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The map label for this gene is qor [H]

Identifier: 94313207

GI number: 94313207

Start: 872785

End: 873819

Strand: Reverse

Name: qor [H]

Synonym: Rmet_4281

Alternate gene names: 94313207

Gene position: 873819-872785 (Counterclockwise)

Preceding gene: 94313209

Following gene: 94313206

Centisome position: 33.87

GC content: 62.51

Gene sequence:

>1035_bases
ATGACACACGCAACGCATACCATTCCTGCAGCAATGGTCGCAATCGAGATCACGCAACCAGGGGGGCCCGATGTTCTTGC
GCCGGTGCAGCGGCCAGTTCCCGTGCCGGCAGCCGACGAAGTATTGATCCGCATTCATGCCGCCGGCGTGAACGGCCCCG
ATGTCATGCAGCGCAGGGGCTTGTATGATCCGCCACCGGGTGCCTCGGACATCCCCGGACTCGAAGTCGCAGGCGAGATC
GTGTCCGTCGGGCGCGACGTGATCCGGTTCGCAGTAGGCGACCTCGTCTGCGCACTGGTCCCGGGCGGCGGCTACGCGGA
GTACGCAGTCGCGCATGAGAGCAATACGCTGACGATTCCGGAGGGTCTCTCAATGGTTGAGGCAGCTGCGCTGCCGGAGA
CCTTTCTAACGGTATGGCTGAATCTGTTCCAGCGCGGCAAGTTCTCGGCAGGCGAAAGCGTGCTTATCCACGGCGGCGCA
TCCGGGATCGGCACCACGGCGACGATGCTTGCAAAAGCGTTTGGCGCATCAAAGATCATCACGACAGTCGGCTCCGATAC
CCAGCGCGACGCGAGCATTGCGCTGGGCGCCGATGTCGCCGTGGATTACCGCAACGAGGATTTCGTCGAGGCGGTAGCAC
GCGCGACGGACGGGCGTGGCGTCGACGTGGTTGTCGATATCATTGCCGGCGACTACGTCGCGCGCAATTACGCAGCGGCT
GCGATGGACGGCCGCATTGTCCAGATCGGCGTGATCAAGGGTCCGGCGCAGTCACTCGACTTATTCCCGATGCTGGCGAA
GCGTCTCACGCACATCGGCTCAACGCTGCGCTCGCGCACACACGAGGAAAAGGCGGTGTTGATCGAGGATCTCGAACAAT
CTGTTTTTCCGCACATTCGGCGCGGCGCGGTGAAGCCAGTTATGTACAAGACCTTCGATCTCGGCGATGCGCGCCGCGCG
CATGAGCTGATGGACTCAGGCACGCACATCGGCAAGATTGTGCTGACGACCCAAGCGGCGCACAGCGCTCCATAA

Upstream 100 bases:

>100_bases
CAAAGGACCGGCAGCCTCCCTACACTTTGCTTCAACGATGCACCGATCAAGCAAGTTGCTCGAATCCGCAGTGCATCCGG
CATTTTGAAAGGATGAACTC

Downstream 100 bases:

>100_bases
GCGTTTTCCAGCCCTCCCCGGTACCACGGTACCGCAAGCAACGTCGAGCATCTGCATCGCGATACCGGTGCGACCTATTG
CTGATCGAGTAGGTGCTATG

Product: alcohol dehydrogenase, zinc-binding

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MTHATHTIPAAMVAIEITQPGGPDVLAPVQRPVPVPAADEVLIRIHAAGVNGPDVMQRRGLYDPPPGASDIPGLEVAGEI
VSVGRDVIRFAVGDLVCALVPGGGYAEYAVAHESNTLTIPEGLSMVEAAALPETFLTVWLNLFQRGKFSAGESVLIHGGA
SGIGTTATMLAKAFGASKIITTVGSDTQRDASIALGADVAVDYRNEDFVEAVARATDGRGVDVVVDIIAGDYVARNYAAA
AMDGRIVQIGVIKGPAQSLDLFPMLAKRLTHIGSTLRSRTHEEKAVLIEDLEQSVFPHIRRGAVKPVMYKTFDLGDARRA
HELMDSGTHIGKIVLTTQAAHSAP

Sequences:

>Translated_344_residues
MTHATHTIPAAMVAIEITQPGGPDVLAPVQRPVPVPAADEVLIRIHAAGVNGPDVMQRRGLYDPPPGASDIPGLEVAGEI
VSVGRDVIRFAVGDLVCALVPGGGYAEYAVAHESNTLTIPEGLSMVEAAALPETFLTVWLNLFQRGKFSAGESVLIHGGA
SGIGTTATMLAKAFGASKIITTVGSDTQRDASIALGADVAVDYRNEDFVEAVARATDGRGVDVVVDIIAGDYVARNYAAA
AMDGRIVQIGVIKGPAQSLDLFPMLAKRLTHIGSTLRSRTHEEKAVLIEDLEQSVFPHIRRGAVKPVMYKTFDLGDARRA
HELMDSGTHIGKIVLTTQAAHSAP
>Mature_343_residues
THATHTIPAAMVAIEITQPGGPDVLAPVQRPVPVPAADEVLIRIHAAGVNGPDVMQRRGLYDPPPGASDIPGLEVAGEIV
SVGRDVIRFAVGDLVCALVPGGGYAEYAVAHESNTLTIPEGLSMVEAAALPETFLTVWLNLFQRGKFSAGESVLIHGGAS
GIGTTATMLAKAFGASKIITTVGSDTQRDASIALGADVAVDYRNEDFVEAVARATDGRGVDVVVDIIAGDYVARNYAAAA
MDGRIVQIGVIKGPAQSLDLFPMLAKRLTHIGSTLRSRTHEEKAVLIEDLEQSVFPHIRRGAVKPVMYKTFDLGDARRAH
ELMDSGTHIGKIVLTTQAAHSAP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=329, Percent_Identity=38.6018237082067, Blast_Score=228, Evalue=5e-60,
Organism=Homo sapiens, GI22538444, Length=329, Percent_Identity=38.6018237082067, Blast_Score=228, Evalue=5e-60,
Organism=Homo sapiens, GI194239674, Length=329, Percent_Identity=30.0911854103343, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI13236495, Length=329, Percent_Identity=30.0911854103343, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI24308257, Length=334, Percent_Identity=27.2455089820359, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI194239676, Length=329, Percent_Identity=28.8753799392097, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI18379349, Length=223, Percent_Identity=31.8385650224215, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI41872631, Length=308, Percent_Identity=28.2467532467532, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI28557745, Length=373, Percent_Identity=29.2225201072386, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI197927207, Length=199, Percent_Identity=25.6281407035176, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI47519420, Length=213, Percent_Identity=30.9859154929577, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1790485, Length=332, Percent_Identity=31.0240963855422, Blast_Score=117, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17507255, Length=330, Percent_Identity=25.1515151515152, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI212642053, Length=310, Percent_Identity=28.0645161290323, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71987554, Length=178, Percent_Identity=34.2696629213483, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319520, Length=334, Percent_Identity=27.5449101796407, Blast_Score=101, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6323961, Length=361, Percent_Identity=25.207756232687, Blast_Score=86, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6324486, Length=335, Percent_Identity=25.3731343283582, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319621, Length=334, Percent_Identity=23.6526946107784, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323729, Length=335, Percent_Identity=22.6865671641791, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19920632, Length=305, Percent_Identity=30.1639344262295, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI221330659, Length=305, Percent_Identity=30.1639344262295, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24581345, Length=344, Percent_Identity=26.1627906976744, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI45550423, Length=206, Percent_Identity=28.1553398058252, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 36146; Mature: 36015

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS00962 RIBOSOMAL_S2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHATHTIPAAMVAIEITQPGGPDVLAPVQRPVPVPAADEVLIRIHAAGVNGPDVMQRRG
CCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHCC
LYDPPPGASDIPGLEVAGEIVSVGRDVIRFAVGDLVCALVPGGGYAEYAVAHESNTLTIP
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEEECCCEEECC
EGLSMVEAAALPETFLTVWLNLFQRGKFSAGESVLIHGGASGIGTTATMLAKAFGASKII
CCCHHHHHHHCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCEE
TTVGSDTQRDASIALGADVAVDYRNEDFVEAVARATDGRGVDVVVDIIAGDYVARNYAAA
EECCCCCCCCCEEEECCEEEEECCCHHHHHHHHHHCCCCCCEEEEEEHHCCHHHHHHHHH
AMDGRIVQIGVIKGPAQSLDLFPMLAKRLTHIGSTLRSRTHEEKAVLIEDLEQSVFPHIR
HCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
RGAVKPVMYKTFDLGDARRAHELMDSGTHIGKIVLTTQAAHSAP
HCCCCCHHEEEECCCCHHHHHHHHHCCCCEEEEEEEECCCCCCC
>Mature Secondary Structure 
THATHTIPAAMVAIEITQPGGPDVLAPVQRPVPVPAADEVLIRIHAAGVNGPDVMQRRG
CCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHCC
LYDPPPGASDIPGLEVAGEIVSVGRDVIRFAVGDLVCALVPGGGYAEYAVAHESNTLTIP
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEEECCCEEECC
EGLSMVEAAALPETFLTVWLNLFQRGKFSAGESVLIHGGASGIGTTATMLAKAFGASKII
CCCHHHHHHHCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCEE
TTVGSDTQRDASIALGADVAVDYRNEDFVEAVARATDGRGVDVVVDIIAGDYVARNYAAA
EECCCCCCCCCEEEECCEEEEECCCHHHHHHHHHHCCCCCCEEEEEEHHCCHHHHHHHHH
AMDGRIVQIGVIKGPAQSLDLFPMLAKRLTHIGSTLRSRTHEEKAVLIEDLEQSVFPHIR
HCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
RGAVKPVMYKTFDLGDARRAHELMDSGTHIGKIVLTTQAAHSAP
HCCCCCHHEEEECCCCHHHHHHHHHCCCCEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]