCGTTCCCGCGCTACGCGAGCCGCAAGGCTCGCCGATCCGCGAGCTGTTCAAGTATCTCTCCGA
CCCGGAGATGATCTCGTTCGCCGGCGGCTATCCGTCCGCCGCGTTGTTCGACGTGGAAGGCATCGGCGCGGCATCCGCAC
AGGCATTGCGCGAACGTCCTGCCGAGTGCCTGCAGTACGGCGCCACGGAGGGCACGCCTGCGCTGCGCAACGCGCTGGCG
GCCCTGATGGCGGAGCGTGGCGCGGCCGTCGCCCTGGACGAACTGCTGATCACCAGCGGCTCGCAACAGGGCTTCGATTT
TCTCGTGCGCGCGCTGGTGGAGCCTGGCAGCCTCGTGCTGGTGGAGGAACCCACCTACTCGGCCACGCTGCAGGCACTGC
GGCTGGCCGGCGCTGACGTGCGCGGCGTGCCGTCCGACCATGACGGCATGAACGTCGACGCACTGGAGGCGATGCTCGCA
GACGCGCCGGCACGTCCTCGCATGATCTACACGGTGCCGACCTTCGCCAATCCAACCGGCGCCACGCTCTCACCCGCGCG
CCGGCTTCAATTGCTGGAACTGGTGGCACGGCACGAGATCGTGCTGGTCGAGGACGATCCTTACGGCGCGCTAAGCTTCG
ACGGTCCGCCGCCGCCATCGCTGCTCGCGCTGTGCGATCAGGTGTCCGGCGCGCGCCCGTGGCTCGTGCATCTCGCAAGC
CTGTCGAAGACGCTGGCACCAGGACTGCGGCTGGGCTGGATGGTGGCCGCGCCGGAGATCGTGCGTCGCGCGGTGATCGC
CAAGCAGGTGTCGGACCTGTGCACGCCGCCATGGCTGCAACTGACCGCCGCGCATTACCTTCAGGCCGGAAACCTGCCCG
GGCAGATCGCGCGGGAAGTGGCGGTCTATCGCGACAAACGCGATCGGCTGACGACGGCGTTGCACCAGGCGTTCGGCACG
CGCATCCGGTTTGCGGATCCCGCCGGGGGCATGTTCCTGTGGGTATCCGTGGACGGCATCGACGATGCGGCGGCGCTGCT
GCCCCATGCCATCGCAGAGAAAGTGCTGTTCGTGCCGGGCACAGGCTTCTACGCCGAGCGTCGCGCGCGCCCCGCGTTCC
GGCTGTCGTTCGTGGGCGCCGACCCGGCGCAGATCGAAGAAGGCGTGGCGCGGCTTGCCCGGGCCGCAGCGCGTGCCGGG
GTATCCGTCGTCAATCCGGACTAA

Upstream 100 bases:

>100_bases
CGCGCACGGACCTGGGCTTCGACGCCGGCAATGCGCAGGGCATCTTCAAGATGACCGCGGCGGCCTGCTGAAGCGCGACG
TCCGCAACCACGAGCACGCC

Downstream 100 bases:

>100_bases
GCCAGGCGCTCAGACATCCAGCGTGCCGACGAAGCCGAACTCGACCGGCGTCTTCGCATAGAACAGGCGGATGTCTTCGT
GACGCAGGCGCTCCAGCAGC

Product: putative 2-aminoadipate transaminase

Products: NA

Alternate protein names: 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT [H]

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MAAYPFVPALREPQGSPIRELFKYLSDPEMISFAGGYPSAALFDVEGIGAASAQALRERPAECLQYGATEGTPALRNALA
ALMAERGAAVALDELLITSGSQQGFDFLVRALVEPGSLVLVEEPTYSATLQALRLAGADVRGVPSDHDGMNVDALEAMLA
DAPARPRMIYTVPTFANPTGATLSPARRLQLLELVARHEIVLVEDDPYGALSFDGPPPPSLLALCDQVSGARPWLVHLAS
LSKTLAPGLRLGWMVAAPEIVRRAVIAKQVSDLCTPPWLQLTAAHYLQAGNLPGQIAREVAVYRDKRDRLTTALHQAFGT
RIRFADPAGGMFLWVSVDGIDDAAALLPHAIAEKVLFVPGTGFYAERRARPAFRLSFVGADPAQIEEGVARLARAAARAG
VSVVNPD

Sequences:

>Translated_407_residues
MAAYPFVPALREPQGSPIRELFKYLSDPEMISFAGGYPSAALFDVEGIGAASAQALRERPAECLQYGATEGTPALRNALA
ALMAERGAAVALDELLITSGSQQGFDFLVRALVEPGSLVLVEEPTYSATLQALRLAGADVRGVPSDHDGMNVDALEAMLA
DAPARPRMIYTVPTFANPTGATLSPARRLQLLELVARHEIVLVEDDPYGALSFDGPPPPSLLALCDQVSGARPWLVHLAS
LSKTLAPGLRLGWMVAAPEIVRRAVIAKQVSDLCTPPWLQLTAAHYLQAGNLPGQIAREVAVYRDKRDRLTTALHQAFGT
RIRFADPAGGMFLWVSVDGIDDAAALLPHAIAEKVLFVPGTGFYAERRARPAFRLSFVGADPAQIEEGVARLARAAARAG
VSVVNPD
>Mature_406_residues
AAYPFVPALREPQGSPIRELFKYLSDPEMISFAGGYPSAALFDVEGIGAASAQALRERPAECLQYGATEGTPALRNALAA
LMAERGAAVALDELLITSGSQQGFDFLVRALVEPGSLVLVEEPTYSATLQALRLAGADVRGVPSDHDGMNVDALEAMLAD
APARPRMIYTVPTFANPTGATLSPARRLQLLELVARHEIVLVEDDPYGALSFDGPPPPSLLALCDQVSGARPWLVHLASL
SKTLAPGLRLGWMVAAPEIVRRAVIAKQVSDLCTPPWLQLTAAHYLQAGNLPGQIAREVAVYRDKRDRLTTALHQAFGTR
IRFADPAGGMFLWVSVDGIDDAAALLPHAIAEKVLFVPGTGFYAERRARPAFRLSFVGADPAQIEEGVARLARAAARAGV
SVVNPD

Specific function: Catalyzes the transfer of an amino group between 2- oxoadipate (2-OA) and glutamate (Glu) to yield alpha-aminodipate (AAA). It can also transaminate glutamate, leucine, and aromatic amino acids. It also conbtributes in the biosynthesis of other amino acid

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=415, Percent_Identity=31.3253012048193, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI33469970, Length=415, Percent_Identity=31.3253012048193, Blast_Score=186, Evalue=4e-47,
Organism=Escherichia coli, GI1790797, Length=406, Percent_Identity=26.3546798029557, Blast_Score=148, Evalue=8e-37,
Organism=Escherichia coli, GI1787710, Length=398, Percent_Identity=27.3869346733668, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1788722, Length=350, Percent_Identity=29.1428571428571, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786816, Length=397, Percent_Identity=25.9445843828715, Blast_Score=65, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6321236, Length=486, Percent_Identity=24.0740740740741, Blast_Score=106, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6321929, Length=422, Percent_Identity=22.5118483412322, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6321000, Length=426, Percent_Identity=23.943661971831, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21356535, Length=411, Percent_Identity=23.8442822384428, Blast_Score=126, Evalue=3e-29,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.39 [H]

Molecular weight: Translated: 43372; Mature: 43241

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAYPFVPALREPQGSPIRELFKYLSDPEMISFAGGYPSAALFDVEGIGAASAQALRERP
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCEEEECCCCCHHHHHHHHHCH
AECLQYGATEGTPALRNALAALMAERGAAVALDELLITSGSQQGFDFLVRALVEPGSLVL
HHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEE
VEEPTYSATLQALRLAGADVRGVPSDHDGMNVDALEAMLADAPARPRMIYTVPTFANPTG
EECCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCC
ATLSPARRLQLLELVARHEIVLVEDDPYGALSFDGPPPPSLLALCDQVSGARPWLVHLAS
CCCCHHHHHHHHHHHHHCCEEEEECCCCCEEECCCCCCHHHHHHHHHCCCCCHHHHHHHH
LSKTLAPGLRLGWMVAAPEIVRRAVIAKQVSDLCTPPWLQLTAAHYLQAGNLPGQIAREV
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHH
AVYRDKRDRLTTALHQAFGTRIRFADPAGGMFLWVSVDGIDDAAALLPHAIAEKVLFVPG
HHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHCEEEECC
TGFYAERRARPAFRLSFVGADPAQIEEGVARLARAAARAGVSVVNPD
CCHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEECCC
>Mature Secondary Structure 
AAYPFVPALREPQGSPIRELFKYLSDPEMISFAGGYPSAALFDVEGIGAASAQALRERP
CCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCEEEECCCCCHHHHHHHHHCH
AECLQYGATEGTPALRNALAALMAERGAAVALDELLITSGSQQGFDFLVRALVEPGSLVL
HHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEE
VEEPTYSATLQALRLAGADVRGVPSDHDGMNVDALEAMLADAPARPRMIYTVPTFANPTG
EECCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCC
ATLSPARRLQLLELVARHEIVLVEDDPYGALSFDGPPPPSLLALCDQVSGARPWLVHLAS
CCCCHHHHHHHHHHHHHCCEEEEECCCCCEEECCCCCCHHHHHHHHHCCCCCHHHHHHHH
LSKTLAPGLRLGWMVAAPEIVRRAVIAKQVSDLCTPPWLQLTAAHYLQAGNLPGQIAREV
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHH
AVYRDKRDRLTTALHQAFGTRIRFADPAGGMFLWVSVDGIDDAAALLPHAIAEKVLFVPG
HHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHCEEEECC
TGFYAERRARPAFRLSFVGADPAQIEEGVARLARAAARAGVSVVNPD
CCHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA