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The map label for this gene is catM [H]

Identifier: 94313802

GI number: 94313802

Start: 1541962

End: 1542879

Strand: Reverse

Name: catM [H]

Synonym: Rmet_4880

Alternate gene names: 94313802

Gene position: 1542879-1541962 (Counterclockwise)

Preceding gene: 94313808

Following gene: 94313800

Centisome position: 59.8

GC content: 62.75

Gene sequence:

>918_bases
TTGGAATTGAGACATTTGAGGTACTTCGTGGCCGTGGCCGAGGAGCGCAACTTCACGCGCGCCGCGGAACGGCTGCATAT
CGCGCAGCCTCCGCTGTCGCGCCAGATCCAGCAACTGGAGGAGTCGCTGGGTGTGTTGCTGTTCGAGCGCAACTCCCGGC
CACTCAAGCTGACCGACACCGGGCGCTTCTTCTACACCCACGCCTTGCAACTGCTGGCGCAGACCACCGAACTTGAGGCG
ATGATGCGCCGGGTTGGCAAGATTGAGCGGGCGATGTCGATCGGCTTCGTGGGCTCCACGCTCTACGGCATGTTGCCGCG
CATCATCCGCCGCTTCCGGACCGAACACGCCGAGATCGAACTGACGCTGCACGAGATGTCGACGATGGACCAGATCAAGG
CACTCAAGGAAGGGCGCATCGATGTGGGTTTTGGCCGCATCCGGCACGAAGACCCGGCCGTCCGCCGCGTGGTGCTGCGC
GAGGAACGCATGATCGTGGCTCTGCCGGTGGGGCATCCGCTGTCGATCGGCAGGAAGATGCTGGCGTTGCCGGATCTGCT
CGAAGACACGCTGATCATCTTCCCGAAGGCGCCACGCCCGAGTTTTGCCGATCAGGTGCTGGCGGCGTTTCACGACCGCG
CGTTGCGCCCGGGCCGCATCCACGAGGTACGCGAGTTGCAGATCGCGCTGGGGTTGGTGGCGATGGGCGAGGGTATCTCA
GTGGTACCCAGCAGCGTCTACGGCCTCAAGCGTGACGATGTGACCTACGTTGAGCTTGATGATGCGAAGCTGGTGTCGCC
GATCATCATGAGCATGCGCACACTGGACGAATCCGAGGACCTGCGTGCGATGCTGGACATGATCTACCGGCTCTACGAGG
AAATCGGCATGGAGTACATTCCGCCGGCCCAGGAGTGA

Upstream 100 bases:

>100_bases
ATCGAGGATTGCCGTCCGACTTGTTGCGGAGCATAGTTCAGGGGTGTTTGGGCAGTCCAAGACTGATTGAGTATCCGGAC
GATACCTGTGAGGTATAGCG

Downstream 100 bases:

>100_bases
CTACGCTTGCTGCAGGACCCATGCGACCGCGCGGGCCAGGTATGGCGAGGTGTCGCCAGAGCGGTAGCTCATGATCACGG
GTGAGACGAAGCCCGGAGCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Ben and cat operon transcriptional regulator [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MELRHLRYFVAVAEERNFTRAAERLHIAQPPLSRQIQQLEESLGVLLFERNSRPLKLTDTGRFFYTHALQLLAQTTELEA
MMRRVGKIERAMSIGFVGSTLYGMLPRIIRRFRTEHAEIELTLHEMSTMDQIKALKEGRIDVGFGRIRHEDPAVRRVVLR
EERMIVALPVGHPLSIGRKMLALPDLLEDTLIIFPKAPRPSFADQVLAAFHDRALRPGRIHEVRELQIALGLVAMGEGIS
VVPSSVYGLKRDDVTYVELDDAKLVSPIIMSMRTLDESEDLRAMLDMIYRLYEEIGMEYIPPAQE

Sequences:

>Translated_305_residues
MELRHLRYFVAVAEERNFTRAAERLHIAQPPLSRQIQQLEESLGVLLFERNSRPLKLTDTGRFFYTHALQLLAQTTELEA
MMRRVGKIERAMSIGFVGSTLYGMLPRIIRRFRTEHAEIELTLHEMSTMDQIKALKEGRIDVGFGRIRHEDPAVRRVVLR
EERMIVALPVGHPLSIGRKMLALPDLLEDTLIIFPKAPRPSFADQVLAAFHDRALRPGRIHEVRELQIALGLVAMGEGIS
VVPSSVYGLKRDDVTYVELDDAKLVSPIIMSMRTLDESEDLRAMLDMIYRLYEEIGMEYIPPAQE
>Mature_305_residues
MELRHLRYFVAVAEERNFTRAAERLHIAQPPLSRQIQQLEESLGVLLFERNSRPLKLTDTGRFFYTHALQLLAQTTELEA
MMRRVGKIERAMSIGFVGSTLYGMLPRIIRRFRTEHAEIELTLHEMSTMDQIKALKEGRIDVGFGRIRHEDPAVRRVVLR
EERMIVALPVGHPLSIGRKMLALPDLLEDTLIIFPKAPRPSFADQVLAAFHDRALRPGRIHEVRELQIALGLVAMGEGIS
VVPSSVYGLKRDDVTYVELDDAKLVSPIIMSMRTLDESEDLRAMLDMIYRLYEEIGMEYIPPAQE

Specific function: Positive regulator of the ben and cat genes for benzoate degradation. BenM is necessary for ben gene expression but not for expression of the cat genes, which can be regulated by CatM. Binds to the inducers cis,cis-muconate and benzoate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788887, Length=256, Percent_Identity=33.984375, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1787879, Length=268, Percent_Identity=33.2089552238806, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI2367136, Length=257, Percent_Identity=31.9066147859922, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790399, Length=260, Percent_Identity=30, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI145693105, Length=279, Percent_Identity=27.9569892473118, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87081904, Length=264, Percent_Identity=29.9242424242424, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI157672245, Length=192, Percent_Identity=32.8125, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787601, Length=247, Percent_Identity=27.1255060728745, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788297, Length=250, Percent_Identity=29.2, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787806, Length=251, Percent_Identity=28.6852589641434, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790208, Length=146, Percent_Identity=34.9315068493151, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1788481, Length=179, Percent_Identity=29.608938547486, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788748, Length=147, Percent_Identity=27.891156462585, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789173, Length=193, Percent_Identity=30.5699481865285, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790783, Length=146, Percent_Identity=29.4520547945205, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787530, Length=253, Percent_Identity=23.3201581027668, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI87082132, Length=178, Percent_Identity=30.3370786516854, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI145693193, Length=135, Percent_Identity=33.3333333333333, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34953; Mature: 34953

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRHLRYFVAVAEERNFTRAAERLHIAQPPLSRQIQQLEESLGVLLFERNSRPLKLTDT
CCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCEEEECCCCCCEEEECC
GRFFYTHALQLLAQTTELEAMMRRVGKIERAMSIGFVGSTLYGMLPRIIRRFRTEHAEIE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
LTLHEMSTMDQIKALKEGRIDVGFGRIRHEDPAVRRVVLREERMIVALPVGHPLSIGRKM
EEHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHH
LALPDLLEDTLIIFPKAPRPSFADQVLAAFHDRALRPGRIHEVRELQIALGLVAMGEGIS
HHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCE
VVPSSVYGLKRDDVTYVELDDAKLVSPIIMSMRTLDESEDLRAMLDMIYRLYEEIGMEYI
ECCHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC
PPAQE
CCCCC
>Mature Secondary Structure
MELRHLRYFVAVAEERNFTRAAERLHIAQPPLSRQIQQLEESLGVLLFERNSRPLKLTDT
CCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCEEEECCCCCCEEEECC
GRFFYTHALQLLAQTTELEAMMRRVGKIERAMSIGFVGSTLYGMLPRIIRRFRTEHAEIE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
LTLHEMSTMDQIKALKEGRIDVGFGRIRHEDPAVRRVVLREERMIVALPVGHPLSIGRKM
EEHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHH
LALPDLLEDTLIIFPKAPRPSFADQVLAAFHDRALRPGRIHEVRELQIALGLVAMGEGIS
HHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCE
VVPSSVYGLKRDDVTYVELDDAKLVSPIIMSMRTLDESEDLRAMLDMIYRLYEEIGMEYI
ECCHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC
PPAQE
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9573203 [H]