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The map label for this gene is mauR [H]

Identifier: 94313208

GI number: 94313208

Start: 873975

End: 874841

Strand: Direct

Name: mauR [H]

Synonym: Rmet_4282

Alternate gene names: 94313208

Gene position: 873975-874841 (Clockwise)

Preceding gene: 94313201

Following gene: 94313212

Centisome position: 33.87

GC content: 64.94

Gene sequence:

>867_bases
ATGAACTGGGACGACGCGCGCATCTTCGTTGCGCTCTATCGGGAACGGACGTTGCGCGCCGCCGCCCGCGCGCTCGACAT
CGACCAGGCGACGGTAGGCCGCAGGCTTGCGGTGCTCGAGCATGCACTTGGCTCGACCCTATTCCTGCGCACCTCGAATG
GCTATGAGCTCACACAGGTCGGCAAGCTCGCGATCCGCGCCGCGGAGGCGATGGAGCAGTCCGCGCACGATCTAGTGCGC
CACACTCAAGGCATGGACAAGCGCCTCGCCGGCGAGGTGAAGCTCTCGACGACGGACGCACTAGCGCAGGAGTACGTGGT
GCCGGCGATCGAGAGCCTGCATGCACAGCACCCCGACGTATCGGTGGTCCTCGACACGACGACGCATGTCCTCAATCTCG
CGAAGCGTGAAGCCGATATCGCGGTGCGAACCGTCAAGCCGCGAAACCCGGATCTGCTCGCGCGTCGTCTTGCGAGCTGG
GACGTGGGGCTGTTTGCCTCGCCAGCCTATATCCGGCGCCACGGCGAACCAGTACCCGGGGAGCGATTCCTGGGGCACGA
TCTTGTCGTCTATCAGCCGCATTTCGCCAAGGCGCGCGCGCCGTCGTTCATTGGAGAACCGCTGACGGATGGCCGTATCG
CCGCAAGACTGAACACGAACCTGACTCTGCGCGCGGCACTCAAGGCCGGCCTCGGCATCAGCGAGATTCCCGTTCCGATG
GGCGAACGCGATGGTCTCGTGCGGATCTGGCCAGACCGCACTAGCGGTGCACCGTATGAGGTCTGGCTCGTAACGCATCA
GGATCTGCGGCACACCGCGCGCGTCCGCGTGACGATCGACGAGATCGTCCTGGCGTTCGGTCGATAG

Upstream 100 bases:

>100_bases
CGGTGCATCGTTGAAGCAAAGTGTAGGGAGGCTGCCGGTCCTTTGACACGCAGCGATTTGCTGGTCGTATGATGCAAATT
TGCATCATGCGGGAGGCGAC

Downstream 100 bases:

>100_bases
CAGCGCAGGCGCGGCCTCGTTACGACGGATGTCTTTCCGATGCGGCTGTGCATGGGGACGAATTGCTTTTGGGCGGCGAC
GTGCAACCACGGAACCCGCA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MNWDDARIFVALYRERTLRAAARALDIDQATVGRRLAVLEHALGSTLFLRTSNGYELTQVGKLAIRAAEAMEQSAHDLVR
HTQGMDKRLAGEVKLSTTDALAQEYVVPAIESLHAQHPDVSVVLDTTTHVLNLAKREADIAVRTVKPRNPDLLARRLASW
DVGLFASPAYIRRHGEPVPGERFLGHDLVVYQPHFAKARAPSFIGEPLTDGRIAARLNTNLTLRAALKAGLGISEIPVPM
GERDGLVRIWPDRTSGAPYEVWLVTHQDLRHTARVRVTIDEIVLAFGR

Sequences:

>Translated_288_residues
MNWDDARIFVALYRERTLRAAARALDIDQATVGRRLAVLEHALGSTLFLRTSNGYELTQVGKLAIRAAEAMEQSAHDLVR
HTQGMDKRLAGEVKLSTTDALAQEYVVPAIESLHAQHPDVSVVLDTTTHVLNLAKREADIAVRTVKPRNPDLLARRLASW
DVGLFASPAYIRRHGEPVPGERFLGHDLVVYQPHFAKARAPSFIGEPLTDGRIAARLNTNLTLRAALKAGLGISEIPVPM
GERDGLVRIWPDRTSGAPYEVWLVTHQDLRHTARVRVTIDEIVLAFGR
>Mature_288_residues
MNWDDARIFVALYRERTLRAAARALDIDQATVGRRLAVLEHALGSTLFLRTSNGYELTQVGKLAIRAAEAMEQSAHDLVR
HTQGMDKRLAGEVKLSTTDALAQEYVVPAIESLHAQHPDVSVVLDTTTHVLNLAKREADIAVRTVKPRNPDLLARRLASW
DVGLFASPAYIRRHGEPVPGERFLGHDLVVYQPHFAKARAPSFIGEPLTDGRIAARLNTNLTLRAALKAGLGISEIPVPM
GERDGLVRIWPDRTSGAPYEVWLVTHQDLRHTARVRVTIDEIVLAFGR

Specific function: Transcriptional activator of the mau genes involved in methylamine metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=285, Percent_Identity=24.2105263157895, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI87081978, Length=301, Percent_Identity=24.5847176079734, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1786401, Length=281, Percent_Identity=23.1316725978648, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI145693193, Length=235, Percent_Identity=22.9787234042553, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787601, Length=184, Percent_Identity=25.5434782608696, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1789639, Length=286, Percent_Identity=21.6783216783217, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31928; Mature: 31928

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS50931 HTH_LYSR ; PS00307 LECTIN_LEGUME_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWDDARIFVALYRERTLRAAARALDIDQATVGRRLAVLEHALGSTLFLRTSNGYELTQV
CCCCHHEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHH
GKLAIRAAEAMEQSAHDLVRHTQGMDKRLAGEVKLSTTDALAQEYVVPAIESLHAQHPDV
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCEEECHHHHHHHHHHHHHHHHHHCCCCCE
SVVLDTTTHVLNLAKREADIAVRTVKPRNPDLLARRLASWDVGLFASPAYIRRHGEPVPG
EEEECCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCC
ERFLGHDLVVYQPHFAKARAPSFIGEPLTDGRIAARLNTNLTLRAALKAGLGISEIPVPM
CCCCCCCEEEECCCCHHHCCCCCCCCCCCCCEEEEEECCCEEEEEHHHHCCCCCCCCCCC
GERDGLVRIWPDRTSGAPYEVWLVTHQDLRHTARVRVTIDEIVLAFGR
CCCCCEEEECCCCCCCCCEEEEEEECHHHCCCEEEEEEHHHHHHHCCC
>Mature Secondary Structure
MNWDDARIFVALYRERTLRAAARALDIDQATVGRRLAVLEHALGSTLFLRTSNGYELTQV
CCCCHHEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHH
GKLAIRAAEAMEQSAHDLVRHTQGMDKRLAGEVKLSTTDALAQEYVVPAIESLHAQHPDV
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCEEECHHHHHHHHHHHHHHHHHHCCCCCE
SVVLDTTTHVLNLAKREADIAVRTVKPRNPDLLARRLASWDVGLFASPAYIRRHGEPVPG
EEEECCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCC
ERFLGHDLVVYQPHFAKARAPSFIGEPLTDGRIAARLNTNLTLRAALKAGLGISEIPVPM
CCCCCCCEEEECCCCHHHCCCCCCCCCCCCCEEEEEECCCEEEEEHHHHCCCCCCCCCCC
GERDGLVRIWPDRTSGAPYEVWLVTHQDLRHTARVRVTIDEIVLAFGR
CCCCCEEEECCCCCCCCCEEEEEEECHHHCCCEEEEEEHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7957249 [H]