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The map label for this gene is cheD [H]

Identifier: 94313112

GI number: 94313112

Start: 768370

End: 769443

Strand: Direct

Name: cheD [H]

Synonym: Rmet_4185

Alternate gene names: 94313112

Gene position: 768370-769443 (Clockwise)

Preceding gene: 291481517

Following gene: 94313114

Centisome position: 29.78

GC content: 65.64

Gene sequence:

>1074_bases
ATGCGCATCCGGCTGGGCGCGGCATTTGGGGTGGTGGTGGTGCTGGTGGCCGTCATGATGACGCTGGCGTTGGGCCAGAT
CACCGATGAGGGCACGCGAGGCTGGCTCTATGGGCTGGGCACGGCTGTGGCGGTGTTCAGCGTAGTGTGCTGGGCCCGTC
TGGCCAGTGCGATCGAGGCGCCGCTCAAGGAGGCCGAATTCATCGCGGAGACGGTGGCTGCCGGCGATCTGAGCAAGGAT
TTCGAAACCGCGCGCGGTGGCGATTTCGGTCGTCTGCTCGGCGGCCTGGGAGAGATGGAAGACATGCTGACCGACCTGGT
TACGCGCATCAAGTCCGCCAGCGATTCGATTTCTTCGGCATCGCAGCAAATCGCCGTGGGCAACACCGATCTGTCGCAGC
GGACCGAGGAGCAGGCGGCCACGCTGCAGGAAACCGCGTCGAGCATGGGCGAACTGACTGCGATGGTCCGGCAGAACACC
GAACGCGCGCGCACCGCCAACGGGCTTGCGGCTTCGGCGTCCGGCATCGCCGAGCGCGGTGGCGCGATCGTCGGCAATGT
CGTGGAAACGATGGATGCCATCAGCGTCAGTTCGCGCAAGGTGACTGACATCATCGCCGTCATCGAGGGCATCGCATTCC
AGACCAATATCCTGGCCCTGAATGCCGCCGTGGAAGCGGCGCGCGCGGGCGAGCAGGGTCGCGGTTTCGCCGTGGTGGCC
GGCGAGGTGCGTACGCTGGCCCAGCGCAGTGCTGCGGCTGCCAAGGAGATCAACGTGCTGATCAACGACTCGGCGCGTCA
GGTGGAAAGCGGTTCGGCGCTGGTCGGCCAGGCCGGGCAGACCATGGAGGAAATTGTCCAGGCGGTGCGTCGCGTGACGC
AGATCCTTGGCGAGATCGCGACGGCTTCCGAGCACCAGAGCGACGGCATCGAGCAGGTGAACGTAGCGGTGACCCAGATG
GACGATGTGACGCAGCAGAACGCCGCATTGGTCGAACAGGCGGCTGCGGCTTCGTCGGCGCTGGCCGAGCAGGCGCAGGA
GCTTCAGAAAGTGGTGGGCGAGTTCAAGCTGTAG

Upstream 100 bases:

>100_bases
GGTAAAGGTTGCTTGGCTGGCTCCGTTAGTCCATCGATAGCCCCGGACAACGCGGGGCACGAAAGAGGAGCGGATAAAGA
TGGCGTGGGATAACTTGAGC

Downstream 100 bases:

>100_bases
CCTGTCGCTTATCGCCGTCAGAGCTTCCCGCTCTTCAGGTAGGCGATCACTGGCGCCCAGAAACGGGTCATGTAGGAGGG
CTCGATCGCCGCGTCATGCG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MRIRLGAAFGVVVVLVAVMMTLALGQITDEGTRGWLYGLGTAVAVFSVVCWARLASAIEAPLKEAEFIAETVAAGDLSKD
FETARGGDFGRLLGGLGEMEDMLTDLVTRIKSASDSISSASQQIAVGNTDLSQRTEEQAATLQETASSMGELTAMVRQNT
ERARTANGLAASASGIAERGGAIVGNVVETMDAISVSSRKVTDIIAVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVA
GEVRTLAQRSAAAAKEINVLINDSARQVESGSALVGQAGQTMEEIVQAVRRVTQILGEIATASEHQSDGIEQVNVAVTQM
DDVTQQNAALVEQAAAASSALAEQAQELQKVVGEFKL

Sequences:

>Translated_357_residues
MRIRLGAAFGVVVVLVAVMMTLALGQITDEGTRGWLYGLGTAVAVFSVVCWARLASAIEAPLKEAEFIAETVAAGDLSKD
FETARGGDFGRLLGGLGEMEDMLTDLVTRIKSASDSISSASQQIAVGNTDLSQRTEEQAATLQETASSMGELTAMVRQNT
ERARTANGLAASASGIAERGGAIVGNVVETMDAISVSSRKVTDIIAVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVA
GEVRTLAQRSAAAAKEINVLINDSARQVESGSALVGQAGQTMEEIVQAVRRVTQILGEIATASEHQSDGIEQVNVAVTQM
DDVTQQNAALVEQAAAASSALAEQAQELQKVVGEFKL
>Mature_357_residues
MRIRLGAAFGVVVVLVAVMMTLALGQITDEGTRGWLYGLGTAVAVFSVVCWARLASAIEAPLKEAEFIAETVAAGDLSKD
FETARGGDFGRLLGGLGEMEDMLTDLVTRIKSASDSISSASQQIAVGNTDLSQRTEEQAATLQETASSMGELTAMVRQNT
ERARTANGLAASASGIAERGGAIVGNVVETMDAISVSSRKVTDIIAVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVA
GEVRTLAQRSAAAAKEINVLINDSARQVESGSALVGQAGQTMEEIVQAVRRVTQILGEIATASEHQSDGIEQVNVAVTQM
DDVTQQNAALVEQAAAASSALAEQAQELQKVVGEFKL

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=309, Percent_Identity=55.663430420712, Blast_Score=289, Evalue=2e-79,
Organism=Escherichia coli, GI2367378, Length=295, Percent_Identity=55.2542372881356, Blast_Score=287, Evalue=6e-79,
Organism=Escherichia coli, GI1787690, Length=337, Percent_Identity=50.1483679525223, Blast_Score=276, Evalue=1e-75,
Organism=Escherichia coli, GI1788194, Length=316, Percent_Identity=50.6329113924051, Blast_Score=265, Evalue=3e-72,
Organism=Escherichia coli, GI1789453, Length=352, Percent_Identity=36.9318181818182, Blast_Score=209, Evalue=3e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 37080; Mature: 37080

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIRLGAAFGVVVVLVAVMMTLALGQITDEGTRGWLYGLGTAVAVFSVVCWARLASAIEA
CEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLKEAEFIAETVAAGDLSKDFETARGGDFGRLLGGLGEMEDMLTDLVTRIKSASDSISSA
HHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
SQQIAVGNTDLSQRTEEQAATLQETASSMGELTAMVRQNTERARTANGLAASASGIAERG
HHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
GAIVGNVVETMDAISVSSRKVTDIIAVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVA
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEH
GEVRTLAQRSAAAAKEINVLINDSARQVESGSALVGQAGQTMEEIVQAVRRVTQILGEIA
HHHHHHHHHHHHHHHHHHHEECCCHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHH
TASEHQSDGIEQVNVAVTQMDDVTQQNAALVEQAAAASSALAEQAQELQKVVGEFKL
HHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRIRLGAAFGVVVVLVAVMMTLALGQITDEGTRGWLYGLGTAVAVFSVVCWARLASAIEA
CEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLKEAEFIAETVAAGDLSKDFETARGGDFGRLLGGLGEMEDMLTDLVTRIKSASDSISSA
HHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
SQQIAVGNTDLSQRTEEQAATLQETASSMGELTAMVRQNTERARTANGLAASASGIAERG
HHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
GAIVGNVVETMDAISVSSRKVTDIIAVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVA
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEH
GEVRTLAQRSAAAAKEINVLINDSARQVESGSALVGQAGQTMEEIVQAVRRVTQILGEIA
HHHHHHHHHHHHHHHHHHHEECCCHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHH
TASEHQSDGIEQVNVAVTQMDDVTQQNAALVEQAAAASSALAEQAQELQKVVGEFKL
HHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]