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The map label for this gene is ychM [C]

Identifier: 94313557

GI number: 94313557

Start: 1265295

End: 1267031

Strand: Reverse

Name: ychM [C]

Synonym: Rmet_4635

Alternate gene names: 94313557

Gene position: 1267031-1265295 (Counterclockwise)

Preceding gene: 94313558

Following gene: 94313555

Centisome position: 49.11

GC content: 66.67

Gene sequence:

>1737_bases
ATGGGGCTACCATGCGTCAGATACGCACCCGCGGGAAAAACAACAAAGGGAATCGTGACCACGACCGATTCGACGCACCC
GACCGACAGCGCGCGCGACGGCAGCCGCCTGCGCGACCTGGTTGCCGGCTGTTCGATAGCCGGCCTGCTGCTACCCGAAG
CGGTGGCGTACGCCGGCATCGCCAATTTGCCACCGCAGGCCGGCCTGATCGGCCTGCTGGTGGGCCTGGTGGTCTACGGT
CTCGCAGGCACCAGCCGGTTCGCGGTGGTTTCGGCCACGTCGTCCTCCGCAGCGGTGCTGGCCGCCATCACGCTTTCCAT
GTCCGGCGCGGACCCCGCACAGCGGCTGTTACTGGCGGCGGGGCTGGTGATCCTGAGCGGCTTCTTCCTGATGCTGGCCG
GGCTGGCCAAGCTGGGCGGCATCACCGAATTCATTGCCAAGCCGGTGCTGCGCGGATTTACGTTCGGCCTGGCCATCACC
ATCATCCTCAAGCAACTGGCCAGCGTGGTGGGCGTGCACCCCGCGCACAACGATCTGCCGCGCTTCACCTACGAAATGCT
GGGGCAGCTCTCGGCCTGGAACGTGAATGCGCTCATCGTCGCGCTGGTTGCGCTGGCGTTGCTGTTCGGCATGTCGCGCT
GGAAGAACGTCCCCGGCCCGCTGGTGGTAATCGTGCTCGGCATTGCCGCCTCGCATGGGGTGGACCTGCATCACTTCGGG
ATCGGGCAGGTCGGCACGATCGATCTGGCGGATCTGTCGTTCTCGATTCCCGACCTGTCGCGCAGCCAGTGGCTCAGGCT
CGGCGAACTGGCCTTCGCGCTGGTGCTGATCCTCTATGCGGAATCCTACAGTTCGATCCGGAGTTTCGCGCTCAAGCACG
GCGACAGCACGTCGGCGGACCGCGACCTGCTCGCGCTCGGCTTCGCGAACCTCGGCTCCGGGCTGTTGCATGGTATGCCG
GTGGGCGCCGGTTACTCGGCCACTTCGGCCAACGAAGCGGCCGGGGCAACGTCCCGGCTGGCGGGATGGTGCGCGGCCGT
GGTCGTCGCCGTGATCGTCGCGCTGTTGCTGCCGCAGCTGGCGCTGACCCCGGAACCGGTGCTGGCCGCCATCGTGGCCT
ACGCAGTCAGCCATACGCTGCGACTGAGCGTGTTCCGGCCCTATTGGTCATGGCAGCGCGACCGCCTGCTGGTGGTGGCG
GCGTGTGTGGCGGTGTTGCTGCTTGGCGTGCTGGATGGCCTGCTGGCCGGCATCGTGGTAAGCCTGCTGCTCACGCTCCG
CAATTTTTCCGAACCTCGGGTCAGCCAGTTGGGCCGACTGGGCACGAGCCACAACTACGTGGATGTCTCCAAGCATCCCG
AAGCCACGATTCCTCCCGGCTTGCTGATCGCGCGGCCCGAAGCGCCGCTGTTCTTCGCCAATGTGGAACGCATTCTGCTG
CGCGTGCGGCACCTGGCCGAGGCGGAGCAGGGCGCCGTGCACACCGTGATCATCAGCCTGGAGGAAACGCCTGACCTGGA
TGGTTCGACGATCGAGGCCTTGCGTACGTTCGCCGCGGGGGTAGCCAGCCGTGGCCGCCGACTGTTGCTGGTCCGTCTGA
AACCGCCTGCGCTGGACGTATTGACGCGCTCGGCGGACGATACGCTGCCGCTCGGCGCCCTGCATGAACTCAGCGTGGAT
GAGGCGGTGCAGTCGCTGGCCCTGGAATCCATCGGCGCCGATGCGCCGGCAACATGA

Upstream 100 bases:

>100_bases
CCGATGCCGACCTGAAGGACCTGCTGGCCTATCTGCATCACATGGCCGGGCGAAAGGCGCCATGAGGATGGAAAAAAGAG
GGGCCTGACTTGCCGGGCGC

Downstream 100 bases:

>100_bases
ACGCGGTGACGATCGGACGATCAGGCCATGATGTGTCGTAGCTGAGCCCACCACCGCAGCAAGGTGTGCATGATCCGCTC
AAAATCCTGCGCGATGGGCT

Product: sulfate transporter

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 578; Mature: 577

Protein sequence:

>578_residues
MGLPCVRYAPAGKTTKGIVTTTDSTHPTDSARDGSRLRDLVAGCSIAGLLLPEAVAYAGIANLPPQAGLIGLLVGLVVYG
LAGTSRFAVVSATSSSAAVLAAITLSMSGADPAQRLLLAAGLVILSGFFLMLAGLAKLGGITEFIAKPVLRGFTFGLAIT
IILKQLASVVGVHPAHNDLPRFTYEMLGQLSAWNVNALIVALVALALLFGMSRWKNVPGPLVVIVLGIAASHGVDLHHFG
IGQVGTIDLADLSFSIPDLSRSQWLRLGELAFALVLILYAESYSSIRSFALKHGDSTSADRDLLALGFANLGSGLLHGMP
VGAGYSATSANEAAGATSRLAGWCAAVVVAVIVALLLPQLALTPEPVLAAIVAYAVSHTLRLSVFRPYWSWQRDRLLVVA
ACVAVLLLGVLDGLLAGIVVSLLLTLRNFSEPRVSQLGRLGTSHNYVDVSKHPEATIPPGLLIARPEAPLFFANVERILL
RVRHLAEAEQGAVHTVIISLEETPDLDGSTIEALRTFAAGVASRGRRLLLVRLKPPALDVLTRSADDTLPLGALHELSVD
EAVQSLALESIGADAPAT

Sequences:

>Translated_578_residues
MGLPCVRYAPAGKTTKGIVTTTDSTHPTDSARDGSRLRDLVAGCSIAGLLLPEAVAYAGIANLPPQAGLIGLLVGLVVYG
LAGTSRFAVVSATSSSAAVLAAITLSMSGADPAQRLLLAAGLVILSGFFLMLAGLAKLGGITEFIAKPVLRGFTFGLAIT
IILKQLASVVGVHPAHNDLPRFTYEMLGQLSAWNVNALIVALVALALLFGMSRWKNVPGPLVVIVLGIAASHGVDLHHFG
IGQVGTIDLADLSFSIPDLSRSQWLRLGELAFALVLILYAESYSSIRSFALKHGDSTSADRDLLALGFANLGSGLLHGMP
VGAGYSATSANEAAGATSRLAGWCAAVVVAVIVALLLPQLALTPEPVLAAIVAYAVSHTLRLSVFRPYWSWQRDRLLVVA
ACVAVLLLGVLDGLLAGIVVSLLLTLRNFSEPRVSQLGRLGTSHNYVDVSKHPEATIPPGLLIARPEAPLFFANVERILL
RVRHLAEAEQGAVHTVIISLEETPDLDGSTIEALRTFAAGVASRGRRLLLVRLKPPALDVLTRSADDTLPLGALHELSVD
EAVQSLALESIGADAPAT
>Mature_577_residues
GLPCVRYAPAGKTTKGIVTTTDSTHPTDSARDGSRLRDLVAGCSIAGLLLPEAVAYAGIANLPPQAGLIGLLVGLVVYGL
AGTSRFAVVSATSSSAAVLAAITLSMSGADPAQRLLLAAGLVILSGFFLMLAGLAKLGGITEFIAKPVLRGFTFGLAITI
ILKQLASVVGVHPAHNDLPRFTYEMLGQLSAWNVNALIVALVALALLFGMSRWKNVPGPLVVIVLGIAASHGVDLHHFGI
GQVGTIDLADLSFSIPDLSRSQWLRLGELAFALVLILYAESYSSIRSFALKHGDSTSADRDLLALGFANLGSGLLHGMPV
GAGYSATSANEAAGATSRLAGWCAAVVVAVIVALLLPQLALTPEPVLAAIVAYAVSHTLRLSVFRPYWSWQRDRLLVVAA
CVAVLLLGVLDGLLAGIVVSLLLTLRNFSEPRVSQLGRLGTSHNYVDVSKHPEATIPPGLLIARPEAPLFFANVERILLR
VRHLAEAEQGAVHTVIISLEETPDLDGSTIEALRTFAAGVASRGRRLLLVRLKPPALDVLTRSADDTLPLGALHELSVDE
AVQSLALESIGADAPAT

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI94721253, Length=462, Percent_Identity=28.7878787878788, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI94721255, Length=462, Percent_Identity=28.7878787878788, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI94721259, Length=462, Percent_Identity=28.7878787878788, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI94721257, Length=462, Percent_Identity=28.7878787878788, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI45827800, Length=509, Percent_Identity=26.1296660117878, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI39752683, Length=509, Percent_Identity=26.3261296660118, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI269784651, Length=504, Percent_Identity=25, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI47131207, Length=624, Percent_Identity=25.3205128205128, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI20336272, Length=624, Percent_Identity=25.3205128205128, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI4557535, Length=545, Percent_Identity=23.4862385321101, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI16418413, Length=561, Percent_Identity=23.7076648841355, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI217272867, Length=561, Percent_Identity=23.7076648841355, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI45827802, Length=458, Percent_Identity=25.9825327510917, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI4505697, Length=479, Percent_Identity=25.0521920668058, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI100913030, Length=619, Percent_Identity=23.2633279483037, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI262206105, Length=143, Percent_Identity=35.6643356643357, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI262206075, Length=143, Percent_Identity=35.6643356643357, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI262206069, Length=143, Percent_Identity=35.6643356643357, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI262206063, Length=143, Percent_Identity=35.6643356643357, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI45827804, Length=243, Percent_Identity=28.8065843621399, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI87081859, Length=547, Percent_Identity=26.508226691042, Blast_Score=86, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17551690, Length=504, Percent_Identity=25.3968253968254, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17566848, Length=472, Percent_Identity=25.4237288135593, Blast_Score=105, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI86564876, Length=590, Percent_Identity=21.0169491525424, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17562578, Length=521, Percent_Identity=25.7197696737044, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI86564196, Length=475, Percent_Identity=22.5263157894737, Blast_Score=98, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI193203292, Length=492, Percent_Identity=23.3739837398374, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI86565215, Length=423, Percent_Identity=24.5862884160757, Blast_Score=82, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6325260, Length=504, Percent_Identity=22.6190476190476, Blast_Score=110, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6323121, Length=450, Percent_Identity=22.6666666666667, Blast_Score=84, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6319771, Length=444, Percent_Identity=21.8468468468468, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI19922482, Length=556, Percent_Identity=22.1223021582734, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI85815873, Length=422, Percent_Identity=26.5402843601896, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21358633, Length=564, Percent_Identity=21.9858156028369, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24666186, Length=406, Percent_Identity=24.1379310344828, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24651449, Length=135, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24649801, Length=268, Percent_Identity=24.2537313432836, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24647160, Length=135, Percent_Identity=30.3703703703704, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21355087, Length=135, Percent_Identity=30.3703703703704, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21358229, Length=139, Percent_Identity=31.6546762589928, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 60342; Mature: 60211

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS50801 STAS ; PS00626 RCC1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLPCVRYAPAGKTTKGIVTTTDSTHPTDSARDGSRLRDLVAGCSIAGLLLPEAVAYAGI
CCCCCCEECCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
ANLPPQAGLIGLLVGLVVYGLAGTSRFAVVSATSSSAAVLAAITLSMSGADPAQRLLLAA
CCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHH
GLVILSGFFLMLAGLAKLGGITEFIAKPVLRGFTFGLAITIILKQLASVVGVHPAHNDLP
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
RFTYEMLGQLSAWNVNALIVALVALALLFGMSRWKNVPGPLVVIVLGIAASHGVDLHHFG
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEECC
IGQVGTIDLADLSFSIPDLSRSQWLRLGELAFALVLILYAESYSSIRSFALKHGDSTSAD
CCCCCEEEEECCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
RDLLALGFANLGSGLLHGMPVGAGYSATSANEAAGATSRLAGWCAAVVVAVIVALLLPQL
CHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALTPEPVLAAIVAYAVSHTLRLSVFRPYWSWQRDRLLVVAACVAVLLLGVLDGLLAGIVV
HCCCCHHHHHHHHHHHHHHHHHEEECCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SLLLTLRNFSEPRVSQLGRLGTSHNYVDVSKHPEATIPPGLLIARPEAPLFFANVERILL
HHHHHHHCCCCHHHHHHHCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCHHHHHHHHHH
RVRHLAEAEQGAVHTVIISLEETPDLDGSTIEALRTFAAGVASRGRRLLLVRLKPPALDV
HHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHH
LTRSADDTLPLGALHELSVDEAVQSLALESIGADAPAT
HHCCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GLPCVRYAPAGKTTKGIVTTTDSTHPTDSARDGSRLRDLVAGCSIAGLLLPEAVAYAGI
CCCCCEECCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
ANLPPQAGLIGLLVGLVVYGLAGTSRFAVVSATSSSAAVLAAITLSMSGADPAQRLLLAA
CCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHH
GLVILSGFFLMLAGLAKLGGITEFIAKPVLRGFTFGLAITIILKQLASVVGVHPAHNDLP
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
RFTYEMLGQLSAWNVNALIVALVALALLFGMSRWKNVPGPLVVIVLGIAASHGVDLHHFG
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEECC
IGQVGTIDLADLSFSIPDLSRSQWLRLGELAFALVLILYAESYSSIRSFALKHGDSTSAD
CCCCCEEEEECCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
RDLLALGFANLGSGLLHGMPVGAGYSATSANEAAGATSRLAGWCAAVVVAVIVALLLPQL
CHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALTPEPVLAAIVAYAVSHTLRLSVFRPYWSWQRDRLLVVAACVAVLLLGVLDGLLAGIVV
HCCCCHHHHHHHHHHHHHHHHHEEECCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SLLLTLRNFSEPRVSQLGRLGTSHNYVDVSKHPEATIPPGLLIARPEAPLFFANVERILL
HHHHHHHCCCCHHHHHHHCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCHHHHHHHHHH
RVRHLAEAEQGAVHTVIISLEETPDLDGSTIEALRTFAAGVASRGRRLLLVRLKPPALDV
HHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHH
LTRSADDTLPLGALHELSVDEAVQSLALESIGADAPAT
HHCCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]