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The map label for this gene is bcd [H]

Identifier: 94314344

GI number: 94314344

Start: 2172794

End: 2173948

Strand: Direct

Name: bcd [H]

Synonym: Rmet_5425

Alternate gene names: 94314344

Gene position: 2172794-2173948 (Clockwise)

Preceding gene: 94314343

Following gene: 94314345

Centisome position: 84.21

GC content: 64.33

Gene sequence:

>1155_bases
ATGGATTTCAAACTCAGCGAGGAACATCAGGCTTTCGCGGACTCGGTTGCCCGTTTTGCGCAGGACAAACTCAAGGATGG
CGCGCTGGCCCGGGCACATTCGCCCCACTACCCCTGGGACACGGCGGCGCTGCTCGCCGAGCAGGGGCTGCTGGGCATCG
CCTTCTCCGAAGAAGATGGCGGCCAGGGCGGCACGCTGATGCACGCGGTGCTGGCGATCGAGCAAATCGCGCTGGTTTGC
CCCAGGAGCGCCGACATCGTCCAGGCTGGCAACTTCGGGCCGATTCGGACGTTCGTGGAATACGCATCGCCCGAGCAGAA
AGCGCGATACCTGCCGGACCTCCTGGCTGGCCGCAAGGTGGTCTCGCTGGGCATGAGCGAACCCGATGCCGGGTCCGCCG
TGACCGAGTTGAAAACCAGCGCGCGCCTCGACGGTGACAGCTACGTCATCAACGGCAGCAAGGTTTTCTCCACGCACAGC
CCCGACGCCGAGCTTTTCCTGATCTATGTACGCTTCGGCCCGGGCGTCGGTGGCATCGGCTCCGTGCTGGTCGAGCGCGG
CACGCCCGGCTTCCAGGTCGGCGAGCCATCATCGTTCATGAACGGCGAGCAGTGGTCGCAGCTCTACTTCGATGATTGCC
GTATCCCGGTGGAAAACGTGCTGCTCGGACCGGGCGGTTTCAAGAAGCAGATCTCGGGGTTCAACGTCGAGCGTCTGGGC
AACTCGTCACGCGCGCTGGCGCTGGGGCGCCACGCGTTCAACGTGGCCCGGGAACATGCCATGACCCGCAAGCAGTTCGG
CCGCGAGCTCTGCGAATTCCAGGGCATTCAGTGGAAGTTCGCGGATATGGCGATGAAGCTGGAGCAGGCGCAGATGATGC
TGTATCGCGCCGCTCTCGAAGGCGAGCACGGACTGCCCAGCGCGCAGAGCACGGCTATGGCCAAGCTGGCCTGCAACATG
GCTGGCTGGGAGGTTTCCAATGAAGCGCTGCAGGTGATGGGCGGCATGGGCTTCAGCCAGGAATCTCTCGTGGAGTACTG
CGTGCGGCGGACGCGCGGCTGGATGATCGCCGGTGGCTCCATCGAAATCCTGAAGAACCGCGTCGCTGAAGGCGTCTTCG
GCAGGACGTTCTCGCAGCGCCCGACCAACGGCTGA

Upstream 100 bases:

>100_bases
AGTATTTGTTCGGGCTGCTGACAAAAGTCGAAGTTCTCAGGCCTCGGGGCCACAGGCACCATTCCGACGTCACACATCCC
GAACAGACGCAGGAACACAC

Downstream 100 bases:

>100_bases
CAATCGGCTGAAACTCGGCGCTTGGCAAGCGGGGCCGGGATGAATCTCGGCCTCCGTCATCCCCCCTTCCTGCGTGCGCT
CTCCGCCACGCACGTGATCC

Product: putative Butyryl-CoA dehydrogenase

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MDFKLSEEHQAFADSVARFAQDKLKDGALARAHSPHYPWDTAALLAEQGLLGIAFSEEDGGQGGTLMHAVLAIEQIALVC
PRSADIVQAGNFGPIRTFVEYASPEQKARYLPDLLAGRKVVSLGMSEPDAGSAVTELKTSARLDGDSYVINGSKVFSTHS
PDAELFLIYVRFGPGVGGIGSVLVERGTPGFQVGEPSSFMNGEQWSQLYFDDCRIPVENVLLGPGGFKKQISGFNVERLG
NSSRALALGRHAFNVAREHAMTRKQFGRELCEFQGIQWKFADMAMKLEQAQMMLYRAALEGEHGLPSAQSTAMAKLACNM
AGWEVSNEALQVMGGMGFSQESLVEYCVRRTRGWMIAGGSIEILKNRVAEGVFGRTFSQRPTNG

Sequences:

>Translated_384_residues
MDFKLSEEHQAFADSVARFAQDKLKDGALARAHSPHYPWDTAALLAEQGLLGIAFSEEDGGQGGTLMHAVLAIEQIALVC
PRSADIVQAGNFGPIRTFVEYASPEQKARYLPDLLAGRKVVSLGMSEPDAGSAVTELKTSARLDGDSYVINGSKVFSTHS
PDAELFLIYVRFGPGVGGIGSVLVERGTPGFQVGEPSSFMNGEQWSQLYFDDCRIPVENVLLGPGGFKKQISGFNVERLG
NSSRALALGRHAFNVAREHAMTRKQFGRELCEFQGIQWKFADMAMKLEQAQMMLYRAALEGEHGLPSAQSTAMAKLACNM
AGWEVSNEALQVMGGMGFSQESLVEYCVRRTRGWMIAGGSIEILKNRVAEGVFGRTFSQRPTNG
>Mature_384_residues
MDFKLSEEHQAFADSVARFAQDKLKDGALARAHSPHYPWDTAALLAEQGLLGIAFSEEDGGQGGTLMHAVLAIEQIALVC
PRSADIVQAGNFGPIRTFVEYASPEQKARYLPDLLAGRKVVSLGMSEPDAGSAVTELKTSARLDGDSYVINGSKVFSTHS
PDAELFLIYVRFGPGVGGIGSVLVERGTPGFQVGEPSSFMNGEQWSQLYFDDCRIPVENVLLGPGGFKKQISGFNVERLG
NSSRALALGRHAFNVAREHAMTRKQFGRELCEFQGIQWKFADMAMKLEQAQMMLYRAALEGEHGLPSAQSTAMAKLACNM
AGWEVSNEALQVMGGMGFSQESLVEYCVRRTRGWMIAGGSIEILKNRVAEGVFGRTFSQRPTNG

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=374, Percent_Identity=32.620320855615, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI4501859, Length=374, Percent_Identity=32.3529411764706, Blast_Score=178, Evalue=7e-45,
Organism=Homo sapiens, GI7656849, Length=374, Percent_Identity=28.6096256684492, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI4557231, Length=376, Percent_Identity=29.7872340425532, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI187960098, Length=376, Percent_Identity=29.7872340425532, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI226958412, Length=383, Percent_Identity=28.7206266318538, Blast_Score=152, Evalue=7e-37,
Organism=Homo sapiens, GI21361497, Length=346, Percent_Identity=31.7919075144509, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI226958414, Length=341, Percent_Identity=29.3255131964809, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI76496475, Length=385, Percent_Identity=29.6103896103896, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI4557235, Length=385, Percent_Identity=29.6103896103896, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI4501857, Length=390, Percent_Identity=27.4358974358974, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI7669494, Length=349, Percent_Identity=25.5014326647564, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4503943, Length=349, Percent_Identity=25.5014326647564, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI38505218, Length=300, Percent_Identity=28.3333333333333, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI211971008, Length=297, Percent_Identity=27.2727272727273, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI48976061, Length=297, Percent_Identity=27.2727272727273, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1786223, Length=370, Percent_Identity=28.9189189189189, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI87081958, Length=373, Percent_Identity=27.6139410187668, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI87082384, Length=262, Percent_Identity=25.9541984732824, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17506239, Length=374, Percent_Identity=31.283422459893, Blast_Score=177, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI17508101, Length=376, Percent_Identity=31.1170212765957, Blast_Score=175, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17569725, Length=395, Percent_Identity=30.126582278481, Blast_Score=172, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI17533517, Length=346, Percent_Identity=30.9248554913295, Blast_Score=165, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI17538396, Length=390, Percent_Identity=30.7692307692308, Blast_Score=162, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17570075, Length=384, Percent_Identity=28.125, Blast_Score=161, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI17534899, Length=393, Percent_Identity=30.2798982188295, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI71990804, Length=275, Percent_Identity=36, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71985184, Length=276, Percent_Identity=31.8840579710145, Blast_Score=140, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI17551932, Length=374, Percent_Identity=28.0748663101604, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17534353, Length=345, Percent_Identity=26.3768115942029, Blast_Score=121, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17505929, Length=374, Percent_Identity=28.6096256684492, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=31.1688311688312, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI71985192, Length=234, Percent_Identity=30.7692307692308, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71982178, Length=276, Percent_Identity=26.8115942028986, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17562446, Length=267, Percent_Identity=26.9662921348315, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21356377, Length=377, Percent_Identity=31.0344827586207, Blast_Score=181, Evalue=6e-46,
Organism=Drosophila melanogaster, GI24666513, Length=375, Percent_Identity=31.4666666666667, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24646207, Length=374, Percent_Identity=28.8770053475936, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI21355753, Length=326, Percent_Identity=32.2085889570552, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24660351, Length=381, Percent_Identity=28.3464566929134, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI281363737, Length=378, Percent_Identity=29.1005291005291, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI19920834, Length=248, Percent_Identity=26.6129032258064, Blast_Score=99, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 41727; Mature: 41727

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFKLSEEHQAFADSVARFAQDKLKDGALARAHSPHYPWDTAALLAEQGLLGIAFSEEDG
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEECCCCC
GQGGTLMHAVLAIEQIALVCPRSADIVQAGNFGPIRTFVEYASPEQKARYLPDLLAGRKV
CCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCE
VSLGMSEPDAGSAVTELKTSARLDGDSYVINGSKVFSTHSPDAELFLIYVRFGPGVGGIG
EECCCCCCCCCHHHHHHHHHHCCCCCCEEECCCEEEECCCCCCEEEEEEEEECCCCCCHH
SVLVERGTPGFQVGEPSSFMNGEQWSQLYFDDCRIPVENVLLGPGGFKKQISGFNVERLG
HHHHHCCCCCCCCCCCCHHCCCHHHHHHHHHCCCCCHHHEEECCCCCHHHHCCCCHHHCC
NSSRALALGRHAFNVAREHAMTRKQFGRELCEFQGIQWKFADMAMKLEQAQMMLYRAALE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHC
GEHGLPSAQSTAMAKLACNMAGWEVSNEALQVMGGMGFSQESLVEYCVRRTRGWMIAGGS
CCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEECCC
IEILKNRVAEGVFGRTFSQRPTNG
HHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MDFKLSEEHQAFADSVARFAQDKLKDGALARAHSPHYPWDTAALLAEQGLLGIAFSEEDG
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEECCCCC
GQGGTLMHAVLAIEQIALVCPRSADIVQAGNFGPIRTFVEYASPEQKARYLPDLLAGRKV
CCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCE
VSLGMSEPDAGSAVTELKTSARLDGDSYVINGSKVFSTHSPDAELFLIYVRFGPGVGGIG
EECCCCCCCCCHHHHHHHHHHCCCCCCEEECCCEEEECCCCCCEEEEEEEEECCCCCCHH
SVLVERGTPGFQVGEPSSFMNGEQWSQLYFDDCRIPVENVLLGPGGFKKQISGFNVERLG
HHHHHCCCCCCCCCCCCHHCCCHHHHHHHHHCCCCCHHHEEECCCCCHHHHCCCCHHHCC
NSSRALALGRHAFNVAREHAMTRKQFGRELCEFQGIQWKFADMAMKLEQAQMMLYRAALE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHC
GEHGLPSAQSTAMAKLACNMAGWEVSNEALQVMGGMGFSQESLVEYCVRRTRGWMIAGGS
CCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEECCC
IEILKNRVAEGVFGRTFSQRPTNG
HHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]