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The map label for this gene is codA [H]

Identifier: 94313490

GI number: 94313490

Start: 1181175

End: 1182455

Strand: Reverse

Name: codA [H]

Synonym: Rmet_4568

Alternate gene names: 94313490

Gene position: 1182455-1181175 (Counterclockwise)

Preceding gene: 94313491

Following gene: 94313489

Centisome position: 45.83

GC content: 65.89

Gene sequence:

>1281_bases
ATGTTCGACACCATCCTGCGCCACTGCAATATGCCTGACGGACGTACCGATATCGATATCGGCATTGCCAACGGGCGGAT
CGCGGCGGTGGAGCCACGGATCGCGGCAACGGCGGGCGAGGAGATCGACGCTGCTGGACAGCTTGTCTCGCCGCCGTTCG
TCGATGCGCACTTCCATATGGACTCCACGCTGTCATACGGCCTGCCGCGCGTGAACCAGTCCGGCACGCTGCTCGAGGGC
ATCGCGCTGTGGGGGGAGCTGAAGCCGCTGCTTACGCAGGATGCCATCGTCGAGCGCGCGCTGGCGTATTGCGACTGGGC
CGTCTCCAAAGGGCTGCTGGCGATCCGTTCCCACGTGGATGTGTGCGATCCGCGCCTGCTGGCCACGGAGGCGCTGCTGC
ACGTGCGTGAGCGCGTCAGGCCCTACCTGGATCTGCAACTCGTGGCATTTCCGCAGGACGGTCTGCTGCGCGCACCGGAT
GCGCTCAACAACCTTCGCCGCGCGCTGGACCTTGGCGTCGATGTGGTGGGCGGCATTCCGCATTTTGAGCGCACGATGGC
CGACGGCGCGGCGTCGGTGAAGATGCTCTGCGAGGAAGCCGCCGAGCGCGGGTTGCGCGTGGACATGCATTGCGACGAAA
GCGACGACCCGATGTCGCGCCATATCGAGACGCTGGCGAGCGAATCGGTACGGCTGGGTTTGCAGGGACGCGTCACGGGT
TCGCATCTGACGTCGATGCATTCGATGGACAATTACTACGTCTCCAAGCTGCTGCCGCTGATGCGAGAGGCCGGCGTATC
GGCCATCGCCAATCCGCTGATCAACATCACGCTGCAGGGGCGGCACGATACCTATCCGAAGCGGCGCGGCATGACGCGCG
TGCCCGAGATGCTTGCCGCCGGCATTCCTGTGGCCTTCGGTCACGACTGTGTGATGGACCCCTGGTACAGCCTTGGCTCG
GGCGACATGCTAGAGGTGGCCCACATGGGTCTGCACGTCGCGCAGATGACGGGGCAGGACGCCATGCGCGCGTGTTTCAC
CGCTGTGACAGAAACGCCGGCACGTATCCTGGGTCTCGAAGGCTATGGGATCTCGCCGGGCCGCCGCGCGGATCTGGTGC
TGCTGCAGGCGCGGGACCCGGTGGAGGCGCTCCGCCTGCGCGCAACGCGGCTGCTGGTAATGCGGGCAGGGAATGTCATC
GCCCGCACGGCGCCGGCCACCGCAATGCTGGCGCTCGCGGGTCGACCGGCTCAAGTCGACTTCCAGTTACACCGGGCATG
A

Upstream 100 bases:

>100_bases
AAGCCTCGCTGGCCTGAGCCAGCATCTAGCATGGCAGTTGCCATGCAGTCTTCGTCTACCATTGCCACGTCACCGCCACC
GGGATCACAAGGGACGCCTC

Downstream 100 bases:

>100_bases
CGATGTGGAGCGTTTTTTGAAGAATCGATGAATTTTGTGTTGACAGAGATCGGCTTGCTCAGCATAATCTCTTTCTTCGC
ATCGCAGCAGCAATGCAGCG

Product: cytosine deaminase

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MFDTILRHCNMPDGRTDIDIGIANGRIAAVEPRIAATAGEEIDAAGQLVSPPFVDAHFHMDSTLSYGLPRVNQSGTLLEG
IALWGELKPLLTQDAIVERALAYCDWAVSKGLLAIRSHVDVCDPRLLATEALLHVRERVRPYLDLQLVAFPQDGLLRAPD
ALNNLRRALDLGVDVVGGIPHFERTMADGAASVKMLCEEAAERGLRVDMHCDESDDPMSRHIETLASESVRLGLQGRVTG
SHLTSMHSMDNYYVSKLLPLMREAGVSAIANPLINITLQGRHDTYPKRRGMTRVPEMLAAGIPVAFGHDCVMDPWYSLGS
GDMLEVAHMGLHVAQMTGQDAMRACFTAVTETPARILGLEGYGISPGRRADLVLLQARDPVEALRLRATRLLVMRAGNVI
ARTAPATAMLALAGRPAQVDFQLHRA

Sequences:

>Translated_426_residues
MFDTILRHCNMPDGRTDIDIGIANGRIAAVEPRIAATAGEEIDAAGQLVSPPFVDAHFHMDSTLSYGLPRVNQSGTLLEG
IALWGELKPLLTQDAIVERALAYCDWAVSKGLLAIRSHVDVCDPRLLATEALLHVRERVRPYLDLQLVAFPQDGLLRAPD
ALNNLRRALDLGVDVVGGIPHFERTMADGAASVKMLCEEAAERGLRVDMHCDESDDPMSRHIETLASESVRLGLQGRVTG
SHLTSMHSMDNYYVSKLLPLMREAGVSAIANPLINITLQGRHDTYPKRRGMTRVPEMLAAGIPVAFGHDCVMDPWYSLGS
GDMLEVAHMGLHVAQMTGQDAMRACFTAVTETPARILGLEGYGISPGRRADLVLLQARDPVEALRLRATRLLVMRAGNVI
ARTAPATAMLALAGRPAQVDFQLHRA
>Mature_426_residues
MFDTILRHCNMPDGRTDIDIGIANGRIAAVEPRIAATAGEEIDAAGQLVSPPFVDAHFHMDSTLSYGLPRVNQSGTLLEG
IALWGELKPLLTQDAIVERALAYCDWAVSKGLLAIRSHVDVCDPRLLATEALLHVRERVRPYLDLQLVAFPQDGLLRAPD
ALNNLRRALDLGVDVVGGIPHFERTMADGAASVKMLCEEAAERGLRVDMHCDESDDPMSRHIETLASESVRLGLQGRVTG
SHLTSMHSMDNYYVSKLLPLMREAGVSAIANPLINITLQGRHDTYPKRRGMTRVPEMLAAGIPVAFGHDCVMDPWYSLGS
GDMLEVAHMGLHVAQMTGQDAMRACFTAVTETPARILGLEGYGISPGRRADLVLLQARDPVEALRLRATRLLVMRAGNVI
ARTAPATAMLALAGRPAQVDFQLHRA

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=405, Percent_Identity=45.1851851851852, Blast_Score=364, Evalue=1e-102,
Organism=Escherichia coli, GI1786517, Length=404, Percent_Identity=27.970297029703, Blast_Score=78, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 46348; Mature: 46348

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS01137 TATD_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDTILRHCNMPDGRTDIDIGIANGRIAAVEPRIAATAGEEIDAAGQLVSPPFVDAHFHM
CHHHHHHHCCCCCCCCEEEEEECCCEEEEECCCHHHCCCCCHHCCCCCCCCCCEEEEECC
DSTLSYGLPRVNQSGTLLEGIALWGELKPLLTQDAIVERALAYCDWAVSKGLLAIRSHVD
CCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCC
VCDPRLLATEALLHVRERVRPYLDLQLVAFPQDGLLRAPDALNNLRRALDLGVDVVGGIP
CCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCHHCCCCC
HFERTMADGAASVKMLCEEAAERGLRVDMHCDESDDPMSRHIETLASESVRLGLQGRVTG
HHHHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHEECEECCCCH
SHLTSMHSMDNYYVSKLLPLMREAGVSAIANPLINITLQGRHDTYPKRRGMTRVPEMLAA
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCEEEEEECCCCCCCHHHCCCHHHHHHHHC
GIPVAFGHDCVMDPWYSLGSGDMLEVAHMGLHVAQMTGQDAMRACFTAVTETPARILGLE
CCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHEEECC
GYGISPGRRADLVLLQARDPVEALRLRATRLLVMRAGNVIARTAPATAMLALAGRPAQVD
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHHEEHCCCCEEEECCCHHHHHHHCCCCCEEC
FQLHRA
EEEECC
>Mature Secondary Structure
MFDTILRHCNMPDGRTDIDIGIANGRIAAVEPRIAATAGEEIDAAGQLVSPPFVDAHFHM
CHHHHHHHCCCCCCCCEEEEEECCCEEEEECCCHHHCCCCCHHCCCCCCCCCCEEEEECC
DSTLSYGLPRVNQSGTLLEGIALWGELKPLLTQDAIVERALAYCDWAVSKGLLAIRSHVD
CCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCC
VCDPRLLATEALLHVRERVRPYLDLQLVAFPQDGLLRAPDALNNLRRALDLGVDVVGGIP
CCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCHHCCCCC
HFERTMADGAASVKMLCEEAAERGLRVDMHCDESDDPMSRHIETLASESVRLGLQGRVTG
HHHHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHEECEECCCCH
SHLTSMHSMDNYYVSKLLPLMREAGVSAIANPLINITLQGRHDTYPKRRGMTRVPEMLAA
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCEEEEEECCCCCCCHHHCCCHHHHHHHHC
GIPVAFGHDCVMDPWYSLGSGDMLEVAHMGLHVAQMTGQDAMRACFTAVTETPARILGLE
CCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHEEECC
GYGISPGRRADLVLLQARDPVEALRLRATRLLVMRAGNVIARTAPATAMLALAGRPAQVD
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHHEEHCCCCEEEECCCHHHHHHHCCCCCEEC
FQLHRA
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]