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The map label for this gene is namA [H]

Identifier: 94313781

GI number: 94313781

Start: 1517387

End: 1518502

Strand: Reverse

Name: namA [H]

Synonym: Rmet_4859

Alternate gene names: 94313781

Gene position: 1518502-1517387 (Counterclockwise)

Preceding gene: 94313782

Following gene: 94313779

Centisome position: 58.85

GC content: 65.23

Gene sequence:

>1116_bases
ATGCCTCATCTCTTCGATCCGTACCGGATCGGCAATCTCGAGCTTGCCAACCGCATCGCCATCGCGCCGATGTGCCAGTA
CTCGGCACAGGAAGGCAATGCCACCGACTGGCACATGATTCACCTGGGCCAGATGGCGCTGTCCGGAGCGGGCCTGCTCA
TCATCGAAGCCACCGCGGTTTCGCCTGAAGGCCGCATCACGCCGACCGACCTTGGCCTGTACAACGATGCCAACGAAGCT
GCGCTGGGCCGTGTGCTTGGCGCCGTGCGCAACCATTCGCCCATCGCGGTGACCATCCAGCTTGCCCATGCTGGCCGCAA
GGCATCGAGCGAAGCGCCGTGGGATGGCGGCGGCCAGATTCGACCCGACCAGCCGCGAGGCTGGCAGACCTTTGCGCCGT
CGGCAGTGCCGCATGCGGCGGGAGAAGTCCCGCCGGCCGCGCTCGACAAGGCCGGTATGAAGAAGATTCGCGACGACTTC
GTCGCGGCTGCCAAGCGCGCGGCTCGCCTGGGTATCGAAGGCATCGAAGTGCATGGCGCTCACGGCTATCTGCTGCACCA
GTTTCTTTCGCCCATCGCCAATCACCGTACGGACGAATACGGTGGCAGCCTCGAGAACCGGATGCGCTTCCCGCTGGAAG
TGTTCGACGCCGTGCGAGAGGCGTTTCCTGCGGAACGTCCGGTCTGGATGCGCGTTTCCGCCACCGACTGGGTGCCGAAT
GGATGGGACATCGAGGGGACGATCGCGCTATCGCACGAACTGAAGGCGCGTGGCAGTGCGGCGGTGCATGTGAGCACGGG
CGGCGTGTCGCCGCAGCAGGCCATCAAGATTGGCCCGGGATACCAGGTGCCTTACGCGCAACGCGTCAAGGCGGAGGTGG
GGTTGCCGACGATGGCGGTCGGGCTGATCACCGAAGCCGAACAGGCCGAAGCGATCATCGCCAACAATGAGGCGGACATT
ATCTCGATCGCCCGCGCCATGCTGTACGACCCGCGCTGGCCGTGGCACGCGGCGGCCAAGCTTGGCGCTAGTGTCAACGC
GCCGAAGCAGTATTGGCGCTCGCAGCCGCGCGGGCTGGAAAAGCTGTTCAAGGACGCGCACTTCGGCCAGCGTTGA

Upstream 100 bases:

>100_bases
GGCGGCCAGGACCGTATCCCATGCCGCCGGCAGGGTCAGCAGGGTTTTTCAGCGGCGACTACAATCGCCCGGACCAGAAC
ACCCCGCAAGGATGGCCCTC

Downstream 100 bases:

>100_bases
TGGGCGGTCCTTGAGCCGACGGCCTTTGAGTGGGCGGCCTTTGAGCAGCTGGCAGGGAACGTAAAAGCGGGAAGGCAGAT
ACTGCCTTCCCGCTTTGTTC

Product: putative NADH-depentdent flavin oxidoreductase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MPHLFDPYRIGNLELANRIAIAPMCQYSAQEGNATDWHMIHLGQMALSGAGLLIIEATAVSPEGRITPTDLGLYNDANEA
ALGRVLGAVRNHSPIAVTIQLAHAGRKASSEAPWDGGGQIRPDQPRGWQTFAPSAVPHAAGEVPPAALDKAGMKKIRDDF
VAAAKRAARLGIEGIEVHGAHGYLLHQFLSPIANHRTDEYGGSLENRMRFPLEVFDAVREAFPAERPVWMRVSATDWVPN
GWDIEGTIALSHELKARGSAAVHVSTGGVSPQQAIKIGPGYQVPYAQRVKAEVGLPTMAVGLITEAEQAEAIIANNEADI
ISIARAMLYDPRWPWHAAAKLGASVNAPKQYWRSQPRGLEKLFKDAHFGQR

Sequences:

>Translated_371_residues
MPHLFDPYRIGNLELANRIAIAPMCQYSAQEGNATDWHMIHLGQMALSGAGLLIIEATAVSPEGRITPTDLGLYNDANEA
ALGRVLGAVRNHSPIAVTIQLAHAGRKASSEAPWDGGGQIRPDQPRGWQTFAPSAVPHAAGEVPPAALDKAGMKKIRDDF
VAAAKRAARLGIEGIEVHGAHGYLLHQFLSPIANHRTDEYGGSLENRMRFPLEVFDAVREAFPAERPVWMRVSATDWVPN
GWDIEGTIALSHELKARGSAAVHVSTGGVSPQQAIKIGPGYQVPYAQRVKAEVGLPTMAVGLITEAEQAEAIIANNEADI
ISIARAMLYDPRWPWHAAAKLGASVNAPKQYWRSQPRGLEKLFKDAHFGQR
>Mature_370_residues
PHLFDPYRIGNLELANRIAIAPMCQYSAQEGNATDWHMIHLGQMALSGAGLLIIEATAVSPEGRITPTDLGLYNDANEAA
LGRVLGAVRNHSPIAVTIQLAHAGRKASSEAPWDGGGQIRPDQPRGWQTFAPSAVPHAAGEVPPAALDKAGMKKIRDDFV
AAAKRAARLGIEGIEVHGAHGYLLHQFLSPIANHRTDEYGGSLENRMRFPLEVFDAVREAFPAERPVWMRVSATDWVPNG
WDIEGTIALSHELKARGSAAVHVSTGGVSPQQAIKIGPGYQVPYAQRVKAEVGLPTMAVGLITEAEQAEAIIANNEADII
SIARAMLYDPRWPWHAAAKLGASVNAPKQYWRSQPRGLEKLFKDAHFGQR

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=340, Percent_Identity=32.0588235294118, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1789463, Length=354, Percent_Identity=25.7062146892655, Blast_Score=114, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI17540738, Length=202, Percent_Identity=31.6831683168317, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17559802, Length=174, Percent_Identity=32.7586206896552, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI72001454, Length=204, Percent_Identity=31.8627450980392, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17559804, Length=174, Percent_Identity=34.4827586206897, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17564188, Length=204, Percent_Identity=30.3921568627451, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17565138, Length=183, Percent_Identity=31.6939890710383, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17566914, Length=112, Percent_Identity=35.7142857142857, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6325086, Length=234, Percent_Identity=32.9059829059829, Blast_Score=113, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6321973, Length=234, Percent_Identity=33.7606837606838, Blast_Score=109, Evalue=8e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 40142; Mature: 40011

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHLFDPYRIGNLELANRIAIAPMCQYSAQEGNATDWHMIHLGQMALSGAGLLIIEATAV
CCCCCCCEEECCEECCCEEEECHHHHCCCCCCCCCCEEEEEEHHHHHCCCCEEEEEEEEE
SPEGRITPTDLGLYNDANEAALGRVLGAVRNHSPIAVTIQLAHAGRKASSEAPWDGGGQI
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCC
RPDQPRGWQTFAPSAVPHAAGEVPPAALDKAGMKKIRDDFVAAAKRAARLGIEGIEVHGA
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
HGYLLHQFLSPIANHRTDEYGGSLENRMRFPLEVFDAVREAFPAERPVWMRVSATDWVPN
CHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCC
GWDIEGTIALSHELKARGSAAVHVSTGGVSPQQAIKIGPGYQVPYAQRVKAEVGLPTMAV
CCCCEEEEEEEEHHHCCCCEEEEEECCCCCHHHEEEECCCCCCCHHHHHHHHCCCCHHHH
GLITEAEQAEAIIANNEADIISIARAMLYDPRWPWHAAAKLGASVNAPKQYWRSQPRGLE
HHHHCHHHCCEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHCCCCHHHH
KLFKDAHFGQR
HHHHHHCCCCC
>Mature Secondary Structure 
PHLFDPYRIGNLELANRIAIAPMCQYSAQEGNATDWHMIHLGQMALSGAGLLIIEATAV
CCCCCCEEECCEECCCEEEECHHHHCCCCCCCCCCEEEEEEHHHHHCCCCEEEEEEEEE
SPEGRITPTDLGLYNDANEAALGRVLGAVRNHSPIAVTIQLAHAGRKASSEAPWDGGGQI
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCC
RPDQPRGWQTFAPSAVPHAAGEVPPAALDKAGMKKIRDDFVAAAKRAARLGIEGIEVHGA
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
HGYLLHQFLSPIANHRTDEYGGSLENRMRFPLEVFDAVREAFPAERPVWMRVSATDWVPN
CHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCC
GWDIEGTIALSHELKARGSAAVHVSTGGVSPQQAIKIGPGYQVPYAQRVKAEVGLPTMAV
CCCCEEEEEEEEHHHCCCCEEEEEECCCCCHHHEEEECCCCCCCHHHHHHHHCCCCHHHH
GLITEAEQAEAIIANNEADIISIARAMLYDPRWPWHAAAKLGASVNAPKQYWRSQPRGLE
HHHHCHHHCCEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHCCCCHHHH
KLFKDAHFGQR
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA