Click here to switch to the map view.

The map label for this gene is comE [H]

Identifier: 94313628

GI number: 94313628

Start: 1348369

End: 1350573

Strand: Reverse

Name: comE [H]

Synonym: Rmet_4706

Alternate gene names: 94313628

Gene position: 1350573-1348369 (Counterclockwise)

Preceding gene: 94313629

Following gene: 94313627

Centisome position: 52.35

GC content: 64.58

Gene sequence:

>2205_bases
ATGCATACCTCACGTGGGCCCAGGCTGATCCGGGCGAGATGCAAAGCGCAGCCCATCTGCATCGGCGTCATCCTGTTGGG
AACCTGCCTTGCCGGTTGCTCGCCCATGTACCAGCGATTCCCGCCGGACCCGAGCACCAATGCAGAGCAGATCGTCGGCG
CGCTGCGCGAGCGGGACAGGCAGGTCAATGCACTGCTCGAGGAGGCGGAGCGACTACGCGCGGCAGGCCAGTACCAGGAC
GCCGTTCCGCTGCTTGGCGCGGCGAACCAGCTGGACCCCACCAACGAGCGCGCGCGCATTCTTGGCGCGGCGCTGCAGCG
TGACTGGCGCGACGCGGCCATCCTGCAGGAAGCGGAGCGTATGTTCGATCGTGGCTCCTACGATATTGCAGCGGAGCGCG
TCCGCTACGTGCTTGCCGAGAATCCGAACAGCATTGCCGGCAGACAACTGGCCCAGCGTATCGAGGAGCAACGCCGTCTG
CTGCGGCTTGCGCGTGAGGAACAGCGCGCGGCGGGGTCCATCATGCGCACGCCGGTGACCCTGCAGTTCCGCGATGCCAA
CATCCGCATGGTGTTCGAAGCACTATCCCGTACCTCCGGTCTCAATGTCATCTTCGACCGGGATGTGCGTGCCGATCTCA
AGACCACGATTTTCGTGACCAATGCGGCAATCGAGGACGCGGTGGATCTGATCCTGCTGCAAAGCCAGCTCGACAAGAAG
GTGCTGAACGCCAACACGCTGTTCATCTACCCAGCCACGCCCGCCAAGCAGCAGGAGTATCAGGAGCTCAAGGTCCGCAC
ATTCCAGCTGTCGAATGTCGACTCCAAGCAGGTCCAGTCGCTGCTGAAGAGTCTGCTGAAGATCAAGGAAGTCGTGGTCG
ACGAACGCGCGAACACCGTGACCATTCGCGGTACGCCAGACACGATTCGCGTGGCGGAGCAGATGATCGCCGCGCAGGAC
CTGCCGGAGCCGGAAGTCATGCTCGAAGTCCAGGTTCTGGAGGTGTCGCGCGAGCGTCTGACCGACCTTGGCATCGCATG
GCCAAATTCGTTCACGATGGCCACACCAGCCTCTGCGACGACATGGGGCGTGCTGCACCACCTGACCGCCAACGAGCTTG
AAGTGAGTCCGTTGTCGGCGACAGCCAACTTCAAGCTGACCGATACCGATGCCAATCTGCTCGCCAGCCCGCGGATTCGT
ACGCGAAACAAGGAGAAGGCAAGGATCCTGATTGGCGACAAGGTGCCGGTGATCTCCAGTTCCAGCACGCCCAGCACGAG
CGGACCATCGTTCACCCAGACGATCCAGTATCTGGATGTCGGCATCAAGCTGGAAGTGGAGCCCCAGGTGTATCGCGACA
ACGACGTGGGCATCAAACTGGCCCTGGAGGTCAGCAATATCACCAAGACGATCCAGAGCGGCAACGCGCAGACGGGCCTG
AGTTCGCTGGCTTACCAGATTGGCACGCGCAGCGCGTCCACGAGCCTGCGACTGCGGGACGGCGAAACGCAGATACTCGG
CGGGCTGATCTCGGATCAGGATCGGACGTCTGCCGACAAGGTGCCCGGGCTGGGGCAGTTGCCGGTGGTTGGGAGGCTGT
TCTCCGACCACAATGGTGACCACGTCAAGACCGAGATCGTGCTGCAGATCACGCCGCATATCGTACGCCCGCAACTGACG
ATGGATAGCGACACGCGCGAGCTCTGGTCCGGCACCGATACCAATGTCCGCACCGAACAATTGCGGCTGGACCCGAGCCG
TCCCGTCGCATCGACGGCATCCGGCGCGCCTGCGTTGCCCTATACGCCGGTCAAGCCTGGACAGGTAGGTGGCGGAACCA
TGGGGCCGCCACCGGCCGCAAGCGGCAGCGCTGCAGCAACGCCAAAGAGTGCATTCGGGCAGCCTCCGCCGCCGATGCGG
ACCACGCCGCCACCGGCTCCCTATAACGGTCGCTTCTCGGGCACGCCTGCGGTGCCGCAGGGGCAGGCAGCGCCAGCCGG
CACAGCCGAGCCGGCGCCGCCACCACCCGTGCCGGCGTCTGGCAACGCCGACGGCTCGGCCGAAAATACGGCGCCGCCGC
CAGCGCCACGTGGTCCGGTGCAGGTGGAGCTGATTCCACCGACGCCGCCCGCGCCAATGCCCCGGCAGCCGACGGACATC
CCCAGCGACAATCCGCTGTACTCGATCCCCGGCGGCAGCCCCTGA

Upstream 100 bases:

>100_bases
GCAGTACCGTATCGACGCGATTGCGACCGAGAGCATCACGTTTACCTACCTGCCGCTCAATATGAAGCAGGTCCTGCCCA
CCCAGAGCGAGGGGAAATAA

Downstream 100 bases:

>100_bases
ACCATGAATGCCAGGCCCGGATCTCTCTGCATTGCGCGTCGCGGCCCGCTGACGGGATGCGGGGGGCGCGGCTTCACGCT
GATCGAGCTGGTGGTGACCC

Product: putative secretion type II protein; gspD(secretin)-like protein

Products: NA

Alternate protein names: DNA transformation protein ComE [H]

Number of amino acids: Translated: 734; Mature: 734

Protein sequence:

>734_residues
MHTSRGPRLIRARCKAQPICIGVILLGTCLAGCSPMYQRFPPDPSTNAEQIVGALRERDRQVNALLEEAERLRAAGQYQD
AVPLLGAANQLDPTNERARILGAALQRDWRDAAILQEAERMFDRGSYDIAAERVRYVLAENPNSIAGRQLAQRIEEQRRL
LRLAREEQRAAGSIMRTPVTLQFRDANIRMVFEALSRTSGLNVIFDRDVRADLKTTIFVTNAAIEDAVDLILLQSQLDKK
VLNANTLFIYPATPAKQQEYQELKVRTFQLSNVDSKQVQSLLKSLLKIKEVVVDERANTVTIRGTPDTIRVAEQMIAAQD
LPEPEVMLEVQVLEVSRERLTDLGIAWPNSFTMATPASATTWGVLHHLTANELEVSPLSATANFKLTDTDANLLASPRIR
TRNKEKARILIGDKVPVISSSSTPSTSGPSFTQTIQYLDVGIKLEVEPQVYRDNDVGIKLALEVSNITKTIQSGNAQTGL
SSLAYQIGTRSASTSLRLRDGETQILGGLISDQDRTSADKVPGLGQLPVVGRLFSDHNGDHVKTEIVLQITPHIVRPQLT
MDSDTRELWSGTDTNVRTEQLRLDPSRPVASTASGAPALPYTPVKPGQVGGGTMGPPPAASGSAAATPKSAFGQPPPPMR
TTPPPAPYNGRFSGTPAVPQGQAAPAGTAEPAPPPPVPASGNADGSAENTAPPPAPRGPVQVELIPPTPPAPMPRQPTDI
PSDNPLYSIPGGSP

Sequences:

>Translated_734_residues
MHTSRGPRLIRARCKAQPICIGVILLGTCLAGCSPMYQRFPPDPSTNAEQIVGALRERDRQVNALLEEAERLRAAGQYQD
AVPLLGAANQLDPTNERARILGAALQRDWRDAAILQEAERMFDRGSYDIAAERVRYVLAENPNSIAGRQLAQRIEEQRRL
LRLAREEQRAAGSIMRTPVTLQFRDANIRMVFEALSRTSGLNVIFDRDVRADLKTTIFVTNAAIEDAVDLILLQSQLDKK
VLNANTLFIYPATPAKQQEYQELKVRTFQLSNVDSKQVQSLLKSLLKIKEVVVDERANTVTIRGTPDTIRVAEQMIAAQD
LPEPEVMLEVQVLEVSRERLTDLGIAWPNSFTMATPASATTWGVLHHLTANELEVSPLSATANFKLTDTDANLLASPRIR
TRNKEKARILIGDKVPVISSSSTPSTSGPSFTQTIQYLDVGIKLEVEPQVYRDNDVGIKLALEVSNITKTIQSGNAQTGL
SSLAYQIGTRSASTSLRLRDGETQILGGLISDQDRTSADKVPGLGQLPVVGRLFSDHNGDHVKTEIVLQITPHIVRPQLT
MDSDTRELWSGTDTNVRTEQLRLDPSRPVASTASGAPALPYTPVKPGQVGGGTMGPPPAASGSAAATPKSAFGQPPPPMR
TTPPPAPYNGRFSGTPAVPQGQAAPAGTAEPAPPPPVPASGNADGSAENTAPPPAPRGPVQVELIPPTPPAPMPRQPTDI
PSDNPLYSIPGGSP
>Mature_734_residues
MHTSRGPRLIRARCKAQPICIGVILLGTCLAGCSPMYQRFPPDPSTNAEQIVGALRERDRQVNALLEEAERLRAAGQYQD
AVPLLGAANQLDPTNERARILGAALQRDWRDAAILQEAERMFDRGSYDIAAERVRYVLAENPNSIAGRQLAQRIEEQRRL
LRLAREEQRAAGSIMRTPVTLQFRDANIRMVFEALSRTSGLNVIFDRDVRADLKTTIFVTNAAIEDAVDLILLQSQLDKK
VLNANTLFIYPATPAKQQEYQELKVRTFQLSNVDSKQVQSLLKSLLKIKEVVVDERANTVTIRGTPDTIRVAEQMIAAQD
LPEPEVMLEVQVLEVSRERLTDLGIAWPNSFTMATPASATTWGVLHHLTANELEVSPLSATANFKLTDTDANLLASPRIR
TRNKEKARILIGDKVPVISSSSTPSTSGPSFTQTIQYLDVGIKLEVEPQVYRDNDVGIKLALEVSNITKTIQSGNAQTGL
SSLAYQIGTRSASTSLRLRDGETQILGGLISDQDRTSADKVPGLGQLPVVGRLFSDHNGDHVKTEIVLQITPHIVRPQLT
MDSDTRELWSGTDTNVRTEQLRLDPSRPVASTASGAPALPYTPVKPGQVGGGTMGPPPAASGSAAATPKSAFGQPPPPMR
TTPPPAPYNGRFSGTPAVPQGQAAPAGTAEPAPPPPVPASGNADGSAENTAPPPAPRGPVQVELIPPTPPAPMPRQPTDI
PSDNPLYSIPGGSP

Specific function: Involved in transformation (competence for DNA uptake) [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=405, Percent_Identity=23.2098765432099, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI87082242, Length=333, Percent_Identity=27.027027027027, Blast_Score=87, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR004846
- InterPro:   IPR004845
- InterPro:   IPR001814 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N [H]

EC number: NA

Molecular weight: Translated: 79206; Mature: 79206

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTSRGPRLIRARCKAQPICIGVILLGTCLAGCSPMYQRFPPDPSTNAEQIVGALRERDR
CCCCCCCHHHHHHHCCCCCEEHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHH
QVNALLEEAERLRAAGQYQDAVPLLGAANQLDPTNERARILGAALQRDWRDAAILQEAER
HHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MFDRGSYDIAAERVRYVLAENPNSIAGRQLAQRIEEQRRLLRLAREEQRAAGSIMRTPVT
HHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCEE
LQFRDANIRMVFEALSRTSGLNVIFDRDVRADLKTTIFVTNAAIEDAVDLILLQSQLDKK
EEEECCCHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHH
VLNANTLFIYPATPAKQQEYQELKVRTFQLSNVDSKQVQSLLKSLLKIKEVVVDERANTV
HHCCCEEEEEECCCCCHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEE
TIRGTPDTIRVAEQMIAAQDLPEPEVMLEVQVLEVSRERLTDLGIAWPNSFTMATPASAT
EEECCCHHHHHHHHHHHHHCCCCCHHEEEEHHHHHHHHHHHHCCCCCCCCCEEECCCCCH
TWGVLHHLTANELEVSPLSATANFKLTDTDANLLASPRIRTRNKEKARILIGDKVPVISS
HHHHHHHCCCCCEEECCCCCEEEEEEECCCCCCEECCCCCCCCCCCEEEEECCCCCEEEC
SSTPSTSGPSFTQTIQYLDVGIKLEVEPQVYRDNDVGIKLALEVSNITKTIQSGNAQTGL
CCCCCCCCCHHHHHHHHHCCCEEEEECCCEEECCCCCEEEEEEHHHHHHHHHCCCCHHHH
SSLAYQIGTRSASTSLRLRDGETQILGGLISDQDRTSADKVPGLGQLPVVGRLFSDHNGD
HHHHHHHCCCCCCCEEEEECCCHHHHHHHHCCCCCCCHHCCCCCCCCCHHHHHHCCCCCC
HVKTEIVLQITPHIVRPQLTMDSDTRELWSGTDTNVRTEQLRLDPSRPVASTASGAPALP
EEEEEEEEEECCCCCCCCEECCCCHHHHHCCCCCCCEEHEEECCCCCCCCCCCCCCCCCC
YTPVKPGQVGGGTMGPPPAASGSAAATPKSAFGQPPPPMRTTPPPAPYNGRFSGTPAVPQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GQAAPAGTAEPAPPPPVPASGNADGSAENTAPPPAPRGPVQVELIPPTPPAPMPRQPTDI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCC
PSDNPLYSIPGGSP
CCCCCEEECCCCCC
>Mature Secondary Structure
MHTSRGPRLIRARCKAQPICIGVILLGTCLAGCSPMYQRFPPDPSTNAEQIVGALRERDR
CCCCCCCHHHHHHHCCCCCEEHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHH
QVNALLEEAERLRAAGQYQDAVPLLGAANQLDPTNERARILGAALQRDWRDAAILQEAER
HHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MFDRGSYDIAAERVRYVLAENPNSIAGRQLAQRIEEQRRLLRLAREEQRAAGSIMRTPVT
HHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCEE
LQFRDANIRMVFEALSRTSGLNVIFDRDVRADLKTTIFVTNAAIEDAVDLILLQSQLDKK
EEEECCCHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHH
VLNANTLFIYPATPAKQQEYQELKVRTFQLSNVDSKQVQSLLKSLLKIKEVVVDERANTV
HHCCCEEEEEECCCCCHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEE
TIRGTPDTIRVAEQMIAAQDLPEPEVMLEVQVLEVSRERLTDLGIAWPNSFTMATPASAT
EEECCCHHHHHHHHHHHHHCCCCCHHEEEEHHHHHHHHHHHHCCCCCCCCCEEECCCCCH
TWGVLHHLTANELEVSPLSATANFKLTDTDANLLASPRIRTRNKEKARILIGDKVPVISS
HHHHHHHCCCCCEEECCCCCEEEEEEECCCCCCEECCCCCCCCCCCEEEEECCCCCEEEC
SSTPSTSGPSFTQTIQYLDVGIKLEVEPQVYRDNDVGIKLALEVSNITKTIQSGNAQTGL
CCCCCCCCCHHHHHHHHHCCCEEEEECCCEEECCCCCEEEEEEHHHHHHHHHCCCCHHHH
SSLAYQIGTRSASTSLRLRDGETQILGGLISDQDRTSADKVPGLGQLPVVGRLFSDHNGD
HHHHHHHCCCCCCCEEEEECCCHHHHHHHHCCCCCCCHHCCCCCCCCCHHHHHHCCCCCC
HVKTEIVLQITPHIVRPQLTMDSDTRELWSGTDTNVRTEQLRLDPSRPVASTASGAPALP
EEEEEEEEEECCCCCCCCEECCCCHHHHHCCCCCCCEEHEEECCCCCCCCCCCCCCCCCC
YTPVKPGQVGGGTMGPPPAASGSAAATPKSAFGQPPPPMRTTPPPAPYNGRFSGTPAVPQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GQAAPAGTAEPAPPPPVPASGNADGSAENTAPPPAPRGPVQVELIPPTPPAPMPRQPTDI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCC
PSDNPLYSIPGGSP
CCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1916268; 7542800; 1856167 [H]