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The map label for this gene is atsA [H]

Identifier: 94314342

GI number: 94314342

Start: 2169176

End: 2171158

Strand: Reverse

Name: atsA [H]

Synonym: Rmet_5423

Alternate gene names: 94314342

Gene position: 2171158-2169176 (Counterclockwise)

Preceding gene: 291481570

Following gene: 94314341

Centisome position: 84.15

GC content: 65.0

Gene sequence:

>1983_bases
ATGAAAAGAACGAAAGCGGCTGCCTTCCCACAACCGGTGCGACGCGCGCTGGCCACCCTTTGCCTGGGCGCGGTGGCGCT
GGCCGCAGGTTGCGGGAGCGATGGCACCGAGAGCGGCACGCTGGCCGTGGACAGTGGCACGCCGGTCACCACCCCACCGC
AGGTCGTGGCGAAGAAGCCCAACATCCTGTTCATCATGGCCGATGACCTCGGGTACTCGGACCTGGGCGCGTTCGGCAGC
GAGATCCGCACGCCCAACATTGACGCGCTGGTGCGCGATGGTCGCATCCTGACCAATCACCACACCGCCGCCGTGTGCGC
GGTGACGCGTTCGATGATCATCTCCGGCACCGACCATCATCTGGTCGGGCAGGGCACGATGGCGAACAGCGACCCCAATT
ACGTGGACGAGAACGGCAAGCCCATTCCCGGCTACGAGGGCTACCTGAACGATCGCGCGCTCTCGATCGCGCAACTGCTG
AAGGACGGCGGCTATCACACCTACATGGCCGGCAAGTGGCACCTTGGCAGTGGCTTGCCCAACGCAACGAACCAGGGCGC
GGCGGTTGGCACATCGGCGCCGGGGCAGACGCCGGTCTCGTGGGGTTTCGAGAAGAGCTACGCGCTGCTCGGCGGCGGCG
GGGATCACTTCGGCCGTAACGGCGCAACCGCCTACGTGGAGGACGATCACTACGTCACGCCCAACACGACCAGCTTCTTC
TCGTCGGACTTCTATACCTCGACGATCATCAAGTACATCGACTCGAGCACGGGCAAGAACACCGATGGCAAGCCATTCTT
CGCCTACCTGACCTACCAGGCGCCACACTCGCCGCTGCAGGCGCCGGCAGGCTATATCGATCGCTACAAGGGCGTCTATG
ACGCGGGCTACGAGCCGATACGCGCCGCACGGCTGGCCCGGCAGAAAGCGCTCGGCCTGATCCCGGCCGACTTCACGCCC
AATCCGGGTCGTGATGAAACACTCGCCGTCACGCCGGCCACGGCGAACTGGGGCACGCCTCAGGCGTCGTACGTCAGCGC
CACGCGCAGCGTCGCGCAAGGCGGTGTGGATACCCGTGTGATGAACGCGAACAAGAAGTGGGACAGCCTGACTGCGGACC
AGAAGAAGGCGCAGGCCCGCTACATGGAAATTTTCGCGGCCATGGTGGAGAACCTGGACGACAATGTTGGCCGGCTGGTG
CAGCACCTCAAGGACATTGGCGAGTACGAAAACACCGTCATCGTGTTTCAGTCCGACAATGGCCCCGAAGCCAGCTACTA
CGAGTTCAGCGGCAAGTACGACCAGGACTACGACACGAAGAACGCCGATCCGGCCGTGTTCCCCACGCTCGGCACGCCGG
CCTACAAGGGCACGGCCACGATCGACTACGGCCAGCGCTGGGCGGAAGTCAGCGCCACGCCATTCAAGCTGTGGAAGTCG
TTCCCGTCAGAGGGCGGGCACTCCGTGCCGACCATCGTCAAGTTGGCCGGCACGGCATCCGCGCCGCCGCAGAGCAGGGT
GACGGCCTTCACCCACGTGGTAGACCTGGCGCCGACGTTCCTGGACCTCGCCGGTGTCAGCGCACCGACCAAGCCGGCCG
CGCCGCTCTACGACAGCAAGGGGATCGACCGCAATGCGGGCAAGGTCGTGTACGACGGTCGCAATGTCTATCCGATCACC
GGCCTGTCGTTGCTGCCGACGCTGCAGGGCAAGACAACCGGCCCGTCGCGCACCACGTTCTCCGAGGAGCTGTACGGTCG
CACCTATGTCTATAGCGACAACTGGAAGGCCGTATGGATCGAGCCGCCGTTCGGCCCGGCAGACGGCGAATGGACGCTCT
ACGACATTCGCGCCGATCGCGGCGAGACGAACAACCTCGCAGCGCAGCGCCCGGATGTGCTGAGCGACCTGAAGGGCAAG
TGGAACGACTACGCCGCGCGCGTGGGCGCGGTGCTGCCCAAGGTACCGGGCATGATCTACTGA

Upstream 100 bases:

>100_bases
GCTTCGATAATGCATATGCGAAACCATTCGTTCTGTGAAGCCGATGTGATTCATAGCATGGCTCTCTTTCTCAACCCCGA
CGTTGAAGCGAGAGACGCAT

Downstream 100 bases:

>100_bases
CATTGCGGAACCCGTGGACATGGTCGTGAACGTGTTGCGAAACAGGGGACGCTGGCGCACGCCGCTGGCGGTAGCTGGGC
TGGCATTCGCGGTGGGTGTC

Product: Arylsulfatase

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 660; Mature: 660

Protein sequence:

>660_residues
MKRTKAAAFPQPVRRALATLCLGAVALAAGCGSDGTESGTLAVDSGTPVTTPPQVVAKKPNILFIMADDLGYSDLGAFGS
EIRTPNIDALVRDGRILTNHHTAAVCAVTRSMIISGTDHHLVGQGTMANSDPNYVDENGKPIPGYEGYLNDRALSIAQLL
KDGGYHTYMAGKWHLGSGLPNATNQGAAVGTSAPGQTPVSWGFEKSYALLGGGGDHFGRNGATAYVEDDHYVTPNTTSFF
SSDFYTSTIIKYIDSSTGKNTDGKPFFAYLTYQAPHSPLQAPAGYIDRYKGVYDAGYEPIRAARLARQKALGLIPADFTP
NPGRDETLAVTPATANWGTPQASYVSATRSVAQGGVDTRVMNANKKWDSLTADQKKAQARYMEIFAAMVENLDDNVGRLV
QHLKDIGEYENTVIVFQSDNGPEASYYEFSGKYDQDYDTKNADPAVFPTLGTPAYKGTATIDYGQRWAEVSATPFKLWKS
FPSEGGHSVPTIVKLAGTASAPPQSRVTAFTHVVDLAPTFLDLAGVSAPTKPAAPLYDSKGIDRNAGKVVYDGRNVYPIT
GLSLLPTLQGKTTGPSRTTFSEELYGRTYVYSDNWKAVWIEPPFGPADGEWTLYDIRADRGETNNLAAQRPDVLSDLKGK
WNDYAARVGAVLPKVPGMIY

Sequences:

>Translated_660_residues
MKRTKAAAFPQPVRRALATLCLGAVALAAGCGSDGTESGTLAVDSGTPVTTPPQVVAKKPNILFIMADDLGYSDLGAFGS
EIRTPNIDALVRDGRILTNHHTAAVCAVTRSMIISGTDHHLVGQGTMANSDPNYVDENGKPIPGYEGYLNDRALSIAQLL
KDGGYHTYMAGKWHLGSGLPNATNQGAAVGTSAPGQTPVSWGFEKSYALLGGGGDHFGRNGATAYVEDDHYVTPNTTSFF
SSDFYTSTIIKYIDSSTGKNTDGKPFFAYLTYQAPHSPLQAPAGYIDRYKGVYDAGYEPIRAARLARQKALGLIPADFTP
NPGRDETLAVTPATANWGTPQASYVSATRSVAQGGVDTRVMNANKKWDSLTADQKKAQARYMEIFAAMVENLDDNVGRLV
QHLKDIGEYENTVIVFQSDNGPEASYYEFSGKYDQDYDTKNADPAVFPTLGTPAYKGTATIDYGQRWAEVSATPFKLWKS
FPSEGGHSVPTIVKLAGTASAPPQSRVTAFTHVVDLAPTFLDLAGVSAPTKPAAPLYDSKGIDRNAGKVVYDGRNVYPIT
GLSLLPTLQGKTTGPSRTTFSEELYGRTYVYSDNWKAVWIEPPFGPADGEWTLYDIRADRGETNNLAAQRPDVLSDLKGK
WNDYAARVGAVLPKVPGMIY
>Mature_660_residues
MKRTKAAAFPQPVRRALATLCLGAVALAAGCGSDGTESGTLAVDSGTPVTTPPQVVAKKPNILFIMADDLGYSDLGAFGS
EIRTPNIDALVRDGRILTNHHTAAVCAVTRSMIISGTDHHLVGQGTMANSDPNYVDENGKPIPGYEGYLNDRALSIAQLL
KDGGYHTYMAGKWHLGSGLPNATNQGAAVGTSAPGQTPVSWGFEKSYALLGGGGDHFGRNGATAYVEDDHYVTPNTTSFF
SSDFYTSTIIKYIDSSTGKNTDGKPFFAYLTYQAPHSPLQAPAGYIDRYKGVYDAGYEPIRAARLARQKALGLIPADFTP
NPGRDETLAVTPATANWGTPQASYVSATRSVAQGGVDTRVMNANKKWDSLTADQKKAQARYMEIFAAMVENLDDNVGRLV
QHLKDIGEYENTVIVFQSDNGPEASYYEFSGKYDQDYDTKNADPAVFPTLGTPAYKGTATIDYGQRWAEVSATPFKLWKS
FPSEGGHSVPTIVKLAGTASAPPQSRVTAFTHVVDLAPTFLDLAGVSAPTKPAAPLYDSKGIDRNAGKVVYDGRNVYPIT
GLSLLPTLQGKTTGPSRTTFSEELYGRTYVYSDNWKAVWIEPPFGPADGEWTLYDIRADRGETNNLAAQRPDVLSDLKGK
WNDYAARVGAVLPKVPGMIY

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI109389362, Length=253, Percent_Identity=29.6442687747036, Blast_Score=113, Evalue=6e-25,
Organism=Homo sapiens, GI38569405, Length=251, Percent_Identity=28.6852589641434, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI38569407, Length=251, Percent_Identity=28.6852589641434, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI59797060, Length=234, Percent_Identity=26.4957264957265, Blast_Score=90, Evalue=8e-18,
Organism=Homo sapiens, GI157266309, Length=157, Percent_Identity=33.7579617834395, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI31742482, Length=155, Percent_Identity=34.8387096774194, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI71852584, Length=160, Percent_Identity=35, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI71852586, Length=160, Percent_Identity=35, Blast_Score=77, Evalue=6e-14,
Organism=Homo sapiens, GI53831991, Length=130, Percent_Identity=36.1538461538462, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI146229331, Length=123, Percent_Identity=34.9593495934959, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI146229329, Length=123, Percent_Identity=34.9593495934959, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI6005990, Length=123, Percent_Identity=34.9593495934959, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI146229324, Length=123, Percent_Identity=34.9593495934959, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI58743319, Length=120, Percent_Identity=36.6666666666667, Blast_Score=68, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115533416, Length=239, Percent_Identity=28.4518828451883, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115533418, Length=227, Percent_Identity=26.8722466960352, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281366397, Length=275, Percent_Identity=29.4545454545455, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281366395, Length=275, Percent_Identity=29.4545454545455, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24666163, Length=275, Percent_Identity=29.4545454545455, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24666109, Length=260, Percent_Identity=28.4615384615385, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281363223, Length=231, Percent_Identity=30.3030303030303, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24666175, Length=254, Percent_Identity=25.1968503937008, Blast_Score=82, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 70891; Mature: 70891

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00149 SULFATASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRTKAAAFPQPVRRALATLCLGAVALAAGCGSDGTESGTLAVDSGTPVTTPPQVVAKKP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCHHHHCCCC
NILFIMADDLGYSDLGAFGSEIRTPNIDALVRDGRILTNHHTAAVCAVTRSMIISGTDHH
CEEEEEECCCCCHHHHHHHHHCCCCCHHEEEECCEEEECCCHHHHHHHHHHHHCCCCCCE
LVGQGTMANSDPNYVDENGKPIPGYEGYLNDRALSIAQLLKDGGYHTYMAGKWHLGSGLP
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECEEECCCCCC
NATNQGAAVGTSAPGQTPVSWGFEKSYALLGGGGDHFGRNGATAYVEDDHYVTPNTTSFF
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEECCCEEECCCCHHHH
SSDFYTSTIIKYIDSSTGKNTDGKPFFAYLTYQAPHSPLQAPAGYIDRYKGVYDAGYEPI
CCCHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHCCHHHCCCCHH
RAARLARQKALGLIPADFTPNPGRDETLAVTPATANWGTPQASYVSATRSVAQGGVDTRV
HHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEE
MNANKKWDSLTADQKKAQARYMEIFAAMVENLDDNVGRLVQHLKDIGEYENTVIVFQSDN
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECCC
GPEASYYEFSGKYDQDYDTKNADPAVFPTLGTPAYKGTATIDYGQRWAEVSATPFKLWKS
CCCCCEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEECCCCHHHHCCCCHHHHHHH
FPSEGGHSVPTIVKLAGTASAPPQSRVTAFTHVVDLAPTFLDLAGVSAPTKPAAPLYDSK
CCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GIDRNAGKVVYDGRNVYPITGLSLLPTLQGKTTGPSRTTFSEELYGRTYVYSDNWKAVWI
CCCCCCCEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEECCCEEEEE
EPPFGPADGEWTLYDIRADRGETNNLAAQRPDVLSDLKGKWNDYAARVGAVLPKVPGMIY
ECCCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKRTKAAAFPQPVRRALATLCLGAVALAAGCGSDGTESGTLAVDSGTPVTTPPQVVAKKP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCHHHHCCCC
NILFIMADDLGYSDLGAFGSEIRTPNIDALVRDGRILTNHHTAAVCAVTRSMIISGTDHH
CEEEEEECCCCCHHHHHHHHHCCCCCHHEEEECCEEEECCCHHHHHHHHHHHHCCCCCCE
LVGQGTMANSDPNYVDENGKPIPGYEGYLNDRALSIAQLLKDGGYHTYMAGKWHLGSGLP
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECEEECCCCCC
NATNQGAAVGTSAPGQTPVSWGFEKSYALLGGGGDHFGRNGATAYVEDDHYVTPNTTSFF
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEECCCEEECCCCHHHH
SSDFYTSTIIKYIDSSTGKNTDGKPFFAYLTYQAPHSPLQAPAGYIDRYKGVYDAGYEPI
CCCHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHCCHHHCCCCHH
RAARLARQKALGLIPADFTPNPGRDETLAVTPATANWGTPQASYVSATRSVAQGGVDTRV
HHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEE
MNANKKWDSLTADQKKAQARYMEIFAAMVENLDDNVGRLVQHLKDIGEYENTVIVFQSDN
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECCC
GPEASYYEFSGKYDQDYDTKNADPAVFPTLGTPAYKGTATIDYGQRWAEVSATPFKLWKS
CCCCCEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEECCCCHHHHCCCCHHHHHHH
FPSEGGHSVPTIVKLAGTASAPPQSRVTAFTHVVDLAPTFLDLAGVSAPTKPAAPLYDSK
CCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GIDRNAGKVVYDGRNVYPITGLSLLPTLQGKTTGPSRTTFSEELYGRTYVYSDNWKAVWI
CCCCCCCEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEECCCEEEEE
EPPFGPADGEWTLYDIRADRGETNNLAAQRPDVLSDLKGKWNDYAARVGAVLPKVPGMIY
ECCCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7744061; 10984043 [H]