BacMap

Definition	Cupriavidus metallidurans CH34 megaplasmid, complete sequence.
Accession	NC_007974
Length	2,580,084

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The map label for this gene is fabG [H]

Identifier: 94313950

GI number: 94313950

Start: 1713304

End: 1714128

Strand: Direct

Name: fabG [H]

Synonym: Rmet_5028

Alternate gene names: 94313950

Gene position: 1713304-1714128 (Clockwise)

Preceding gene: 94313949

Following gene: 291481555

Centisome position: 66.4

GC content: 64.85

Gene sequence:

>825_bases
ATGGGAGCACTCGAAGGCAAGGTGGCACTGGTCACCGGTTCCGGCCGTGGCATCGGCCACGCCATCGCACAACGCCTGGC
ACGCGAAGGCGCGCGCCTGGTCATCAATGATCTGGATGCGGAGCCCGCCCACGCCACCGTGGAAGCGTTGCGCAAGATGG
GCGTGGAAGCCGTGGCCTGCGTAGGCAACGTGACGGCACCCGACTTTGCCGACCGCTTTATCGGCACGGCGATGTCCGAG
TTCAAGGGCATCGACATCATCGTCAACAACGCCGGGTTCACCTGGGACGACGTGGTGCAGAAGATGAGCGACGAGCAGTG
GCACGCGATTCTCGACTGCCACATGACGGCCCCGTTCCGCATCCTGCGGGCCGCGTATCCGCACATCAAGGCGCTGCACG
CTGCTGACAAGGAAGCGGGCCGCGAGGTCTATCGCAAGATCGTCAACATCTCGTCGACGTCGGCGCTGAACGGCAATGCC
GGGCAGATCAACTACTCGGGCGCCAAGGCCGGCGTGATTGGCATGACGCGCGCCATCGCACGCGAGTGGGGCCGCTTCAA
CGTCAACGTGAACGCCGTGGCATTCGGCCTGATCCATACGCGCATGACCTCGGCCGACGCGAATGCGGGCGCCACCGTGA
ACATTGAAGGCCGCGAGATTCGCGTCGGGCTGAATCCGGAGATGCTCAAGTCGCACGCTCAGCGCAATCCGCTCGGCCGG
GGCGGCACGCCGGAAGAAGCCGCTGGCGGCGTCTACCTGTTCTGCTCGCCGGATTCGAACTACATCACGGGCCAGACCAT
CGCCGTGGCCGGTAACCTGCAGTAA

Upstream 100 bases:

>100_bases
CACCGCGAACCAGTACGACGAAACGAGGATCCTGGGCGACGCAGTCGTCGCCCTGTAACAAGCTGTTCAAGCCACCCATC
ATCACCAAAGGAGTCAAGAC

Downstream 100 bases:

>100_bases
CAGGCAGGCTGTTGATCCGAAGCGCGCCAGCGCCAGCCATGACTGCCCGTCATGCGCAGACGTCGGCACCAATGAAAAAG
CCCCGGCCGCTCATCTGCGG

Product: 3-oxoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MGALEGKVALVTGSGRGIGHAIAQRLAREGARLVINDLDAEPAHATVEALRKMGVEAVACVGNVTAPDFADRFIGTAMSE
FKGIDIIVNNAGFTWDDVVQKMSDEQWHAILDCHMTAPFRILRAAYPHIKALHAADKEAGREVYRKIVNISSTSALNGNA
GQINYSGAKAGVIGMTRAIAREWGRFNVNVNAVAFGLIHTRMTSADANAGATVNIEGREIRVGLNPEMLKSHAQRNPLGR
GGTPEEAAGGVYLFCSPDSNYITGQTIAVAGNLQ

Sequences:

>Translated_274_residues
MGALEGKVALVTGSGRGIGHAIAQRLAREGARLVINDLDAEPAHATVEALRKMGVEAVACVGNVTAPDFADRFIGTAMSE
FKGIDIIVNNAGFTWDDVVQKMSDEQWHAILDCHMTAPFRILRAAYPHIKALHAADKEAGREVYRKIVNISSTSALNGNA
GQINYSGAKAGVIGMTRAIAREWGRFNVNVNAVAFGLIHTRMTSADANAGATVNIEGREIRVGLNPEMLKSHAQRNPLGR
GGTPEEAAGGVYLFCSPDSNYITGQTIAVAGNLQ
>Mature_273_residues
GALEGKVALVTGSGRGIGHAIAQRLAREGARLVINDLDAEPAHATVEALRKMGVEAVACVGNVTAPDFADRFIGTAMSEF
KGIDIIVNNAGFTWDDVVQKMSDEQWHAILDCHMTAPFRILRAAYPHIKALHAADKEAGREVYRKIVNISSTSALNGNAG
QINYSGAKAGVIGMTRAIAREWGRFNVNVNAVAFGLIHTRMTSADANAGATVNIEGREIRVGLNPEMLKSHAQRNPLGRG
GTPEEAAGGVYLFCSPDSNYITGQTIAVAGNLQ

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=269, Percent_Identity=31.2267657992565, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI4504505, Length=200, Percent_Identity=35.5, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI15277342, Length=278, Percent_Identity=32.0143884892086, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI5031737, Length=273, Percent_Identity=28.9377289377289, Blast_Score=107, Evalue=8e-24,
Organism=Homo sapiens, GI19923817, Length=277, Percent_Identity=27.0758122743682, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI40254992, Length=270, Percent_Identity=30.7407407407407, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI126723750, Length=273, Percent_Identity=28.5714285714286, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI10190704, Length=272, Percent_Identity=29.4117647058824, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI4758504, Length=209, Percent_Identity=28.7081339712919, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI33667109, Length=223, Percent_Identity=27.3542600896861, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI126723191, Length=203, Percent_Identity=30.0492610837438, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI66933014, Length=274, Percent_Identity=27.007299270073, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI83715985, Length=187, Percent_Identity=29.4117647058824, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI4503301, Length=273, Percent_Identity=26.007326007326, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI59889578, Length=243, Percent_Identity=27.5720164609054, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787335, Length=270, Percent_Identity=35.1851851851852, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1789208, Length=270, Percent_Identity=32.5925925925926, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790717, Length=273, Percent_Identity=29.6703296703297, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87082160, Length=269, Percent_Identity=29.368029739777, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787905, Length=272, Percent_Identity=28.6764705882353, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI87082100, Length=276, Percent_Identity=29.3478260869565, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789378, Length=274, Percent_Identity=26.6423357664234, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI2367175, Length=274, Percent_Identity=28.1021897810219, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788459, Length=269, Percent_Identity=28.2527881040892, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1789057, Length=269, Percent_Identity=23.4200743494424, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI2367365, Length=271, Percent_Identity=26.1992619926199, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=270, Percent_Identity=34.0740740740741, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17561402, Length=274, Percent_Identity=32.4817518248175, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI25147288, Length=269, Percent_Identity=34.2007434944238, Blast_Score=127, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17568967, Length=199, Percent_Identity=33.6683417085427, Blast_Score=120, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17562910, Length=280, Percent_Identity=32.1428571428571, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17560676, Length=273, Percent_Identity=28.5714285714286, Blast_Score=104, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17562904, Length=282, Percent_Identity=28.3687943262411, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17560332, Length=289, Percent_Identity=30.1038062283737, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17544670, Length=282, Percent_Identity=28.3687943262411, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17538486, Length=282, Percent_Identity=28.7234042553192, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=281, Percent_Identity=29.1814946619217, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=278, Percent_Identity=28.0575539568345, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17536025, Length=287, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=276, Percent_Identity=27.1739130434783, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17538182, Length=282, Percent_Identity=27.6595744680851, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=286, Percent_Identity=28.6713286713287, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=279, Percent_Identity=26.5232974910394, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=278, Percent_Identity=29.136690647482, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17536651, Length=280, Percent_Identity=28.2142857142857, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=284, Percent_Identity=28.8732394366197, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17565030, Length=276, Percent_Identity=29.7101449275362, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=274, Percent_Identity=27.007299270073, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=287, Percent_Identity=27.5261324041812, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=279, Percent_Identity=27.5985663082437, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=179, Percent_Identity=29.0502793296089, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=179, Percent_Identity=29.0502793296089, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=284, Percent_Identity=28.8732394366197, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=278, Percent_Identity=28.7769784172662, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=278, Percent_Identity=24.8201438848921, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17564282, Length=203, Percent_Identity=28.0788177339901, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=274, Percent_Identity=25.1824817518248, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=265, Percent_Identity=24.9056603773585, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=210, Percent_Identity=32.3809523809524, Blast_Score=122, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24639444, Length=279, Percent_Identity=33.6917562724014, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI18859837, Length=198, Percent_Identity=35.8585858585859, Blast_Score=117, Evalue=6e-27,
Organism=Drosophila melanogaster, GI21355319, Length=280, Percent_Identity=29.2857142857143, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI23397609, Length=269, Percent_Identity=29.368029739777, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI17737361, Length=210, Percent_Identity=30, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24644339, Length=272, Percent_Identity=27.2058823529412, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28571526, Length=276, Percent_Identity=26.4492753623188, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357041, Length=276, Percent_Identity=25, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24644337, Length=275, Percent_Identity=26.9090909090909, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24643142, Length=208, Percent_Identity=26.9230769230769, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21357673, Length=201, Percent_Identity=25.3731343283582, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 29077; Mature: 28946

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGALEGKVALVTGSGRGIGHAIAQRLAREGARLVINDLDAEPAHATVEALRKMGVEAVAC
CCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEH
VGNVTAPDFADRFIGTAMSEFKGIDIIVNNAGFTWDDVVQKMSDEQWHAILDCHMTAPFR
CCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCCEEEEEEECCCCHHH
ILRAAYPHIKALHAADKEAGREVYRKIVNISSTSALNGNAGQINYSGAKAGVIGMTRAIA
HHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHH
REWGRFNVNVNAVAFGLIHTRMTSADANAGATVNIEGREIRVGLNPEMLKSHAQRNPLGR
HHCCCEEEEEHHEEEEHHHHHHCCCCCCCCCEEEECCCEEEECCCHHHHHHHHHCCCCCC
GGTPEEAAGGVYLFCSPDSNYITGQTIAVAGNLQ
CCCCCHHCCCEEEEECCCCCEECCCEEEEECCCC
>Mature Secondary Structure 
GALEGKVALVTGSGRGIGHAIAQRLAREGARLVINDLDAEPAHATVEALRKMGVEAVAC
CCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEH
VGNVTAPDFADRFIGTAMSEFKGIDIIVNNAGFTWDDVVQKMSDEQWHAILDCHMTAPFR
CCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCCEEEEEEECCCCHHH
ILRAAYPHIKALHAADKEAGREVYRKIVNISSTSALNGNAGQINYSGAKAGVIGMTRAIA
HHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHH
REWGRFNVNVNAVAFGLIHTRMTSADANAGATVNIEGREIRVGLNPEMLKSHAQRNPLGR
HHCCCEEEEEHHEEEEHHHHHHCCCCCCCCCEEEECCCEEEECCCHHHHHHHHHCCCCCC
GGTPEEAAGGVYLFCSPDSNYITGQTIAVAGNLQ
CCCCCHHCCCEEEEECCCCCEECCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]