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The map label for this gene is degU [H]

Identifier: 94313908

GI number: 94313908

Start: 1661622

End: 1662335

Strand: Direct

Name: degU [H]

Synonym: Rmet_4986

Alternate gene names: 94313908

Gene position: 1661622-1662335 (Clockwise)

Preceding gene: 94313906

Following gene: 94313909

Centisome position: 64.4

GC content: 65.55

Gene sequence:

>714_bases
ATGACCCACCAGCCCCCGGCGATGGACGCGGATATCCGCGTGATGCTTGTAGAAGACGACCCGGCCACCAGTGCCCGCCT
GACTTCCGCGCTTGCCAGCGTGCCCGGCATCCATGTGATGGCGACCTGCCAGAACCGCGTCAGCGCCTGCGAGTGGCTGA
CCGTCAATACGCCCGATGTGGTGCTGTGCGACCTGGGCCTGCCCGATGGCTCCGGCATCGACGTGATCCGCTTTGCCCGG
CGCCGGCACCCACACTGCGAGTGCATGGTCATCACCATGTTCGGTGATGAGGCCAATGTGCTGGCCAGCATCTCGGCCGG
GGCCACCGGCTATCTGCTCAAGGACGCTTCCGACGAAGACCTGCGTGCCTCTGTGCGCGAGCTTCGCGCAGGCGGCTCTC
CGATGAGTCCCGTGATCGCCCGCCGCGTCATTAACCGGTTGCGCGATGCGAACATCCCTGCCCCGCGCGCCGTCCGTGCG
GAACCGGCGACGCCGTTGTTACCAGAGGCCGTTGTTGCGCTCTCCGCGCGGGAGTCCGAGATTCTCGACCTCGTCGCGCG
CGGCTACACGTATGCGGAGATCGCCCGGCACCTGTCCATCAGCGTGAATACGGTGGCGGCCCACATCCGCAACATCTACG
GCAAGTTGGCCGTGAACTCGCGCTCCGAGGCGGTTTTCGAAGCCCACAAGCTTGGTCTGCTGAAATCGATGTGA

Upstream 100 bases:

>100_bases
GCCGTCGCTAGGATAGCCCGGCGCCAGCCCTTGCCTGGCCGGCGCGGCAAACGGCGCGGCAGGCCGGACTGCGCAACCGA
AGTGGCCGATCGACCAGACC

Downstream 100 bases:

>100_bases
GCCGCACGGTGATCGCGCGCCTCACTCCCGCCCCGCGCTCCCAGCGCTCCTCGCGATGGATCGCCCTGCTGCTCGGCTTC
GTCACCCTGGCCGCGCTGAT

Product: LuxR family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MTHQPPAMDADIRVMLVEDDPATSARLTSALASVPGIHVMATCQNRVSACEWLTVNTPDVVLCDLGLPDGSGIDVIRFAR
RRHPHCECMVITMFGDEANVLASISAGATGYLLKDASDEDLRASVRELRAGGSPMSPVIARRVINRLRDANIPAPRAVRA
EPATPLLPEAVVALSARESEILDLVARGYTYAEIARHLSISVNTVAAHIRNIYGKLAVNSRSEAVFEAHKLGLLKSM

Sequences:

>Translated_237_residues
MTHQPPAMDADIRVMLVEDDPATSARLTSALASVPGIHVMATCQNRVSACEWLTVNTPDVVLCDLGLPDGSGIDVIRFAR
RRHPHCECMVITMFGDEANVLASISAGATGYLLKDASDEDLRASVRELRAGGSPMSPVIARRVINRLRDANIPAPRAVRA
EPATPLLPEAVVALSARESEILDLVARGYTYAEIARHLSISVNTVAAHIRNIYGKLAVNSRSEAVFEAHKLGLLKSM
>Mature_236_residues
THQPPAMDADIRVMLVEDDPATSARLTSALASVPGIHVMATCQNRVSACEWLTVNTPDVVLCDLGLPDGSGIDVIRFARR
RHPHCECMVITMFGDEANVLASISAGATGYLLKDASDEDLRASVRELRAGGSPMSPVIARRVINRLRDANIPAPRAVRAE
PATPLLPEAVVALSARESEILDLVARGYTYAEIARHLSISVNTVAAHIRNIYGKLAVNSRSEAVFEAHKLGLLKSM

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=210, Percent_Identity=32.8571428571429, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1788222, Length=223, Percent_Identity=24.6636771300448, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1787473, Length=234, Percent_Identity=28.2051282051282, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788546, Length=213, Percent_Identity=23.0046948356808, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 25513; Mature: 25381

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHQPPAMDADIRVMLVEDDPATSARLTSALASVPGIHVMATCQNRVSACEWLTVNTPDV
CCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHEEEEEECCCCE
VLCDLGLPDGSGIDVIRFARRRHPHCECMVITMFGDEANVLASISAGATGYLLKDASDED
EEEECCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEECCCCCEEEEECCCCHH
LRASVRELRAGGSPMSPVIARRVINRLRDANIPAPRAVRAEPATPLLPEAVVALSARESE
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHH
ILDLVARGYTYAEIARHLSISVNTVAAHIRNIYGKLAVNSRSEAVFEAHKLGLLKSM
HHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
THQPPAMDADIRVMLVEDDPATSARLTSALASVPGIHVMATCQNRVSACEWLTVNTPDV
CCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHEEEEEECCCCE
VLCDLGLPDGSGIDVIRFARRRHPHCECMVITMFGDEANVLASISAGATGYLLKDASDED
EEEECCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEECCCCCEEEEECCCCHH
LRASVRELRAGGSPMSPVIARRVINRLRDANIPAPRAVRAEPATPLLPEAVVALSARESE
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHH
ILDLVARGYTYAEIARHLSISVNTVAAHIRNIYGKLAVNSRSEAVFEAHKLGLLKSM
HHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]