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The map label for this gene is hexR [H]

Identifier: 94313693

GI number: 94313693

Start: 1415562

End: 1416467

Strand: Direct

Name: hexR [H]

Synonym: Rmet_4771

Alternate gene names: 94313693

Gene position: 1415562-1416467 (Clockwise)

Preceding gene: 94313689

Following gene: 94313694

Centisome position: 54.86

GC content: 65.89

Gene sequence:

>906_bases
ATGACCGCGCCCTTCGACATCCTGACCCGCATCGCCGAGCGTGGCCCGTCATTGCGACTGGCCGAGCAGAAAGTGGCGCA
GGTGATCCTTGAGGATCTTGCAGGGGCGGCGGCTGCCAGCATCAACGAACTGGCACGCAAGGCGGCGGTCAGCGAGGCAA
GTGTCACGCGCTTCGCAAAGGCCATCGGTTGCCGCGACGTCCGCGATCTGAAACTGCGCCTGGCACAAGCCACGGCAGTC
GGATCGCGTTTCCTGCAACCGGCGCCGGGCCCGGTCGATACTGACGCACCGGCCGCGCTGGCCGAGCGCATCCACGCCGA
CGTTCTCGCCACGCTCGAAGTCAACCGAAAGCTGATCGATCCCGAGCGGATTGACATTGCCGCGCGCCTGTTACTCAACG
CACGCATGGTCTACGCTTTTGGCATGGGTGGAGGCTCGACCTTCATGGCCGACGAGGCGCGGTATCGGCTGGCGCGATTG
GGGCACCCGGTGGCCACGTATCACGACGCGCTGCTGCAGAAGATGGTCGCCGCAACACTGACGCGCGATGACGTGGTACT
GGCGTTCTCGGCCAGCGGCAGCGTGCCGGAGATACTGGCCAGTTGCGATATCGCGCGCGAGTATGGCGCGCGGCTGATTG
CCGTGACCGCGCTTGGCTCGCCGCTGGCCGCGCGCGCCGACGTGCTCCTGCCCGTGCGGACGCTGGAAACGGATTTCATC
TTCAAGCCGTCGGCCTCGCGCTACGCGATGCTGATGGTGCTGGACGTACTGTCCACCCGCTTTGCGCTGCTGCAACAGGA
GCAAAGCAAGGAAAAGTTGCGCCGGCTGAAATACGTGCTGGATGCCCACCGAGGCGTCAGCCAGGACAGCGACGGGCCGG
ACAGCCGCCAGCCGCTCGGAGACTGA

Upstream 100 bases:

>100_bases
GTAATGATAGCCTTGAAACTACGATATTTCATCCTTGTTAGAAAGTAACATGCTTCGTCGGCCGAGGTGACCGGCGGGGC
CCGCCCACCCACCGTACGCC

Downstream 100 bases:

>100_bases
CAATGCCACACCTGTTCGATACCCTGATCCGCTGCGTGCTGCTGCTCGATGGCTCGGGCGCCGCGGCGCGCCTGGCCGAC
GTGGCGATCCGCGATGGCCG

Product: putative transcriptional regulator of the RpiR family

Products: NA

Alternate protein names: Hex regulon repressor [H]

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MTAPFDILTRIAERGPSLRLAEQKVAQVILEDLAGAAAASINELARKAAVSEASVTRFAKAIGCRDVRDLKLRLAQATAV
GSRFLQPAPGPVDTDAPAALAERIHADVLATLEVNRKLIDPERIDIAARLLLNARMVYAFGMGGGSTFMADEARYRLARL
GHPVATYHDALLQKMVAATLTRDDVVLAFSASGSVPEILASCDIAREYGARLIAVTALGSPLAARADVLLPVRTLETDFI
FKPSASRYAMLMVLDVLSTRFALLQQEQSKEKLRRLKYVLDAHRGVSQDSDGPDSRQPLGD

Sequences:

>Translated_301_residues
MTAPFDILTRIAERGPSLRLAEQKVAQVILEDLAGAAAASINELARKAAVSEASVTRFAKAIGCRDVRDLKLRLAQATAV
GSRFLQPAPGPVDTDAPAALAERIHADVLATLEVNRKLIDPERIDIAARLLLNARMVYAFGMGGGSTFMADEARYRLARL
GHPVATYHDALLQKMVAATLTRDDVVLAFSASGSVPEILASCDIAREYGARLIAVTALGSPLAARADVLLPVRTLETDFI
FKPSASRYAMLMVLDVLSTRFALLQQEQSKEKLRRLKYVLDAHRGVSQDSDGPDSRQPLGD
>Mature_300_residues
TAPFDILTRIAERGPSLRLAEQKVAQVILEDLAGAAAASINELARKAAVSEASVTRFAKAIGCRDVRDLKLRLAQATAVG
SRFLQPAPGPVDTDAPAALAERIHADVLATLEVNRKLIDPERIDIAARLLLNARMVYAFGMGGGSTFMADEARYRLARLG
HPVATYHDALLQKMVAATLTRDDVVLAFSASGSVPEILASCDIAREYGARLIAVTALGSPLAARADVLLPVRTLETDFIF
KPSASRYAMLMVLDVLSTRFALLQQEQSKEKLRRLKYVLDAHRGVSQDSDGPDSRQPLGD

Specific function: Represses the expression of the hex regulon (zwf, eda, glp and gap) [H]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=280, Percent_Identity=32.5, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI87082369, Length=261, Percent_Identity=26.4367816091954, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1788767, Length=256, Percent_Identity=26.5625, Blast_Score=89, Evalue=3e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 32488; Mature: 32357

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPFDILTRIAERGPSLRLAEQKVAQVILEDLAGAAAASINELARKAAVSEASVTRFAK
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIGCRDVRDLKLRLAQATAVGSRFLQPAPGPVDTDAPAALAERIHADVLATLEVNRKLID
HHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHCC
PERIDIAARLLLNARMVYAFGMGGGSTFMADEARYRLARLGHPVATYHDALLQKMVAATL
HHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
TRDDVVLAFSASGSVPEILASCDIAREYGARLIAVTALGSPLAARADVLLPVRTLETDFI
CCCCEEEEEECCCCHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHCHHEEEHHHCCCCEE
FKPSASRYAMLMVLDVLSTRFALLQQEQSKEKLRRLKYVLDAHRGVSQDSDGPDSRQPLG
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
D
C
>Mature Secondary Structure 
TAPFDILTRIAERGPSLRLAEQKVAQVILEDLAGAAAASINELARKAAVSEASVTRFAK
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIGCRDVRDLKLRLAQATAVGSRFLQPAPGPVDTDAPAALAERIHADVLATLEVNRKLID
HHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHCC
PERIDIAARLLLNARMVYAFGMGGGSTFMADEARYRLARLGHPVATYHDALLQKMVAATL
HHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
TRDDVVLAFSASGSVPEILASCDIAREYGARLIAVTALGSPLAARADVLLPVRTLETDFI
CCCCEEEEEECCCCHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHCHHEEEHHHCCCCEE
FKPSASRYAMLMVLDVLSTRFALLQQEQSKEKLRRLKYVLDAHRGVSQDSDGPDSRQPLG
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
D
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]