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The map label for this gene is degU [H]

Identifier: 94313637

GI number: 94313637

Start: 1358114

End: 1358908

Strand: Reverse

Name: degU [H]

Synonym: Rmet_4715

Alternate gene names: 94313637

Gene position: 1358908-1358114 (Counterclockwise)

Preceding gene: 291481537

Following gene: 94313635

Centisome position: 52.67

GC content: 58.62

Gene sequence:

>795_bases
ATGAATAACAACTGCAGTGTGCTGATCGTGGAAGACCATAATCTTCTGCGCGCGGGTTTGCGTTCGATGCTGTCCGCGCA
AATGGGATATCACGTGGCGGGGGAGGCAAGAGATGGCCGGGAGGCCTGCCAATTGGCAATCTCGCTGTGCCCGGATCTGA
TATTGATGGATCTTTCGCTCCCCGGCATGAACGGTATCGATGCCATTGCAGCAATCAAGCGCCGATCTCCTGGTATTCGG
ATAATTGCGCTTTCGGTGCACCAGAACGACGAATATGTGCGCGAGGCATTGCGGGCAGGCGTCGACGGCTATGTACTGAA
AGACACCTCCTTCGATGATCTGGTGACCGCGATGCGCGTCGTCCTGCTGGGCAAGAAACATCTGAGCCCGGAGCTCTACG
GCAATCTTGTGGAGTCCTACGTCAGCGGCCATGAAATGTCGACCGCCAAGACCGGATGGGACCTGCTGACGGCACGGGAG
CGCAGCGTTCTCAAGCTGGTGGCCGAAGGGCGCTCGAACCGGCAAGTCGGCATCTACATGAATCTCAGCCCGAAGACGAT
CGAGAAGTATCGGGCGAGCTTGATGCGCAAGCTCGGCATCACCAACCTGACGGAACTGGTGCTGATCGCCATCAGCATGG
GGCTGATCACATCGTTGGCGCGGAAGTATTGCGACGACAATCATCCATCCGTGACGAACCATGACGGGCTGGATGCCGTA
CCACTTCCCGCAGTACGCCGGCAGATGCTGGACGAGGGGCGCGCCGCCGGTTCGGATGGTGAGGCTTCCCCATGA

Upstream 100 bases:

>100_bases
TGATTCATGCTGCCCCCGCGTTGAAATACGTGTCGCCTCGGACACGTTTTCAATGTGGATGCCGCTCGCACTTCCGCGTA
GTTCGAAGTGGGAGGCGCAA

Downstream 100 bases:

>100_bases
CTGCGGAACGAGTGACAGGGTAGCGGGAGGGTCTGCCCGATCAGACCCTCCATGCAGCGCTGACCAGGGTTCCGCTACCT
TGGCCTGACGTCAGCGCAAA

Product: LuxR family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MNNNCSVLIVEDHNLLRAGLRSMLSAQMGYHVAGEARDGREACQLAISLCPDLILMDLSLPGMNGIDAIAAIKRRSPGIR
IIALSVHQNDEYVREALRAGVDGYVLKDTSFDDLVTAMRVVLLGKKHLSPELYGNLVESYVSGHEMSTAKTGWDLLTARE
RSVLKLVAEGRSNRQVGIYMNLSPKTIEKYRASLMRKLGITNLTELVLIAISMGLITSLARKYCDDNHPSVTNHDGLDAV
PLPAVRRQMLDEGRAAGSDGEASP

Sequences:

>Translated_264_residues
MNNNCSVLIVEDHNLLRAGLRSMLSAQMGYHVAGEARDGREACQLAISLCPDLILMDLSLPGMNGIDAIAAIKRRSPGIR
IIALSVHQNDEYVREALRAGVDGYVLKDTSFDDLVTAMRVVLLGKKHLSPELYGNLVESYVSGHEMSTAKTGWDLLTARE
RSVLKLVAEGRSNRQVGIYMNLSPKTIEKYRASLMRKLGITNLTELVLIAISMGLITSLARKYCDDNHPSVTNHDGLDAV
PLPAVRRQMLDEGRAAGSDGEASP
>Mature_264_residues
MNNNCSVLIVEDHNLLRAGLRSMLSAQMGYHVAGEARDGREACQLAISLCPDLILMDLSLPGMNGIDAIAAIKRRSPGIR
IIALSVHQNDEYVREALRAGVDGYVLKDTSFDDLVTAMRVVLLGKKHLSPELYGNLVESYVSGHEMSTAKTGWDLLTARE
RSVLKLVAEGRSNRQVGIYMNLSPKTIEKYRASLMRKLGITNLTELVLIAISMGLITSLARKYCDDNHPSVTNHDGLDAV
PLPAVRRQMLDEGRAAGSDGEASP

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=210, Percent_Identity=31.9047619047619, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1788521, Length=197, Percent_Identity=36.5482233502538, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1787473, Length=186, Percent_Identity=35.4838709677419, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790102, Length=201, Percent_Identity=31.8407960199005, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788546, Length=203, Percent_Identity=32.512315270936, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1786747, Length=202, Percent_Identity=25.7425742574257, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788712, Length=205, Percent_Identity=26.8292682926829, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 28812; Mature: 28812

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNNCSVLIVEDHNLLRAGLRSMLSAQMGYHVAGEARDGREACQLAISLCPDLILMDLSL
CCCCCEEEEECCCHHHHHHHHHHHHHHHCCEECCCCCCHHHHHHHHHHHHHHHHEEECCC
PGMNGIDAIAAIKRRSPGIRIIALSVHQNDEYVREALRAGVDGYVLKDTSFDDLVTAMRV
CCCCCHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHCCCCCEEECCCCHHHHHHHHHH
VLLGKKHLSPELYGNLVESYVSGHEMSTAKTGWDLLTARERSVLKLVAEGRSNRQVGIYM
HHHHHHHCCHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEEE
NLSPKTIEKYRASLMRKLGITNLTELVLIAISMGLITSLARKYCDDNHPSVTNHDGLDAV
ECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
PLPAVRRQMLDEGRAAGSDGEASP
CCHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNNNCSVLIVEDHNLLRAGLRSMLSAQMGYHVAGEARDGREACQLAISLCPDLILMDLSL
CCCCCEEEEECCCHHHHHHHHHHHHHHHCCEECCCCCCHHHHHHHHHHHHHHHHEEECCC
PGMNGIDAIAAIKRRSPGIRIIALSVHQNDEYVREALRAGVDGYVLKDTSFDDLVTAMRV
CCCCCHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHCCCCCEEECCCCHHHHHHHHHH
VLLGKKHLSPELYGNLVESYVSGHEMSTAKTGWDLLTARERSVLKLVAEGRSNRQVGIYM
HHHHHHHCCHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEEE
NLSPKTIEKYRASLMRKLGITNLTELVLIAISMGLITSLARKYCDDNHPSVTNHDGLDAV
ECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
PLPAVRRQMLDEGRAAGSDGEASP
CCHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]