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The map label for this gene is yngJ [H]

Identifier: 94313496

GI number: 94313496

Start: 1188656

End: 1189840

Strand: Direct

Name: yngJ [H]

Synonym: Rmet_4574

Alternate gene names: 94313496

Gene position: 1188656-1189840 (Clockwise)

Preceding gene: 94313487

Following gene: 94313497

Centisome position: 46.07

GC content: 65.23

Gene sequence:

>1185_bases
GTGGACGGACTGGAGACATTTCGGCAGGAGGCGCATGCCTGGCTGGAAGCGAACTGCCCGGCGGAGATGCGCCAACCGGT
GCGCAACGAGGACGACATCTGCTGGGGCGGGCGCAAGTTCCGCTATCAGTCCGATGCGCAGCGCCTGTGGCTGCAACGCA
TGGCCGAAAAGGGCTGGACCGTTCCGGAGTGGCCAACCCAATATGGCGGCGGCGGGCTCAGTCCGGCGCAGGCCCGGGTG
CTGCGCGCCGAAATGGCCCGATTGAACTGCCGGACGCCGCTGCAGAGCTTCGGCATCTCGATGCTGGGCCCGGCGCTGCT
GAAGTACGGCACCGAGGCGCAAAAGCAGGGGCACCTGCCCAAGATCGCACGCGGAGAGATCCGCTGGTGCCAGGGCTACT
CGGAGCCCAATGCCGGCTCCGACCTGGCGGCGCTGCAAACGCGCGCTGAAGAGCGTGACGGCCACTTTATCGTCAACGGC
CAGAAGATCTGGACTTCGTACGCCGACAAGGCCGACTGGATCTTCTGCCTGGTGCGCACCGACTTCCAGGCGCAGAAGCA
CACGGGTATCAGTTTCCTGTTGTTCGACATGGAAACCCCCGGGGTCTCCACCCGGCCCATCGTGCTGATCTCAGGCAAAT
CTCCCTTCTGCGAGACCTTCTTCGACGATGTGAAGGTGCCGTGCCACCAGTTGGTCGGCGAGCCGAACCGTGGATGGGAA
ATCGCCAAGTATCTGCTGACGCACGAGCGCGAAATGATCAGCGCCATTGGCAGCCGTGGCTTCCGCGAGCCCATGGGTCG
CCACGCGGCGAAAGTCATCGGCGTGGATGCGCAACGCCGCCTCGACGATCCGATGCTGCGTGCCCAGATTGCCCAGTTCG
AGATTGACGAAGCCGCCTTTGCGGCCGCCGGCGAGCGGGCACGCGACCTGGCCAAGCAAGGCGAGGGAATGGCAGCGTTC
TCTTCCGTGCTGAAGTACTACGGCGCAGAACTGAACAAGCGACGCTATGAACTGTTGATGTCCGTCGGCGGCACTGACGC
CCTGGAGTGGGAAGGCGAACGCAGCCAGGACGGCGCCCTGGCGCGGAGCTGGCTGCGCACCAAGGCCAATTCGATCGAGG
GCGGGACCAGCGAGGTGCAGCTCAACATCGTCGCCAAGCGCCTGCTCGGCCTCCCGGGCGCCTGA

Upstream 100 bases:

>100_bases
AGAAAAATAAGACTGTGGCATGGAACAACCTTGATCCGATTTTCCGGCAGACCGATGCCCGCGTGGCACGGCTTCCCAGG
GACGCAACAAGGAGACAATT

Downstream 100 bases:

>100_bases
CGTACCGGCTCGCCCGTACCGCCACGCCTACCGCAGCCCAAAGACATCGAAGCCCTCGAAGCCCAAGGACCGTCAAAGCC
GCCATGCCCATCGTATTCGA

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MDGLETFRQEAHAWLEANCPAEMRQPVRNEDDICWGGRKFRYQSDAQRLWLQRMAEKGWTVPEWPTQYGGGGLSPAQARV
LRAEMARLNCRTPLQSFGISMLGPALLKYGTEAQKQGHLPKIARGEIRWCQGYSEPNAGSDLAALQTRAEERDGHFIVNG
QKIWTSYADKADWIFCLVRTDFQAQKHTGISFLLFDMETPGVSTRPIVLISGKSPFCETFFDDVKVPCHQLVGEPNRGWE
IAKYLLTHEREMISAIGSRGFREPMGRHAAKVIGVDAQRRLDDPMLRAQIAQFEIDEAAFAAAGERARDLAKQGEGMAAF
SSVLKYYGAELNKRRYELLMSVGGTDALEWEGERSQDGALARSWLRTKANSIEGGTSEVQLNIVAKRLLGLPGA

Sequences:

>Translated_394_residues
MDGLETFRQEAHAWLEANCPAEMRQPVRNEDDICWGGRKFRYQSDAQRLWLQRMAEKGWTVPEWPTQYGGGGLSPAQARV
LRAEMARLNCRTPLQSFGISMLGPALLKYGTEAQKQGHLPKIARGEIRWCQGYSEPNAGSDLAALQTRAEERDGHFIVNG
QKIWTSYADKADWIFCLVRTDFQAQKHTGISFLLFDMETPGVSTRPIVLISGKSPFCETFFDDVKVPCHQLVGEPNRGWE
IAKYLLTHEREMISAIGSRGFREPMGRHAAKVIGVDAQRRLDDPMLRAQIAQFEIDEAAFAAAGERARDLAKQGEGMAAF
SSVLKYYGAELNKRRYELLMSVGGTDALEWEGERSQDGALARSWLRTKANSIEGGTSEVQLNIVAKRLLGLPGA
>Mature_394_residues
MDGLETFRQEAHAWLEANCPAEMRQPVRNEDDICWGGRKFRYQSDAQRLWLQRMAEKGWTVPEWPTQYGGGGLSPAQARV
LRAEMARLNCRTPLQSFGISMLGPALLKYGTEAQKQGHLPKIARGEIRWCQGYSEPNAGSDLAALQTRAEERDGHFIVNG
QKIWTSYADKADWIFCLVRTDFQAQKHTGISFLLFDMETPGVSTRPIVLISGKSPFCETFFDDVKVPCHQLVGEPNRGWE
IAKYLLTHEREMISAIGSRGFREPMGRHAAKVIGVDAQRRLDDPMLRAQIAQFEIDEAAFAAAGERARDLAKQGEGMAAF
SSVLKYYGAELNKRRYELLMSVGGTDALEWEGERSQDGALARSWLRTKANSIEGGTSEVQLNIVAKRLLGLPGA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958414, Length=234, Percent_Identity=31.1965811965812, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI226958412, Length=216, Percent_Identity=31.9444444444444, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI4501859, Length=358, Percent_Identity=25.1396648044693, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI4501857, Length=329, Percent_Identity=24.0121580547112, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI4557233, Length=365, Percent_Identity=25.4794520547945, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI4557231, Length=209, Percent_Identity=28.2296650717703, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI187960098, Length=209, Percent_Identity=28.2296650717703, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI76496475, Length=214, Percent_Identity=29.9065420560748, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI4557235, Length=214, Percent_Identity=29.9065420560748, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI211971008, Length=145, Percent_Identity=34.4827586206897, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI48976061, Length=145, Percent_Identity=34.4827586206897, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI21361497, Length=209, Percent_Identity=27.7511961722488, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI7656849, Length=256, Percent_Identity=26.171875, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4503943, Length=139, Percent_Identity=30.9352517985612, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI7669494, Length=118, Percent_Identity=32.2033898305085, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87081958, Length=355, Percent_Identity=21.9718309859155, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786223, Length=351, Percent_Identity=20.5128205128205, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17551932, Length=347, Percent_Identity=25.3602305475504, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17505929, Length=349, Percent_Identity=26.3610315186246, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17508101, Length=409, Percent_Identity=24.9388753056235, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17538396, Length=214, Percent_Identity=28.0373831775701, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17534899, Length=248, Percent_Identity=28.6290322580645, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17570075, Length=360, Percent_Identity=25.2777777777778, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17569725, Length=207, Percent_Identity=28.9855072463768, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71985184, Length=226, Percent_Identity=32.7433628318584, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17506239, Length=368, Percent_Identity=26.0869565217391, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71985192, Length=226, Percent_Identity=32.7433628318584, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI32563615, Length=196, Percent_Identity=30.1020408163265, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71990804, Length=203, Percent_Identity=26.1083743842365, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17533517, Length=195, Percent_Identity=29.2307692307692, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71982178, Length=192, Percent_Identity=26.5625, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21356377, Length=396, Percent_Identity=27.5252525252525, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24666513, Length=359, Percent_Identity=23.9554317548747, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21355753, Length=217, Percent_Identity=29.0322580645161, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281363737, Length=205, Percent_Identity=27.8048780487805, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24646207, Length=303, Percent_Identity=26.0726072607261, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24660351, Length=361, Percent_Identity=24.3767313019391, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 44055; Mature: 44055

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGLETFRQEAHAWLEANCPAEMRQPVRNEDDICWGGRKFRYQSDAQRLWLQRMAEKGWT
CCHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCEEECCCEECCHHHHHHHHHHHHHHCCCC
VPEWPTQYGGGGLSPAQARVLRAEMARLNCRTPLQSFGISMLGPALLKYGTEAQKQGHLP
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHCCHHHHCCCCC
KIARGEIRWCQGYSEPNAGSDLAALQTRAEERDGHFIVNGQKIWTSYADKADWIFCLVRT
CHHCCCCCEECCCCCCCCCCHHHHHHHHHHCCCCCEEECCHHHHHHHCCCCCEEEEEEEC
DFQAQKHTGISFLLFDMETPGVSTRPIVLISGKSPFCETFFDDVKVPCHQLVGEPNRGWE
CCCHHHCCCCEEEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHCCCHHHHCCCCCCCHH
IAKYLLTHEREMISAIGSRGFREPMGRHAAKVIGVDAQRRLDDPMLRAQIAQFEIDEAAF
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHH
AAAGERARDLAKQGEGMAAFSSVLKYYGAELNKRRYELLMSVGGTDALEWEGERSQDGAL
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHH
ARSWLRTKANSIEGGTSEVQLNIVAKRLLGLPGA
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDGLETFRQEAHAWLEANCPAEMRQPVRNEDDICWGGRKFRYQSDAQRLWLQRMAEKGWT
CCHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCEEECCCEECCHHHHHHHHHHHHHHCCCC
VPEWPTQYGGGGLSPAQARVLRAEMARLNCRTPLQSFGISMLGPALLKYGTEAQKQGHLP
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHCCHHHHCCCCC
KIARGEIRWCQGYSEPNAGSDLAALQTRAEERDGHFIVNGQKIWTSYADKADWIFCLVRT
CHHCCCCCEECCCCCCCCCCHHHHHHHHHHCCCCCEEECCHHHHHHHCCCCCEEEEEEEC
DFQAQKHTGISFLLFDMETPGVSTRPIVLISGKSPFCETFFDDVKVPCHQLVGEPNRGWE
CCCHHHCCCCEEEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHCCCHHHHCCCCCCCHH
IAKYLLTHEREMISAIGSRGFREPMGRHAAKVIGVDAQRRLDDPMLRAQIAQFEIDEAAF
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHH
AAAGERARDLAKQGEGMAAFSSVLKYYGAELNKRRYELLMSVGGTDALEWEGERSQDGAL
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHH
ARSWLRTKANSIEGGTSEVQLNIVAKRLLGLPGA
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]