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The map label for this gene is cirA [H]

Identifier: 94314292

GI number: 94314292

Start: 2098197

End: 2100182

Strand: Direct

Name: cirA [H]

Synonym: Rmet_5373

Alternate gene names: 94314292

Gene position: 2098197-2100182 (Clockwise)

Preceding gene: 94314291

Following gene: 94314293

Centisome position: 81.32

GC content: 65.56

Gene sequence:

>1986_bases
ATGCGTTTGAAATGCCTCGCCGTCGTCGCCGGCACCCTGCTCTCCTCCACACCCCACCTCCGGGCGCAAACGGTTGGAAC
GGCGGACCCACTACCTACAGTCGTCGTGACAGGCACCCGTTCCGAGAAAACACTCGATGAAACGCCGATCCGCACGGAGG
TCGTCGACCGTCAGGAGATCGAACGCACGCACGCCCGCACGCTGAAGGACGCCCTGGAGAACGTGCCCGGCCTGCAGTTG
CGCGAGATCCACGGCAAGTCCGGCTATGAGGTGACCCTGCAAGGGATGACCAGCGACCAGGTGCTTATCCTGGTCGACGG
CCTGCCGATCACGGCCAGCACCGGGTCGACCGTTGACGTTTCCCAGTACCTGCTGGCCGAAGTCGACCACGTCGAGGTGG
TCAAGGGCGCCAGTTCCGCGCAGTACGGCAGCTCGGCGATGGGCGGGGTGATCAATGTCATCACGCGGCCCATCTCGCGC
GGATTCTCGGCTGCCGCGACAGCCGATGCAGGCACCTATGGCAGCCAGAACGCCGACGGCTCGCCCGGTTCCCTGCATGG
CAACATCCGGCTCGAAGGCGGCAACGAACAGTTCCGCGCACGCGTCACCGCCGACGCGCTCGACAACAAGGGCTATGCCG
TGGAACCCGACGGCTGGACACGGCACGGCGACAAGATTCGCCGCGAGCAGTATGCCGGTCGCCTCGAATGGTTGCCCAGC
GCCGCCGGCAGCTTCTGGTTCGACGCCAGCGCCTATCGCGAGACCGACGAACAACGCTACCAGTACTACGCGCCGCCCAA
CTACGTCCCGCAGCGCAAGACAGAGGACATCGATCGCAACCGCTACACATATGGCGGCCAATGGCGCTTCGGCAATGGCG
TGCGCGCCCGCCTGGCCGGGGTGCACGAGACCTACGACAGCACCTCGCGCGAGTACTCGAACGGCTTCCAGACCGCGACG
CGCAATGCCGCGCAGCAGACCGACCATGTCTCCGCGCAGTTCGACATGCCAGCCTGGTATCGACAGCTCTGGCAGTTCGG
CGGCGACTTCCACCGCGAAACGCTCGACCAGAACGTCAACGGCACGTCCGAACTGGCCGGCAAGGGCAGCGCCGAACGGC
AGGCCGGCGAGCTCTACCTGCAGAACGACATCCTCTTCAACGAGACGTGGGAAATGGTCGTCGGCCTGCGCGGCCAGCAT
GACTCTGACTTCGGCGCGCACTTCGCGCCCAAGGTGGGCGTGCGCGCGAACCTGCTGTCGAACGACACCTGGAAGGGCGT
GCTGCGCGCCAACTACGGCCAGGGCTACCGCGTGCCGAACCTGAAGGAACGGCACTACCTGTTCGATCACAGCTCGCTTG
GCTACATCGTCCTCGGCAACCCGAACCTCAAACCAGAATCGTCGAACAGCTTCCAGCTCGGCGGGCAGCTCACGTGGCGA
GACCGCGTCACGCTCGATGCCAACCTGTTCTACAACCACGTGGCGGATCTGATCCAGACCGACATGACCAACTTCACGAT
GGTCAACGGCATCGCGGTCTACACCTACCGCAACGTGGCACGCGCCCGCACCCAGGGCGCTGAGACAGCGCTGCGCTGGC
GCGCGACCAACCAGTTGAATCTGACAGCCGCCTACACCTACACGTCGACCGAGGATCTGAACACAGGTAGCGAACTGACC
CGCCGGCCGCGCCATATGGGCCGCGTCGGCGCGGACTGGCGCGTGCTGCCCGCCACCGAGCTATCCGCGCGGGCGCGCTT
CCAGAGCAGCGAGCTGACCGACTCGGCCACCGGCGCGCGCTCGCCCGGCTGGGGCACGCTGGATCTGGTGCTGAACCAGA
AGCTCGACCGCAACGTGACCGCTTTCGTCGGCGTGAACAACCTGTTCAACCGCCAACGCGATTTCGCAAATGCCAGTGAC
TTCGGGCCGGTGGCGGGCCGCTTCATCTATCTGGGCGCACGCTTCAACGTGGACGTCGCCCGCTAA

Upstream 100 bases:

>100_bases
ATCTGACACAACATGTAAGTAAATTTACAACTTAAATACGAATCGTTATCATTCGTACTTCTGTTTGCATTTGACATGGC
AGTGAGCCGCCCCCTCCGAT

Downstream 100 bases:

>100_bases
TCAGAAACAAACCAGAGACAAACGGGGAAATCAACAATGAAAGCCAGACTCGCATCGCATCACACCACGCTGCGCCTGCT
TGGCGCTGCCGTGCTGACAA

Product: TonB-dependent outer-membrane transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 661; Mature: 661

Protein sequence:

>661_residues
MRLKCLAVVAGTLLSSTPHLRAQTVGTADPLPTVVVTGTRSEKTLDETPIRTEVVDRQEIERTHARTLKDALENVPGLQL
REIHGKSGYEVTLQGMTSDQVLILVDGLPITASTGSTVDVSQYLLAEVDHVEVVKGASSAQYGSSAMGGVINVITRPISR
GFSAAATADAGTYGSQNADGSPGSLHGNIRLEGGNEQFRARVTADALDNKGYAVEPDGWTRHGDKIRREQYAGRLEWLPS
AAGSFWFDASAYRETDEQRYQYYAPPNYVPQRKTEDIDRNRYTYGGQWRFGNGVRARLAGVHETYDSTSREYSNGFQTAT
RNAAQQTDHVSAQFDMPAWYRQLWQFGGDFHRETLDQNVNGTSELAGKGSAERQAGELYLQNDILFNETWEMVVGLRGQH
DSDFGAHFAPKVGVRANLLSNDTWKGVLRANYGQGYRVPNLKERHYLFDHSSLGYIVLGNPNLKPESSNSFQLGGQLTWR
DRVTLDANLFYNHVADLIQTDMTNFTMVNGIAVYTYRNVARARTQGAETALRWRATNQLNLTAAYTYTSTEDLNTGSELT
RRPRHMGRVGADWRVLPATELSARARFQSSELTDSATGARSPGWGTLDLVLNQKLDRNVTAFVGVNNLFNRQRDFANASD
FGPVAGRFIYLGARFNVDVAR

Sequences:

>Translated_661_residues
MRLKCLAVVAGTLLSSTPHLRAQTVGTADPLPTVVVTGTRSEKTLDETPIRTEVVDRQEIERTHARTLKDALENVPGLQL
REIHGKSGYEVTLQGMTSDQVLILVDGLPITASTGSTVDVSQYLLAEVDHVEVVKGASSAQYGSSAMGGVINVITRPISR
GFSAAATADAGTYGSQNADGSPGSLHGNIRLEGGNEQFRARVTADALDNKGYAVEPDGWTRHGDKIRREQYAGRLEWLPS
AAGSFWFDASAYRETDEQRYQYYAPPNYVPQRKTEDIDRNRYTYGGQWRFGNGVRARLAGVHETYDSTSREYSNGFQTAT
RNAAQQTDHVSAQFDMPAWYRQLWQFGGDFHRETLDQNVNGTSELAGKGSAERQAGELYLQNDILFNETWEMVVGLRGQH
DSDFGAHFAPKVGVRANLLSNDTWKGVLRANYGQGYRVPNLKERHYLFDHSSLGYIVLGNPNLKPESSNSFQLGGQLTWR
DRVTLDANLFYNHVADLIQTDMTNFTMVNGIAVYTYRNVARARTQGAETALRWRATNQLNLTAAYTYTSTEDLNTGSELT
RRPRHMGRVGADWRVLPATELSARARFQSSELTDSATGARSPGWGTLDLVLNQKLDRNVTAFVGVNNLFNRQRDFANASD
FGPVAGRFIYLGARFNVDVAR
>Mature_661_residues
MRLKCLAVVAGTLLSSTPHLRAQTVGTADPLPTVVVTGTRSEKTLDETPIRTEVVDRQEIERTHARTLKDALENVPGLQL
REIHGKSGYEVTLQGMTSDQVLILVDGLPITASTGSTVDVSQYLLAEVDHVEVVKGASSAQYGSSAMGGVINVITRPISR
GFSAAATADAGTYGSQNADGSPGSLHGNIRLEGGNEQFRARVTADALDNKGYAVEPDGWTRHGDKIRREQYAGRLEWLPS
AAGSFWFDASAYRETDEQRYQYYAPPNYVPQRKTEDIDRNRYTYGGQWRFGNGVRARLAGVHETYDSTSREYSNGFQTAT
RNAAQQTDHVSAQFDMPAWYRQLWQFGGDFHRETLDQNVNGTSELAGKGSAERQAGELYLQNDILFNETWEMVVGLRGQH
DSDFGAHFAPKVGVRANLLSNDTWKGVLRANYGQGYRVPNLKERHYLFDHSSLGYIVLGNPNLKPESSNSFQLGGQLTWR
DRVTLDANLFYNHVADLIQTDMTNFTMVNGIAVYTYRNVARARTQGAETALRWRATNQLNLTAAYTYTSTEDLNTGSELT
RRPRHMGRVGADWRVLPATELSARARFQSSELTDSATGARSPGWGTLDLVLNQKLDRNVTAFVGVNNLFNRQRDFANASD
FGPVAGRFIYLGARFNVDVAR

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=623, Percent_Identity=25.6821829855538, Blast_Score=160, Evalue=3e-40,
Organism=Escherichia coli, GI1790405, Length=152, Percent_Identity=35.5263157894737, Blast_Score=83, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 73253; Mature: 73253

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLKCLAVVAGTLLSSTPHLRAQTVGTADPLPTVVVTGTRSEKTLDETPIRTEVVDRQEI
CCEEEHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEECCCCCCCCCCCCCHHHHHCHHHH
ERTHARTLKDALENVPGLQLREIHGKSGYEVTLQGMTSDQVLILVDGLPITASTGSTVDV
HHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCCCCEEEEECCCEEECCCCCCCHH
SQYLLAEVDHVEVVKGASSAQYGSSAMGGVINVITRPISRGFSAAATADAGTYGSQNADG
HHHHHHHCCHHHEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
SPGSLHGNIRLEGGNEQFRARVTADALDNKGYAVEPDGWTRHGDKIRREQYAGRLEWLPS
CCCEEEEEEEEECCCCEEEEEEEHHHHCCCCCEECCCCCCCCHHHHHHHHHCCHHHCCCC
AAGSFWFDASAYRETDEQRYQYYAPPNYVPQRKTEDIDRNRYTYGGQWRFGNGVRARLAG
CCCCCEECCHHHHCCCHHCEEEECCCCCCCCCCCCCCCCCCCEECCEEEECCCCEEHHHH
VHETYDSTSREYSNGFQTATRNAAQQTDHVSAQFDMPAWYRQLWQFGGDFHRETLDQNVN
HHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHCCHHHHHHHHCCCC
GTSELAGKGSAERQAGELYLQNDILFNETWEMVVGLRGQHDSDFGAHFAPKVGVRANLLS
CCHHHCCCCCCCCCCCCEEEECCEEECCCHHEEEECCCCCCCCCCCCCCCCCCCEEEECC
NDTWKGVLRANYGQGYRVPNLKERHYLFDHSSLGYIVLGNPNLKPESSNSFQLGGQLTWR
CCCCCEEEEECCCCCCCCCCCCCCEEEECCCCCCEEEECCCCCCCCCCCCEEECCEEEEC
DRVTLDANLFYNHVADLIQTDMTNFTMVNGIAVYTYRNVARARTQGAETALRWRATNQLN
CCEEEEHHHHHHHHHHHHHHCCCCEEEECCEEEEEEHHHHHHHHCCCHHEEEEECCCEEE
LTAAYTYTSTEDLNTGSELTRRPRHMGRVGADWRVLPATELSARARFQSSELTDSATGAR
EEEEEEEECCCCCCCCHHHHHCHHHHCCCCCCCEEECCCHHHHHHHCCCCCCCCCCCCCC
SPGWGTLDLVLNQKLDRNVTAFVGVNNLFNRQRDFANASDFGPVAGRFIYLGARFNVDVA
CCCCCEEEEEECCCCCCCEEEEEECHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEEEEEC
R
C
>Mature Secondary Structure
MRLKCLAVVAGTLLSSTPHLRAQTVGTADPLPTVVVTGTRSEKTLDETPIRTEVVDRQEI
CCEEEHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEECCCCCCCCCCCCCHHHHHCHHHH
ERTHARTLKDALENVPGLQLREIHGKSGYEVTLQGMTSDQVLILVDGLPITASTGSTVDV
HHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCCCCEEEEECCCEEECCCCCCCHH
SQYLLAEVDHVEVVKGASSAQYGSSAMGGVINVITRPISRGFSAAATADAGTYGSQNADG
HHHHHHHCCHHHEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
SPGSLHGNIRLEGGNEQFRARVTADALDNKGYAVEPDGWTRHGDKIRREQYAGRLEWLPS
CCCEEEEEEEEECCCCEEEEEEEHHHHCCCCCEECCCCCCCCHHHHHHHHHCCHHHCCCC
AAGSFWFDASAYRETDEQRYQYYAPPNYVPQRKTEDIDRNRYTYGGQWRFGNGVRARLAG
CCCCCEECCHHHHCCCHHCEEEECCCCCCCCCCCCCCCCCCCEECCEEEECCCCEEHHHH
VHETYDSTSREYSNGFQTATRNAAQQTDHVSAQFDMPAWYRQLWQFGGDFHRETLDQNVN
HHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHCCHHHHHHHHCCCC
GTSELAGKGSAERQAGELYLQNDILFNETWEMVVGLRGQHDSDFGAHFAPKVGVRANLLS
CCHHHCCCCCCCCCCCCEEEECCEEECCCHHEEEECCCCCCCCCCCCCCCCCCCEEEECC
NDTWKGVLRANYGQGYRVPNLKERHYLFDHSSLGYIVLGNPNLKPESSNSFQLGGQLTWR
CCCCCEEEEECCCCCCCCCCCCCCEEEECCCCCCEEEECCCCCCCCCCCCEEECCEEEEC
DRVTLDANLFYNHVADLIQTDMTNFTMVNGIAVYTYRNVARARTQGAETALRWRATNQLN
CCEEEEHHHHHHHHHHHHHHCCCCEEEECCEEEEEEHHHHHHHHCCCHHEEEEECCCEEE
LTAAYTYTSTEDLNTGSELTRRPRHMGRVGADWRVLPATELSARARFQSSELTDSATGAR
EEEEEEEECCCCCCCCHHHHHCHHHHCCCCCCCEEECCCHHHHHHHCCCCCCCCCCCCCC
SPGWGTLDLVLNQKLDRNVTAFVGVNNLFNRQRDFANASDFGPVAGRFIYLGARFNVDVA
CCCCCEEEEEECCCCCCCEEEEEECHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEEEEEC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]