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The map label for this gene is sumF1 [H]

Identifier: 94313454

GI number: 94313454

Start: 1135785

End: 1137011

Strand: Reverse

Name: sumF1 [H]

Synonym: Rmet_4529

Alternate gene names: 94313454

Gene position: 1137011-1135785 (Counterclockwise)

Preceding gene: 94313455

Following gene: 94313453

Centisome position: 44.07

GC content: 68.46

Gene sequence:

>1227_bases
ATGGCACGTAAACAGCAGGAAAGAGCGGCGGCCGCGAGCGCGGCGCCGTCATCGTGGCGGCGGCGCATGTGGCTGGGCAC
ATTGGTCGTAGGGATGGCCGGGGCGGGCGCAGCCGGCACGGTCTGGTATAGCCGGCACAATGGGCAGGGCGTGGACCCCG
CGTCGATTCGCGCGGGCGACGGCGTCAGCGGCCCGGCCGGCATGGTGCATGTCCCGGGCGGCGAATTCCTGATGGGTAGT
GACCACAAGATGTCCCAGGCCAACGAGCGCCCGGCACACAAGGTACAGGTCAAGGCCTTTTGGATGGATCAGCACCACGT
CACCAATGCCGACTTCCGCAAGTTCGTCGAGGCCACGGGCTACCTGACCACGGCGGAGCGCAAGCCGGACTGGGAGACGC
TGAGGGTTCAGCTTCCGGCCGGCACGCCACGCCCGCCTGACAGTGCGATGGTCGCGGGCGGGATGGTGTTCGTCGGCACC
AACAGCCCGGTGCCGCTGCGCGAATACTGGCGCTGGTGGCGCTTCGTACCTGGCGCGGACTGGCGTCACCCGACCGGCCC
GGGCAGTTCCATCGAAGGCAAGGACAATCATCCCGTCGTGCAGGTCTCGTATGAAGACGCGCAGGCGTACGCCAAGTGGG
CCGGCAAGCGTCTGCCCACCGAGGCCGAGTGGGAGTTTGCCGCCCGTGGCGGCCTGGAGCAGGCCACCTACGCCTGGGGT
GACAAGTTCGCGCCGGATGGCCGGCAGATGGCGAATGTCTGGCAGGGCCAGCAGGTGCAGCCGTTCCCGGTGGTCAGCGC
CAAGGCGGGCGGCGCGGCTGGCACCAGTGCTGTCGGCACGTTCCCGGGCAATGGCTATGGGCTCTATGACATGACCGGCA
ACGCCTGGCAGTGGGTGGCCGACTGGTATCGCGCGGACCAGTTCCGCCGCGAAGCCACGGTGGCGGCAGTGCTGCAGAAT
CCGACCGGCCCGGCCGATTCGTGGGACCCGACCGAACCTGGCGTGCCGGTGTCGGCGCCCAAGCGGGTCACGCGCGGTGG
CTCGTTCCTCTGCAACGAGGACTTCTGCCTCAGCTACCGCCCGAGTGCCCGGCGCGGTACCGACCCGTACACCAGCATGT
CGCACCTAGGCTTCCGGCTCGTGATGGATGACGCCCGTTGGGCAGAAGTTCGCAAGCAGCCAGCCGTGGCAATGGCCGCG
GGCGGGCAGCAGAACGTGCAGAAATAA

Upstream 100 bases:

>100_bases
AAAAAATCATTCAGATCAGTCAATAAAATATTGCATTCCTTCGCCGAGCCAGGATGCTCATACTGCCCGAGTTCAGGATT
GCACCGGGCAAGGAACACTG

Downstream 100 bases:

>100_bases
CGCATCGAAGCGGCAAGCCGCAAAGCAGACATACAAGAGACGCACTGAACCGGAGAGAACCTGATGGAACACGCCCGCGC
ACCGTGGTTGCGACGCTGGA

Product: C-alpha-formyglycine- generating protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MARKQQERAAAASAAPSSWRRRMWLGTLVVGMAGAGAAGTVWYSRHNGQGVDPASIRAGDGVSGPAGMVHVPGGEFLMGS
DHKMSQANERPAHKVQVKAFWMDQHHVTNADFRKFVEATGYLTTAERKPDWETLRVQLPAGTPRPPDSAMVAGGMVFVGT
NSPVPLREYWRWWRFVPGADWRHPTGPGSSIEGKDNHPVVQVSYEDAQAYAKWAGKRLPTEAEWEFAARGGLEQATYAWG
DKFAPDGRQMANVWQGQQVQPFPVVSAKAGGAAGTSAVGTFPGNGYGLYDMTGNAWQWVADWYRADQFRREATVAAVLQN
PTGPADSWDPTEPGVPVSAPKRVTRGGSFLCNEDFCLSYRPSARRGTDPYTSMSHLGFRLVMDDARWAEVRKQPAVAMAA
GGQQNVQK

Sequences:

>Translated_408_residues
MARKQQERAAAASAAPSSWRRRMWLGTLVVGMAGAGAAGTVWYSRHNGQGVDPASIRAGDGVSGPAGMVHVPGGEFLMGS
DHKMSQANERPAHKVQVKAFWMDQHHVTNADFRKFVEATGYLTTAERKPDWETLRVQLPAGTPRPPDSAMVAGGMVFVGT
NSPVPLREYWRWWRFVPGADWRHPTGPGSSIEGKDNHPVVQVSYEDAQAYAKWAGKRLPTEAEWEFAARGGLEQATYAWG
DKFAPDGRQMANVWQGQQVQPFPVVSAKAGGAAGTSAVGTFPGNGYGLYDMTGNAWQWVADWYRADQFRREATVAAVLQN
PTGPADSWDPTEPGVPVSAPKRVTRGGSFLCNEDFCLSYRPSARRGTDPYTSMSHLGFRLVMDDARWAEVRKQPAVAMAA
GGQQNVQK
>Mature_407_residues
ARKQQERAAAASAAPSSWRRRMWLGTLVVGMAGAGAAGTVWYSRHNGQGVDPASIRAGDGVSGPAGMVHVPGGEFLMGSD
HKMSQANERPAHKVQVKAFWMDQHHVTNADFRKFVEATGYLTTAERKPDWETLRVQLPAGTPRPPDSAMVAGGMVFVGTN
SPVPLREYWRWWRFVPGADWRHPTGPGSSIEGKDNHPVVQVSYEDAQAYAKWAGKRLPTEAEWEFAARGGLEQATYAWGD
KFAPDGRQMANVWQGQQVQPFPVVSAKAGGAAGTSAVGTFPGNGYGLYDMTGNAWQWVADWYRADQFRREATVAAVLQNP
TGPADSWDPTEPGVPVSAPKRVTRGGSFLCNEDFCLSYRPSARRGTDPYTSMSHLGFRLVMDDARWAEVRKQPAVAMAAG
GQQNVQK

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI38202250, Length=317, Percent_Identity=41.0094637223975, Blast_Score=239, Evalue=2e-63,
Organism=Homo sapiens, GI257470975, Length=317, Percent_Identity=39.4321766561514, Blast_Score=230, Evalue=1e-60,
Organism=Homo sapiens, GI257470977, Length=317, Percent_Identity=37.8548895899054, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI194248088, Length=341, Percent_Identity=34.6041055718475, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI194248087, Length=334, Percent_Identity=34.1317365269461, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI194248090, Length=233, Percent_Identity=39.0557939914163, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI226437577, Length=218, Percent_Identity=38.9908256880734, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI20130397, Length=316, Percent_Identity=35.7594936708861, Blast_Score=186, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 44491; Mature: 44360

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARKQQERAAAASAAPSSWRRRMWLGTLVVGMAGAGAAGTVWYSRHNGQGVDPASIRAGD
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCEECCC
GVSGPAGMVHVPGGEFLMGSDHKMSQANERPAHKVQVKAFWMDQHHVTNADFRKFVEATG
CCCCCCCEEECCCCCEEECCCCCHHHCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHC
YLTTAERKPDWETLRVQLPAGTPRPPDSAMVAGGMVFVGTNSPVPLREYWRWWRFVPGAD
CEEECCCCCCCEEEEEECCCCCCCCCCCCEEECCEEEEECCCCCCHHHHHHHHHCCCCCC
WRHPTGPGSSIEGKDNHPVVQVSYEDAQAYAKWAGKRLPTEAEWEFAARGGLEQATYAWG
CCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCHHHHHCC
DKFAPDGRQMANVWQGQQVQPFPVVSAKAGGAAGTSAVGTFPGNGYGLYDMTGNAWQWVA
CCCCCCHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCEECCCCCCEEEEECCCCHHHHHH
DWYRADQFRREATVAAVLQNPTGPADSWDPTEPGVPVSAPKRVTRGGSFLCNEDFCLSYR
HHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCEEECCCCEEEEC
PSARRGTDPYTSMSHLGFRLVMDDARWAEVRKQPAVAMAAGGQQNVQK
CCCCCCCCCCCHHHHCCEEEEECCCHHHHHHCCCCEEEECCCHHCCCC
>Mature Secondary Structure 
ARKQQERAAAASAAPSSWRRRMWLGTLVVGMAGAGAAGTVWYSRHNGQGVDPASIRAGD
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCEECCC
GVSGPAGMVHVPGGEFLMGSDHKMSQANERPAHKVQVKAFWMDQHHVTNADFRKFVEATG
CCCCCCCEEECCCCCEEECCCCCHHHCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHC
YLTTAERKPDWETLRVQLPAGTPRPPDSAMVAGGMVFVGTNSPVPLREYWRWWRFVPGAD
CEEECCCCCCCEEEEEECCCCCCCCCCCCEEECCEEEEECCCCCCHHHHHHHHHCCCCCC
WRHPTGPGSSIEGKDNHPVVQVSYEDAQAYAKWAGKRLPTEAEWEFAARGGLEQATYAWG
CCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCHHHHHCC
DKFAPDGRQMANVWQGQQVQPFPVVSAKAGGAAGTSAVGTFPGNGYGLYDMTGNAWQWVA
CCCCCCHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCEECCCCCCEEEEECCCCHHHHHH
DWYRADQFRREATVAAVLQNPTGPADSWDPTEPGVPVSAPKRVTRGGSFLCNEDFCLSYR
HHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCEEECCCCEEEEC
PSARRGTDPYTSMSHLGFRLVMDDARWAEVRKQPAVAMAAGGQQNVQK
CCCCCCCCCCCHHHHCCEEEEECCCHHHHHHCCCCEEEECCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]