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The map label for this gene is qoxC [H]

Identifier: 94312886

GI number: 94312886

Start: 518096

End: 518800

Strand: Direct

Name: qoxC [H]

Synonym: Rmet_3958

Alternate gene names: 94312886

Gene position: 518096-518800 (Clockwise)

Preceding gene: 94312885

Following gene: 94312887

Centisome position: 20.08

GC content: 61.28

Gene sequence:

>705_bases
ATGCATTCGCAAGTTCCTTCTTCGGCAGGATCGCATCCGGAAGCCTGGAATCCGCCGGGCGGCTTCAGGGGCCTCGTCGC
TGACTGGTCATCCGACCAGCGCGCATTCAAGGTGTCCTGGGGCAAGGCGATGATGTGGATCTTCCTGCTTTCCGACACCT
TCATCTTCAGTTGCTTCCTGATCGGCTATATGACTGTGCGCATCTCCACCACGGTGCCATGGCCGGATACCAGCAAGGCT
TTCGCCGAGAACATCGGCGGTCATACGCTACCGCTGATCCTGATCGCAATCATGACCTTCGTGCTGATCACCAGCAGTGG
CACGATGGCGATGGCCGTGAATTTCGCCTACCGTCGCGAGCGGCGCCCCTGCGGCCTGCTGATGCTGGCGACCGCCGCGC
TCGGGGCAACGTTCGTCGGTCTGCAGGCGTTCGAATGGACCACACTGATCGTGCACGAGGGTGTGCGGCCCTGGGGCAAT
CCAATGGGCGCCGCGCAGTTCGGCTCCACGTTCTTCATGATCACCGGCTTCCACGGCTTTCACGTGACCTGCGGCGTGAT
CTACCTGCTGACGATCGCCAGCAAGGTCGTGCGCGGGCACTACGAACCAGGCGGCAACTACCAGGTCGTGGAGATCGCCG
GCCTCTACTGGCACTTCGTCGATCTGGTCTGGGTCTTCATCTTCGCGCTGTTCTATCTCTGGTGA

Upstream 100 bases:

>100_bases
CTTCCTGTTGGCGGTATGGGTCGTGTTGCTCGGCGCGCTGGGCTGGCTCACGCCGGAGCTCGTCGCGTACATCTGTGGCA
GGTCTTGACGGAGAGCGCCC

Downstream 100 bases:

>100_bases
GGGCGACCATGGCATCGACACCCATCACTCCGGCCCCCGAGGCGGCCCACGGTGGTCACGGCAAACAGGAACATCCTATC
GGCCTCTATCTGAAGGTCTG

Product: cytochrome c oxidase subunit III

Products: ferricytochrome c; H2O

Alternate protein names: Quinol oxidase polypeptide III [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MHSQVPSSAGSHPEAWNPPGGFRGLVADWSSDQRAFKVSWGKAMMWIFLLSDTFIFSCFLIGYMTVRISTTVPWPDTSKA
FAENIGGHTLPLILIAIMTFVLITSSGTMAMAVNFAYRRERRPCGLLMLATAALGATFVGLQAFEWTTLIVHEGVRPWGN
PMGAAQFGSTFFMITGFHGFHVTCGVIYLLTIASKVVRGHYEPGGNYQVVEIAGLYWHFVDLVWVFIFALFYLW

Sequences:

>Translated_234_residues
MHSQVPSSAGSHPEAWNPPGGFRGLVADWSSDQRAFKVSWGKAMMWIFLLSDTFIFSCFLIGYMTVRISTTVPWPDTSKA
FAENIGGHTLPLILIAIMTFVLITSSGTMAMAVNFAYRRERRPCGLLMLATAALGATFVGLQAFEWTTLIVHEGVRPWGN
PMGAAQFGSTFFMITGFHGFHVTCGVIYLLTIASKVVRGHYEPGGNYQVVEIAGLYWHFVDLVWVFIFALFYLW
>Mature_234_residues
MHSQVPSSAGSHPEAWNPPGGFRGLVADWSSDQRAFKVSWGKAMMWIFLLSDTFIFSCFLIGYMTVRISTTVPWPDTSKA
FAENIGGHTLPLILIAIMTFVLITSSGTMAMAVNFAYRRERRPCGLLMLATAALGATFVGLQAFEWTTLIVHEGVRPWGN
PMGAAQFGSTFFMITGFHGFHVTCGVIYLLTIASKVVRGHYEPGGNYQVVEIAGLYWHFVDLVWVFIFALFYLW

Specific function: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water [H]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831113, Length=169, Percent_Identity=30.1775147928994, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1786633, Length=190, Percent_Identity=31.0526315789474, Blast_Score=81, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014246
- InterPro:   IPR000298
- InterPro:   IPR013833 [H]

Pfam domain/function: PF00510 COX3 [H]

EC number: 1.9.3.1

Molecular weight: Translated: 26036; Mature: 26036

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSQVPSSAGSHPEAWNPPGGFRGLVADWSSDQRAFKVSWGKAMMWIFLLSDTFIFSCFL
CCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHH
IGYMTVRISTTVPWPDTSKAFAENIGGHTLPLILIAIMTFVLITSSGTMAMAVNFAYRRE
HHHHEEEEEEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHC
RRPCGLLMLATAALGATFVGLQAFEWTTLIVHEGVRPWGNPMGAAQFGSTFFMITGFHGF
CCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCHHHHCCEEEEEECCCCH
HVTCGVIYLLTIASKVVRGHYEPGGNYQVVEIAGLYWHFVDLVWVFIFALFYLW
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MHSQVPSSAGSHPEAWNPPGGFRGLVADWSSDQRAFKVSWGKAMMWIFLLSDTFIFSCFL
CCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHH
IGYMTVRISTTVPWPDTSKAFAENIGGHTLPLILIAIMTFVLITSSGTMAMAVNFAYRRE
HHHHEEEEEEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHC
RRPCGLLMLATAALGATFVGLQAFEWTTLIVHEGVRPWGNPMGAAQFGSTFFMITGFHGF
CCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCHHHHCCEEEEEECCCCH
HVTCGVIYLLTIASKVVRGHYEPGGNYQVVEIAGLYWHFVDLVWVFIFALFYLW
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ferrocytochrome c; O2

Specific reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA