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The map label for this gene is dhaR [H]

Identifier: 94313029

GI number: 94313029

Start: 670596

End: 671231

Strand: Direct

Name: dhaR [H]

Synonym: Rmet_4102

Alternate gene names: 94313029

Gene position: 670596-671231 (Clockwise)

Preceding gene: 94313028

Following gene: 94313030

Centisome position: 25.99

GC content: 62.89

Gene sequence:

>636_bases
ATGGCTCGTACTTCAGACAAGACCGACATTCCGAACCGCCTGACCAAGGCGGGTCGCGAACTGTTCTCCCACCACGGCTA
CAACGCCACCGGCATCCAGCAGATCACCGATCACGCTGGCGTGCCGAAGGGCTCGTTTTACAACCACTTCGAAAGCAAGG
AAGCGTTCGCGGCAGCGATCATCGCGGAATACGCCGATTATCTGCACCGGTCATGGGAAGCCATGATGGAGGACGCCCCG
CCCGAGCCGATGGCGGCGATCCGCTATGTCTTCACGCGGATGATTGCCTATCACGAATGCTGTCCCACGCAGGCGGGTTG
CCTGATCGGCAACTTCGCTGCCGAGATCGCCTTGACGAGCGATACCTGTCGGGCCGTGCTGCAGGACGCCCAGTTCGCCT
GGCGCGAACGGCTGGCCGGCATGATCAGCCTCGCCCAGGCGCATGGTGAAATCCGTGCCGATATCGCGTCAGCCGAGCTC
TCGGGGCTCGTCTGGGATACGTGGGAGGGCGCCTTGCTACGTATGAAGATTGAACGCTCGGTTGCCCCGCTGCGCCGCAG
CGTCGACCTGATGTTCGACCACCTGTTCCAGCCGGCCGCCGCGGCCGGCATCCACCACAGTCCAACCTTGGAGTAA

Upstream 100 bases:

>100_bases
GGCTGGGCGGAGCGGGGCCGCCAGGCCCATGGCCAATGGCGGAAATAGTGACGATTCAGGCGTTTGACTTTTTAAGACGA
CTGGTCATATTATTTCCGCC

Downstream 100 bases:

>100_bases
GTCATTCATGGGTGCACAGACCGAAGCATTCCTCACCGAAGCCCTGTTTCAGCCGATCAAGCTGGGCCGTATCGAACTCG
CCAACCGCATGGCCATGGCA

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MARTSDKTDIPNRLTKAGRELFSHHGYNATGIQQITDHAGVPKGSFYNHFESKEAFAAAIIAEYADYLHRSWEAMMEDAP
PEPMAAIRYVFTRMIAYHECCPTQAGCLIGNFAAEIALTSDTCRAVLQDAQFAWRERLAGMISLAQAHGEIRADIASAEL
SGLVWDTWEGALLRMKIERSVAPLRRSVDLMFDHLFQPAAAAGIHHSPTLE

Sequences:

>Translated_211_residues
MARTSDKTDIPNRLTKAGRELFSHHGYNATGIQQITDHAGVPKGSFYNHFESKEAFAAAIIAEYADYLHRSWEAMMEDAP
PEPMAAIRYVFTRMIAYHECCPTQAGCLIGNFAAEIALTSDTCRAVLQDAQFAWRERLAGMISLAQAHGEIRADIASAEL
SGLVWDTWEGALLRMKIERSVAPLRRSVDLMFDHLFQPAAAAGIHHSPTLE
>Mature_210_residues
ARTSDKTDIPNRLTKAGRELFSHHGYNATGIQQITDHAGVPKGSFYNHFESKEAFAAAIIAEYADYLHRSWEAMMEDAPP
EPMAAIRYVFTRMIAYHECCPTQAGCLIGNFAAEIALTSDTCRAVLQDAQFAWRERLAGMISLAQAHGEIRADIASAELS
GLVWDTWEGALLRMKIERSVAPLRRSVDLMFDHLFQPAAAAGIHHSPTLE

Specific function: Transcriptional repressor for the dhaA haloalkane dehalogenase gene [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693141, Length=192, Percent_Identity=22.9166666666667, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 23406; Mature: 23275

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARTSDKTDIPNRLTKAGRELFSHHGYNATGIQQITDHAGVPKGSFYNHFESKEAFAAAI
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
IAEYADYLHRSWEAMMEDAPPEPMAAIRYVFTRMIAYHECCPTQAGCLIGNFAAEIALTS
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCH
DTCRAVLQDAQFAWRERLAGMISLAQAHGEIRADIASAELSGLVWDTWEGALLRMKIERS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
VAPLRRSVDLMFDHLFQPAAAAGIHHSPTLE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ARTSDKTDIPNRLTKAGRELFSHHGYNATGIQQITDHAGVPKGSFYNHFESKEAFAAAI
CCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
IAEYADYLHRSWEAMMEDAPPEPMAAIRYVFTRMIAYHECCPTQAGCLIGNFAAEIALTS
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCH
DTCRAVLQDAQFAWRERLAGMISLAQAHGEIRADIASAELSGLVWDTWEGALLRMKIERS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
VAPLRRSVDLMFDHLFQPAAAAGIHHSPTLE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10735862 [H]