BacMap

Definition	Cupriavidus metallidurans CH34 megaplasmid, complete sequence.
Accession	NC_007974
Length	2,580,084

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The map label for this gene is fabG [H]

Identifier: 94313244

GI number: 94313244

Start: 914046

End: 914765

Strand: Direct

Name: fabG [H]

Synonym: Rmet_4319

Alternate gene names: 94313244

Gene position: 914046-914765 (Clockwise)

Preceding gene: 94313236

Following gene: 94313245

Centisome position: 35.43

GC content: 62.5

Gene sequence:

>720_bases
ATGTCACACAAGACTTTCCTGATCACCGGTGCGAGCAAGGGAATCGGCCGGGCGTTGTCCCATCGCCTGGCGGCTGCCGG
GCACAAAGTGATCGGCGTCGCGCGTAACGCCGACCCCGGTTTCCCCGGCATTCTGGTGCCCATCGATCTCACGGACCCGG
TTGCCACTGAACATGCGCTGACGACACTGAGGTCCGAGCACGTGATCGACGGTGTCGTGAACAACGTGGGGTTCATCGAG
CTTGCGCCACTTGGCAATATCGACCTGGATGCCATGGACGACATGTTTCGGTCGAACCTGCGGCCAGCCGTTCAGCTTGT
CCAGGCGCTGTTGCCGGACATGCGGGAGCGGGGTTGGGGCCGTATCGTGAACCTGTCGAGCCTTGTCGTGCTGGGCGTTG
CGAACCGCTCCGTCTATGCCGCGGCCAAAAGCGCCATGATCAGCTTCACACGAACGTGGGCACTCGAACTCGCACCCACC
GGGATCACGGTGAATGCGGTCGCGCCGGGGCCTGTTGAAACCGAAATGTTCCGTGCCAATACGCCACAGGGCAGCGATGC
GGAGAAGCGATTTCTGTCCATGGTGCCGATGGGGCGTCTGGGCAAGCCGGATGAACTGGCCGCCGCGATCGAATTCCTGC
TTTCCGAGCCTGCCGGCTTTATTACGGGGCAGACGCTGTTCGTGGATGGCGGCGCGTCGATTGGCAAGGCAGCGCTCTAG

Upstream 100 bases:

>100_bases
GTTCGTTGTGTTTTGTATCGATCGATCTATAATAATTTCGTAGCAATCGATACAAAATTGGCCGAAGCGAGGGCGCTCCG
GCACGGAACCTGGATATGCA

Downstream 100 bases:

>100_bases
CGCCCGGGACAGTGCCCCGTAGTCTTGCGATGGAAGGGCATGTTGCGGAGACGGCCGGTGGCACCGCCGAAGGCCGGCGA
GACATCTTGTGGCCTCGTTG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MSHKTFLITGASKGIGRALSHRLAAAGHKVIGVARNADPGFPGILVPIDLTDPVATEHALTTLRSEHVIDGVVNNVGFIE
LAPLGNIDLDAMDDMFRSNLRPAVQLVQALLPDMRERGWGRIVNLSSLVVLGVANRSVYAAAKSAMISFTRTWALELAPT
GITVNAVAPGPVETEMFRANTPQGSDAEKRFLSMVPMGRLGKPDELAAAIEFLLSEPAGFITGQTLFVDGGASIGKAAL

Sequences:

>Translated_239_residues
MSHKTFLITGASKGIGRALSHRLAAAGHKVIGVARNADPGFPGILVPIDLTDPVATEHALTTLRSEHVIDGVVNNVGFIE
LAPLGNIDLDAMDDMFRSNLRPAVQLVQALLPDMRERGWGRIVNLSSLVVLGVANRSVYAAAKSAMISFTRTWALELAPT
GITVNAVAPGPVETEMFRANTPQGSDAEKRFLSMVPMGRLGKPDELAAAIEFLLSEPAGFITGQTLFVDGGASIGKAAL
>Mature_238_residues
SHKTFLITGASKGIGRALSHRLAAAGHKVIGVARNADPGFPGILVPIDLTDPVATEHALTTLRSEHVIDGVVNNVGFIEL
APLGNIDLDAMDDMFRSNLRPAVQLVQALLPDMRERGWGRIVNLSSLVVLGVANRSVYAAAKSAMISFTRTWALELAPTG
ITVNAVAPGPVETEMFRANTPQGSDAEKRFLSMVPMGRLGKPDELAAAIEFLLSEPAGFITGQTLFVDGGASIGKAAL

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705925, Length=240, Percent_Identity=38.75, Blast_Score=120, Evalue=7e-28,
Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=32.6446280991736, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI32483357, Length=261, Percent_Identity=27.9693486590038, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI15277342, Length=247, Percent_Identity=30.7692307692308, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI66933014, Length=223, Percent_Identity=28.6995515695067, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI19923817, Length=249, Percent_Identity=29.3172690763052, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI7657478, Length=189, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI109715829, Length=238, Percent_Identity=31.0924369747899, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI59889578, Length=205, Percent_Identity=34.1463414634146, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI126723750, Length=248, Percent_Identity=27.0161290322581, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=28.1124497991968, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI7706318, Length=187, Percent_Identity=32.620320855615, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI223718074, Length=194, Percent_Identity=31.4432989690722, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI10190704, Length=248, Percent_Identity=29.0322580645161, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787335, Length=238, Percent_Identity=39.4957983193277, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=32.1428571428571, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1786812, Length=248, Percent_Identity=29.8387096774194, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=30.8943089430894, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1786701, Length=191, Percent_Identity=34.5549738219895, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788459, Length=241, Percent_Identity=32.3651452282158, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI87082160, Length=243, Percent_Identity=29.6296296296296, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789208, Length=258, Percent_Identity=28.2945736434109, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI2367365, Length=231, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=29.5081967213115, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787820, Length=225, Percent_Identity=28, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787905, Length=246, Percent_Identity=29.2682926829268, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789378, Length=254, Percent_Identity=25.9842519685039, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=245, Percent_Identity=36.3265306122449, Blast_Score=119, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=34.2741935483871, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17555706, Length=243, Percent_Identity=34.156378600823, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=31.5589353612167, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=32.1285140562249, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=32.6996197718631, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17565030, Length=257, Percent_Identity=31.9066147859922, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=31.4393939393939, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=29.4339622641509, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=29.0322580645161, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17544670, Length=263, Percent_Identity=29.277566539924, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17563726, Length=260, Percent_Identity=30.7692307692308, Blast_Score=93, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=30.7692307692308, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=31.1538461538462, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17538486, Length=263, Percent_Identity=30.0380228136882, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17561402, Length=248, Percent_Identity=29.0322580645161, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI193204405, Length=261, Percent_Identity=33.3333333333333, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=31.6793893129771, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=32.183908045977, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=32.319391634981, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17531453, Length=261, Percent_Identity=31.8007662835249, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI25147288, Length=243, Percent_Identity=29.6296296296296, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=30.4182509505703, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI72000259, Length=261, Percent_Identity=29.5019157088123, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=29.6577946768061, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17508651, Length=248, Percent_Identity=29.8387096774194, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17559552, Length=189, Percent_Identity=29.1005291005291, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=217, Percent_Identity=32.258064516129, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6324126, Length=245, Percent_Identity=23.265306122449, Blast_Score=63, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=36.9047619047619, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI23397609, Length=243, Percent_Identity=33.7448559670782, Blast_Score=110, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=32.3886639676113, Blast_Score=107, Evalue=6e-24,
Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=34.2629482071713, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=32.8, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21355319, Length=251, Percent_Identity=29.4820717131474, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24644339, Length=253, Percent_Identity=35.1778656126482, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24644337, Length=181, Percent_Identity=38.6740331491713, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21358495, Length=204, Percent_Identity=31.8627450980392, Blast_Score=85, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25204; Mature: 25073

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHKTFLITGASKGIGRALSHRLAAAGHKVIGVARNADPGFPGILVPIDLTDPVATEHAL
CCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEEEECCCCCHHHHHH
TTLRSEHVIDGVVNNVGFIELAPLGNIDLDAMDDMFRSNLRPAVQLVQALLPDMRERGWG
HHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCC
RIVNLSSLVVLGVANRSVYAAAKSAMISFTRTWALELAPTGITVNAVAPGPVETEMFRAN
EEEECCEEEEEEECCCHHHHHHHHHHHHHHHEEEEEEECCCEEEEECCCCCCCHHEEECC
TPQGSDAEKRFLSMVPMGRLGKPDELAAAIEFLLSEPAGFITGQTLFVDGGASIGKAAL
CCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEECCEEEEECCCCCCCCCC
>Mature Secondary Structure 
SHKTFLITGASKGIGRALSHRLAAAGHKVIGVARNADPGFPGILVPIDLTDPVATEHAL
CCCEEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEEEECCCCCHHHHHH
TTLRSEHVIDGVVNNVGFIELAPLGNIDLDAMDDMFRSNLRPAVQLVQALLPDMRERGWG
HHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCC
RIVNLSSLVVLGVANRSVYAAAKSAMISFTRTWALELAPTGITVNAVAPGPVETEMFRAN
EEEECCEEEEEEECCCHHHHHHHHHHHHHHHEEEEEEECCCEEEEECCCCCCCHHEEECC
TPQGSDAEKRFLSMVPMGRLGKPDELAAAIEFLLSEPAGFITGQTLFVDGGASIGKAAL
CCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEECCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1556094; 8905232; 9278503; 1314802 [H]