| Definition | Cupriavidus metallidurans CH34 megaplasmid, complete sequence. |
|---|---|
| Accession | NC_007974 |
| Length | 2,580,084 |
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The map label for this gene is livF10 [H]
Identifier: 94313700
GI number: 94313700
Start: 1422430
End: 1423131
Strand: Reverse
Name: livF10 [H]
Synonym: Rmet_4778
Alternate gene names: 94313700
Gene position: 1423131-1422430 (Counterclockwise)
Preceding gene: 94313701
Following gene: 94313698
Centisome position: 55.16
GC content: 66.52
Gene sequence:
>702_bases ATGAGTGATCTGCTACGGCTGGAGACTGTCAGCGCCGGATATGGCGAGGCGACGGTGCTCGAGCAGATCGATCTGGCGCT GGGCGCCGGCGACAGCCTCGCGCTGCTGGGCCGTAACGGCGTAGGCAAGACTACGTTGCTGTCCACGCTGATGGGCTTCA CGCGATTGCGTGGGGGCAAGCTGGTCTGGCAAGGGCGGGATCTGGCCAGGGTGCCGCCGCATCGCCGTGCGCAGAGCGGC ATCGGCTGGGTGCCGCAGGAGCGCTGGGTCTTTCCCTCGCTGACCGTGGAGGAGCATCTCGGCGCGGTGGCCCGGCCCGG GCCATGGGATGTCCAGCGTGTGTATCGGACCTTTCCGAGGTTGGGTGAGCGTCGGCGTAATCTCGGCAACCAGTTGTCTG GCGGGGAGCAGCAGATGCTGGCCATTGGCCGGGCACTGATGGTCAACCCCGCCCTGTTGCTGCTGGACGAGCCGATGGAA GGGCTGGCGCCGGTCATCGTGCAGGAGTTGCAGCGCGTGATCGCAGGGCTGATCGCAGACGCGGGCATGGCTGTGATCGT GGTGGAGCAACACGCGCGGTTGGCGTTGGGCATGACCCGGCAGGCGATTGTTCTGGACCGGGGCCGAGTGGTGCACCGGT CGGATAGCGCAACACTGCTGGCCAACAAGGCGTTGCTGGATCGGCTGGTTTCGGTCCGATAG
Upstream 100 bases:
>100_bases ATCACGGTGCTGGTGGCCGGGCGCGTATTGATGGAAGGGACGCCGGCTGAAGTCTCCACCGACCCAAGAGTGCGTGAGGT CTATCTTGGAGAGGCCGCCC
Downstream 100 bases:
>100_bases CAGGGGGCGGGGCGTTCGCATTAGTGCTCGGACGATTCCGAACGTTTTCGGAATCGTCTTATATCCGTGTGGTCTCCCGG CTTTGACAATGCATGGGTCG
Product: high-affinity branched-chain amino acid ABC transporterATP binding protein
Products: ADP; phosphate; L-leucine [Cytoplasm]; ADP; L-valine [Cytoplasm]; L-iso-leucine [Cytoplasm] [C]
Alternate protein names: LIV-I protein F [H]
Number of amino acids: Translated: 233; Mature: 232
Protein sequence:
>233_residues MSDLLRLETVSAGYGEATVLEQIDLALGAGDSLALLGRNGVGKTTLLSTLMGFTRLRGGKLVWQGRDLARVPPHRRAQSG IGWVPQERWVFPSLTVEEHLGAVARPGPWDVQRVYRTFPRLGERRRNLGNQLSGGEQQMLAIGRALMVNPALLLLDEPME GLAPVIVQELQRVIAGLIADAGMAVIVVEQHARLALGMTRQAIVLDRGRVVHRSDSATLLANKALLDRLVSVR
Sequences:
>Translated_233_residues MSDLLRLETVSAGYGEATVLEQIDLALGAGDSLALLGRNGVGKTTLLSTLMGFTRLRGGKLVWQGRDLARVPPHRRAQSG IGWVPQERWVFPSLTVEEHLGAVARPGPWDVQRVYRTFPRLGERRRNLGNQLSGGEQQMLAIGRALMVNPALLLLDEPME GLAPVIVQELQRVIAGLIADAGMAVIVVEQHARLALGMTRQAIVLDRGRVVHRSDSATLLANKALLDRLVSVR >Mature_232_residues SDLLRLETVSAGYGEATVLEQIDLALGAGDSLALLGRNGVGKTTLLSTLMGFTRLRGGKLVWQGRDLARVPPHRRAQSGI GWVPQERWVFPSLTVEEHLGAVARPGPWDVQRVYRTFPRLGERRRNLGNQLSGGEQQMLAIGRALMVNPALLLLDEPMEG LAPVIVQELQRVIAGLIADAGMAVIVVEQHARLALGMTRQAIVLDRGRVVHRSDSATLLANKALLDRLVSVR
Specific function: Component of the leucine-specific transport system [H]
COG id: COG0410
COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI153792144, Length=195, Percent_Identity=26.6666666666667, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI9955968, Length=247, Percent_Identity=29.1497975708502, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI9955966, Length=247, Percent_Identity=29.1497975708502, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI45243524, Length=247, Percent_Identity=29.1497975708502, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI27262624, Length=151, Percent_Identity=33.112582781457, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI27262626, Length=151, Percent_Identity=33.112582781457, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI31657092, Length=213, Percent_Identity=27.6995305164319, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI27477115, Length=143, Percent_Identity=34.2657342657343, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI42741659, Length=238, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI4505771, Length=231, Percent_Identity=29.4372294372294, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI9961252, Length=231, Percent_Identity=29.4372294372294, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI27881501, Length=216, Percent_Identity=26.8518518518519, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI30795238, Length=216, Percent_Identity=26.8518518518519, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI171184400, Length=230, Percent_Identity=30, Blast_Score=68, Evalue=8e-12, Organism=Homo sapiens, GI45446740, Length=221, Percent_Identity=25.3393665158371, Blast_Score=68, Evalue=8e-12, Organism=Homo sapiens, GI47078218, Length=221, Percent_Identity=25.3393665158371, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI6005701, Length=195, Percent_Identity=25.1282051282051, Blast_Score=66, Evalue=2e-11, Organism=Homo sapiens, GI42490749, Length=223, Percent_Identity=29.1479820627803, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI150417984, Length=152, Percent_Identity=34.2105263157895, Blast_Score=65, Evalue=5e-11, Organism=Escherichia coli, GI87082268, Length=227, Percent_Identity=42.7312775330396, Blast_Score=162, Evalue=1e-41, Organism=Escherichia coli, GI1789593, Length=226, Percent_Identity=31.4159292035398, Blast_Score=111, Evalue=3e-26, Organism=Escherichia coli, GI1789672, Length=227, Percent_Identity=28.6343612334802, Blast_Score=101, Evalue=4e-23, Organism=Escherichia coli, GI1787029, Length=231, Percent_Identity=29.004329004329, Blast_Score=100, Evalue=6e-23, Organism=Escherichia coli, GI87081791, Length=217, Percent_Identity=29.4930875576037, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1787370, Length=219, Percent_Identity=29.6803652968037, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1787792, Length=189, Percent_Identity=32.2751322751323, Blast_Score=89, Evalue=2e-19, Organism=Escherichia coli, GI1787712, Length=216, Percent_Identity=29.1666666666667, Blast_Score=88, Evalue=5e-19, Organism=Escherichia coli, GI1786872, Length=225, Percent_Identity=29.3333333333333, Blast_Score=88, Evalue=5e-19, Organism=Escherichia coli, GI1790467, Length=234, Percent_Identity=29.0598290598291, Blast_Score=88, Evalue=6e-19, Organism=Escherichia coli, GI1787089, Length=227, Percent_Identity=29.5154185022026, Blast_Score=85, Evalue=3e-18, Organism=Escherichia coli, GI1790190, Length=240, Percent_Identity=26.25, Blast_Score=85, Evalue=4e-18, Organism=Escherichia coli, GI1786253, Length=210, Percent_Identity=29.0476190476191, Blast_Score=84, Evalue=7e-18, Organism=Escherichia coli, GI87081834, Length=211, Percent_Identity=27.9620853080569, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI1788225, Length=219, Percent_Identity=30.5936073059361, Blast_Score=82, Evalue=4e-17, Organism=Escherichia coli, GI1786319, Length=233, Percent_Identity=31.3304721030043, Blast_Score=81, Evalue=5e-17, Organism=Escherichia coli, GI1788450, Length=228, Percent_Identity=25.4385964912281, Blast_Score=81, Evalue=5e-17, Organism=Escherichia coli, GI87081709, Length=219, Percent_Identity=26.9406392694064, Blast_Score=81, Evalue=7e-17, Organism=Escherichia coli, GI1789864, Length=216, Percent_Identity=26.8518518518519, Blast_Score=81, Evalue=7e-17, Organism=Escherichia coli, GI1787164, Length=207, Percent_Identity=31.4009661835749, Blast_Score=80, Evalue=8e-17, Organism=Escherichia coli, GI1788761, Length=216, Percent_Identity=28.2407407407407, Blast_Score=80, Evalue=9e-17, Organism=Escherichia coli, GI1786563, Length=220, Percent_Identity=30.4545454545455, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1787112, Length=232, Percent_Identity=31.8965517241379, Blast_Score=75, Evalue=3e-15, Organism=Escherichia coli, GI1789873, Length=182, Percent_Identity=31.3186813186813, Blast_Score=75, Evalue=3e-15, Organism=Escherichia coli, GI1788165, Length=209, Percent_Identity=29.1866028708134, Blast_Score=74, Evalue=7e-15, Organism=Escherichia coli, GI1790544, Length=237, Percent_Identity=26.5822784810127, Blast_Score=74, Evalue=8e-15, Organism=Escherichia coli, GI48995001, Length=226, Percent_Identity=27.8761061946903, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1786654, Length=236, Percent_Identity=27.9661016949153, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI48994943, Length=169, Percent_Identity=34.9112426035503, Blast_Score=72, Evalue=2e-14, Organism=Escherichia coli, GI1786703, Length=201, Percent_Identity=28.8557213930348, Blast_Score=69, Evalue=2e-13, Organism=Escherichia coli, GI87082267, Length=167, Percent_Identity=28.7425149700599, Blast_Score=68, Evalue=5e-13, Organism=Escherichia coli, GI1787105, Length=208, Percent_Identity=31.25, Blast_Score=68, Evalue=6e-13, Organism=Escherichia coli, GI87081782, Length=227, Percent_Identity=24.6696035242291, Blast_Score=67, Evalue=7e-13, Organism=Escherichia coli, GI1788472, Length=216, Percent_Identity=25, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1789751, Length=219, Percent_Identity=31.9634703196347, Blast_Score=65, Evalue=3e-12, Organism=Escherichia coli, GI1786398, Length=234, Percent_Identity=23.0769230769231, Blast_Score=64, Evalue=6e-12, Organism=Escherichia coli, GI1788210, Length=222, Percent_Identity=27.4774774774775, Blast_Score=64, Evalue=6e-12, Organism=Escherichia coli, GI1787041, Length=172, Percent_Identity=29.6511627906977, Blast_Score=64, Evalue=8e-12, Organism=Escherichia coli, GI1788506, Length=222, Percent_Identity=27.4774774774775, Blast_Score=64, Evalue=9e-12, Organism=Escherichia coli, GI1788897, Length=197, Percent_Identity=27.4111675126904, Blast_Score=62, Evalue=3e-11, Organism=Escherichia coli, GI1789991, Length=228, Percent_Identity=24.5614035087719, Blast_Score=61, Evalue=7e-11, Organism=Escherichia coli, GI1789032, Length=251, Percent_Identity=23.1075697211155, Blast_Score=61, Evalue=8e-11, Organism=Escherichia coli, GI48994997, Length=221, Percent_Identity=25.7918552036199, Blast_Score=61, Evalue=8e-11, Organism=Caenorhabditis elegans, GI193211017, Length=235, Percent_Identity=29.3617021276596, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI193211015, Length=235, Percent_Identity=29.3617021276596, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI71996809, Length=235, Percent_Identity=29.3617021276596, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI212646699, Length=239, Percent_Identity=29.7071129707113, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI193202349, Length=224, Percent_Identity=30.8035714285714, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI115533592, Length=195, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI193209708, Length=225, Percent_Identity=28, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17541710, Length=240, Percent_Identity=28.75, Blast_Score=73, Evalue=9e-14, Organism=Caenorhabditis elegans, GI71988343, Length=238, Percent_Identity=25.2100840336134, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17565938, Length=236, Percent_Identity=28.3898305084746, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI71983516, Length=152, Percent_Identity=31.5789473684211, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI71983510, Length=152, Percent_Identity=31.5789473684211, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI71983523, Length=152, Percent_Identity=31.5789473684211, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17558664, Length=224, Percent_Identity=27.6785714285714, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17565586, Length=154, Percent_Identity=29.8701298701299, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17510237, Length=153, Percent_Identity=31.3725490196078, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI25146777, Length=222, Percent_Identity=25.6756756756757, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6323959, Length=235, Percent_Identity=28.0851063829787, Blast_Score=67, Evalue=3e-12, Organism=Drosophila melanogaster, GI24582014, Length=197, Percent_Identity=30.9644670050761, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI24582012, Length=197, Percent_Identity=30.9644670050761, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI24641565, Length=243, Percent_Identity=28.8065843621399, Blast_Score=82, Evalue=2e-16, Organism=Drosophila melanogaster, GI24666092, Length=177, Percent_Identity=30.5084745762712, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI116007184, Length=237, Percent_Identity=27.4261603375527, Blast_Score=73, Evalue=1e-13, Organism=Drosophila melanogaster, GI221500365, Length=237, Percent_Identity=27.4261603375527, Blast_Score=73, Evalue=1e-13, Organism=Drosophila melanogaster, GI23397593, Length=223, Percent_Identity=31.390134529148, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI24650853, Length=183, Percent_Identity=29.5081967213115, Blast_Score=70, Evalue=9e-13, Organism=Drosophila melanogaster, GI24650855, Length=183, Percent_Identity=29.5081967213115, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI85726357, Length=240, Percent_Identity=27.9166666666667, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI21357907, Length=226, Percent_Identity=25.6637168141593, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI281362751, Length=183, Percent_Identity=29.5081967213115, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI85725262, Length=187, Percent_Identity=29.9465240641711, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI24581387, Length=230, Percent_Identity=29.5652173913043, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI24581383, Length=228, Percent_Identity=28.9473684210526, Blast_Score=67, Evalue=7e-12, Organism=Drosophila melanogaster, GI24581385, Length=228, Percent_Identity=28.9473684210526, Blast_Score=67, Evalue=7e-12, Organism=Drosophila melanogaster, GI28574744, Length=209, Percent_Identity=26.7942583732057, Blast_Score=67, Evalue=8e-12, Organism=Drosophila melanogaster, GI28574150, Length=204, Percent_Identity=25.9803921568627, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI116007328, Length=204, Percent_Identity=25.9803921568627, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI24648314, Length=213, Percent_Identity=24.4131455399061, Blast_Score=64, Evalue=6e-11, Organism=Drosophila melanogaster, GI281363262, Length=219, Percent_Identity=29.2237442922374, Blast_Score=64, Evalue=7e-11, Organism=Drosophila melanogaster, GI24653245, Length=219, Percent_Identity=29.2237442922374, Blast_Score=64, Evalue=8e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 25382; Mature: 25251
Theoretical pI: Translated: 11.16; Mature: 11.16
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 3.0 %Met (Translated Protein) 3.0 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 2.6 %Met (Mature Protein) 2.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSDLLRLETVSAGYGEATVLEQIDLALGAGDSLALLGRNGVGKTTLLSTLMGFTRLRGGK CCCCHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCE LVWQGRDLARVPPHRRAQSGIGWVPQERWVFPSLTVEEHLGAVARPGPWDVQRVYRTFPR EEECCCCCCCCCCCHHHHCCCCCCCCCCEECCCCCHHHHCCCCCCCCCHHHHHHHHHHHH LGERRRNLGNQLSGGEQQMLAIGRALMVNPALLLLDEPMEGLAPVIVQELQRVIAGLIAD HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHC AGMAVIVVEQHARLALGMTRQAIVLDRGRVVHRSDSATLLANKALLDRLVSVR CCEEEEEEECCHHHHHCCCHHEEEEECCCEEECCCCCHHHHHHHHHHHHHHCC >Mature Secondary Structure SDLLRLETVSAGYGEATVLEQIDLALGAGDSLALLGRNGVGKTTLLSTLMGFTRLRGGK CCCHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCE LVWQGRDLARVPPHRRAQSGIGWVPQERWVFPSLTVEEHLGAVARPGPWDVQRVYRTFPR EEECCCCCCCCCCCHHHHCCCCCCCCCCEECCCCCHHHHCCCCCCCCCHHHHHHHHHHHH LGERRRNLGNQLSGGEQQMLAIGRALMVNPALLLLDEPMEGLAPVIVQELQRVIAGLIAD HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHC AGMAVIVVEQHARLALGMTRQAIVLDRGRVVHRSDSATLLANKALLDRLVSVR CCEEEEEEECCHHHHHCCCHHEEEEECCCEEECCCCCHHHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; L-leucine [Periplasm]; H2O; ATP; L-valine [Periplasm]; L-iso-leucine [Periplasm] [C]
Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2195019; 8041620; 9278503 [H]