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The map label for this gene is cmpR [H]

Identifier: 94313118

GI number: 94313118

Start: 774037

End: 774951

Strand: Reverse

Name: cmpR [H]

Synonym: Rmet_4191

Alternate gene names: 94313118

Gene position: 774951-774037 (Counterclockwise)

Preceding gene: 94313119

Following gene: 94313117

Centisome position: 30.04

GC content: 66.01

Gene sequence:

>915_bases
ATGCTTGGCGATCTGCTGATGACCTTCTACGAGGTGGCGCGACAAGGCAGCATCACCACCGCCGCTCGCCAGTTGCGAGT
CAGCCAGCCCACGGTCACCGGGCGCATCCGCCAGCTCGAGGAGCTCTACGGCGTGGAGTTGTTTCATCGGCGGGCCAGCC
GCGTGGACCTGAGCGATACCGGCGTCGCGCTGATGCCGCTGGCCGAACAGATCGTGCAGCAGGAGAGCAATGCCGACTTC
CTGCTGCGCAATGCCGGAAATCTCCGTATGGGCAACCTGCGGATCGGCGCAACCGGCCCCTATTACATCCTGCGCAGCGT
GGCGGCGTTCCGGCAGCGCTATCCGGCCATCGGCGTCAGCATCCAGATCGGCAACTCCCGGCAAATGCTCGATGCGCTTT
TCGAGTACCGCATCGATGCCGCCGTGTCGTCGCATGCGGTCAATGACGATCGCCTGCACCGAGTCAGGCTGGCAGCGGAC
CCGATGGTGCTGGTAACGCATCCCGCGCACCCGTTCGCACGCCGGCCGCGCGTTGAAGTTTCCGAACTCGCCGCCTGTCA
CCTGCTCGTGCGCGAACAGGGCTCGATGACGCGAGAGGCCACGGAAAGCGCGCTCCGTGCCGTCGGAGAGGAACTGCCGG
CGCACACTGTGATCGGTAGCCGCGAGGCCATCTGCGAGGCCATCCGCCACAACCTCGGCGCAAGCGTGATGCCGATGGGT
GAAGTGCCACGCGACCCGGCCTTGACGGTGGTGCCGTTCGCCAGCCGCGCACCGGTGATCCACGAATACCTGTATTGCCT
CAACAGCCGGCGCGAGACAAGGCTGCTCAGCGCGCTGCTGGACAGCCTGGTACTGCCTGGCGCCGCCTCCGGCCGCCATT
GCGAAGTGCCGCCGCCAGCGCCTATATTGAACTGA

Upstream 100 bases:

>100_bases
GCCAGCCCCCCGGCACCGGATTGGCTACGCACAAGCCTTCGTCACGCTGTCATATTTCCGCCTTATAGTCGGCAGCTCTC
CCGTTTCCGTTTGGAACCCC

Downstream 100 bases:

>100_bases
TCCGCCCGTCTTCCAAGCGCCCTCCGCCCCAAACGCCTCCCATCGATGACCGACACGGGCCGCTCCAGCTTTCCCGAGTA
CGACCAGCTACTCGCGCTGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MLGDLLMTFYEVARQGSITTAARQLRVSQPTVTGRIRQLEELYGVELFHRRASRVDLSDTGVALMPLAEQIVQQESNADF
LLRNAGNLRMGNLRIGATGPYYILRSVAAFRQRYPAIGVSIQIGNSRQMLDALFEYRIDAAVSSHAVNDDRLHRVRLAAD
PMVLVTHPAHPFARRPRVEVSELAACHLLVREQGSMTREATESALRAVGEELPAHTVIGSREAICEAIRHNLGASVMPMG
EVPRDPALTVVPFASRAPVIHEYLYCLNSRRETRLLSALLDSLVLPGAASGRHCEVPPPAPILN

Sequences:

>Translated_304_residues
MLGDLLMTFYEVARQGSITTAARQLRVSQPTVTGRIRQLEELYGVELFHRRASRVDLSDTGVALMPLAEQIVQQESNADF
LLRNAGNLRMGNLRIGATGPYYILRSVAAFRQRYPAIGVSIQIGNSRQMLDALFEYRIDAAVSSHAVNDDRLHRVRLAAD
PMVLVTHPAHPFARRPRVEVSELAACHLLVREQGSMTREATESALRAVGEELPAHTVIGSREAICEAIRHNLGASVMPMG
EVPRDPALTVVPFASRAPVIHEYLYCLNSRRETRLLSALLDSLVLPGAASGRHCEVPPPAPILN
>Mature_304_residues
MLGDLLMTFYEVARQGSITTAARQLRVSQPTVTGRIRQLEELYGVELFHRRASRVDLSDTGVALMPLAEQIVQQESNADF
LLRNAGNLRMGNLRIGATGPYYILRSVAAFRQRYPAIGVSIQIGNSRQMLDALFEYRIDAAVSSHAVNDDRLHRVRLAAD
PMVLVTHPAHPFARRPRVEVSELAACHLLVREQGSMTREATESALRAVGEELPAHTVIGSREAICEAIRHNLGASVMPMG
EVPRDPALTVVPFASRAPVIHEYLYCLNSRRETRLLSALLDSLVLPGAASGRHCEVPPPAPILN

Specific function: Activates transcription of the cmpABCD operon under carbon dioxide-limited conditions. Specifically binds to the cmpR- cmpA intergenic region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788481, Length=235, Percent_Identity=30.6382978723404, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI157672245, Length=259, Percent_Identity=29.3436293436293, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI145693105, Length=272, Percent_Identity=25.7352941176471, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790399, Length=251, Percent_Identity=26.2948207171315, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI87082132, Length=270, Percent_Identity=28.1481481481481, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787806, Length=290, Percent_Identity=25.5172413793103, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787601, Length=170, Percent_Identity=30, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787879, Length=183, Percent_Identity=26.775956284153, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788296, Length=224, Percent_Identity=27.6785714285714, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33480; Mature: 33480

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGDLLMTFYEVARQGSITTAARQLRVSQPTVTGRIRQLEELYGVELFHRRASRVDLSDT
CHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GVALMPLAEQIVQQESNADFLLRNAGNLRMGNLRIGATGPYYILRSVAAFRQRYPAIGVS
CCHHHHHHHHHHHCCCCCCEEEECCCCEEECCEEECCCCHHHHHHHHHHHHHHCCCCEEE
IQIGNSRQMLDALFEYRIDAAVSSHAVNDDRLHRVRLAADPMVLVTHPAHPFARRPRVEV
EEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHEEEEECCCEEEEECCCCCHHCCCCCCH
SELAACHLLVREQGSMTREATESALRAVGEELPAHTVIGSREAICEAIRHNLGASVMPMG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHCCCCCCCCC
EVPRDPALTVVPFASRAPVIHEYLYCLNSRRETRLLSALLDSLVLPGAASGRHCEVPPPA
CCCCCCCEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PILN
CCCC
>Mature Secondary Structure
MLGDLLMTFYEVARQGSITTAARQLRVSQPTVTGRIRQLEELYGVELFHRRASRVDLSDT
CHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GVALMPLAEQIVQQESNADFLLRNAGNLRMGNLRIGATGPYYILRSVAAFRQRYPAIGVS
CCHHHHHHHHHHHCCCCCCEEEECCCCEEECCEEECCCCHHHHHHHHHHHHHHCCCCEEE
IQIGNSRQMLDALFEYRIDAAVSSHAVNDDRLHRVRLAADPMVLVTHPAHPFARRPRVEV
EEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHEEEEECCCEEEEECCCCCHHCCCCCCH
SELAACHLLVREQGSMTREATESALRAVGEELPAHTVIGSREAICEAIRHNLGASVMPMG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHCCCCCCCCC
EVPRDPALTVVPFASRAPVIHEYLYCLNSRRETRLLSALLDSLVLPGAASGRHCEVPPPA
CCCCCCCEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PILN
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]