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The map label for this gene is hmuS [H]

Identifier: 94314294

GI number: 94314294

Start: 2101577

End: 2102617

Strand: Direct

Name: hmuS [H]

Synonym: Rmet_5375

Alternate gene names: 94314294

Gene position: 2101577-2102617 (Clockwise)

Preceding gene: 94314293

Following gene: 94314295

Centisome position: 81.45

GC content: 66.47

Gene sequence:

>1041_bases
ATGAACATGGAACAGCAAAGCATCGACAGCTTGCGCCAACGCCACGGCGCCCTGGTCGAAGAACATCCAAAGTTGCGGAT
CCGCGAACGCGCGCAGCGCCTCCGCGTGTCCGAGGCAGAACTGGTGGCGGCGGGCTGTGGCGTCGCATCACGGCAACTGG
GCGGAACCGCGCAGGCGTTGTTCCGCGATCTCGGCACGCTGGGGTCGGTCATGGCGCTCTCGCGCAACGACCACGCCGTG
CACGAGCGTCACGGCCAGTATCAGAGCATCGAGGCGAATGGCCCGGTCGGCATCGTGCTGGGGCCGGACATCGACCTGCG
CATGTTCTTCGGCGGCTGGAAACACTTCTACGCCGTAACCGAAAACGGTCGCGACAGCATCCAGTTCTTCGACAAGGCGG
GCGAGGCGGTACACAAGATCTACCGGACCGACCAGACCGATGCCACCGCGTGGTCGGCCTACATCGACCGCCACGCCGCG
CAGGAGATCGCGCCGGTGCGGGTCGAGGGCTTTGACCGGATCGACGAGGCGGACTCCCCCGCCGACGGCGAGGCCCTGCG
CGCGCACTGGCGCGCGCTCAAGGACACGCACGACTTCTTTGCGATGCTTCGCCAGTTCAAGGTATCGCGGCTGGGCGCGC
TGCGTGCGGTCGGCCCAGATCTGGCGCAACGGGTGGACAAGCGCGCCGTGGAGACCGTGCTGGAACACTCCGCCGCCACC
GGCCTGTCGATCATGTGCTTCGTCGCCAATCGCGGCATCGTGCAGATCCACACGGGCGCCGTGAAGAAGCTGCTGCGGAC
GGGGCCGTGGTTCAACGTGCTCGATGAGACCTTCAACCTGCACCTGAACACCGAGGCGGTGGCGTCAAGCTGGGTGGTCA
ACAAACCCACGGTGGACGGCTGGGTGACGTCGCTCGAACTGTACGGTGAGGACGGCGGGATGATCGTCCAGTTCTTCGGC
GAGCGCAAACCCGGGCAGCCCGAACTGCCGGAATGGCGCCATCTGCTCGAGTCGCTGTGCCCGCAGGCACTCGCGGCCTG
A

Upstream 100 bases:

>100_bases
ACCTGACGAAGATCGCCTATGCGGACCCGAACGTGAATAGCAGCACCCAGACCTGGACGATCAACTTCGACGTTCAGCCC
TGATCAGCCCCTCCGAATAC

Downstream 100 bases:

>100_bases
TTGTCCAGGAGGTTTGGCATGAAAATCCTGCAGTCCGCACTCATTACTGCGCTGATGCCGCTGCTTTGCGCGGCCGGCGT
TGCCCACGCCGCGCCGCCAG

Product: hemin transport protein HmuS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MNMEQQSIDSLRQRHGALVEEHPKLRIRERAQRLRVSEAELVAAGCGVASRQLGGTAQALFRDLGTLGSVMALSRNDHAV
HERHGQYQSIEANGPVGIVLGPDIDLRMFFGGWKHFYAVTENGRDSIQFFDKAGEAVHKIYRTDQTDATAWSAYIDRHAA
QEIAPVRVEGFDRIDEADSPADGEALRAHWRALKDTHDFFAMLRQFKVSRLGALRAVGPDLAQRVDKRAVETVLEHSAAT
GLSIMCFVANRGIVQIHTGAVKKLLRTGPWFNVLDETFNLHLNTEAVASSWVVNKPTVDGWVTSLELYGEDGGMIVQFFG
ERKPGQPELPEWRHLLESLCPQALAA

Sequences:

>Translated_346_residues
MNMEQQSIDSLRQRHGALVEEHPKLRIRERAQRLRVSEAELVAAGCGVASRQLGGTAQALFRDLGTLGSVMALSRNDHAV
HERHGQYQSIEANGPVGIVLGPDIDLRMFFGGWKHFYAVTENGRDSIQFFDKAGEAVHKIYRTDQTDATAWSAYIDRHAA
QEIAPVRVEGFDRIDEADSPADGEALRAHWRALKDTHDFFAMLRQFKVSRLGALRAVGPDLAQRVDKRAVETVLEHSAAT
GLSIMCFVANRGIVQIHTGAVKKLLRTGPWFNVLDETFNLHLNTEAVASSWVVNKPTVDGWVTSLELYGEDGGMIVQFFG
ERKPGQPELPEWRHLLESLCPQALAA
>Mature_346_residues
MNMEQQSIDSLRQRHGALVEEHPKLRIRERAQRLRVSEAELVAAGCGVASRQLGGTAQALFRDLGTLGSVMALSRNDHAV
HERHGQYQSIEANGPVGIVLGPDIDLRMFFGGWKHFYAVTENGRDSIQFFDKAGEAVHKIYRTDQTDATAWSAYIDRHAA
QEIAPVRVEGFDRIDEADSPADGEALRAHWRALKDTHDFFAMLRQFKVSRLGALRAVGPDLAQRVDKRAVETVLEHSAAT
GLSIMCFVANRGIVQIHTGAVKKLLRTGPWFNVLDETFNLHLNTEAVASSWVVNKPTVDGWVTSLELYGEDGGMIVQFFG
ERKPGQPELPEWRHLLESLCPQALAA

Specific function: Part of the binding-protein-dependent transport system for hemin [H]

COG id: COG3720

COG function: function code P; Putative heme degradation protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To Y.enterocolitica hemS [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007845 [H]

Pfam domain/function: PF05171 HemS [H]

EC number: NA

Molecular weight: Translated: 38468; Mature: 38468

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMEQQSIDSLRQRHGALVEEHPKLRIRERAQRLRVSEAELVAAGCGVASRQLGGTAQAL
CCCCHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHCCCHHHHHHHCCCHHHHHCCCHHHHH
FRDLGTLGSVMALSRNDHAVHERHGQYQSIEANGPVGIVLGPDIDLRMFFGGWKHFYAVT
HHHHHHHHHHHHHCCCCCHHHHHCCCEEEEECCCCEEEEECCCCCEEEEECCCEEEEEEE
ENGRDSIQFFDKAGEAVHKIYRTDQTDATAWSAYIDRHAAQEIAPVRVEGFDRIDEADSP
CCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCC
ADGEALRAHWRALKDTHDFFAMLRQFKVSRLGALRAVGPDLAQRVDKRAVETVLEHSAAT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
GLSIMCFVANRGIVQIHTGAVKKLLRTGPWFNVLDETFNLHLNTEAVASSWVVNKPTVDG
CCEEEEEEECCCEEEEEHHHHHHHHHCCCCHHHHHHHHEEEECHHHHHHCCCCCCCCCCH
WVTSLELYGEDGGMIVQFFGERKPGQPELPEWRHLLESLCPQALAA
HEEEEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNMEQQSIDSLRQRHGALVEEHPKLRIRERAQRLRVSEAELVAAGCGVASRQLGGTAQAL
CCCCHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHCCCHHHHHHHCCCHHHHHCCCHHHHH
FRDLGTLGSVMALSRNDHAVHERHGQYQSIEANGPVGIVLGPDIDLRMFFGGWKHFYAVT
HHHHHHHHHHHHHCCCCCHHHHHCCCEEEEECCCCEEEEECCCCCEEEEECCCEEEEEEE
ENGRDSIQFFDKAGEAVHKIYRTDQTDATAWSAYIDRHAAQEIAPVRVEGFDRIDEADSP
CCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCC
ADGEALRAHWRALKDTHDFFAMLRQFKVSRLGALRAVGPDLAQRVDKRAVETVLEHSAAT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
GLSIMCFVANRGIVQIHTGAVKKLLRTGPWFNVLDETFNLHLNTEAVASSWVVNKPTVDG
CCEEEEEEECCCEEEEEHHHHHHHHHCCCCHHHHHHHHEEEECHHHHHHCCCCCCCCCCH
WVTSLELYGEDGGMIVQFFGERKPGQPELPEWRHLLESLCPQALAA
HEEEEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9026634; 11586360; 12142430 [H]