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The map label for this gene is fabG [H]

Identifier: 94313568

GI number: 94313568

Start: 1276200

End: 1277153

Strand: Reverse

Name: fabG [H]

Synonym: Rmet_4646

Alternate gene names: 94313568

Gene position: 1277153-1276200 (Counterclockwise)

Preceding gene: 94313570

Following gene: 94313567

Centisome position: 49.5

GC content: 65.72

Gene sequence:

>954_bases
ATGAAAACGTTCCACAGTTGGACGCCGATTTCCTTGCTGGGTAAATTAATACCACACGGAAAACGATTCCACATCTGGAA
CTACAACGGAGACAACATGACCACGACACGCCCGATCCATCCGGAAGTGCAATGTTTTGACGAGGCGCTGGGACAAACCC
CGCCCGCTGGCGGCCGACTGGCGGGGCGTCGCATTCTCGTCGTCGGGGCCGGACAGCGCGTCATCGATGATCCGGACCCG
CCCGTCGGCAACGGCCGCGCGATCTCGCTGCTGTTTGCGCGGGAAGGCGCCACGCTGACCTGCGTCGATATTTCCGAACC
CGCCGTGGCGGAGACCTGCAGGCAGGCGAAGGACCTGGGTGCGACCGTCTTTGCCGAGGTGGCCGATGTCGAACGCGCCG
AGACCATCGCACCGCTAGTCGAGCGCGCAGCTCGTCAGATGGGAGGTCTCGACGGCCTGGTCATGGTGGTGGGCATCTCC
AGCGCCTTGCCGATCGATAAGCAGGACGCCAATACGTGGGACCGCGAGTACGCCGTCAACGTGCGCAGCAACATGCTGTT
CGCGCAGCAGGCCATGCGCCATATGGAGCCGGGTAGTTCCATCGTGCTGATGTCCTCGCTGGCTGCCTTGCGCAACAGCA
GCGGCAACCCGGCCTATGAGTCGTCGAAGGCCGCCCAGGTGGCGCTGGCGCGTTCCATTGCGATGGCCGGGCAGAAGCAG
GGCATCCGCTGCAACAGCCTGTTGCCGGGACTCATGGACACGCCGATGGGCCGTGCCGCCACCGCGCGACGGCCCGCGCG
CGTCGGTGGGGCGCTGCCGTTCGGCCGGCAGGGCACCGGCTGGGAGGTGGCGTATGCGTGCCTGTTCCTGATGTCGCACG
AATCGTCGTACGTCAACGCGCACGCGTTGCAGGTGGACGGCGGACTGGCCGCCGGTGTGGCCCTGACGGCCTGA

Upstream 100 bases:

>100_bases
TAGCCGTTGCCGTTCAGGACGCGCGACACACTACCGACCGATACCCCCGCCGCCTGCGCCACATCGCGCACAGAAGCCTT
TCCCGTCATGGTCTTCCCTA

Downstream 100 bases:

>100_bases
GGAGCGCTGCATGGATGCATCTCTTGTTCATGCGCGGCCGCGCCGGTTGCGCCCGTTACGACCACTACGCCCGTTGCCTG
CCCTGTTGCCGACGGCCTTG

Product: short-chain dehydrogenase; putative 3-oxoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MKTFHSWTPISLLGKLIPHGKRFHIWNYNGDNMTTTRPIHPEVQCFDEALGQTPPAGGRLAGRRILVVGAGQRVIDDPDP
PVGNGRAISLLFAREGATLTCVDISEPAVAETCRQAKDLGATVFAEVADVERAETIAPLVERAARQMGGLDGLVMVVGIS
SALPIDKQDANTWDREYAVNVRSNMLFAQQAMRHMEPGSSIVLMSSLAALRNSSGNPAYESSKAAQVALARSIAMAGQKQ
GIRCNSLLPGLMDTPMGRAATARRPARVGGALPFGRQGTGWEVAYACLFLMSHESSYVNAHALQVDGGLAAGVALTA

Sequences:

>Translated_317_residues
MKTFHSWTPISLLGKLIPHGKRFHIWNYNGDNMTTTRPIHPEVQCFDEALGQTPPAGGRLAGRRILVVGAGQRVIDDPDP
PVGNGRAISLLFAREGATLTCVDISEPAVAETCRQAKDLGATVFAEVADVERAETIAPLVERAARQMGGLDGLVMVVGIS
SALPIDKQDANTWDREYAVNVRSNMLFAQQAMRHMEPGSSIVLMSSLAALRNSSGNPAYESSKAAQVALARSIAMAGQKQ
GIRCNSLLPGLMDTPMGRAATARRPARVGGALPFGRQGTGWEVAYACLFLMSHESSYVNAHALQVDGGLAAGVALTA
>Mature_317_residues
MKTFHSWTPISLLGKLIPHGKRFHIWNYNGDNMTTTRPIHPEVQCFDEALGQTPPAGGRLAGRRILVVGAGQRVIDDPDP
PVGNGRAISLLFAREGATLTCVDISEPAVAETCRQAKDLGATVFAEVADVERAETIAPLVERAARQMGGLDGLVMVVGIS
SALPIDKQDANTWDREYAVNVRSNMLFAQQAMRHMEPGSSIVLMSSLAALRNSSGNPAYESSKAAQVALARSIAMAGQKQ
GIRCNSLLPGLMDTPMGRAATARRPARVGGALPFGRQGTGWEVAYACLFLMSHESSYVNAHALQVDGGLAAGVALTA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=230, Percent_Identity=31.7391304347826, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI15277342, Length=262, Percent_Identity=29.7709923664122, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI66933014, Length=231, Percent_Identity=30.7359307359307, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI32483357, Length=231, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI5031737, Length=232, Percent_Identity=28.8793103448276, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI33667109, Length=228, Percent_Identity=28.5087719298246, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI40807363, Length=219, Percent_Identity=25.1141552511416, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI7705925, Length=258, Percent_Identity=27.1317829457364, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI4504505, Length=202, Percent_Identity=26.7326732673267, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1789208, Length=246, Percent_Identity=29.2682926829268, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1789378, Length=256, Percent_Identity=28.90625, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI87082100, Length=262, Percent_Identity=30.1526717557252, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786812, Length=265, Percent_Identity=30.9433962264151, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790717, Length=259, Percent_Identity=27.7992277992278, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787335, Length=229, Percent_Identity=27.0742358078603, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787905, Length=253, Percent_Identity=29.2490118577075, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI2367175, Length=236, Percent_Identity=28.8135593220339, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI2367365, Length=258, Percent_Identity=29.0697674418605, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1788459, Length=233, Percent_Identity=25.3218884120172, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=261, Percent_Identity=30.6513409961686, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI25147288, Length=256, Percent_Identity=29.296875, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17555706, Length=230, Percent_Identity=32.1739130434783, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=239, Percent_Identity=28.8702928870293, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=247, Percent_Identity=31.1740890688259, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17561402, Length=238, Percent_Identity=26.890756302521, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=271, Percent_Identity=28.4132841328413, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=273, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=267, Percent_Identity=25.8426966292135, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=236, Percent_Identity=27.1186440677966, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=278, Percent_Identity=25.5395683453237, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=248, Percent_Identity=28.6290322580645, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=270, Percent_Identity=27.037037037037, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=273, Percent_Identity=27.8388278388278, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24639444, Length=259, Percent_Identity=33.5907335907336, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24643142, Length=252, Percent_Identity=30.952380952381, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21355319, Length=234, Percent_Identity=28.6324786324786, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI281364892, Length=224, Percent_Identity=28.125, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI23397609, Length=256, Percent_Identity=28.515625, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21357041, Length=236, Percent_Identity=30.9322033898305, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI17737361, Length=241, Percent_Identity=28.2157676348548, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24640492, Length=222, Percent_Identity=24.3243243243243, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24644337, Length=226, Percent_Identity=28.3185840707965, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28571526, Length=234, Percent_Identity=29.0598290598291, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 33672; Mature: 33672

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTFHSWTPISLLGKLIPHGKRFHIWNYNGDNMTTTRPIHPEVQCFDEALGQTPPAGGRL
CCCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCEECCCCCCHHHHHHHHHCCCCCCCCCC
AGRRILVVGAGQRVIDDPDPPVGNGRAISLLFAREGATLTCVDISEPAVAETCRQAKDLG
CCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHCC
ATVFAEVADVERAETIAPLVERAARQMGGLDGLVMVVGISSALPIDKQDANTWDREYAVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCHHEEEE
VRSNMLFAQQAMRHMEPGSSIVLMSSLAALRNSSGNPAYESSKAAQVALARSIAMAGQKQ
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
GIRCNSLLPGLMDTPMGRAATARRPARVGGALPFGRQGTGWEVAYACLFLMSHESSYVNA
CCCHHHCCCCHHCCCCCCHHHCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEE
HALQVDGGLAAGVALTA
EEEEECCCEECCEEECC
>Mature Secondary Structure
MKTFHSWTPISLLGKLIPHGKRFHIWNYNGDNMTTTRPIHPEVQCFDEALGQTPPAGGRL
CCCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCEECCCCCCHHHHHHHHHCCCCCCCCCC
AGRRILVVGAGQRVIDDPDPPVGNGRAISLLFAREGATLTCVDISEPAVAETCRQAKDLG
CCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHCC
ATVFAEVADVERAETIAPLVERAARQMGGLDGLVMVVGISSALPIDKQDANTWDREYAVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCHHEEEE
VRSNMLFAQQAMRHMEPGSSIVLMSSLAALRNSSGNPAYESSKAAQVALARSIAMAGQKQ
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
GIRCNSLLPGLMDTPMGRAATARRPARVGGALPFGRQGTGWEVAYACLFLMSHESSYVNA
CCCHHHCCCCHHCCCCCCHHHCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEE
HALQVDGGLAAGVALTA
EEEEECCCEECCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]