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The map label for this gene is kipR [H]

Identifier: 94313534

GI number: 94313534

Start: 1238012

End: 1238869

Strand: Reverse

Name: kipR [H]

Synonym: Rmet_4612

Alternate gene names: 94313534

Gene position: 1238869-1238012 (Counterclockwise)

Preceding gene: 94313535

Following gene: 94313530

Centisome position: 48.02

GC content: 70.51

Gene sequence:

>858_bases
ATGGCGACGCGATCCTCCCCGGTCCAGCGCGCGCTTGCCGTGCTGCGGGCGCTCTCCGACCCCGAAGTGCGACGCATGAG
CGACGTAGCACGCGCGACGGGCCTGGACCCGGCCACCACGTCGCGCCTGCTCGACCTGCTGGTGCAGGAGGGCTTCGCCA
CCCGCGATGCCAGGCGTCACTATGGCATCGGCCCGGAGGTGTTCCAGCTTGCGGATGTCGGGCAGCGGCGTGTGGACCTG
CGCCAGCTTGCGCGACCCGCTCTGGAACGGCTCCAGGACGCGTTCGGCGATACGGCGGTGCTGACAGAAACCAGCCGTGG
AGAAGCCGTGTGTTCGGAGGTGATCACGGGCACGTATCCCGTTCACGCGAACTACGTGACGGTGGGCACTCGGCGCCCAC
TCGGGGTTGGCGCGGGCAGTCTGGCGGTGCTGGCTTGGCTGCCACCGGCCGAGCGCGCGCGACGCCTGCAGCAAACGGCC
CGCAAGCTGGCCAACTACCCGCAGCTCGATGCGGCATCCATTGCTGCCGAGGCGGACGCCGCGTGCGCGCGCGGCTACGT
GCTGTTTCTGGATTGGGTGGTGGAGGGGATGGGCGGTATCGCCGTGCCGATCCTCGACTACGACGGCTGGCCCATCGGCG
CGTTAAGCGTGGCGGCCCTGAGTACCCGCATCCGCAGCCGTGAGGCCGCCATGGCACGCCTGCTACGACAGGAAGCGCGC
CGCATCACCAGCGCATGGACGCGCGCCGTAGTGCCCGCAGGGGGCACTCAGCGTGCCGGCCCGCGAAGCAGGGGGGCCAG
CGCATCCGGAATCTCCACCTCGAAGCGCAGCACCGCGCTGGCCAAGGCCTTGCCGTAG

Upstream 100 bases:

>100_bases
TGGTCGCTGGCAAAGAAGATCAAGCGCGACACGCTGCAATCGTCGCACCATGGCTGAGCGCATGGGTGACGCCATGGCGG
CCCGCTAGGCCCATCGCATC

Downstream 100 bases:

>100_bases
TTGTCGATTGCCAGGCTGCGGGACACCCCACCACCGAGCGCGCCCTCGGCCACGAAGTTGAGGACCTGCAGGCCATCCAC
GTCAAACCTCGTGACCAGCC

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: Kip operon repressor protein [H]

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MATRSSPVQRALAVLRALSDPEVRRMSDVARATGLDPATTSRLLDLLVQEGFATRDARRHYGIGPEVFQLADVGQRRVDL
RQLARPALERLQDAFGDTAVLTETSRGEAVCSEVITGTYPVHANYVTVGTRRPLGVGAGSLAVLAWLPPAERARRLQQTA
RKLANYPQLDAASIAAEADAACARGYVLFLDWVVEGMGGIAVPILDYDGWPIGALSVAALSTRIRSREAAMARLLRQEAR
RITSAWTRAVVPAGGTQRAGPRSRGASASGISTSKRSTALAKALP

Sequences:

>Translated_285_residues
MATRSSPVQRALAVLRALSDPEVRRMSDVARATGLDPATTSRLLDLLVQEGFATRDARRHYGIGPEVFQLADVGQRRVDL
RQLARPALERLQDAFGDTAVLTETSRGEAVCSEVITGTYPVHANYVTVGTRRPLGVGAGSLAVLAWLPPAERARRLQQTA
RKLANYPQLDAASIAAEADAACARGYVLFLDWVVEGMGGIAVPILDYDGWPIGALSVAALSTRIRSREAAMARLLRQEAR
RITSAWTRAVVPAGGTQRAGPRSRGASASGISTSKRSTALAKALP
>Mature_284_residues
ATRSSPVQRALAVLRALSDPEVRRMSDVARATGLDPATTSRLLDLLVQEGFATRDARRHYGIGPEVFQLADVGQRRVDLR
QLARPALERLQDAFGDTAVLTETSRGEAVCSEVITGTYPVHANYVTVGTRRPLGVGAGSLAVLAWLPPAERARRLQQTAR
KLANYPQLDAASIAAEADAACARGYVLFLDWVVEGMGGIAVPILDYDGWPIGALSVAALSTRIRSREAAMARLLRQEARR
ITSAWTRAVVPAGGTQRAGPRSRGASASGISTSKRSTALAKALP

Specific function: Transcriptional repressor of the kip gene-containing operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786468, Length=240, Percent_Identity=26.25, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 30435; Mature: 30304

Theoretical pI: Translated: 11.14; Mature: 11.14

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED ; PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATRSSPVQRALAVLRALSDPEVRRMSDVARATGLDPATTSRLLDLLVQEGFATRDARRH
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHH
YGIGPEVFQLADVGQRRVDLRQLARPALERLQDAFGDTAVLTETSRGEAVCSEVITGTYP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCC
VHANYVTVGTRRPLGVGAGSLAVLAWLPPAERARRLQQTARKLANYPQLDAASIAAEADA
CCCCEEEECCCCCCCCCCCHHHHEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
ACARGYVLFLDWVVEGMGGIAVPILDYDGWPIGALSVAALSTRIRSREAAMARLLRQEAR
HHHCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RITSAWTRAVVPAGGTQRAGPRSRGASASGISTSKRSTALAKALP
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
ATRSSPVQRALAVLRALSDPEVRRMSDVARATGLDPATTSRLLDLLVQEGFATRDARRH
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHH
YGIGPEVFQLADVGQRRVDLRQLARPALERLQDAFGDTAVLTETSRGEAVCSEVITGTYP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCC
VHANYVTVGTRRPLGVGAGSLAVLAWLPPAERARRLQQTARKLANYPQLDAASIAAEADA
CCCCEEEECCCCCCCCCCCHHHHEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
ACARGYVLFLDWVVEGMGGIAVPILDYDGWPIGALSVAALSTRIRSREAAMARLLRQEAR
HHHCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RITSAWTRAVVPAGGTQRAGPRSRGASASGISTSKRSTALAKALP
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]