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The map label for this gene is nodT [H]

Identifier: 94313712

GI number: 94313712

Start: 1434297

End: 1435787

Strand: Reverse

Name: nodT [H]

Synonym: Rmet_4790

Alternate gene names: 94313712

Gene position: 1435787-1434297 (Counterclockwise)

Preceding gene: 94313713

Following gene: 94313711

Centisome position: 55.65

GC content: 66.13

Gene sequence:

>1491_bases
GTGAAACGCTTTGCCCGTGCCTCGCTGGCGGCGATGTTGCCGCTTGCGCTGGCCGCTTGCATGACCGTCGGCCCTGATCA
CAAGGTGCCCGACGATGCGGTCGTGAAGTCATCGGCCGCCAATGGACCGTTTGCCGGCACCGACAGCGATGCGGTGTCGA
TCGGCGACGTTCCGAACGACTGGTGGCGTCTGTACGACGATCCCCGTATCGACGAGCTGGTGCAGCAAGCGCTGGTGGCC
AACACCGACCTGCGTGTGGCCGCCGCCAATCTGAAGCGCTCGATCGCCGTGTATCACGAGGTGGAAGCCGAGAATCTGCC
GGAAACGAAGTTCCGGGCCAGTGCGGAGCGCGGCCAGATCGCTGGCGAACCGCTGCTGCACGAAGAGAAGATTCCGGTGA
TGAACTTCGGCGACATTGGTCTCAATGTTTCGTACCTGATTGACTTCTGGGGCAAGCTCAAGCGTGCCGACGAAGCCGCC
TTGGCATCGGCGCAGGCCAGCCATGCGGCGCTGGACCAAGCTCGTGTGGGCGTGGTGGCGGAGACCGTGCGTGCGTATGT
GCAAGGATGCACAGCCACGCACGAACTACATGTGGCCGCGCATCAGCTCGACCTGCAGGAACGCGGCGTGAAGCTGGCGC
AGAAACTGGTCGATGCTGGCCGAGGTCAGCCGACCGATCTGCTGCGCGCCGAGGCGCAAGCCGACACCCTGCGTTCGGCA
CTGCCGAAGTATCGTGCGGAGCAGGAAGGCGCGGCATACCGCCTGGCGGTAATGCTGGGCAAGCCGCCGACTGCGCTCGA
TGTCAGCAGCGTGGCGTGCGAGCACGTACCGGCGTTGAAGCAGGCGCTGCCCGTTGGCGATGGCATGGCGCTGCTCAAGC
GCCGACCGGACGTTCGCCAGGCCGAGCGCGAGCTGGCATCGGCAACGGCCAAGATCGGCGTGGCTACCGCTGACCTGTTC
CCGCAGATTCGCATCGGTGCATCGGCAGGTTTCACCGGTATCCTCGACCACCTTGGTCAGGCGCCGACCGCGCACTGGGG
CTGGGGCCCCGCGATCTCGTGGACGATCCCGACCAGCGGCACGCGCGCGCGCATCCACAACATGGAGTACGGGGCCGAAG
GGGCGCTGGCTCATTTCGACGGCGTGGTGCTGAAGGCGCTGCGCGAGACGCAGACTGCGCTGTCGGCCTATACGCACGAA
CTGGACCGGAACGCGTCGCTGCGCTCGGCGCGCGACAAGGCCAATGAGGCAGCCCGCCAGAACCGGCTGCTGTGGCAGGC
AGGCCGATCGCCGTATCTGCAGAGCCTGGATGCCGACCGCACGCTGGCCAATACCGATGCCGCGCTGGCCGCATCCGACG
CGCAGGTTGCGATGGATCAGATCAACCTGTTCCTGGCGCTTGGTGGTGGATGGCAGGATGCGCCGGCCATTGCCAGTCAT
CCGGTGGGCAAGGAGCCCGGACAGGCCACGGAACACACCGAGGAGCACTGA

Upstream 100 bases:

>100_bases
AAACGGGAGACAAGCCGACCGCGCCGGCGGCCGGCCGTAGTGCCTCGCAGGACAAGGTTGCGCTGGCCGGCAAGCGCGCG
CCCTCAACCGGAGCAGTGCA

Downstream 100 bases:

>100_bases
GGAGCGCCGAGGAACAATAAGGTAAGCTTCGGCCTCGGCCACGCCTTGGCTGCACTATCGAACTGATTCCGGCGTCGTTG
CGCGGCTTCGCCGTACGATT

Product: NodT family RND efflux system outer membrane lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MKRFARASLAAMLPLALAACMTVGPDHKVPDDAVVKSSAANGPFAGTDSDAVSIGDVPNDWWRLYDDPRIDELVQQALVA
NTDLRVAAANLKRSIAVYHEVEAENLPETKFRASAERGQIAGEPLLHEEKIPVMNFGDIGLNVSYLIDFWGKLKRADEAA
LASAQASHAALDQARVGVVAETVRAYVQGCTATHELHVAAHQLDLQERGVKLAQKLVDAGRGQPTDLLRAEAQADTLRSA
LPKYRAEQEGAAYRLAVMLGKPPTALDVSSVACEHVPALKQALPVGDGMALLKRRPDVRQAERELASATAKIGVATADLF
PQIRIGASAGFTGILDHLGQAPTAHWGWGPAISWTIPTSGTRARIHNMEYGAEGALAHFDGVVLKALRETQTALSAYTHE
LDRNASLRSARDKANEAARQNRLLWQAGRSPYLQSLDADRTLANTDAALAASDAQVAMDQINLFLALGGGWQDAPAIASH
PVGKEPGQATEHTEEH

Sequences:

>Translated_496_residues
MKRFARASLAAMLPLALAACMTVGPDHKVPDDAVVKSSAANGPFAGTDSDAVSIGDVPNDWWRLYDDPRIDELVQQALVA
NTDLRVAAANLKRSIAVYHEVEAENLPETKFRASAERGQIAGEPLLHEEKIPVMNFGDIGLNVSYLIDFWGKLKRADEAA
LASAQASHAALDQARVGVVAETVRAYVQGCTATHELHVAAHQLDLQERGVKLAQKLVDAGRGQPTDLLRAEAQADTLRSA
LPKYRAEQEGAAYRLAVMLGKPPTALDVSSVACEHVPALKQALPVGDGMALLKRRPDVRQAERELASATAKIGVATADLF
PQIRIGASAGFTGILDHLGQAPTAHWGWGPAISWTIPTSGTRARIHNMEYGAEGALAHFDGVVLKALRETQTALSAYTHE
LDRNASLRSARDKANEAARQNRLLWQAGRSPYLQSLDADRTLANTDAALAASDAQVAMDQINLFLALGGGWQDAPAIASH
PVGKEPGQATEHTEEH
>Mature_496_residues
MKRFARASLAAMLPLALAACMTVGPDHKVPDDAVVKSSAANGPFAGTDSDAVSIGDVPNDWWRLYDDPRIDELVQQALVA
NTDLRVAAANLKRSIAVYHEVEAENLPETKFRASAERGQIAGEPLLHEEKIPVMNFGDIGLNVSYLIDFWGKLKRADEAA
LASAQASHAALDQARVGVVAETVRAYVQGCTATHELHVAAHQLDLQERGVKLAQKLVDAGRGQPTDLLRAEAQADTLRSA
LPKYRAEQEGAAYRLAVMLGKPPTALDVSSVACEHVPALKQALPVGDGMALLKRRPDVRQAERELASATAKIGVATADLF
PQIRIGASAGFTGILDHLGQAPTAHWGWGPAISWTIPTSGTRARIHNMEYGAEGALAHFDGVVLKALRETQTALSAYTHE
LDRNASLRSARDKANEAARQNRLLWQAGRSPYLQSLDADRTLANTDAALAASDAQVAMDQINLFLALGGGWQDAPAIASH
PVGKEPGQATEHTEEH

Specific function: In Pathogenic Strains It Allows The Bacteria To Invade Brain Microvascular Endothelial Cells (Bmec) Thus Allowing It To Cross The Blood-Brain Barrier And Cause Neonatal Meningitis. [C]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=466, Percent_Identity=27.0386266094421, Blast_Score=132, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 53097; Mature: 53097

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRFARASLAAMLPLALAACMTVGPDHKVPDDAVVKSSAANGPFAGTDSDAVSIGDVPND
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCCCEEECCCCCH
WWRLYDDPRIDELVQQALVANTDLRVAAANLKRSIAVYHEVEAENLPETKFRASAERGQI
HHHCCCCCCHHHHHHHHHHCCCCHHEEHHHHHHHHHHHEECCCCCCCCHHHHHCHHCCCC
AGEPLLHEEKIPVMNFGDIGLNVSYLIDFWGKLKRADEAALASAQASHAALDQARVGVVA
CCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETVRAYVQGCTATHELHVAAHQLDLQERGVKLAQKLVDAGRGQPTDLLRAEAQADTLRSA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LPKYRAEQEGAAYRLAVMLGKPPTALDVSSVACEHVPALKQALPVGDGMALLKRRPDVRQ
HHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHH
AERELASATAKIGVATADLFPQIRIGASAGFTGILDHLGQAPTAHWGWGPAISWTIPTSG
HHHHHHHHHHHHCCHHHHHCCCEEECCCCCHHHHHHHHCCCCCCCCCCCCEEEEECCCCC
TRARIHNMEYGAEGALAHFDGVVLKALRETQTALSAYTHELDRNASLRSARDKANEAARQ
CCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
NRLLWQAGRSPYLQSLDADRTLANTDAALAASDAQVAMDQINLFLALGGGWQDAPAIASH
HHHHHHCCCCHHHHHCCCCCHHCCCCHHHCCCHHHHHHHHEEEEEEECCCCCCCCCHHCC
PVGKEPGQATEHTEEH
CCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKRFARASLAAMLPLALAACMTVGPDHKVPDDAVVKSSAANGPFAGTDSDAVSIGDVPND
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCCCEEECCCCCH
WWRLYDDPRIDELVQQALVANTDLRVAAANLKRSIAVYHEVEAENLPETKFRASAERGQI
HHHCCCCCCHHHHHHHHHHCCCCHHEEHHHHHHHHHHHEECCCCCCCCHHHHHCHHCCCC
AGEPLLHEEKIPVMNFGDIGLNVSYLIDFWGKLKRADEAALASAQASHAALDQARVGVVA
CCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETVRAYVQGCTATHELHVAAHQLDLQERGVKLAQKLVDAGRGQPTDLLRAEAQADTLRSA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LPKYRAEQEGAAYRLAVMLGKPPTALDVSSVACEHVPALKQALPVGDGMALLKRRPDVRQ
HHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHH
AERELASATAKIGVATADLFPQIRIGASAGFTGILDHLGQAPTAHWGWGPAISWTIPTSG
HHHHHHHHHHHHCCHHHHHCCCEEECCCCCHHHHHHHHCCCCCCCCCCCCEEEEECCCCC
TRARIHNMEYGAEGALAHFDGVVLKALRETQTALSAYTHELDRNASLRSARDKANEAARQ
CCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
NRLLWQAGRSPYLQSLDADRTLANTDAALAASDAQVAMDQINLFLALGGGWQDAPAIASH
HHHHHHCCCCHHHHHCCCCCHHCCCCHHHCCCHHHHHHHHEEEEEEECCCCCCCCCHHCC
PVGKEPGQATEHTEEH
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2338917; 2622339 [H]