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The map label for this gene is kdgR [H]

Identifier: 94313319

GI number: 94313319

Start: 991122

End: 992132

Strand: Reverse

Name: kdgR [H]

Synonym: Rmet_4394

Alternate gene names: 94313319

Gene position: 992132-991122 (Counterclockwise)

Preceding gene: 94313321

Following gene: 94313297

Centisome position: 38.45

GC content: 65.18

Gene sequence:

>1011_bases
ATGGCAGTCCCCGCCAGGATGGCGGAGATTCTCACACGTCACTCTAAGCGTGGAGGTTGTTGTTGCTTTGATGTAGCGCA
AACTCGCTCCAGTCTTAAATCTAGCCGACTCCGGGAACCTGCGCTTGCGGCATTGCAGCCACCCAGCCAGCCACATCGAC
CGGACATTCGGGCCCGTGCTACAGTCCGCCGGGTATCAGACGCCACATTCAGACGCCCCAAGACTCCGCCCGCCATGCCA
GAGCGCCCCGCCCCTTCCGCTGCCAAACCGTCGTCGATGAACGTCAAGACGGCGCTGCGCGTCATCGAAATCATCGAAAC
GTTCGCACGCGAGCGCCGGGCGTTGTCGCTGTCGGAACTGGCCCGCCTGCTGGCCGTGCCGGCGTCGAGCTGTCTGGCGC
TGATCCGCACGCTGACCTCGCTCGGCTATCTCTACGAAACCGCGCGCCGCCAAGGCTACTACCCCACCGGCCGCCTGCTG
GCGATGGCGCAGCAGATTGCTCGCCACGATCCGGTGCTGGATCGCGTGCACGGCACGATGAGCGAGTTGCGTGACGCCAC
CGGCGAAACCATCGTCATCGGCAAACTGCATGAAGGGCAGGCGGTGGTGTATCTGGATGTGCTTGAATCACCACATGCGA
TTCGATACATCGCCACGGCGGGCGAGCGCCGCGAGCTTCATGCCAATTCGATCGGCAAGGCCCTGCTGGCGGCGATGGAC
GAGGCCGAACGCGCGACGCTGCTCGCGCAACTGCCCTTCCAGGCGTTCACCTCGCGCACGCTGACCACGCCCGCCGCGCT
GGAGGCGGATCTGCAGCAGGCGCGCGAACGCGGCGCTTACGTGAACCTGAGCGAGTCGATGCCCGACGTGGGGGCGCTGG
CATGGCCGGTGCGGCTGTCCGGCGAGTGCTACGCAATTTCGATTGCGGGTCCGGTCTACCGGATCGAACCGCACCTCGAC
CGCTATGCGCCAATGCTGCGCGCCGCCTGTGCGGCACTGGAAAAAACCTGA

Upstream 100 bases:

>100_bases
GCGCGGGCCAGCCGGACGGCTTCGTCCAGCGCGCGGGACGAGCAGTGGCTATCGTCGATCGGGACCATGATGTTGCGATA
CATGTGGGGCTCCTTTTGGA

Downstream 100 bases:

>100_bases
GCGGAATCAGTCGGCGGCGTCGCGCTCGCGCAGCCGCCAACCGGTGGCATCCGGCAAGCCCAATCCGTCCACGGGCGCGG
AAGCCGCCAACGCCAGCACG

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MAVPARMAEILTRHSKRGGCCCFDVAQTRSSLKSSRLREPALAALQPPSQPHRPDIRARATVRRVSDATFRRPKTPPAMP
ERPAPSAAKPSSMNVKTALRVIEIIETFARERRALSLSELARLLAVPASSCLALIRTLTSLGYLYETARRQGYYPTGRLL
AMAQQIARHDPVLDRVHGTMSELRDATGETIVIGKLHEGQAVVYLDVLESPHAIRYIATAGERRELHANSIGKALLAAMD
EAERATLLAQLPFQAFTSRTLTTPAALEADLQQARERGAYVNLSESMPDVGALAWPVRLSGECYAISIAGPVYRIEPHLD
RYAPMLRAACAALEKT

Sequences:

>Translated_336_residues
MAVPARMAEILTRHSKRGGCCCFDVAQTRSSLKSSRLREPALAALQPPSQPHRPDIRARATVRRVSDATFRRPKTPPAMP
ERPAPSAAKPSSMNVKTALRVIEIIETFARERRALSLSELARLLAVPASSCLALIRTLTSLGYLYETARRQGYYPTGRLL
AMAQQIARHDPVLDRVHGTMSELRDATGETIVIGKLHEGQAVVYLDVLESPHAIRYIATAGERRELHANSIGKALLAAMD
EAERATLLAQLPFQAFTSRTLTTPAALEADLQQARERGAYVNLSESMPDVGALAWPVRLSGECYAISIAGPVYRIEPHLD
RYAPMLRAACAALEKT
>Mature_335_residues
AVPARMAEILTRHSKRGGCCCFDVAQTRSSLKSSRLREPALAALQPPSQPHRPDIRARATVRRVSDATFRRPKTPPAMPE
RPAPSAAKPSSMNVKTALRVIEIIETFARERRALSLSELARLLAVPASSCLALIRTLTSLGYLYETARRQGYYPTGRLLA
MAQQIARHDPVLDRVHGTMSELRDATGETIVIGKLHEGQAVVYLDVLESPHAIRYIATAGERRELHANSIGKALLAAMDE
AERATLLAQLPFQAFTSRTLTTPAALEADLQQARERGAYVNLSESMPDVGALAWPVRLSGECYAISIAGPVYRIEPHLDR
YAPMLRAACAALEKT

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=240, Percent_Identity=28.3333333333333, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87082359, Length=250, Percent_Identity=26.8, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786468, Length=203, Percent_Identity=27.5862068965517, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1786715, Length=244, Percent_Identity=27.8688524590164, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790752, Length=224, Percent_Identity=29.9107142857143, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 36823; Mature: 36692

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVPARMAEILTRHSKRGGCCCFDVAQTRSSLKSSRLREPALAALQPPSQPHRPDIRARA
CCCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCHHHHH
TVRRVSDATFRRPKTPPAMPERPAPSAAKPSSMNVKTALRVIEIIETFARERRALSLSEL
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
ARLLAVPASSCLALIRTLTSLGYLYETARRQGYYPTGRLLAMAQQIARHDPVLDRVHGTM
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHH
SELRDATGETIVIGKLHEGQAVVYLDVLESPHAIRYIATAGERRELHANSIGKALLAAMD
HHHHHCCCCEEEEEEECCCCEEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
EAERATLLAQLPFQAFTSRTLTTPAALEADLQQARERGAYVNLSESMPDVGALAWPVRLS
HHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEECEEEC
GECYAISIAGPVYRIEPHLDRYAPMLRAACAALEKT
CCEEEEEECCCEEEECCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AVPARMAEILTRHSKRGGCCCFDVAQTRSSLKSSRLREPALAALQPPSQPHRPDIRARA
CCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCHHHHH
TVRRVSDATFRRPKTPPAMPERPAPSAAKPSSMNVKTALRVIEIIETFARERRALSLSEL
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
ARLLAVPASSCLALIRTLTSLGYLYETARRQGYYPTGRLLAMAQQIARHDPVLDRVHGTM
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHH
SELRDATGETIVIGKLHEGQAVVYLDVLESPHAIRYIATAGERRELHANSIGKALLAAMD
HHHHHCCCCEEEEEEECCCCEEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
EAERATLLAQLPFQAFTSRTLTTPAALEADLQQARERGAYVNLSESMPDVGALAWPVRLS
HHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEECEEEC
GECYAISIAGPVYRIEPHLDRYAPMLRAACAALEKT
CCEEEEEECCCEEEECCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]