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The map label for this gene is rhtC [H]

Identifier: 94314034

GI number: 94314034

Start: 1809310

End: 1809921

Strand: Direct

Name: rhtC [H]

Synonym: Rmet_5115

Alternate gene names: 94314034

Gene position: 1809310-1809921 (Clockwise)

Preceding gene: 94314033

Following gene: 94314036

Centisome position: 70.13

GC content: 65.03

Gene sequence:

>612_bases
ATGGAATACATCAACACCCTGCTGGCTCTGACCGGCGTCATGATGTTGAGCGTCGCCAGCCCGGGACCGAATTTCATGAT
CGTCACATCGACGGCGGTCGCGTCTCGGCGTGCAGGCGTGATCACCGGCCTCGCGCTTGGCGCAGCCTCGGGCACCTGGG
CCCTGATCGCGATCGCCGGACTCGGCCTGATCGTCACGCATGTGGCATGGATCGGCACGGCGCTCCGGATTGCTGGCGCC
GCCTACCTGATCTGGCTCGGGGCAAAGATGATCCTGACCGCGCGCCATCCGCTGAATGCTCCGACCCTCGTTGCGCCATC
CGGCTGGACCGCCGCGAAGAAGGGCTATGCCGTCAGCATGACCAACCCCAAGGCCGTGGCGTTCTACGGCAGCATCTTCG
CGTTGATGGTCCCCGCTCACGCGCCGGCATGGTTCCACGTCGCTGTCATCGCCATTGCAGTCGCGGTATCGTCTGCATGG
TACTGCGGCATGGCGCTGCTCGCCTCACACCCTGCGGTTCACCGGTTACTGATGCGGCGCAAGGCCGTGCTGGATTCCGT
GGTTGGAGGACTGCTGATAGTCCTTGGCGGACGGATGCTGGCGGCGCGCTGA

Upstream 100 bases:

>100_bases
TTTTGCCCGCTGCGCCGCCACGCATCGTCAGGTAGGATTGGCGCTCCCCCTGATCGCGTCGGCCGGGCCCACAGGCCCCG
TGTGCTGCGGAGAACACAAG

Downstream 100 bases:

>100_bases
AGCCTTGCGTTCCCCACCAATTCACCAGGAATGCGACGGGGGCGGGAGAGGATCGTCATCGACCACCATCGGCCTACTGA
TAGTCGAAAGTGAAAACCAT

Product: L-lysine exporter protein LysE/YggA

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MEYINTLLALTGVMMLSVASPGPNFMIVTSTAVASRRAGVITGLALGAASGTWALIAIAGLGLIVTHVAWIGTALRIAGA
AYLIWLGAKMILTARHPLNAPTLVAPSGWTAAKKGYAVSMTNPKAVAFYGSIFALMVPAHAPAWFHVAVIAIAVAVSSAW
YCGMALLASHPAVHRLLMRRKAVLDSVVGGLLIVLGGRMLAAR

Sequences:

>Translated_203_residues
MEYINTLLALTGVMMLSVASPGPNFMIVTSTAVASRRAGVITGLALGAASGTWALIAIAGLGLIVTHVAWIGTALRIAGA
AYLIWLGAKMILTARHPLNAPTLVAPSGWTAAKKGYAVSMTNPKAVAFYGSIFALMVPAHAPAWFHVAVIAIAVAVSSAW
YCGMALLASHPAVHRLLMRRKAVLDSVVGGLLIVLGGRMLAAR
>Mature_203_residues
MEYINTLLALTGVMMLSVASPGPNFMIVTSTAVASRRAGVITGLALGAASGTWALIAIAGLGLIVTHVAWIGTALRIAGA
AYLIWLGAKMILTARHPLNAPTLVAPSGWTAAKKGYAVSMTNPKAVAFYGSIFALMVPAHAPAWFHVAVIAIAVAVSSAW
YCGMALLASHPAVHRLLMRRKAVLDSVVGGLLIVLGGRMLAAR

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=198, Percent_Identity=31.3131313131313, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1786522, Length=209, Percent_Identity=28.2296650717703, Blast_Score=89, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 20980; Mature: 20980

Theoretical pI: Translated: 11.55; Mature: 11.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYINTLLALTGVMMLSVASPGPNFMIVTSTAVASRRAGVITGLALGAASGTWALIAIAG
CHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHCHHHHHHHHCCCCCHHHHHHHHH
LGLIVTHVAWIGTALRIAGAAYLIWLGAKMILTARHPLNAPTLVAPSGWTAAKKGYAVSM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEECCCCCCHHCCCEEEEE
TNPKAVAFYGSIFALMVPAHAPAWFHVAVIAIAVAVSSAWYCGMALLASHPAVHRLLMRR
CCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
KAVLDSVVGGLLIVLGGRMLAAR
HHHHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure
MEYINTLLALTGVMMLSVASPGPNFMIVTSTAVASRRAGVITGLALGAASGTWALIAIAG
CHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHCHHHHHHHHCCCCCHHHHHHHHH
LGLIVTHVAWIGTALRIAGAAYLIWLGAKMILTARHPLNAPTLVAPSGWTAAKKGYAVSM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEECCCCCCHHCCCEEEEE
TNPKAVAFYGSIFALMVPAHAPAWFHVAVIAIAVAVSSAWYCGMALLASHPAVHRLLMRR
CCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
KAVLDSVVGGLLIVLGGRMLAAR
HHHHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]