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The map label for this gene is paiB [H]

Identifier: 94313449

GI number: 94313449

Start: 1129002

End: 1129652

Strand: Reverse

Name: paiB [H]

Synonym: Rmet_4524

Alternate gene names: 94313449

Gene position: 1129652-1129002 (Counterclockwise)

Preceding gene: 94313450

Following gene: 94313447

Centisome position: 43.78

GC content: 62.52

Gene sequence:

>651_bases
ATGTACGTCCCTGCCCATTTCGAAGAATCGCGCCCTGAGGCTCTCCATGCGTTGATGACCGCGTATCCATTTGGCACGCT
GGTCACGCATGGCAGGAACGGTCTGGATGCGAATCACATTCCCTTCCATCTCGATCCCTCGCAAGGGCCGAATGGGATGC
TGAAGGCTCACGTTGCCCGCGCCAACCCGGTCTGGCAGGACGTGGCGGACGGTGATGAGGTACTGGTGATCTTCCGCGCC
GCTGATGCGTATATCTCGCCGAACTGGTATCCGAGCAAGCACGAGGCCCACAAGCAGGTGCCCACGTGGAACTACATGGT
CGTGCACGCGCACGGTCGCATCACGATTCGCGACGATGAACGCTTCGTGCGCGGCGTCGTGGCCCATCTGACGCGCACGC
ACGAGGCCACGCAACCGAGGCCGTGGAAGATGTCCGACGCCCCGTCGGATTTCGTCGACACGATGCTCAAGGCGATCGTC
GGTATCGAGATCGAGATCACGCGACTGGAAGGCAAGTTGAAGCTGAGTCAGAACAAGGAAGTGCGCGACATCCGTGGCGC
GGGCACGGCGCTGGCCGAGCAGGGCAGCACAACGCTCGGCGAAGCGATGCTGGCCCGCGCAGATGCCAAGGAGCGGGGCG
AGACCCAGTAA

Upstream 100 bases:

>100_bases
AGCGTGTGGGCGATAACCGCAAACTGCGGCTACACTCGGCTCCAGTTTCCGATGACAATGCCTGCATTCCGAACCCTACA
CCCCCACGCCCAGCACTCTC

Downstream 100 bases:

>100_bases
TTCCCGGGCCTTCCACCCTTTGCCTTCCGCCTCTCAGCGTCCCGTCGCGTACCGGGGCGCGGGAGTGTTGGTCGATAGCA
GGCCCGCCATCGCCTGGCGC

Product: Negative transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MYVPAHFEESRPEALHALMTAYPFGTLVTHGRNGLDANHIPFHLDPSQGPNGMLKAHVARANPVWQDVADGDEVLVIFRA
ADAYISPNWYPSKHEAHKQVPTWNYMVVHAHGRITIRDDERFVRGVVAHLTRTHEATQPRPWKMSDAPSDFVDTMLKAIV
GIEIEITRLEGKLKLSQNKEVRDIRGAGTALAEQGSTTLGEAMLARADAKERGETQ

Sequences:

>Translated_216_residues
MYVPAHFEESRPEALHALMTAYPFGTLVTHGRNGLDANHIPFHLDPSQGPNGMLKAHVARANPVWQDVADGDEVLVIFRA
ADAYISPNWYPSKHEAHKQVPTWNYMVVHAHGRITIRDDERFVRGVVAHLTRTHEATQPRPWKMSDAPSDFVDTMLKAIV
GIEIEITRLEGKLKLSQNKEVRDIRGAGTALAEQGSTTLGEAMLARADAKERGETQ
>Mature_216_residues
MYVPAHFEESRPEALHALMTAYPFGTLVTHGRNGLDANHIPFHLDPSQGPNGMLKAHVARANPVWQDVADGDEVLVIFRA
ADAYISPNWYPSKHEAHKQVPTWNYMVVHAHGRITIRDDERFVRGVVAHLTRTHEATQPRPWKMSDAPSDFVDTMLKAIV
GIEIEITRLEGKLKLSQNKEVRDIRGAGTALAEQGSTTLGEAMLARADAKERGETQ

Specific function: Involved in the reduction of extracellular and cell- associated protease levels, as well as in the reduced levels of alpha-amylase, levansucrase, alkaline phosphatase and sporulation inhibition, when present in high copy number [H]

COG id: COG2808

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the paiB family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322780, Length=159, Percent_Identity=33.9622641509434, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007396
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF04299 FMN_bind_2 [H]

EC number: NA

Molecular weight: Translated: 24073; Mature: 24073

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVPAHFEESRPEALHALMTAYPFGTLVTHGRNGLDANHIPFHLDPSQGPNGMLKAHVAR
CCCCCCCCCCCHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCEEECCCCCCCCCEEEEEEC
ANPVWQDVADGDEVLVIFRAADAYISPNWYPSKHEAHKQVPTWNYMVVHAHGRITIRDDE
CCCCHHHHCCCCEEEEEEEECCCEECCCCCCCHHHHHHCCCCCEEEEEEECCEEEEECCH
RFVRGVVAHLTRTHEATQPRPWKMSDAPSDFVDTMLKAIVGIEIEITRLEGKLKLSQNKE
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEEECCEEEECCCCC
VRDIRGAGTALAEQGSTTLGEAMLARADAKERGETQ
HHHHHCCCHHHHHCCCCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MYVPAHFEESRPEALHALMTAYPFGTLVTHGRNGLDANHIPFHLDPSQGPNGMLKAHVAR
CCCCCCCCCCCHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCEEECCCCCCCCCEEEEEEC
ANPVWQDVADGDEVLVIFRAADAYISPNWYPSKHEAHKQVPTWNYMVVHAHGRITIRDDE
CCCCHHHHCCCCEEEEEEEECCCEECCCCCCCHHHHHHCCCCCEEEEEEECCEEEEECCH
RFVRGVVAHLTRTHEATQPRPWKMSDAPSDFVDTMLKAIVGIEIEITRLEGKLKLSQNKE
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEEECCEEEECCCCC
VRDIRGAGTALAEQGSTTLGEAMLARADAKERGETQ
HHHHHCCCHHHHHCCCCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2108124; 9384377 [H]