Click here to switch to the map view.

The map label for this gene is nodT [H]

Identifier: 94313571

GI number: 94313571

Start: 1279530

End: 1281017

Strand: Reverse

Name: nodT [H]

Synonym: Rmet_4649

Alternate gene names: 94313571

Gene position: 1281017-1279530 (Counterclockwise)

Preceding gene: 94313576

Following gene: 94313570

Centisome position: 49.65

GC content: 66.06

Gene sequence:

>1488_bases
ATGGCATCGAAAGCACTTCCCGGCACCCATGCCCAAGGACTGGTTAAACGTACCGCGCGCGCCGTGGCCCTGGCCGCCGC
CACACTCGCTGCACTGGGCATGGCCGCCTGCGCGGTCGGCCCTGACTACCGCACGCCGGATAGCGAGATGCCGACGCAGT
ACCAGCACGCCGCCGACGTGGCAGCGATCAACGACGCGCGCGAACCGGTGGCGCTGGATACGTGGTGGGCCGGCTTCCAG
GACCCGGTGCTGACAAAGATCGTCGAGCGGGCCCTTGAACAGAATCTCGACATGGCGGCGTCAATTGCCCGCGTGGCGCA
GGCCCGTGCCGCCGCCAACTTCGCTGGGGCCGAGTTGCTTCCGCAAGGCAATGCCTATAGCGACGTGACCAAGCTGCATC
AATCCGTACAAAGCCCGCTGGGCAAGATCGGCAGCACATTCCCCGGATATGACCGCAACCAGACGCTCTATTCGGTGGGC
GCTGCGGCCACGTGGGAAATCGACATCGCTGGCGGGCTGCGGCGCGGTGCCGAGGCGGCCAATGCCGAACTGCAGGCGGC
AGAGGCGAACCACATGGGCGTTCGGATTCTCGTGGCAGCGGAGGCGGCGGACGCCTACTTCCGTGTGCGGGGGGCTCAGG
CTCGCATCGCCATCGCGCAGCAACAGGTCGAGACCAACCAGCGCCTGCTTGATCTCGTGCGTTTGCGGTTGGCCGATGGC
ATCGGGGCGGAGCGCGAGCAGGCGCAGGCCGAGGCCCAACTCTCGCAGACGCGCGTCACGATTCCGCCGCTGCAGATCGA
ACTGGAAACGCAGCTTAATCGCCTCGACGTCCTGATGGGCGCGCAACCGGGCACCTACGCAGCCGAGTTGCGCGATTCGA
AGCACGAAACGCAGGCGGTGCCACAAGTCGCCTTGGCACAGGGTCCGGCAAACCTGCTGGAACGTCGCCCAGACGTCATT
GCCGCCGAACGCAGGCTTGCGGCGTCGAGTGCGCGCATTGGCGTGGCCACGGCGGAGTACTACCCGAAGGTTTCGCTATC
GGCATTGCTTGGATTCGAAAGCCTGTCCGCCGGCAAGCTGTTCACCGCGCAGGCCTTCCAGCCTGCGGCGGCGGCTGGGC
TGCGCTGGCGGCTGTTCGATTTCGGCCGGGTCAATGCGGAAGTCGCGCAGGCCAAGGGCGCCAATGCCGAAGCGTTGGCC
AGCTATCGCAAGTCGATGCTGCAGGCCACCGAGGACGTCGAAAACGCATTGATCTCGCTGGCGCAGCTCGAATCGCAAAA
CCGCGAACTGGCCGTAGAGATCCGTGCGCATGAGCGCGCGCGAAACGCATCCGAGGATGCCTACAAGGGCGGGGTGGTCA
GCCTCTATGAAGTGCTGGACGAAGACCGGCAATTGCTGGCTGCACGCGACCAGCAGGCAAGGGTGCAGGCGGATAATGCA
CGGGCGGCGGTGTCGGCGTTCCGGGCGCTGGGAGGTGGATGGTCCTGA

Upstream 100 bases:

>100_bases
ACGTTGCTATCAATATGAAAGTTAGTCTAGGCTAGCAACTATCATCATGCAAGAAACAGTTTCGAGAACCGCTGCATGAG
AACTGACGAAAGGAATCGAG

Downstream 100 bases:

>100_bases
GCCCTGGGACGCGCCTCGCCTTCATGCTCAAAAAGCGGATCAATAGACATTTTGATGCCTCATCCAGACGATTTGCGGGG
AATGACAGCAATATTCACCG

Product: RND efflux system outer membrane lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MASKALPGTHAQGLVKRTARAVALAAATLAALGMAACAVGPDYRTPDSEMPTQYQHAADVAAINDAREPVALDTWWAGFQ
DPVLTKIVERALEQNLDMAASIARVAQARAAANFAGAELLPQGNAYSDVTKLHQSVQSPLGKIGSTFPGYDRNQTLYSVG
AAATWEIDIAGGLRRGAEAANAELQAAEANHMGVRILVAAEAADAYFRVRGAQARIAIAQQQVETNQRLLDLVRLRLADG
IGAEREQAQAEAQLSQTRVTIPPLQIELETQLNRLDVLMGAQPGTYAAELRDSKHETQAVPQVALAQGPANLLERRPDVI
AAERRLAASSARIGVATAEYYPKVSLSALLGFESLSAGKLFTAQAFQPAAAAGLRWRLFDFGRVNAEVAQAKGANAEALA
SYRKSMLQATEDVENALISLAQLESQNRELAVEIRAHERARNASEDAYKGGVVSLYEVLDEDRQLLAARDQQARVQADNA
RAAVSAFRALGGGWS

Sequences:

>Translated_495_residues
MASKALPGTHAQGLVKRTARAVALAAATLAALGMAACAVGPDYRTPDSEMPTQYQHAADVAAINDAREPVALDTWWAGFQ
DPVLTKIVERALEQNLDMAASIARVAQARAAANFAGAELLPQGNAYSDVTKLHQSVQSPLGKIGSTFPGYDRNQTLYSVG
AAATWEIDIAGGLRRGAEAANAELQAAEANHMGVRILVAAEAADAYFRVRGAQARIAIAQQQVETNQRLLDLVRLRLADG
IGAEREQAQAEAQLSQTRVTIPPLQIELETQLNRLDVLMGAQPGTYAAELRDSKHETQAVPQVALAQGPANLLERRPDVI
AAERRLAASSARIGVATAEYYPKVSLSALLGFESLSAGKLFTAQAFQPAAAAGLRWRLFDFGRVNAEVAQAKGANAEALA
SYRKSMLQATEDVENALISLAQLESQNRELAVEIRAHERARNASEDAYKGGVVSLYEVLDEDRQLLAARDQQARVQADNA
RAAVSAFRALGGGWS
>Mature_494_residues
ASKALPGTHAQGLVKRTARAVALAAATLAALGMAACAVGPDYRTPDSEMPTQYQHAADVAAINDAREPVALDTWWAGFQD
PVLTKIVERALEQNLDMAASIARVAQARAAANFAGAELLPQGNAYSDVTKLHQSVQSPLGKIGSTFPGYDRNQTLYSVGA
AATWEIDIAGGLRRGAEAANAELQAAEANHMGVRILVAAEAADAYFRVRGAQARIAIAQQQVETNQRLLDLVRLRLADGI
GAEREQAQAEAQLSQTRVTIPPLQIELETQLNRLDVLMGAQPGTYAAELRDSKHETQAVPQVALAQGPANLLERRPDVIA
AERRLAASSARIGVATAEYYPKVSLSALLGFESLSAGKLFTAQAFQPAAAAGLRWRLFDFGRVNAEVAQAKGANAEALAS
YRKSMLQATEDVENALISLAQLESQNRELAVEIRAHERARNASEDAYKGGVVSLYEVLDEDRQLLAARDQQARVQADNAR
AAVSAFRALGGGWS

Specific function: In Pathogenic Strains It Allows The Bacteria To Invade Brain Microvascular Endothelial Cells (Bmec) Thus Allowing It To Cross The Blood-Brain Barrier And Cause Neonatal Meningitis. [C]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=470, Percent_Identity=27.2340425531915, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI2367348, Length=492, Percent_Identity=23.780487804878, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 52806; Mature: 52675

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASKALPGTHAQGLVKRTARAVALAAATLAALGMAACAVGPDYRTPDSEMPTQYQHAADV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
AAINDAREPVALDTWWAGFQDPVLTKIVERALEQNLDMAASIARVAQARAAANFAGAELL
HHHCCCCCCCEEEHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHC
PQGNAYSDVTKLHQSVQSPLGKIGSTFPGYDRNQTLYSVGAAATWEIDIAGGLRRGAEAA
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCEEEEEEECCCHHCCCHHH
NAELQAAEANHMGVRILVAAEAADAYFRVRGAQARIAIAQQQVETNQRLLDLVRLRLADG
CCHHEECCCCCCCEEEEEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IGAEREQAQAEAQLSQTRVTIPPLQIELETQLNRLDVLMGAQPGTYAAELRDSKHETQAV
CCCHHHHHHHHHHHHHCEEECCCEEEEHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHH
PQVALAQGPANLLERRPDVIAAERRLAASSARIGVATAEYYPKVSLSALLGFESLSAGKL
HHHHHHCCCHHHHHCCCCHHHHHHHHHHCCCCCEEEEHHHCCCHHHHHHHHHHHCCCCCE
FTAQAFQPAAAAGLRWRLFDFGRVNAEVAQAKGANAEALASYRKSMLQATEDVENALISL
EEHHCCCCHHHCCCEEEEEECCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AQLESQNRELAVEIRAHERARNASEDAYKGGVVSLYEVLDEDRQLLAARDQQARVQADNA
HHHHCCCCEEEEEEEHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCHH
RAAVSAFRALGGGWS
HHHHHHHHHHCCCCC
>Mature Secondary Structure 
ASKALPGTHAQGLVKRTARAVALAAATLAALGMAACAVGPDYRTPDSEMPTQYQHAADV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
AAINDAREPVALDTWWAGFQDPVLTKIVERALEQNLDMAASIARVAQARAAANFAGAELL
HHHCCCCCCCEEEHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHC
PQGNAYSDVTKLHQSVQSPLGKIGSTFPGYDRNQTLYSVGAAATWEIDIAGGLRRGAEAA
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCEEEEEEECCCHHCCCHHH
NAELQAAEANHMGVRILVAAEAADAYFRVRGAQARIAIAQQQVETNQRLLDLVRLRLADG
CCHHEECCCCCCCEEEEEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IGAEREQAQAEAQLSQTRVTIPPLQIELETQLNRLDVLMGAQPGTYAAELRDSKHETQAV
CCCHHHHHHHHHHHHHCEEECCCEEEEHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHH
PQVALAQGPANLLERRPDVIAAERRLAASSARIGVATAEYYPKVSLSALLGFESLSAGKL
HHHHHHCCCHHHHHCCCCHHHHHHHHHHCCCCCEEEEHHHCCCHHHHHHHHHHHCCCCCE
FTAQAFQPAAAAGLRWRLFDFGRVNAEVAQAKGANAEALASYRKSMLQATEDVENALISL
EEHHCCCCHHHCCCEEEEEECCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AQLESQNRELAVEIRAHERARNASEDAYKGGVVSLYEVLDEDRQLLAARDQQARVQADNA
HHHHCCCCEEEEEEEHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCHH
RAAVSAFRALGGGWS
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2303029; 2338917 [H]