Click here to switch to the map view.

The map label for this gene is mmgC [H]

Identifier: 94314426

GI number: 94314426

Start: 2250813

End: 2251970

Strand: Reverse

Name: mmgC [H]

Synonym: Rmet_5507

Alternate gene names: 94314426

Gene position: 2251970-2250813 (Counterclockwise)

Preceding gene: 94314427

Following gene: 94314425

Centisome position: 87.28

GC content: 55.09

Gene sequence:

>1158_bases
ATGCAGAACGCACCATGGATGAATCCCGAGCTGGAGACTCTGCGCGACAGCGCAAGGCGATTCTACGAGGCGGAACTTCT
TCCGCATGAAGAGCGGTGGGCCCAACAGCAATGTGTTGACCGGGACGTTTGGTACAAGGCAGCGGAGGCCGGCCTTCTTT
GCGTCGGCATTCCCGAAGAGTACGGCGGCGGGGGAGGTAACTTCCTGCATGAGGCCGTCATCTTCGCTGAGCAAGGTCGC
ATGCTATGCCCTGGGCTGGGCAATTCACTCCATAGTGGAATCGTCGCACATTACATCCACAACTTCGCTTCTGAGCAGCA
AAAGCAGGAGTGGTTGCCGAAGATGGCCAAGGGAGAGTTAGTCGGAGGGCTTGCCATTACTGAGCCCGGCGCGGGGTCTG
ACGTGCAGAGCATTCGTACGGCGGCTCGGAAGGAGGGCGGTGATTACGTCATCAACGGCGCGAAGACCTACATCACTAAC
GGCAGCACAGCAAACCTCATTTGCGTCGTAGTTAAGACGGATCCTAACTTGGGAGCGAAGGGCATTTCGATCATCGTTGT
CGAAACAGACAAGGTAGAGGGTTTCCGGCGCGGACGAACCCTATCGAAAGTGGGACTTCATTCGCAGGACACAGCAGAGC
TGTTTTTTGACGATGTGAGAGTTCCCCAAGCCAACCTTCTCGGCAACGTAGAAGGACAAGGATTCAAGCAACTCATGAAA
GAGTTGAGTCGAGAACGCGTGATTACCGCCTTCATGTCGATGGCATGTATGGAGCGAGCCATCGAAGAGACCTTGAAATT
TGCTGCGGACAGAAAAGTATTCGGTCAGACCTTGCTGTCCATGCAGAATACGCGGTTCAAACTAGCCGAGTGTGAAACGA
AGTTGACGCTCGCGAAGGCGATGCTCAGCCATTGCAGTGCCAGTCTCCTGGAAGGCCAACTGAGCAGCGAGATAGCGGCC
ATGGCCAAGTGGTGGATCACCGATGCTTGCGGCCAGGTCGTCGACGAGTGCGTGCAGCTCCACGGTGGAGCAGGATTCAT
GCTCGAGTATCCGATTGCTCGGCTGTATCAAAACGTGAGAATCCACCGCATCCTTGCAGGGACCAACGAGATTATGAAGG
AAGTGATAGCCCGAGAGCTTGAAAAAAGAGCTGTCTAG

Upstream 100 bases:

>100_bases
GATTGCTACGGTCGCCGACAGGGAAGATTGATTGGCGCAGGATGCAGGAGCGCGCCAACATGCCAGAAGAACGGGCTAGC
TGAGAAGACAAGGAACAACC

Downstream 100 bases:

>100_bases
CCCAGCATGGGGGACGAAGTCCCCTGGTCTGATGAAAGGTTTTGTCAGGAGGGAGACAACTATGGCGACTGAAAAGACTA
GTACGAGTTCCTCGGAACAT

Product: Long-chain-acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MQNAPWMNPELETLRDSARRFYEAELLPHEERWAQQQCVDRDVWYKAAEAGLLCVGIPEEYGGGGGNFLHEAVIFAEQGR
MLCPGLGNSLHSGIVAHYIHNFASEQQKQEWLPKMAKGELVGGLAITEPGAGSDVQSIRTAARKEGGDYVINGAKTYITN
GSTANLICVVVKTDPNLGAKGISIIVVETDKVEGFRRGRTLSKVGLHSQDTAELFFDDVRVPQANLLGNVEGQGFKQLMK
ELSRERVITAFMSMACMERAIEETLKFAADRKVFGQTLLSMQNTRFKLAECETKLTLAKAMLSHCSASLLEGQLSSEIAA
MAKWWITDACGQVVDECVQLHGGAGFMLEYPIARLYQNVRIHRILAGTNEIMKEVIARELEKRAV

Sequences:

>Translated_385_residues
MQNAPWMNPELETLRDSARRFYEAELLPHEERWAQQQCVDRDVWYKAAEAGLLCVGIPEEYGGGGGNFLHEAVIFAEQGR
MLCPGLGNSLHSGIVAHYIHNFASEQQKQEWLPKMAKGELVGGLAITEPGAGSDVQSIRTAARKEGGDYVINGAKTYITN
GSTANLICVVVKTDPNLGAKGISIIVVETDKVEGFRRGRTLSKVGLHSQDTAELFFDDVRVPQANLLGNVEGQGFKQLMK
ELSRERVITAFMSMACMERAIEETLKFAADRKVFGQTLLSMQNTRFKLAECETKLTLAKAMLSHCSASLLEGQLSSEIAA
MAKWWITDACGQVVDECVQLHGGAGFMLEYPIARLYQNVRIHRILAGTNEIMKEVIARELEKRAV
>Mature_385_residues
MQNAPWMNPELETLRDSARRFYEAELLPHEERWAQQQCVDRDVWYKAAEAGLLCVGIPEEYGGGGGNFLHEAVIFAEQGR
MLCPGLGNSLHSGIVAHYIHNFASEQQKQEWLPKMAKGELVGGLAITEPGAGSDVQSIRTAARKEGGDYVINGAKTYITN
GSTANLICVVVKTDPNLGAKGISIIVVETDKVEGFRRGRTLSKVGLHSQDTAELFFDDVRVPQANLLGNVEGQGFKQLMK
ELSRERVITAFMSMACMERAIEETLKFAADRKVFGQTLLSMQNTRFKLAECETKLTLAKAMLSHCSASLLEGQLSSEIAA
MAKWWITDACGQVVDECVQLHGGAGFMLEYPIARLYQNVRIHRILAGTNEIMKEVIARELEKRAV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=377, Percent_Identity=44.2970822281167, Blast_Score=335, Evalue=5e-92,
Organism=Homo sapiens, GI4557231, Length=368, Percent_Identity=33.1521739130435, Blast_Score=199, Evalue=3e-51,
Organism=Homo sapiens, GI187960098, Length=368, Percent_Identity=33.1521739130435, Blast_Score=199, Evalue=4e-51,
Organism=Homo sapiens, GI7656849, Length=380, Percent_Identity=33.1578947368421, Blast_Score=199, Evalue=4e-51,
Organism=Homo sapiens, GI226958412, Length=377, Percent_Identity=30.2387267904509, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI226958414, Length=341, Percent_Identity=31.3782991202346, Blast_Score=192, Evalue=6e-49,
Organism=Homo sapiens, GI4557233, Length=378, Percent_Identity=33.8624338624339, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI4501859, Length=370, Percent_Identity=28.6486486486486, Blast_Score=188, Evalue=6e-48,
Organism=Homo sapiens, GI76496475, Length=377, Percent_Identity=34.4827586206897, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI4557235, Length=377, Percent_Identity=34.4827586206897, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI21361497, Length=387, Percent_Identity=30.749354005168, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI4503943, Length=377, Percent_Identity=27.8514588859416, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI7669494, Length=356, Percent_Identity=28.3707865168539, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI211971008, Length=413, Percent_Identity=26.3922518159806, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI48976061, Length=413, Percent_Identity=26.3922518159806, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI38505218, Length=290, Percent_Identity=28.9655172413793, Blast_Score=99, Evalue=7e-21,
Organism=Escherichia coli, GI87081958, Length=349, Percent_Identity=29.2263610315186, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1786223, Length=365, Percent_Identity=28.2191780821918, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI87082384, Length=293, Percent_Identity=28.6689419795222, Blast_Score=75, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17533517, Length=381, Percent_Identity=35.9580052493438, Blast_Score=220, Evalue=9e-58,
Organism=Caenorhabditis elegans, GI17538396, Length=379, Percent_Identity=33.245382585752, Blast_Score=219, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17551932, Length=375, Percent_Identity=33.6, Blast_Score=211, Evalue=4e-55,
Organism=Caenorhabditis elegans, GI17505929, Length=374, Percent_Identity=33.6898395721925, Blast_Score=210, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17570075, Length=374, Percent_Identity=32.8877005347594, Blast_Score=204, Evalue=6e-53,
Organism=Caenorhabditis elegans, GI17569725, Length=376, Percent_Identity=33.2446808510638, Blast_Score=196, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17534899, Length=371, Percent_Identity=31.266846361186, Blast_Score=186, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17508101, Length=374, Percent_Identity=28.6096256684492, Blast_Score=177, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI17506239, Length=368, Percent_Identity=27.1739130434783, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI71985184, Length=348, Percent_Identity=32.183908045977, Blast_Score=150, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI71990804, Length=278, Percent_Identity=30.9352517985612, Blast_Score=147, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI71982178, Length=277, Percent_Identity=25.9927797833935, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI32563615, Length=230, Percent_Identity=29.1304347826087, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71985192, Length=302, Percent_Identity=31.7880794701987, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17534353, Length=385, Percent_Identity=26.4935064935065, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17562446, Length=300, Percent_Identity=29.3333333333333, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17531909, Length=244, Percent_Identity=22.1311475409836, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI21355753, Length=383, Percent_Identity=31.8537859007833, Blast_Score=191, Evalue=5e-49,
Organism=Drosophila melanogaster, GI24666513, Length=391, Percent_Identity=29.156010230179, Blast_Score=185, Evalue=4e-47,
Organism=Drosophila melanogaster, GI24660351, Length=375, Percent_Identity=31.4666666666667, Blast_Score=184, Evalue=7e-47,
Organism=Drosophila melanogaster, GI21356377, Length=372, Percent_Identity=29.8387096774194, Blast_Score=171, Evalue=8e-43,
Organism=Drosophila melanogaster, GI24646207, Length=381, Percent_Identity=31.2335958005249, Blast_Score=167, Evalue=9e-42,
Organism=Drosophila melanogaster, GI281363737, Length=338, Percent_Identity=32.5443786982249, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI19920834, Length=392, Percent_Identity=27.2959183673469, Blast_Score=125, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42537; Mature: 42537

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNAPWMNPELETLRDSARRFYEAELLPHEERWAQQQCVDRDVWYKAAEAGLLCVGIPEE
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHCCEEEEECCHH
YGGGGGNFLHEAVIFAEQGRMLCPGLGNSLHSGIVAHYIHNFASEQQKQEWLPKMAKGEL
HCCCCHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
VGGLAITEPGAGSDVQSIRTAARKEGGDYVINGAKTYITNGSTANLICVVVKTDPNLGAK
ECCEEEECCCCCCHHHHHHHHHHHCCCCEEEECCEEEEECCCCCEEEEEEEECCCCCCCC
GISIIVVETDKVEGFRRGRTLSKVGLHSQDTAELFFDDVRVPQANLLGNVEGQGFKQLMK
CEEEEEEECCHHHHHHHCCCHHHHCCCCCCHHHHHHHHCCCCHHHHCCCCCCHHHHHHHH
ELSRERVITAFMSMACMERAIEETLKFAADRKVFGQTLLSMQNTRFKLAECETKLTLAKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHH
MLSHCSASLLEGQLSSEIAAMAKWWITDACGQVVDECVQLHGGAGFMLEYPIARLYQNVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
IHRILAGTNEIMKEVIARELEKRAV
HHHHHHCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQNAPWMNPELETLRDSARRFYEAELLPHEERWAQQQCVDRDVWYKAAEAGLLCVGIPEE
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHCCEEEEECCHH
YGGGGGNFLHEAVIFAEQGRMLCPGLGNSLHSGIVAHYIHNFASEQQKQEWLPKMAKGEL
HCCCCHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
VGGLAITEPGAGSDVQSIRTAARKEGGDYVINGAKTYITNGSTANLICVVVKTDPNLGAK
ECCEEEECCCCCCHHHHHHHHHHHCCCCEEEECCEEEEECCCCCEEEEEEEECCCCCCCC
GISIIVVETDKVEGFRRGRTLSKVGLHSQDTAELFFDDVRVPQANLLGNVEGQGFKQLMK
CEEEEEEECCHHHHHHHCCCHHHHCCCCCCHHHHHHHHCCCCHHHHCCCCCCHHHHHHHH
ELSRERVITAFMSMACMERAIEETLKFAADRKVFGQTLLSMQNTRFKLAECETKLTLAKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHH
MLSHCSASLLEGQLSSEIAAMAKWWITDACGQVVDECVQLHGGAGFMLEYPIARLYQNVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
IHRILAGTNEIMKEVIARELEKRAV
HHHHHHCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]