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The map label for this gene is ykgC [H]

Identifier: 94313933

GI number: 94313933

Start: 1689509

End: 1690888

Strand: Reverse

Name: ykgC [H]

Synonym: Rmet_5011

Alternate gene names: 94313933

Gene position: 1690888-1689509 (Counterclockwise)

Preceding gene: 291481554

Following gene: 94313931

Centisome position: 65.54

GC content: 65.14

Gene sequence:

>1380_bases
ATGGCTCAGAGATTCGACGCGATCATCATCGGCACCGGACAGGCCGGCCCCGCACTCGCGGCGAGGCTGGCCGGCGCGGG
CATGAAGCTGGCGGTTATCGAGCGCGGGCGGTTTGGCGGTACCTGCGTGAACACCGGCTGCATCCCCACCAAGGCGTTGA
TCGCGAGTGCGTACGCCGCCCAACTGGCGCGGCGGGCTGCCGAGTACGGCGTGACCATCGGTGGGCCGGTCGCGGTCGAC
ATGAGGCAGGTAAAGGCACGCAAGGACGAAATCTCGGGCAGGTCCAGCCAGGGCGTGGAGCAGTGGATGCGCGGGCTGGA
CAACGTCACCGTCCATCAGGGGCATGCCCGCTTCGAGCACGCGCGCGGCGTGCGGGTCAACGGGGAGTTGCTGGAGGCCG
ACCAGATCTTCATTAACGTTGGCGGCCGGGCGCTGATTCCACCGATGCCAGGGCTGGATCAGGTGTCATACCTGACCAAT
TCAAGCATGATGGAAGTCGATTTCCTGCCGGAGCATCTGATCATCGTTGGCGGCAGCTATATCGGCCTTGAATTCGGCCA
GATGTACCGGCGGTTCGGGGCCAGGGTGACCATCGTCGAGAAAGGCCCGAGACTGATTCAGCGGGAAGACGAGGACGTGT
CGCAAGCCGTGCGGGAGATTCTCGAACGCGAGGGCATCGAGGTTCGGCTCGACGCCAACTGTCTGAGCGCGCGCAAGGAC
GGTGACCATATTGCCGTCGGGCTCGATTGCGCGGGCGGGGCGCCTGAAGTTCACGGCTCGCACCTGTTGATGGCCGTCGG
GCGCGTGCCCAATACGGACGATCTGGGGCTCGACAAGGCAGGTATCGAGACGGATGCCCGGGGCTACATCAAGGTGGACG
ATCAACTGCGCACCAGCGTCCCCGGCATCTGGGCGCTTGGCGACTGCAATGGCCGGGGCGCTTTCACACATACGTCCTAC
AACGACTACGAGATCGTCGCGGCCAATCTGCTCGATAACGATCCGCGCGCGGTGACGGATCGCATCCCGGCCTATGCCTT
GTTTACCGACCCGCCGTTGGGCCGCATCGGCATGACGGAGCGGGAAGCGCGGCAGTCAGGGCGCAAGGTGCTGGTTGGCA
CGCGGCCCATGAGCCGTGTCGGGCGGGCCGTGGAGAAGGGCGAAAGCCAGGGCTTTATGAAGATACTCGTCGACGCTGAC
ACGCGGCTGTTGCTGGGCGCTGCGATCCTCGGCCTGAACGGCGACGAGGTGGTGCACTCACTGCTCGACGTCATGTACGC
CGGGGCTCCCTACACGACCATCAGCCGCGCGGTGCATATCCACCCCACGGTGTCCGAACTGGTGCCGACGGTGTTGCAGG
GATTGCGGGCGCTGACCTAG

Upstream 100 bases:

>100_bases
CAGGCGCGGTCCTGGCGCTGGCGGCCCGGGTGATGTCGCGGACGCGCCCATTTTCGTGGCTCGCCCGGTGGCGAGCACGG
TACCCGCAAGGAGAATCGTG

Downstream 100 bases:

>100_bases
CGTTGCCCTGGTGCCGCCGTCGGGATTAGGGATGGATCTTCTCCCCCTTGTTCAGCATCTCGATGAACTGGGCAATCTTT
CTGGCGCGTGTTTCAGCTTT

Product: mercuric reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MAQRFDAIIIGTGQAGPALAARLAGAGMKLAVIERGRFGGTCVNTGCIPTKALIASAYAAQLARRAAEYGVTIGGPVAVD
MRQVKARKDEISGRSSQGVEQWMRGLDNVTVHQGHARFEHARGVRVNGELLEADQIFINVGGRALIPPMPGLDQVSYLTN
SSMMEVDFLPEHLIIVGGSYIGLEFGQMYRRFGARVTIVEKGPRLIQREDEDVSQAVREILEREGIEVRLDANCLSARKD
GDHIAVGLDCAGGAPEVHGSHLLMAVGRVPNTDDLGLDKAGIETDARGYIKVDDQLRTSVPGIWALGDCNGRGAFTHTSY
NDYEIVAANLLDNDPRAVTDRIPAYALFTDPPLGRIGMTEREARQSGRKVLVGTRPMSRVGRAVEKGESQGFMKILVDAD
TRLLLGAAILGLNGDEVVHSLLDVMYAGAPYTTISRAVHIHPTVSELVPTVLQGLRALT

Sequences:

>Translated_459_residues
MAQRFDAIIIGTGQAGPALAARLAGAGMKLAVIERGRFGGTCVNTGCIPTKALIASAYAAQLARRAAEYGVTIGGPVAVD
MRQVKARKDEISGRSSQGVEQWMRGLDNVTVHQGHARFEHARGVRVNGELLEADQIFINVGGRALIPPMPGLDQVSYLTN
SSMMEVDFLPEHLIIVGGSYIGLEFGQMYRRFGARVTIVEKGPRLIQREDEDVSQAVREILEREGIEVRLDANCLSARKD
GDHIAVGLDCAGGAPEVHGSHLLMAVGRVPNTDDLGLDKAGIETDARGYIKVDDQLRTSVPGIWALGDCNGRGAFTHTSY
NDYEIVAANLLDNDPRAVTDRIPAYALFTDPPLGRIGMTEREARQSGRKVLVGTRPMSRVGRAVEKGESQGFMKILVDAD
TRLLLGAAILGLNGDEVVHSLLDVMYAGAPYTTISRAVHIHPTVSELVPTVLQGLRALT
>Mature_458_residues
AQRFDAIIIGTGQAGPALAARLAGAGMKLAVIERGRFGGTCVNTGCIPTKALIASAYAAQLARRAAEYGVTIGGPVAVDM
RQVKARKDEISGRSSQGVEQWMRGLDNVTVHQGHARFEHARGVRVNGELLEADQIFINVGGRALIPPMPGLDQVSYLTNS
SMMEVDFLPEHLIIVGGSYIGLEFGQMYRRFGARVTIVEKGPRLIQREDEDVSQAVREILEREGIEVRLDANCLSARKDG
DHIAVGLDCAGGAPEVHGSHLLMAVGRVPNTDDLGLDKAGIETDARGYIKVDDQLRTSVPGIWALGDCNGRGAFTHTSYN
DYEIVAANLLDNDPRAVTDRIPAYALFTDPPLGRIGMTEREARQSGRKVLVGTRPMSRVGRAVEKGESQGFMKILVDADT
RLLLGAAILGLNGDEVVHSLLDVMYAGAPYTTISRAVHIHPTVSELVPTVLQGLRALT

Specific function: Unknown

COG id: COG1249

COG function: function code C; Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI91199540, Length=461, Percent_Identity=29.0672451193059, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI50301238, Length=466, Percent_Identity=28.9699570815451, Blast_Score=171, Evalue=9e-43,
Organism=Homo sapiens, GI22035672, Length=458, Percent_Identity=29.0393013100437, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI33519430, Length=437, Percent_Identity=22.6544622425629, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI33519428, Length=437, Percent_Identity=22.6544622425629, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI33519426, Length=437, Percent_Identity=22.6544622425629, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI148277065, Length=437, Percent_Identity=22.6544622425629, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI148277071, Length=437, Percent_Identity=22.6544622425629, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI291045266, Length=435, Percent_Identity=23.9080459770115, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI291045268, Length=428, Percent_Identity=24.0654205607477, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI87081717, Length=453, Percent_Identity=35.3200883002208, Blast_Score=251, Evalue=5e-68,
Organism=Escherichia coli, GI1786307, Length=455, Percent_Identity=30.1098901098901, Blast_Score=221, Evalue=6e-59,
Organism=Escherichia coli, GI1789915, Length=454, Percent_Identity=30.1762114537445, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI87082354, Length=459, Percent_Identity=26.797385620915, Blast_Score=142, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI32565766, Length=456, Percent_Identity=28.0701754385965, Blast_Score=177, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI71983429, Length=462, Percent_Identity=28.1385281385281, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI71983419, Length=461, Percent_Identity=27.5488069414317, Blast_Score=145, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI17557007, Length=474, Percent_Identity=25.5274261603376, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI71982272, Length=481, Percent_Identity=23.2848232848233, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17559934, Length=187, Percent_Identity=28.8770053475936, Blast_Score=75, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6321091, Length=466, Percent_Identity=29.8283261802575, Blast_Score=211, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6325166, Length=477, Percent_Identity=25.3668763102725, Blast_Score=135, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6325240, Length=476, Percent_Identity=25, Blast_Score=117, Evalue=3e-27,
Organism=Drosophila melanogaster, GI21358499, Length=454, Percent_Identity=28.8546255506608, Blast_Score=199, Evalue=4e-51,
Organism=Drosophila melanogaster, GI24640549, Length=473, Percent_Identity=26.4270613107822, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24640553, Length=473, Percent_Identity=26.4270613107822, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24640551, Length=473, Percent_Identity=26.4270613107822, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI17737741, Length=480, Percent_Identity=22.9166666666667, Blast_Score=86, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR012999
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: NA

Molecular weight: Translated: 49334; Mature: 49203

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS00076 PYRIDINE_REDOX_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQRFDAIIIGTGQAGPALAARLAGAGMKLAVIERGRFGGTCVNTGCIPTKALIASAYAA
CCCCCCEEEEECCCCCHHHHHHHHCCCEEEEEEECCCCCCEEEECCCCCHHHHHHHHHHH
QLARRAAEYGVTIGGPVAVDMRQVKARKDEISGRSSQGVEQWMRGLDNVTVHQGHARFEH
HHHHHHHHCCCEECCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEECCCHHHHH
ARGVRVNGELLEADQIFINVGGRALIPPMPGLDQVSYLTNSSMMEVDFLPEHLIIVGGSY
CCCEEECCCEEECCEEEEEECCEEECCCCCCCCHHHHHCCCCEEEEECCCCEEEEECCCE
IGLEFGQMYRRFGARVTIVEKGPRLIQREDEDVSQAVREILEREGIEVRLDANCLSARKD
EHHHHHHHHHHHCCEEEEEECCCHHHCCCCHHHHHHHHHHHHHCCCEEEECCHHHCCCCC
GDHIAVGLDCAGGAPEVHGSHLLMAVGRVPNTDDLGLDKAGIETDARGYIKVDDQLRTSV
CCEEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHCC
PGIWALGDCNGRGAFTHTSYNDYEIVAANLLDNDPRAVTDRIPAYALFTDPPLGRIGMTE
CCEEEEECCCCCCCEEECCCCCEEEEEEECCCCCCHHHHHCCCEEEEECCCCCCCCCCCH
REARQSGRKVLVGTRPMSRVGRAVEKGESQGFMKILVDADTRLLLGAAILGLNGDEVVHS
HHHHHCCCEEEEECCCHHHHHHHHHCCCCCCEEEEEECCCCHHEEHHHHCCCCHHHHHHH
LLDVMYAGAPYTTISRAVHIHPTVSELVPTVLQGLRALT
HHHHHHCCCCCHHHCCEEEECCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AQRFDAIIIGTGQAGPALAARLAGAGMKLAVIERGRFGGTCVNTGCIPTKALIASAYAA
CCCCCEEEEECCCCCHHHHHHHHCCCEEEEEEECCCCCCEEEECCCCCHHHHHHHHHHH
QLARRAAEYGVTIGGPVAVDMRQVKARKDEISGRSSQGVEQWMRGLDNVTVHQGHARFEH
HHHHHHHHCCCEECCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEECCCHHHHH
ARGVRVNGELLEADQIFINVGGRALIPPMPGLDQVSYLTNSSMMEVDFLPEHLIIVGGSY
CCCEEECCCEEECCEEEEEECCEEECCCCCCCCHHHHHCCCCEEEEECCCCEEEEECCCE
IGLEFGQMYRRFGARVTIVEKGPRLIQREDEDVSQAVREILEREGIEVRLDANCLSARKD
EHHHHHHHHHHHCCEEEEEECCCHHHCCCCHHHHHHHHHHHHHCCCEEEECCHHHCCCCC
GDHIAVGLDCAGGAPEVHGSHLLMAVGRVPNTDDLGLDKAGIETDARGYIKVDDQLRTSV
CCEEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHCC
PGIWALGDCNGRGAFTHTSYNDYEIVAANLLDNDPRAVTDRIPAYALFTDPPLGRIGMTE
CCEEEEECCCCCCCEEECCCCCEEEEEEECCCCCCHHHHHCCCEEEEECCCCCCCCCCCH
REARQSGRKVLVGTRPMSRVGRAVEKGESQGFMKILVDADTRLLLGAAILGLNGDEVVHS
HHHHHCCCEEEEECCCHHHHHHHHHCCCCCCEEEEEECCCCHHEEHHHHCCCCHHHHHHH
LLDVMYAGAPYTTISRAVHIHPTVSELVPTVLQGLRALT
HHHHHHCCCCCHHHCCEEEECCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FAD. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]