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The map label for this gene is yafC [C]

Identifier: 94313188

GI number: 94313188

Start: 852292

End: 853344

Strand: Direct

Name: yafC [C]

Synonym: Rmet_4262

Alternate gene names: 94313188

Gene position: 852292-853344 (Clockwise)

Preceding gene: 94313184

Following gene: 94313191

Centisome position: 33.03

GC content: 63.34

Gene sequence:

>1053_bases
ATGCAGCAAATGGCCATCGCGGATTGCAACCCTTACAAGGCCACTAGCAGGCATGCCTATGGTGTGATCGGGGAGCAACA
GATGTCATTACGTACGGAAGAGATCGAGGCCTATCTGCGGGTCGTCGAGCTAGGGGGAATCAGCGCGGCAGCGCGGCATA
TGGGGTTATCCAAATCCGTTGTCAGCAAGCGCATCAGCGATCTGGAGCGGGAACTCGGCGCATCGTTGCTCCAGCGCTCT
TCGCGTCGCATGCAGCCCTCCGAGAGCGGCCGGTATTTCTATGAGCAGGCGCGCGCAGCCATGAGTCAGCTTACCCAAGC
CGCGCAGAGTGTCTCGGAGGCGGCGCAGGAAGTCTGTGGCGAACTGCGCATCCTGGCGCCCATGAGCTTTGGTACACGCT
GGTTGTCGCCGCTCATTGCGGAATTCGGCCGCGCCAACCCACGGCTGCGACTGAGTCTCGAACTGGACGACAGGTTGGTC
GATCTGGCCTACGGCGGGTACGACGTGGCCATCCGCATTACGCGGCTGCGCGACAGCGACCTCATCGCGCGCAAGCTTGC
GCCCAGTCGCCGCGTGGTGTGTTGCAGCCCGGACTATGCGGCGCGCGCCGGACTTCCCCGAACCGTCGAGGATATCGGCC
ACCATGCCTGCCTGTCATACAGCAATTCCTTGCCGGGCCAAATCTGGACCTTCCAGCCGGACGCGCATGAAGAAGCGCCG
AAGACCATCACGCCGCGCGGCATCTACACGGCCAACAACGGCGAGGTGCTGCGTGATGCCGTGCTTGCCGGCCATGGCTT
GGCCGTGTTGCCACGCTTCATCGTCTGGGAAGACCTGCGGGCGGGTCGGCTGATCGAGGTTCAGCCAGGGGCCACGCCGG
TGGAGGATGGCATCTTTGCCGTCTATCCCCGTAACGCATTCGGTTCGGCCAAGCTCAGGGCCCTCGTGCAGTTCCTGCAG
GCTTCGCTTTCGCAGCCGCCGTGGGAAGTTCCCGGCTCGTCGATGGAAAGCGCCGAAGTGGTACCCCTGTATGCGGAGGC
GCCCAAACGTTGA

Upstream 100 bases:

>100_bases
GTCTTGCATGGGCATGTCTGGTTGTTCAATTTATGGGACTCTGCCGATCATTTTTTATATCTACAGCCGGCGTCGTCCCA
ATACTAAGCTGTAGGCATCA

Downstream 100 bases:

>100_bases
AATTGGGCTCAGGCGCGCAAAGGGTAGGGCTTCTCCGGATCGATGCCGTACTTGGCGATGGCCTGGCTCAGTACGCCGCG
CTCCAGCGTGCCTTCATCCA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MQQMAIADCNPYKATSRHAYGVIGEQQMSLRTEEIEAYLRVVELGGISAAARHMGLSKSVVSKRISDLERELGASLLQRS
SRRMQPSESGRYFYEQARAAMSQLTQAAQSVSEAAQEVCGELRILAPMSFGTRWLSPLIAEFGRANPRLRLSLELDDRLV
DLAYGGYDVAIRITRLRDSDLIARKLAPSRRVVCCSPDYAARAGLPRTVEDIGHHACLSYSNSLPGQIWTFQPDAHEEAP
KTITPRGIYTANNGEVLRDAVLAGHGLAVLPRFIVWEDLRAGRLIEVQPGATPVEDGIFAVYPRNAFGSAKLRALVQFLQ
ASLSQPPWEVPGSSMESAEVVPLYAEAPKR

Sequences:

>Translated_350_residues
MQQMAIADCNPYKATSRHAYGVIGEQQMSLRTEEIEAYLRVVELGGISAAARHMGLSKSVVSKRISDLERELGASLLQRS
SRRMQPSESGRYFYEQARAAMSQLTQAAQSVSEAAQEVCGELRILAPMSFGTRWLSPLIAEFGRANPRLRLSLELDDRLV
DLAYGGYDVAIRITRLRDSDLIARKLAPSRRVVCCSPDYAARAGLPRTVEDIGHHACLSYSNSLPGQIWTFQPDAHEEAP
KTITPRGIYTANNGEVLRDAVLAGHGLAVLPRFIVWEDLRAGRLIEVQPGATPVEDGIFAVYPRNAFGSAKLRALVQFLQ
ASLSQPPWEVPGSSMESAEVVPLYAEAPKR
>Mature_350_residues
MQQMAIADCNPYKATSRHAYGVIGEQQMSLRTEEIEAYLRVVELGGISAAARHMGLSKSVVSKRISDLERELGASLLQRS
SRRMQPSESGRYFYEQARAAMSQLTQAAQSVSEAAQEVCGELRILAPMSFGTRWLSPLIAEFGRANPRLRLSLELDDRLV
DLAYGGYDVAIRITRLRDSDLIARKLAPSRRVVCCSPDYAARAGLPRTVEDIGHHACLSYSNSLPGQIWTFQPDAHEEAP
KTITPRGIYTANNGEVLRDAVLAGHGLAVLPRFIVWEDLRAGRLIEVQPGATPVEDGIFAVYPRNAFGSAKLRALVQFLQ
ASLSQPPWEVPGSSMESAEVVPLYAEAPKR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=301, Percent_Identity=31.8936877076412, Blast_Score=154, Evalue=7e-39,
Organism=Escherichia coli, GI87081978, Length=307, Percent_Identity=32.2475570032573, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI145693193, Length=295, Percent_Identity=32.8813559322034, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1789440, Length=294, Percent_Identity=29.9319727891156, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789639, Length=295, Percent_Identity=28.4745762711864, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1787128, Length=297, Percent_Identity=26.5993265993266, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787589, Length=281, Percent_Identity=25.9786476868327, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1788706, Length=165, Percent_Identity=31.5151515151515, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1789173, Length=275, Percent_Identity=26.9090909090909, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788481, Length=296, Percent_Identity=24.3243243243243, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1787601, Length=237, Percent_Identity=22.3628691983122, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790262, Length=244, Percent_Identity=25.4098360655738, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87082132, Length=265, Percent_Identity=26.0377358490566, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790783, Length=263, Percent_Identity=23.1939163498099, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 38507; Mature: 38507

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQMAIADCNPYKATSRHAYGVIGEQQMSLRTEEIEAYLRVVELGGISAAARHMGLSKSV
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHH
VSKRISDLERELGASLLQRSSRRMQPSESGRYFYEQARAAMSQLTQAAQSVSEAAQEVCG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELRILAPMSFGTRWLSPLIAEFGRANPRLRLSLELDDRLVDLAYGGYDVAIRITRLRDSD
CEEEEEECHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEEEEECCEEEEEEEEEECCCH
LIARKLAPSRRVVCCSPDYAARAGLPRTVEDIGHHACLSYSNSLPGQIWTFQPDAHEEAP
HHHHHCCCCCEEEEECCCHHHHCCCCHHHHHCCCHHHHHCCCCCCCCEEEECCCCCCCCC
KTITPRGIYTANNGEVLRDAVLAGHGLAVLPRFIVWEDLRAGRLIEVQPGATPVEDGIFA
CCCCCCCEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEE
VYPRNAFGSAKLRALVQFLQASLSQPPWEVPGSSMESAEVVPLYAEAPKR
EECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCC
>Mature Secondary Structure
MQQMAIADCNPYKATSRHAYGVIGEQQMSLRTEEIEAYLRVVELGGISAAARHMGLSKSV
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHH
VSKRISDLERELGASLLQRSSRRMQPSESGRYFYEQARAAMSQLTQAAQSVSEAAQEVCG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELRILAPMSFGTRWLSPLIAEFGRANPRLRLSLELDDRLVDLAYGGYDVAIRITRLRDSD
CEEEEEECHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEEEEECCEEEEEEEEEECCCH
LIARKLAPSRRVVCCSPDYAARAGLPRTVEDIGHHACLSYSNSLPGQIWTFQPDAHEEAP
HHHHHCCCCCEEEEECCCHHHHCCCCHHHHHCCCHHHHHCCCCCCCCEEEECCCCCCCCC
KTITPRGIYTANNGEVLRDAVLAGHGLAVLPRFIVWEDLRAGRLIEVQPGATPVEDGIFA
CCCCCCCEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEE
VYPRNAFGSAKLRALVQFLQASLSQPPWEVPGSSMESAEVVPLYAEAPKR
EECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]