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The map label for this gene is 94313338

Identifier: 94313338

GI number: 94313338

Start: 1008866

End: 1010035

Strand: Reverse

Name: 94313338

Synonym: Rmet_4413

Alternate gene names: NA

Gene position: 1010035-1008866 (Counterclockwise)

Preceding gene: 94313339

Following gene: 94313337

Centisome position: 39.15

GC content: 66.75

Gene sequence:

>1170_bases
ATGAGCATCAAGGGCAAGGCCTATATCGTCGGGGCCTACGAGCACCCGACGCGCAAGGCGCCGGACAAATCCGTCGCGCA
GCTTCACGCCGAATGCGCCAGAGGGGCACTGGAAGACGCCGGACTCTCCCTGTCCGACGTGGACGGCTACTTCTGCGCGG
GCGACGCACCGGGTCTCGGCGCGACCAACATGATCGACTACCTCGGGCTGCGCGTGCGGCATGTGGATTCGACCGACACG
GGCGGGTCCGCCTATCTGGTCCACGTATCGCACGCCGCGCAGGCGATTGCCGCCGGCAAATGCAACGTCGCGCTGATCAC
GCTGGCGGGCCGCCCACGCTCCGAAGGCTCCAGCGGCACGCAGGCACGCAACTGGGGCGCCAACCTGCCCGACGCGCCAT
TCGAGGCGCCGTTCCACCCGGTCACCGTGAACCTGTACGCGATGGTCGCCATGCGCCATATGCACGAGTACGGCACCACG
CCGGAACAGCTCGCGTGGATCAAGGTGGCCGCGTCCCATCACGCGCAGCACAACCCCCACGCGATGCTGCGCGACGTGGT
CACAGTGGAAGACGTACTGAACTCTCCGCTGATCTCCGACCCCTTGCGCAAGCTTGATTGCTGCGTGGTGTCCGACGGTG
GTGGCGCCCTGATCGTGGCATGCCCGGAGATCGCCGCGAAGCTGAAACGCCCCAAGGTACGCATCCTGGGCGCCGGCGAA
CACGTGAAGGGTCAGCTTGGCGGTCAGGTGGACCTGAGCTGGTCCGCCGCCCGCGTATCGGGTGCGGCAGCGTTCGCCGA
AGCAGGCATCACGCCCGCAGACATCAAGTACGCGTCCATCTACGACAGCTTCACCATCACTGTGCTGATGCAACTCGAAG
ACCTGGGCTTCTGCAAGAAAGGCGAAGGCGGCCGCTTCGTGGCCGACGGCAACCTGATTTCGGGCGTGGGCCGGCTGCCG
TTCAACACCGACGGCGGCGGGCTCTGCAACAACCATCCGGCCAATCGCGGCGGCATCACCAAGGTCATCGAGGCCGTGCG
CCAGTTGCGTGGCGAGGCCCATCCCGCTGTGCAGGTGAAGCACTGCGACCTGGCGCTGGCCCAGGGCACCGGCGGCTACC
TCGGCAGCCGCCATGGCAGCGCCACGCTGATTCTCGAACGGGAGCAATGA

Upstream 100 bases:

>100_bases
GCCATCGGCGAAGTCGCCGTGCCGGCCATGCGCAACAGCTTCTACAAGCTCGAACGCTCCGCCGACGTGATCGGCTGGGA
CCCGATCTGAGGGGCTGCGC

Downstream 100 bases:

>100_bases
GATGACCACCCCGTATATCGCCGCCCCGTTCCCAGCCCCGGAGGAACGCCCCGACAACGCACGCTTCTGGCAGGCCGCCC
GCGAGGGACGGCTGTTGGTC

Product: acetyl-CoA acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MSIKGKAYIVGAYEHPTRKAPDKSVAQLHAECARGALEDAGLSLSDVDGYFCAGDAPGLGATNMIDYLGLRVRHVDSTDT
GGSAYLVHVSHAAQAIAAGKCNVALITLAGRPRSEGSSGTQARNWGANLPDAPFEAPFHPVTVNLYAMVAMRHMHEYGTT
PEQLAWIKVAASHHAQHNPHAMLRDVVTVEDVLNSPLISDPLRKLDCCVVSDGGGALIVACPEIAAKLKRPKVRILGAGE
HVKGQLGGQVDLSWSAARVSGAAAFAEAGITPADIKYASIYDSFTITVLMQLEDLGFCKKGEGGRFVADGNLISGVGRLP
FNTDGGGLCNNHPANRGGITKVIEAVRQLRGEAHPAVQVKHCDLALAQGTGGYLGSRHGSATLILEREQ

Sequences:

>Translated_389_residues
MSIKGKAYIVGAYEHPTRKAPDKSVAQLHAECARGALEDAGLSLSDVDGYFCAGDAPGLGATNMIDYLGLRVRHVDSTDT
GGSAYLVHVSHAAQAIAAGKCNVALITLAGRPRSEGSSGTQARNWGANLPDAPFEAPFHPVTVNLYAMVAMRHMHEYGTT
PEQLAWIKVAASHHAQHNPHAMLRDVVTVEDVLNSPLISDPLRKLDCCVVSDGGGALIVACPEIAAKLKRPKVRILGAGE
HVKGQLGGQVDLSWSAARVSGAAAFAEAGITPADIKYASIYDSFTITVLMQLEDLGFCKKGEGGRFVADGNLISGVGRLP
FNTDGGGLCNNHPANRGGITKVIEAVRQLRGEAHPAVQVKHCDLALAQGTGGYLGSRHGSATLILEREQ
>Mature_388_residues
SIKGKAYIVGAYEHPTRKAPDKSVAQLHAECARGALEDAGLSLSDVDGYFCAGDAPGLGATNMIDYLGLRVRHVDSTDTG
GSAYLVHVSHAAQAIAAGKCNVALITLAGRPRSEGSSGTQARNWGANLPDAPFEAPFHPVTVNLYAMVAMRHMHEYGTTP
EQLAWIKVAASHHAQHNPHAMLRDVVTVEDVLNSPLISDPLRKLDCCVVSDGGGALIVACPEIAAKLKRPKVRILGAGEH
VKGQLGGQVDLSWSAARVSGAAAFAEAGITPADIKYASIYDSFTITVLMQLEDLGFCKKGEGGRFVADGNLISGVGRLPF
NTDGGGLCNNHPANRGGITKVIEAVRQLRGEAHPAVQVKHCDLALAQGTGGYLGSRHGSATLILEREQ

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=361, Percent_Identity=27.7008310249307, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI302344762, Length=228, Percent_Identity=30.7017543859649, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI302344760, Length=228, Percent_Identity=30.7017543859649, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI302344767, Length=228, Percent_Identity=30.7017543859649, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI55956775, Length=208, Percent_Identity=29.8076923076923, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17537653, Length=391, Percent_Identity=26.0869565217391, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI19921506, Length=398, Percent_Identity=28.1407035175879, Blast_Score=125, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24585051, Length=396, Percent_Identity=28.030303030303, Blast_Score=123, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: NA

Molecular weight: Translated: 40875; Mature: 40744

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKGKAYIVGAYEHPTRKAPDKSVAQLHAECARGALEDAGLSLSDVDGYFCAGDAPGLG
CCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCHHHCCCCEECCCCEEECCCCCCCC
ATNMIDYLGLRVRHVDSTDTGGSAYLVHVSHAAQAIAAGKCNVALITLAGRPRSEGSSGT
HHHHHHHHCEEEEEECCCCCCCEEEEEEECHHHHHHHCCCCCEEEEEECCCCCCCCCCCC
QARNWGANLPDAPFEAPFHPVTVNLYAMVAMRHMHEYGTTPEQLAWIKVAASHHAQHNPH
CCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCHHHEEEEEEEHHHCCCCCCH
AMLRDVVTVEDVLNSPLISDPLRKLDCCVVSDGGGALIVACPEIAAKLKRPKVRILGAGE
HHHHHHHHHHHHHCCCCHHCHHHHCCEEEEECCCCEEEEECHHHHHHHCCCEEEEEECCC
HVKGQLGGQVDLSWSAARVSGAAAFAEAGITPADIKYASIYDSFTITVLMQLEDLGFCKK
CCCCCCCCEEEECCHHHHHHHHHHHHHCCCCHHHEEEEEECCCEEEEEEEEEHHCCCCCC
GEGGRFVADGNLISGVGRLPFNTDGGGLCNNHPANRGGITKVIEAVRQLRGEAHPAVQVK
CCCCEEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEE
HCDLALAQGTGGYLGSRHGSATLILEREQ
ECCEEEECCCCCCCCCCCCCEEEEEEECC
>Mature Secondary Structure 
SIKGKAYIVGAYEHPTRKAPDKSVAQLHAECARGALEDAGLSLSDVDGYFCAGDAPGLG
CCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCHHHCCCCEECCCCEEECCCCCCCC
ATNMIDYLGLRVRHVDSTDTGGSAYLVHVSHAAQAIAAGKCNVALITLAGRPRSEGSSGT
HHHHHHHHCEEEEEECCCCCCCEEEEEEECHHHHHHHCCCCCEEEEEECCCCCCCCCCCC
QARNWGANLPDAPFEAPFHPVTVNLYAMVAMRHMHEYGTTPEQLAWIKVAASHHAQHNPH
CCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCHHHEEEEEEEHHHCCCCCCH
AMLRDVVTVEDVLNSPLISDPLRKLDCCVVSDGGGALIVACPEIAAKLKRPKVRILGAGE
HHHHHHHHHHHHHCCCCHHCHHHHCCEEEEECCCCEEEEECHHHHHHHCCCEEEEEECCC
HVKGQLGGQVDLSWSAARVSGAAAFAEAGITPADIKYASIYDSFTITVLMQLEDLGFCKK
CCCCCCCCEEEECCHHHHHHHHHHHHHCCCCHHHEEEEEECCCEEEEEEEEEHHCCCCCC
GEGGRFVADGNLISGVGRLPFNTDGGGLCNNHPANRGGITKVIEAVRQLRGEAHPAVQVK
CCCCEEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEE
HCDLALAQGTGGYLGSRHGSATLILEREQ
ECCEEEECCCCCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]