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The map label for this gene is hipA [C]

Identifier: 94313823

GI number: 94313823

Start: 1564010

End: 1565311

Strand: Direct

Name: hipA [C]

Synonym: Rmet_4901

Alternate gene names: 94313823

Gene position: 1564010-1565311 (Clockwise)

Preceding gene: 94313822

Following gene: 94313825

Centisome position: 60.62

GC content: 64.52

Gene sequence:

>1302_bases
ATGACCACGTCGATCCGCTACCTGCGCCTGTTTCTCTATACGGCTACCGGGCGCCGTGGCATCGGCTACCTGTCCCAGTA
TGGCGACATCCTCCGGATCTCTTTCGACCGTGATTACATCGAGGACGAGAATCGCCCCACGTTGTCGCTCGGATACGTCG
GCGAGACAGAGGCGGCTACGCGGGCGATCCTCACGGCGCTACGGGACGTACGAGTGGTCCGCACGGACGGTCACTGGCCG
GTGTTCTTCCAGAACCTCCTGCCGGAGGGCCACAATCGCGAGCGCCTGGCCAGCGAGCGCGGCTGCAGCACGGAAGACGA
GTTCGAACTGCTGGCGGCGGCCGGTCACGACTTGCCGGGCGCGGTGGAAGTCGAACCCGTTCCGCCCGCCGAAGGCGTGC
CCCAGATCGTGCGCAATTGGCACACCGCGCTAGGGCTCGATGTGCTGGAGCCCGGCTTCGTCGAAGACCCGGTGGAAGAC
GCCGCGGCCATCCCCGGCGTGGTCACGAAATTCTCGGCCATCCAGCAGGGACGGCGTTACGTGGTCAAGCGCCACGGCGA
GGCTGGCGACTTCATCCTCAAACTGCCATCGACGCGCCATCCCGATCTGGTCGAGAACGAATTCACGGGTTACCAGCTAT
GCAGGGCCCTAGGGCTCGATTGCGCAGAGGCAACAGTCATCTCGCGCGAGGAAGCCGAGCTACCCGAGCAGGTGCCCTTC
CAGCGCATTCTGGCCGTCAAACGCTTCGATCGCGCCCCTGGCGGGCATCGCGTGCACATGGAGGAGTTCGCGCAGATACT
CGGGTACGCACCGCGAAACAAGTACGGTCGCGCGCTCGCGCTCGACTACGGCAATATGCTTCGCGTACTCGATCGACTTT
CGGCGCGCCCCGCGCCCGACGTCCAGGAGTTCATCAAGCGTTTCGTTGCATTCCTGCTGATGGGCAACACCGATGCCCAT
TTGAAAAATTGGGCAGTTCGCTATCCGGATGGCCGGGCGCCTGTCCTCTCGCCGCTCTACGACCCCGTATGCGTGACGGC
GTTTTTCGACGACGTTCCCGTGACGGACTACGGCATCAATCGCGCGATCGACAAGACCTTGCGCGCCTATACGTTCGACG
ACCTCGACGCCATGGTGCGCTCCGCCGGCCTGCTCAGGCGCGCGCGTTTGCTGTCGATCGCGAGGGAGACGGTGCGTCAG
GCTCAAGCCGATTGGCCACGCATTCTGGAGGATGCGCCCGAAGGTGTCCGCCGAGCCGTGTCGGAGCGTCTCGCCGGTGG
TGTGGCACTGACCCGAACCTGA

Upstream 100 bases:

>100_bases
GGCCAGATCTCGAGAATTTCGTTCGCGCCGGAGGCAAGTATCTCGCCCAACCTCCGGGCGGCGATGCCCCACCGTCGGTC
GTCGACACCTTGATCGCGAA

Downstream 100 bases:

>100_bases
CGCCAAGTGCGCCAAGTGCGCCAAACGCCGATACAGTGCGCCGTACCTGGATCAAGCCGTAGCGCCGCCGTCGAGCCCGA
TCGTCTGCCCGGAGATATAG

Product: putative regulator containing a HipA-like domain

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MTTSIRYLRLFLYTATGRRGIGYLSQYGDILRISFDRDYIEDENRPTLSLGYVGETEAATRAILTALRDVRVVRTDGHWP
VFFQNLLPEGHNRERLASERGCSTEDEFELLAAAGHDLPGAVEVEPVPPAEGVPQIVRNWHTALGLDVLEPGFVEDPVED
AAAIPGVVTKFSAIQQGRRYVVKRHGEAGDFILKLPSTRHPDLVENEFTGYQLCRALGLDCAEATVISREEAELPEQVPF
QRILAVKRFDRAPGGHRVHMEEFAQILGYAPRNKYGRALALDYGNMLRVLDRLSARPAPDVQEFIKRFVAFLLMGNTDAH
LKNWAVRYPDGRAPVLSPLYDPVCVTAFFDDVPVTDYGINRAIDKTLRAYTFDDLDAMVRSAGLLRRARLLSIARETVRQ
AQADWPRILEDAPEGVRRAVSERLAGGVALTRT

Sequences:

>Translated_433_residues
MTTSIRYLRLFLYTATGRRGIGYLSQYGDILRISFDRDYIEDENRPTLSLGYVGETEAATRAILTALRDVRVVRTDGHWP
VFFQNLLPEGHNRERLASERGCSTEDEFELLAAAGHDLPGAVEVEPVPPAEGVPQIVRNWHTALGLDVLEPGFVEDPVED
AAAIPGVVTKFSAIQQGRRYVVKRHGEAGDFILKLPSTRHPDLVENEFTGYQLCRALGLDCAEATVISREEAELPEQVPF
QRILAVKRFDRAPGGHRVHMEEFAQILGYAPRNKYGRALALDYGNMLRVLDRLSARPAPDVQEFIKRFVAFLLMGNTDAH
LKNWAVRYPDGRAPVLSPLYDPVCVTAFFDDVPVTDYGINRAIDKTLRAYTFDDLDAMVRSAGLLRRARLLSIARETVRQ
AQADWPRILEDAPEGVRRAVSERLAGGVALTRT
>Mature_432_residues
TTSIRYLRLFLYTATGRRGIGYLSQYGDILRISFDRDYIEDENRPTLSLGYVGETEAATRAILTALRDVRVVRTDGHWPV
FFQNLLPEGHNRERLASERGCSTEDEFELLAAAGHDLPGAVEVEPVPPAEGVPQIVRNWHTALGLDVLEPGFVEDPVEDA
AAIPGVVTKFSAIQQGRRYVVKRHGEAGDFILKLPSTRHPDLVENEFTGYQLCRALGLDCAEATVISREEAELPEQVPFQ
RILAVKRFDRAPGGHRVHMEEFAQILGYAPRNKYGRALALDYGNMLRVLDRLSARPAPDVQEFIKRFVAFLLMGNTDAHL
KNWAVRYPDGRAPVLSPLYDPVCVTAFFDDVPVTDYGINRAIDKTLRAYTFDDLDAMVRSAGLLRRARLLSIARETVRQA
QADWPRILEDAPEGVRRAVSERLAGGVALTRT

Specific function: Unbalanced Or Excessive Expression Of Hipa Is Toxic To The Cell. [C]

COG id: COG3550

COG function: function code R; Uncharacterized protein related to capsule biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli hipA, H.influenzae HI_0665 and y4mE [H]

Homologues:

Organism=Escherichia coli, GI1787785, Length=296, Percent_Identity=27.027027027027, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012893
- InterPro:   IPR012894
- InterPro:   IPR017508 [H]

Pfam domain/function: PF07804 HipA_C; PF07805 HipA_N [H]

EC number: NA

Molecular weight: Translated: 48483; Mature: 48352

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSIRYLRLFLYTATGRRGIGYLSQYGDILRISFDRDYIEDENRPTLSLGYVGETEAAT
CCCHHHHHHHHHHHCCCCCCCHHHHHCCCEEEEEECCHHHCCCCCCEEEECCCCCHHHHH
RAILTALRDVRVVRTDGHWPVFFQNLLPEGHNRERLASERGCSTEDEFELLAAAGHDLPG
HHHHHHHHHCEEEEECCCCHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHCCCCCCC
AVEVEPVPPAEGVPQIVRNWHTALGLDVLEPGFVEDPVEDAAAIPGVVTKFSAIQQGRRY
CEEECCCCCCCCHHHHHHHHHHHHCCHHCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHH
VVKRHGEAGDFILKLPSTRHPDLVENEFTGYQLCRALGLDCAEATVISREEAELPEQVPF
HHHHCCCCCCEEEECCCCCCCCCHHCCCHHHHHHHHHCCCHHHHHHHCCHHHCCCHHCCH
QRILAVKRFDRAPGGHRVHMEEFAQILGYAPRNKYGRALALDYGNMLRVLDRLSARPAPD
HHHHHHHHHHCCCCCCEECHHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHHCCCCCCC
VQEFIKRFVAFLLMGNTDAHLKNWAVRYPDGRAPVLSPLYDPVCVTAFFDDVPVTDYGIN
HHHHHHHHHHHHHCCCCCHHHHCCEEECCCCCCCCHHHCCCHHHHHHHHCCCCCCCCCHH
RAIDKTLRAYTFDDLDAMVRSAGLLRRARLLSIARETVRQAQADWPRILEDAPEGVRRAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHHHH
SERLAGGVALTRT
HHHHHCCEEECCC
>Mature Secondary Structure 
TTSIRYLRLFLYTATGRRGIGYLSQYGDILRISFDRDYIEDENRPTLSLGYVGETEAAT
CCHHHHHHHHHHHCCCCCCCHHHHHCCCEEEEEECCHHHCCCCCCEEEECCCCCHHHHH
RAILTALRDVRVVRTDGHWPVFFQNLLPEGHNRERLASERGCSTEDEFELLAAAGHDLPG
HHHHHHHHHCEEEEECCCCHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHCCCCCCC
AVEVEPVPPAEGVPQIVRNWHTALGLDVLEPGFVEDPVEDAAAIPGVVTKFSAIQQGRRY
CEEECCCCCCCCHHHHHHHHHHHHCCHHCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHH
VVKRHGEAGDFILKLPSTRHPDLVENEFTGYQLCRALGLDCAEATVISREEAELPEQVPF
HHHHCCCCCCEEEECCCCCCCCCHHCCCHHHHHHHHHCCCHHHHHHHCCHHHCCCHHCCH
QRILAVKRFDRAPGGHRVHMEEFAQILGYAPRNKYGRALALDYGNMLRVLDRLSARPAPD
HHHHHHHHHHCCCCCCEECHHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHHCCCCCCC
VQEFIKRFVAFLLMGNTDAHLKNWAVRYPDGRAPVLSPLYDPVCVTAFFDDVPVTDYGIN
HHHHHHHHHHHHHCCCCCHHHHCCEEECCCCCCCCHHHCCCHHHHHHHHCCCCCCCCCHH
RAIDKTLRAYTFDDLDAMVRSAGLLRRARLLSIARETVRQAQADWPRILEDAPEGVRRAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHHHH
SERLAGGVALTRT
HHHHHCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]