Click here to switch to the map view.

The map label for this gene is oxlT [H]

Identifier: 94313294

GI number: 94313294

Start: 966998

End: 968323

Strand: Direct

Name: oxlT [H]

Synonym: Rmet_4369

Alternate gene names: 94313294

Gene position: 966998-968323 (Clockwise)

Preceding gene: 94313293

Following gene: 94313295

Centisome position: 37.48

GC content: 62.14

Gene sequence:

>1326_bases
ATGGAACCTCAGCAGAACGGAAGCGCGCCGACGTCATGGTTTGCATCGCCATGGACGCAGCTCGTGTTCGGTGTGATCTG
CATGGCGATGATTGCCAACATGCAGTACGGCTGGACGTTGTTCGTCAATCCGATTGACGAGAAGTACCACTGGGGTCGCA
CCGCGATCCAGGTGGCATTCACGATCTTCGTGGTCACGGAGACCTGGCTGGTGCCCATCGAAGGGTATCTGGTCGACAAG
TACGGGCCACGCCCGGTGGTTGTTGGTGGCGGCCTGCTTTGCGCGGTGGCCTGGGCGTTGAACTCGGTGGCCTCATCGTT
GCCGATGCTGTACTTCGCGGCAGCGGTGGGTGGCGTCGGGGCCGGGGCGGTCTACGGGACCTGCGTCGGCAATGCGCTCA
AGTGGTTCCCGAATCGTCGAGGGCTGGCGGCGGGACTGACGGCCGCGGGTTTCGGCGCGGGTTCCGCCGCCACCGTGGTG
CCAATTGCCAACATGATCAAGTCCAGCGGCTACGAGGCCACGTTCCTGTGGTTTGGGCTCGGGCAGGGGATCGTTGTGGT
GATGCTCGGCATGTTGCTCTATCCGCCGTCGGCCAAGATCCTCTCGGATGTAAAGAGTACGCTGAAGGCTGCGGCCACCT
ACAACGCCACGCCGCGCCAGGTGCTGTCCTCGCCGATTTTCTGGGTCATGTACGCCATGTTCGTGATGATGGCGGCGGGC
GGACTGATGGCAACGGCGCAGCTTGGGCCCATCGCCAAGGACTTCGGTCTGCACGACTCGCCGGTCTCCATCCTTGGTCT
GACCCTGCCAGCGTTGACCTTCGCGCTGACCATCGACCGTGTGCTAAATGGTCTGACACGCCCGTTTTTCGGCTGGATTT
CCGACAACATTGGTCGCGAGAACACCATGTTCCTGGCGTTCGCGGTCGAAGCCGTCGGCATCCTGCTGCTGGCCAAGTAT
GGGCAGAACCCAACGGCGTTTGTGATCCTGACCGGCATCGTGTTCTTCGCCTGGGGCGAAATCTATAGTCTGTTCCCGGC
GACGTGCGGCGATACCTTCGGACCGAAGTTCGCCGCGACCAATGCAGGGCTGCTCTACACTGCGAAAGGCACCGCCGCAC
TGCTGGTGCCGTTCTCCAGTGTCATTACGGCGGCAACGGGCGACTGGTATGCAGTGTTCATGCTGGCGTCCGGCATGGCA
GCGGTTTCGGCCCTGATGGCAATCTTCGTACTCAAGCCGATGCGTGAAGCCCATGCGAGGAGATTTGTCCAGGATAGCGC
GGGCGCGCCGATGGGATACCGTCCTGTACCGGAGGACCTGACCTGA

Upstream 100 bases:

>100_bases
AGCTGTTCGAGATCAGCAGGGTGAAGCGACGCGATACACCAGAGGCATCTCCGCAGATGCCCATCCACAACGGCGACCAA
GGTTGCCAGAAGGAGACACC

Downstream 100 bases:

>100_bases
GTGAGTGCGCTGTAAAACCTTGGCCCGCCTCGTGCGGGCTTTTTTGTCGTTCTATTTTCCCGATATGCGGGAAAGTGATT
GCGGGATCTTCCGGCTAATC

Product: major facilitator superfamily transporter

Products: NA

Alternate protein names: OFA; Oxalate:formate antiport protein; Oxalate:formate exchange protein [H]

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MEPQQNGSAPTSWFASPWTQLVFGVICMAMIANMQYGWTLFVNPIDEKYHWGRTAIQVAFTIFVVTETWLVPIEGYLVDK
YGPRPVVVGGGLLCAVAWALNSVASSLPMLYFAAAVGGVGAGAVYGTCVGNALKWFPNRRGLAAGLTAAGFGAGSAATVV
PIANMIKSSGYEATFLWFGLGQGIVVVMLGMLLYPPSAKILSDVKSTLKAAATYNATPRQVLSSPIFWVMYAMFVMMAAG
GLMATAQLGPIAKDFGLHDSPVSILGLTLPALTFALTIDRVLNGLTRPFFGWISDNIGRENTMFLAFAVEAVGILLLAKY
GQNPTAFVILTGIVFFAWGEIYSLFPATCGDTFGPKFAATNAGLLYTAKGTAALLVPFSSVITAATGDWYAVFMLASGMA
AVSALMAIFVLKPMREAHARRFVQDSAGAPMGYRPVPEDLT

Sequences:

>Translated_441_residues
MEPQQNGSAPTSWFASPWTQLVFGVICMAMIANMQYGWTLFVNPIDEKYHWGRTAIQVAFTIFVVTETWLVPIEGYLVDK
YGPRPVVVGGGLLCAVAWALNSVASSLPMLYFAAAVGGVGAGAVYGTCVGNALKWFPNRRGLAAGLTAAGFGAGSAATVV
PIANMIKSSGYEATFLWFGLGQGIVVVMLGMLLYPPSAKILSDVKSTLKAAATYNATPRQVLSSPIFWVMYAMFVMMAAG
GLMATAQLGPIAKDFGLHDSPVSILGLTLPALTFALTIDRVLNGLTRPFFGWISDNIGRENTMFLAFAVEAVGILLLAKY
GQNPTAFVILTGIVFFAWGEIYSLFPATCGDTFGPKFAATNAGLLYTAKGTAALLVPFSSVITAATGDWYAVFMLASGMA
AVSALMAIFVLKPMREAHARRFVQDSAGAPMGYRPVPEDLT
>Mature_441_residues
MEPQQNGSAPTSWFASPWTQLVFGVICMAMIANMQYGWTLFVNPIDEKYHWGRTAIQVAFTIFVVTETWLVPIEGYLVDK
YGPRPVVVGGGLLCAVAWALNSVASSLPMLYFAAAVGGVGAGAVYGTCVGNALKWFPNRRGLAAGLTAAGFGAGSAATVV
PIANMIKSSGYEATFLWFGLGQGIVVVMLGMLLYPPSAKILSDVKSTLKAAATYNATPRQVLSSPIFWVMYAMFVMMAAG
GLMATAQLGPIAKDFGLHDSPVSILGLTLPALTFALTIDRVLNGLTRPFFGWISDNIGRENTMFLAFAVEAVGILLLAKY
GQNPTAFVILTGIVFFAWGEIYSLFPATCGDTFGPKFAATNAGLLYTAKGTAALLVPFSSVITAATGDWYAVFMLASGMA
AVSALMAIFVLKPMREAHARRFVQDSAGAPMGYRPVPEDLT

Specific function: Anion transporter that carries out the exchange of divalent oxalate with monovalent formate, the product of oxalate decarboxylation, at the plasma membrane, and in doing so catalyzes the vectorial portion of a proton-motive metabolic cycle that drives ATP

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. OFA (TC 2.A.1.11) family [H]

Homologues:

Organism=Homo sapiens, GI24431958, Length=436, Percent_Identity=22.7064220183486, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1789969, Length=414, Percent_Identity=23.4299516908213, Blast_Score=101, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004741 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46813; Mature: 46813

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPQQNGSAPTSWFASPWTQLVFGVICMAMIANMQYGWTLFVNPIDEKYHWGRTAIQVAF
CCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHCCHHHHHHHH
TIFVVTETWLVPIEGYLVDKYGPRPVVVGGGLLCAVAWALNSVASSLPMLYFAAAVGGVG
HHHEEEHHEEEEECCEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AGAVYGTCVGNALKWFPNRRGLAAGLTAAGFGAGSAATVVPIANMIKSSGYEATFLWFGL
CHHHHHHHHHHHHHHCCCCCCCHHCCHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEC
GQGIVVVMLGMLLYPPSAKILSDVKSTLKAAATYNATPRQVLSSPIFWVMYAMFVMMAAG
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHCC
GLMATAQLGPIAKDFGLHDSPVSILGLTLPALTFALTIDRVLNGLTRPFFGWISDNIGRE
CHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NTMFLAFAVEAVGILLLAKYGQNPTAFVILTGIVFFAWGEIYSLFPATCGDTFGPKFAAT
CCEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCC
NAGLLYTAKGTAALLVPFSSVITAATGDWYAVFMLASGMAAVSALMAIFVLKPMREAHAR
CCCEEEEECCCEEEEEEHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
RFVQDSAGAPMGYRPVPEDLT
HHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEPQQNGSAPTSWFASPWTQLVFGVICMAMIANMQYGWTLFVNPIDEKYHWGRTAIQVAF
CCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHCCHHHHHHHH
TIFVVTETWLVPIEGYLVDKYGPRPVVVGGGLLCAVAWALNSVASSLPMLYFAAAVGGVG
HHHEEEHHEEEEECCEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AGAVYGTCVGNALKWFPNRRGLAAGLTAAGFGAGSAATVVPIANMIKSSGYEATFLWFGL
CHHHHHHHHHHHHHHCCCCCCCHHCCHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEC
GQGIVVVMLGMLLYPPSAKILSDVKSTLKAAATYNATPRQVLSSPIFWVMYAMFVMMAAG
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHCC
GLMATAQLGPIAKDFGLHDSPVSILGLTLPALTFALTIDRVLNGLTRPFFGWISDNIGRE
CHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NTMFLAFAVEAVGILLLAKYGQNPTAFVILTGIVFFAWGEIYSLFPATCGDTFGPKFAAT
CCEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCC
NAGLLYTAKGTAALLVPFSSVITAATGDWYAVFMLASGMAAVSALMAIFVLKPMREAHAR
CCCEEEEECCCEEEEEEHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
RFVQDSAGAPMGYRPVPEDLT
HHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8636101; 9651403; 11919184; 11113128; 11274108; 11500368 [H]