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The map label for this gene is fabG [H]

Identifier: 94313735

GI number: 94313735

Start: 1461127

End: 1461846

Strand: Reverse

Name: fabG [H]

Synonym: Rmet_4813

Alternate gene names: 94313735

Gene position: 1461846-1461127 (Counterclockwise)

Preceding gene: 94313737

Following gene: 94313730

Centisome position: 56.66

GC content: 65.28

Gene sequence:

>720_bases
ATGGACTCGACCGCTGCCCGTCGTCATGTCGTCATCACCGGAGCCGCCGGCGCGCTAGGCCGTGCAGTGGCCAGCCGCTT
TGCCGCCGAGGGTGCCAGATTGGCGCTGATCGACCGGGACCTGCAGCACTTGCAAAGCGTATTCGCTCATCCCGAGCCCG
ATCACGGCGGCACGCTGCTTCACGCGGCCGATGTCACGTCGGACACCGCGATGGCACCGGTTGCGGCGGCAATCCTCGAC
GCCTTCGGTACGGTAGACGTACTGGTGCATGTGGCCGGCGGCTTTGAAATGGGCGAGGCCACTCACGCCATGAGCCGGGA
ATCGTGGATGCGGATGATGGACCTGAATGCGTGGTCGTTCGTTGCGGTCACCAGCCACTTCATTCCCGCCATGCTGTTCC
AGAGGCACGGCAAAGTCGTTGCGGTGTCGGCGCGTGGTGCCATGGCCGGCGCGGCGACGATGGCGGCCTATGCGGCATCC
AAGAGCGCGCTGCAACGGCTCGTGGAAAGCCTGTCGCATGAGGTAAGGGGTGCAGGCATCAACGTGAACAGCGTCGCCCC
GAGTATCCTCGATACCCCGGCCAATCGTCAGGCCATGCCCTCGGTCGACCATACGCGCTGGGTATCGACCGGCGCCGCGG
CACGGGCGGTGGCGTTCCTGGCCTCTGATGCGGCAGAAGCGGTTCATGGGCAGCATATGGTGCTGGATGGGTTGAGTTGA

Upstream 100 bases:

>100_bases
GACGGTTGCACGCGCTGTACAGTTTCTCTTGCGACGTAGTATTTTTGCGAGACGGGCGGCAGAGGGCTATCGTTTAAGAA
CCCTCACCCTGGAGCGTTTC

Downstream 100 bases:

>100_bases
TCTGGGTCTCGGACGATTTCACTGGGAATAGGGCAGTTAGAAGCCGTTTCAAAAAGATCCTGGCGTCGTTGCGGGGCCTT
GCCTTACTACTTGTGCTGTC

Product: putative short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MDSTAARRHVVITGAAGALGRAVASRFAAEGARLALIDRDLQHLQSVFAHPEPDHGGTLLHAADVTSDTAMAPVAAAILD
AFGTVDVLVHVAGGFEMGEATHAMSRESWMRMMDLNAWSFVAVTSHFIPAMLFQRHGKVVAVSARGAMAGAATMAAYAAS
KSALQRLVESLSHEVRGAGINVNSVAPSILDTPANRQAMPSVDHTRWVSTGAAARAVAFLASDAAEAVHGQHMVLDGLS

Sequences:

>Translated_239_residues
MDSTAARRHVVITGAAGALGRAVASRFAAEGARLALIDRDLQHLQSVFAHPEPDHGGTLLHAADVTSDTAMAPVAAAILD
AFGTVDVLVHVAGGFEMGEATHAMSRESWMRMMDLNAWSFVAVTSHFIPAMLFQRHGKVVAVSARGAMAGAATMAAYAAS
KSALQRLVESLSHEVRGAGINVNSVAPSILDTPANRQAMPSVDHTRWVSTGAAARAVAFLASDAAEAVHGQHMVLDGLS
>Mature_239_residues
MDSTAARRHVVITGAAGALGRAVASRFAAEGARLALIDRDLQHLQSVFAHPEPDHGGTLLHAADVTSDTAMAPVAAAILD
AFGTVDVLVHVAGGFEMGEATHAMSRESWMRMMDLNAWSFVAVTSHFIPAMLFQRHGKVVAVSARGAMAGAATMAAYAAS
KSALQRLVESLSHEVRGAGINVNSVAPSILDTPANRQAMPSVDHTRWVSTGAAARAVAFLASDAAEAVHGQHMVLDGLS

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=228, Percent_Identity=31.5789473684211, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI157739938, Length=194, Percent_Identity=28.8659793814433, Blast_Score=81, Evalue=6e-16,
Organism=Homo sapiens, GI4503817, Length=195, Percent_Identity=29.2307692307692, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI66933014, Length=226, Percent_Identity=26.5486725663717, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI5031737, Length=248, Percent_Identity=28.2258064516129, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI33667109, Length=191, Percent_Identity=29.8429319371728, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=24.8979591836735, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI1787335, Length=235, Percent_Identity=29.7872340425532, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1786812, Length=248, Percent_Identity=29.0322580645161, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082160, Length=248, Percent_Identity=25.8064516129032, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87082100, Length=249, Percent_Identity=28.1124497991968, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1787820, Length=187, Percent_Identity=26.7379679144385, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787905, Length=239, Percent_Identity=27.6150627615063, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790717, Length=244, Percent_Identity=25.4098360655738, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=245, Percent_Identity=26.530612244898, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=270, Percent_Identity=27.4074074074074, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=257, Percent_Identity=25.6809338521401, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=257, Percent_Identity=26.4591439688716, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17508895, Length=193, Percent_Identity=28.4974093264249, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=25.2032520325203, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=256, Percent_Identity=26.5625, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=258, Percent_Identity=26.3565891472868, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17560676, Length=243, Percent_Identity=25.1028806584362, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17565030, Length=255, Percent_Identity=27.0588235294118, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=194, Percent_Identity=28.3505154639175, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=257, Percent_Identity=26.4591439688716, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=254, Percent_Identity=27.5590551181102, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=194, Percent_Identity=26.2886597938144, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=28.0487804878049, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=189, Percent_Identity=28.042328042328, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=195, Percent_Identity=29.2307692307692, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=192, Percent_Identity=25, Blast_Score=65, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6322861, Length=189, Percent_Identity=28.5714285714286, Blast_Score=63, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21357041, Length=247, Percent_Identity=28.3400809716599, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=28, Blast_Score=80, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24644339, Length=247, Percent_Identity=28.7449392712551, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356301, Length=211, Percent_Identity=27.9620853080569, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI23397609, Length=246, Percent_Identity=29.2682926829268, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=27.6923076923077, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21355631, Length=167, Percent_Identity=26.3473053892216, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI281364892, Length=191, Percent_Identity=26.1780104712042, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355319, Length=244, Percent_Identity=23.3606557377049, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 24852; Mature: 24852

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSTAARRHVVITGAAGALGRAVASRFAAEGARLALIDRDLQHLQSVFAHPEPDHGGTLL
CCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCCCCCCCEEE
HAADVTSDTAMAPVAAAILDAFGTVDVLVHVAGGFEMGEATHAMSRESWMRMMDLNAWSF
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHH
VAVTSHFIPAMLFQRHGKVVAVSARGAMAGAATMAAYAASKSALQRLVESLSHEVRGAGI
HHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NVNSVAPSILDTPANRQAMPSVDHTRWVSTGAAARAVAFLASDAAEAVHGQHMVLDGLS
CHHHCCCHHHCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEECCCC
>Mature Secondary Structure
MDSTAARRHVVITGAAGALGRAVASRFAAEGARLALIDRDLQHLQSVFAHPEPDHGGTLL
CCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCCCCCCCEEE
HAADVTSDTAMAPVAAAILDAFGTVDVLVHVAGGFEMGEATHAMSRESWMRMMDLNAWSF
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHH
VAVTSHFIPAMLFQRHGKVVAVSARGAMAGAATMAAYAASKSALQRLVESLSHEVRGAGI
HHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NVNSVAPSILDTPANRQAMPSVDHTRWVSTGAAARAVAFLASDAAEAVHGQHMVLDGLS
CHHHCCCHHHCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]