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The map label for this gene is arcB [H]

Identifier: 94312854

GI number: 94312854

Start: 485101

End: 486009

Strand: Reverse

Name: arcB [H]

Synonym: Rmet_3926

Alternate gene names: 94312854

Gene position: 486009-485101 (Counterclockwise)

Preceding gene: 94312855

Following gene: 291481498

Centisome position: 18.84

GC content: 65.46

Gene sequence:

>909_bases
ATGAAGCCTGTCACCCTGATTGGCGCGCCGACCGACGTGGGCGCCAGCATCCGTGGCGCCTCGATGGGCCCCGAAGCCTT
GCGCGTGGCGGACATCGCCGGCGCCCTGGTGCGCAACGGCCTCGATGTCACCGATCTGGGCAACCTCGTGGGCCCTGGCA
ACCCTAACCTGCCACCCACGGATGGCGTTCGGCACCTGCCGGAGGTTGTCGCCTGGAACCGTCTGGTCATGGACGCCACA
TACCAGGCCCTGGCCACCGGCCAGTTGCCGCTGCTGATGGGTGGCGACCACTGCCTGGCGATTGGCTCGGTCAATGCCGC
GGCTCGCTATTGCCGCGAGCAGGGAAAGAAGCTCTTGGTGCTCTGGCTTGATGCGCACGCCGATGCCAACACCGGCAGCA
CCAGCCCGACCGGGAACACCCATGGCATGCCGGTGGCGTGCCTGTGCGGGGATGGTCCCGCCCCGCTTGTGTCACTAGGC
GGCGTGACGCCCGCCACCTCACCCCGGAACATTCGGCAGATCGGCATCCGCAGTGTCGATGCCGAGGAGAAAAAGCGGCT
GCGTGAGTTGGGCCTGACCGTCTACGACATGCGCTACATCGACGAGAACGGCATGAGGGCCACAATGGAGCAGGCGTTGG
CGGGCATCGATGGCGATACCCATCTGCATGTCAGCTTCGACGTGGATTTCCTCGACAGCCAGATTGCGCCGGGCGTCGGC
ACGGCGGTTCGCGGTGGCCCTACCTATCGAGAAGCGCATCTCGCACTGGAAATGATCGAAGACACCGGCGCCCTGGGCTC
CATCGACGTGGTCGAACTGAACCCAGCGCGCGACGTCCACAACCAGACCGCCGAGCTGGTCGTCGAATTACTGGAGAGCC
TGTTCGGGAAATCGACGCTGCTGCGTTGA

Upstream 100 bases:

>100_bases
TGAGACCTCGCCGACATCTCGCCAGCATCTCGCTGACGTTCGACACCCGTTCGTGCCATGATGGCAGGCATCTATCGTCC
CCACTGAACCTGGAGACCCC

Downstream 100 bases:

>100_bases
TGGCGCGAGCCCCGCTGGCTGGCGGCAGGCAATAAAAAAGGAGGCAGTCACAGACTGCCTCCTTTCGATGCCGGTGCTCC
AGTCGACTACGGCCTACGAA

Product: arginase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MKPVTLIGAPTDVGASIRGASMGPEALRVADIAGALVRNGLDVTDLGNLVGPGNPNLPPTDGVRHLPEVVAWNRLVMDAT
YQALATGQLPLLMGGDHCLAIGSVNAAARYCREQGKKLLVLWLDAHADANTGSTSPTGNTHGMPVACLCGDGPAPLVSLG
GVTPATSPRNIRQIGIRSVDAEEKKRLRELGLTVYDMRYIDENGMRATMEQALAGIDGDTHLHVSFDVDFLDSQIAPGVG
TAVRGGPTYREAHLALEMIEDTGALGSIDVVELNPARDVHNQTAELVVELLESLFGKSTLLR

Sequences:

>Translated_302_residues
MKPVTLIGAPTDVGASIRGASMGPEALRVADIAGALVRNGLDVTDLGNLVGPGNPNLPPTDGVRHLPEVVAWNRLVMDAT
YQALATGQLPLLMGGDHCLAIGSVNAAARYCREQGKKLLVLWLDAHADANTGSTSPTGNTHGMPVACLCGDGPAPLVSLG
GVTPATSPRNIRQIGIRSVDAEEKKRLRELGLTVYDMRYIDENGMRATMEQALAGIDGDTHLHVSFDVDFLDSQIAPGVG
TAVRGGPTYREAHLALEMIEDTGALGSIDVVELNPARDVHNQTAELVVELLESLFGKSTLLR
>Mature_302_residues
MKPVTLIGAPTDVGASIRGASMGPEALRVADIAGALVRNGLDVTDLGNLVGPGNPNLPPTDGVRHLPEVVAWNRLVMDAT
YQALATGQLPLLMGGDHCLAIGSVNAAARYCREQGKKLLVLWLDAHADANTGSTSPTGNTHGMPVACLCGDGPAPLVSLG
GVTPATSPRNIRQIGIRSVDAEEKKRLRELGLTVYDMRYIDENGMRATMEQALAGIDGDTHLHVSFDVDFLDSQIAPGVG
TAVRGGPTYREAHLALEMIEDTGALGSIDVVELNPARDVHNQTAELVVELLESLFGKSTLLR

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI4502215, Length=305, Percent_Identity=34.7540983606557, Blast_Score=162, Evalue=3e-40,
Organism=Homo sapiens, GI10947139, Length=278, Percent_Identity=37.0503597122302, Blast_Score=159, Evalue=4e-39,
Organism=Escherichia coli, GI1789306, Length=278, Percent_Identity=28.4172661870504, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71996843, Length=224, Percent_Identity=34.8214285714286, Blast_Score=114, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6325146, Length=215, Percent_Identity=39.0697674418605, Blast_Score=149, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24638886, Length=305, Percent_Identity=34.4262295081967, Blast_Score=154, Evalue=8e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.1 [H]

Molecular weight: Translated: 31778; Mature: 31778

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPVTLIGAPTDVGASIRGASMGPEALRVADIAGALVRNGLDVTDLGNLVGPGNPNLPPT
CCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCC
DGVRHLPEVVAWNRLVMDATYQALATGQLPLLMGGDHCLAIGSVNAAARYCREQGKKLLV
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCHHHHHHHHHHCCCEEEE
LWLDAHADANTGSTSPTGNTHGMPVACLCGDGPAPLVSLGGVTPATSPRNIRQIGIRSVD
EEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEECCCCCCCCCCHHHHHCCCCCC
AEEKKRLRELGLTVYDMRYIDENGMRATMEQALAGIDGDTHLHVSFDVDFLDSQIAPGVG
HHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEEEHHHHHHCCCCCCC
TAVRGGPTYREAHLALEMIEDTGALGSIDVVELNPARDVHNQTAELVVELLESLFGKSTL
CCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCHHHC
LR
CC
>Mature Secondary Structure
MKPVTLIGAPTDVGASIRGASMGPEALRVADIAGALVRNGLDVTDLGNLVGPGNPNLPPT
CCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCC
DGVRHLPEVVAWNRLVMDATYQALATGQLPLLMGGDHCLAIGSVNAAARYCREQGKKLLV
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCHHHHHHHHHHCCCEEEE
LWLDAHADANTGSTSPTGNTHGMPVACLCGDGPAPLVSLGGVTPATSPRNIRQIGIRSVD
EEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEECCCCCCCCCCHHHHHCCCCCC
AEEKKRLRELGLTVYDMRYIDENGMRATMEQALAGIDGDTHLHVSFDVDFLDSQIAPGVG
HHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEEEHHHHHHCCCCCCC
TAVRGGPTYREAHLALEMIEDTGALGSIDVVELNPARDVHNQTAELVVELLESLFGKSTL
CCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCHHHC
LR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9375792 [H]