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The map label for this gene is dppA [H]

Identifier: 94313500

GI number: 94313500

Start: 1193231

End: 1194958

Strand: Direct

Name: dppA [H]

Synonym: Rmet_4578

Alternate gene names: 94313500

Gene position: 1193231-1194958 (Clockwise)

Preceding gene: 94313499

Following gene: 94313501

Centisome position: 46.25

GC content: 61.81

Gene sequence:

>1728_bases
ATGGTGCCCATTATCAAGGCGAATGTCGGCAGGACGAACTGGCCACTGATGGCGGCGAAAGCCGTGGCGGCTGCAGCGGC
GGCATTGGCCTGCGGCATCGCGGCCGCGCAGGCGGATGCGCCAAAGTACGGTGGCACGCTTGAGGTCGGATCGGTCTACC
CCACCATCTCGGCGTTGTCCTGGGATCTGGCGGACTGGAACTGGAAGCAGAACTACGACACCGGTCAGGTCTATGAACAA
CTGTTTGCCGCGGATCTCTCAAAGTCGCGCCGCAACGGCGGAAAGTACGCCTTCCAGGCCGATGCCTGGCTGCCGCCGGA
CGCGATCCGGGGCGAGCTGGCCGAAAGCTGGAAGTGGATCGACCCGCTGACGCTCGAGGTCAAACTGCGCAAAAACGTCC
GCTTCCCCGCGAAGCCGGGCGTAATGGAAGAACGGGAGCTGACGTCGGAAGATGTGCTGTTCAGCTACGGCCGCATGAAC
GCAAGCGCCAAGAAGATCCCCAGCTACTACGACTACCTGACCAAGGTCGAAGCACCGGACAAGTACACGGTCATCTTCCG
CTTCAAGGAATTCAATGCCGAGTGGGACTATCGCTTCGGCTGGGGCTACTACTCCGGCATCATGCCCAAGGAGGTAGCCA
CCGCCGGGGCCGCGAACTGGAAGAACGTCACCGGCACCGGCCCGTTCACGCTGAACCAGTTCACGCAGGGCAACTCCACC
ACCTATGTAAAGAACGCGCAGTACTGGGACACGGACAAAATCGGCGGCAAGGACTACAAGTTGCCGTTCGTCGACAAGAT
GGTGCTGCGCACCGTCAAGGATGAGGCCACGCGCAACACCATGCTGCGCACCGGCAAGCTCGATGTGCTGGAACTGGTGC
GCTGGACTGCCGTGGACGAGCTCAAGAAGAGCGCACCGCAACTCAAATGGTCGAAGTGGCTCTCGTACACCGGCCAGTAC
CTGGCGCTGCGCGTCGATACCAAGCCGTTCAACGACATCCGCGTGCGCCGCGCTCTCAATATGGCGGTCAACAAGCAGGA
GATCGTCAAGCAGTACTACGGCGGCAACGCGGAGCTTTTCGCCTACCCGCAGCATCCCGACTACGGTGGCTACTTCGAGC
CGCTGAGCACGATGCCGGATTCGGTGAAGGAGCTGTTCACCTACAACCCCGAGAAGGCGAAGAAGCTGCTGGCGGAGGCC
GGCTATCCGAAGGGCTTCAAGTTCAAGGTTCAGGTATGCGCCTGCAACCAGGACCACATGGAGATGCTGCCGCTGATCGG
CGCTTACCTGGAACAGGTCGGCGTGAAGATCGAGATCCAGCCGATGGAGTACGGCGCGTACCTGTCCGCGATGACCACGA
AGACCAATGCGCCTGGCTACATGATGGCGAATGGCCATACGAATCCGACCACCACGTTGCGCAAGAGCTTCGTGGCCGGA
CAGGTGTGGAACGCCTCGCAATGGAATGATCCGGCCTTCACGGCCCGCGTCGACCAGGCCTTCCAGATCCGCGACGAAGG
CAAGCGCCAGGAGGCGATCCGCGCCATGACCCGCGACATCGTCGCGCAAGCGCCGTACATCTGGCTGCCGACGCCCTACG
TATTCACCGCCTGGTGGCCGTGGGTCAAGAACTACGACGGCGAACTGCGCGCTGGCGCCGTGCGTAGCGGCCCGATCTAC
GCGCGCGCATGGATCGATCAGGAGATGAAGAAGAAGCTTGGCTTCTGA

Upstream 100 bases:

>100_bases
ACCCACGCCTACGCGGCGGCCGCTGAAACGCGCCCGCCAACACCGGCCGGCAATGTGGCCCGCCGAATCACGACTCTTCA
GACCCTGTAAGGAGCAAGAG

Downstream 100 bases:

>100_bases
TCCGCCGCAAACCCGCCCCTCCAACCACCTGAGCGTAACCATGACAGAGCCCATTCTGCAGGTGAGAGACCTGACCACGC
GCTTTCGTACCGACCGGGGC

Product: ABC-type dipeptide/oligopeptide/nickel transport system, substrate binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 575; Mature: 575

Protein sequence:

>575_residues
MVPIIKANVGRTNWPLMAAKAVAAAAAALACGIAAAQADAPKYGGTLEVGSVYPTISALSWDLADWNWKQNYDTGQVYEQ
LFAADLSKSRRNGGKYAFQADAWLPPDAIRGELAESWKWIDPLTLEVKLRKNVRFPAKPGVMEERELTSEDVLFSYGRMN
ASAKKIPSYYDYLTKVEAPDKYTVIFRFKEFNAEWDYRFGWGYYSGIMPKEVATAGAANWKNVTGTGPFTLNQFTQGNST
TYVKNAQYWDTDKIGGKDYKLPFVDKMVLRTVKDEATRNTMLRTGKLDVLELVRWTAVDELKKSAPQLKWSKWLSYTGQY
LALRVDTKPFNDIRVRRALNMAVNKQEIVKQYYGGNAELFAYPQHPDYGGYFEPLSTMPDSVKELFTYNPEKAKKLLAEA
GYPKGFKFKVQVCACNQDHMEMLPLIGAYLEQVGVKIEIQPMEYGAYLSAMTTKTNAPGYMMANGHTNPTTTLRKSFVAG
QVWNASQWNDPAFTARVDQAFQIRDEGKRQEAIRAMTRDIVAQAPYIWLPTPYVFTAWWPWVKNYDGELRAGAVRSGPIY
ARAWIDQEMKKKLGF

Sequences:

>Translated_575_residues
MVPIIKANVGRTNWPLMAAKAVAAAAAALACGIAAAQADAPKYGGTLEVGSVYPTISALSWDLADWNWKQNYDTGQVYEQ
LFAADLSKSRRNGGKYAFQADAWLPPDAIRGELAESWKWIDPLTLEVKLRKNVRFPAKPGVMEERELTSEDVLFSYGRMN
ASAKKIPSYYDYLTKVEAPDKYTVIFRFKEFNAEWDYRFGWGYYSGIMPKEVATAGAANWKNVTGTGPFTLNQFTQGNST
TYVKNAQYWDTDKIGGKDYKLPFVDKMVLRTVKDEATRNTMLRTGKLDVLELVRWTAVDELKKSAPQLKWSKWLSYTGQY
LALRVDTKPFNDIRVRRALNMAVNKQEIVKQYYGGNAELFAYPQHPDYGGYFEPLSTMPDSVKELFTYNPEKAKKLLAEA
GYPKGFKFKVQVCACNQDHMEMLPLIGAYLEQVGVKIEIQPMEYGAYLSAMTTKTNAPGYMMANGHTNPTTTLRKSFVAG
QVWNASQWNDPAFTARVDQAFQIRDEGKRQEAIRAMTRDIVAQAPYIWLPTPYVFTAWWPWVKNYDGELRAGAVRSGPIY
ARAWIDQEMKKKLGF
>Mature_575_residues
MVPIIKANVGRTNWPLMAAKAVAAAAAALACGIAAAQADAPKYGGTLEVGSVYPTISALSWDLADWNWKQNYDTGQVYEQ
LFAADLSKSRRNGGKYAFQADAWLPPDAIRGELAESWKWIDPLTLEVKLRKNVRFPAKPGVMEERELTSEDVLFSYGRMN
ASAKKIPSYYDYLTKVEAPDKYTVIFRFKEFNAEWDYRFGWGYYSGIMPKEVATAGAANWKNVTGTGPFTLNQFTQGNST
TYVKNAQYWDTDKIGGKDYKLPFVDKMVLRTVKDEATRNTMLRTGKLDVLELVRWTAVDELKKSAPQLKWSKWLSYTGQY
LALRVDTKPFNDIRVRRALNMAVNKQEIVKQYYGGNAELFAYPQHPDYGGYFEPLSTMPDSVKELFTYNPEKAKKLLAEA
GYPKGFKFKVQVCACNQDHMEMLPLIGAYLEQVGVKIEIQPMEYGAYLSAMTTKTNAPGYMMANGHTNPTTTLRKSFVAG
QVWNASQWNDPAFTARVDQAFQIRDEGKRQEAIRAMTRDIVAQAPYIWLPTPYVFTAWWPWVKNYDGELRAGAVRSGPIY
ARAWIDQEMKKKLGF

Specific function: Important role in heme acquisition or metabolism [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=461, Percent_Identity=27.9826464208243, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1787052, Length=340, Percent_Identity=27.3529411764706, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1787551, Length=553, Percent_Identity=23.3273056057866, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1789397, Length=330, Percent_Identity=23.3333333333333, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1787495, Length=346, Percent_Identity=22.2543352601156, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1787762, Length=261, Percent_Identity=24.904214559387, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 65160; Mature: 65160

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPIIKANVGRTNWPLMAAKAVAAAAAALACGIAAAQADAPKYGGTLEVGSVYPTISALS
CCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHEE
WDLADWNWKQNYDTGQVYEQLFAADLSKSRRNGGKYAFQADAWLPPDAIRGELAESWKWI
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCC
DPLTLEVKLRKNVRFPAKPGVMEERELTSEDVLFSYGRMNASAKKIPSYYDYLTKVEAPD
CCEEEEEEEECCCCCCCCCCCCCHHHCCCHHHHHHHCCCCCCHHHCCHHHHHHHHCCCCC
KYTVIFRFKEFNAEWDYRFGWGYYSGIMPKEVATAGAANWKNVTGTGPFTLNQFTQGNST
CEEEEEEEEECCCCCCEEECCHHHCCCCCHHHHHCCCCCCCCCCCCCCEEECCCCCCCCE
TYVKNAQYWDTDKIGGKDYKLPFVDKMVLRTVKDEATRNTMLRTGKLDVLELVRWTAVDE
EEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LKKSAPQLKWSKWLSYTGQYLALRVDTKPFNDIRVRRALNMAVNKQEIVKQYYGGNAELF
HHHHCCCCHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCEEEE
AYPQHPDYGGYFEPLSTMPDSVKELFTYNPEKAKKLLAEAGYPKGFKFKVQVCACNQDHM
EECCCCCCCCCCCCHHCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEEEECCCHHH
EMLPLIGAYLEQVGVKIEIQPMEYGAYLSAMTTKTNAPGYMMANGHTNPTTTLRKSFVAG
HHHHHHHHHHHHCCCEEEEEECCCCCEEEHEEECCCCCCEEEECCCCCCHHHHHHHHHHC
QVWNASQWNDPAFTARVDQAFQIRDEGKRQEAIRAMTRDIVAQAPYIWLPTPYVFTAWWP
CCCCCCCCCCCCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEECCCCEEEEECH
WVKNYDGELRAGAVRSGPIYARAWIDQEMKKKLGF
HHHCCCCCEEECCCCCCCEEEEHHHHHHHHHHCCC
>Mature Secondary Structure
MVPIIKANVGRTNWPLMAAKAVAAAAAALACGIAAAQADAPKYGGTLEVGSVYPTISALS
CCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHEE
WDLADWNWKQNYDTGQVYEQLFAADLSKSRRNGGKYAFQADAWLPPDAIRGELAESWKWI
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCC
DPLTLEVKLRKNVRFPAKPGVMEERELTSEDVLFSYGRMNASAKKIPSYYDYLTKVEAPD
CCEEEEEEEECCCCCCCCCCCCCHHHCCCHHHHHHHCCCCCCHHHCCHHHHHHHHCCCCC
KYTVIFRFKEFNAEWDYRFGWGYYSGIMPKEVATAGAANWKNVTGTGPFTLNQFTQGNST
CEEEEEEEEECCCCCCEEECCHHHCCCCCHHHHHCCCCCCCCCCCCCCEEECCCCCCCCE
TYVKNAQYWDTDKIGGKDYKLPFVDKMVLRTVKDEATRNTMLRTGKLDVLELVRWTAVDE
EEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LKKSAPQLKWSKWLSYTGQYLALRVDTKPFNDIRVRRALNMAVNKQEIVKQYYGGNAELF
HHHHCCCCHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCEEEE
AYPQHPDYGGYFEPLSTMPDSVKELFTYNPEKAKKLLAEAGYPKGFKFKVQVCACNQDHM
EECCCCCCCCCCCCHHCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEEEECCCHHH
EMLPLIGAYLEQVGVKIEIQPMEYGAYLSAMTTKTNAPGYMMANGHTNPTTTLRKSFVAG
HHHHHHHHHHHHCCCEEEEEECCCCCEEEHEEECCCCCCEEEECCCCCCHHHHHHHHHHC
QVWNASQWNDPAFTARVDQAFQIRDEGKRQEAIRAMTRDIVAQAPYIWLPTPYVFTAWWP
CCCCCCCCCCCCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEECCCCEEEEECH
WVKNYDGELRAGAVRSGPIYARAWIDQEMKKKLGF
HHHCCCCCEEECCCCCCCEEEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]