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The map label for this gene is gudP [H]

Identifier: 94312816

GI number: 94312816

Start: 432256

End: 433557

Strand: Reverse

Name: gudP [H]

Synonym: Rmet_3888

Alternate gene names: 94312816

Gene position: 433557-432256 (Counterclockwise)

Preceding gene: 94312819

Following gene: 94312815

Centisome position: 16.8

GC content: 64.36

Gene sequence:

>1302_bases
ATGCAATCCACAAGCCCCGCCGCGGCCTCGCTCGCGGTTCCCCGCAGCAGCGTGCGATGGAAGATCTTCCTGATGATGCT
GCTCCTCGTGGCGATCAACTACATCGACCGCGCATCGCTGTCGGTGGCCATGCCCCTGATCGCGAAGGAATTCGACCTGA
GTCCCGCCATGCAGGGGCTGATCCTGAGTTCGTTCTTCTGGACCTATGCCGTCATGCAGGTGCCGGGCGGCATGCTGGCC
GACAAGTACAAGCCGCGCATCGTGATCGCTACGGCTACCGTGTTCTGGGGTGCATTCCAGGCGCTGGCGGCGGTCTGCAC
CAATGCCACCTCGCTGCTGCTGACGCGGCTGGGGCTCGGCGCTGCGGAAGCGCCGATCTACCCGGCCGGCGGCAAGCTCA
ATGCCATCTGGATGACGAAGAACGAACGTGGCCGTGGCGCCACGCTGCTCGACGGCGGCGCGCCGCTGGGCGCGGCACTT
GGCTCGCTCATCATTGCCGGGCTGATCAGCGAACTGGGCTCGTGGCGCCTGTCGTTCGTCGTGGCCGGCGTTGGCACGGT
GCTGGCCGGCTTCGTGGCATGGTGGTACATCCGCAACTCGCCGCGCGAACACCTGGGCGTGAATGAACAGGAAGCCCGTC
ATATCGAGGACGCGCTTGCCCTGGAGCACAGCGAGGAGCCGACCAACCTGAGCGGCCGTTCACTGGACTTCTTCAAGTAC
CGCTCGGTCTGGTGCATGGCCATCAGCTGGATGTGCTTCAACGCCGTGTTCTACGGCTTGCTAACCTGGATGCCCACCTA
CCTGAGCAAGGCCCGCGGCTTCGACCTGAAGCAGATGGGCGGCGCGAGCTTCATCATCTTTTTTGCCGGATTCGTCGGCG
AACTGATCGGCGGCTGGATCGCCGACAAGTGGAAGGAAGCCGGCGGACGCCCGAACGTGGTGATGCGCACACTGTTCGGC
ATCGCCGCGGTGGTGGCTACGGTGTCGATCTTCTCGGTCGCCTACGTCACCGACCCCGTAGCGGTCGTGGTACTGCTGTC
CTCCACCCTGTTCTTCCTGCGCTGGTGCGGCCTGTTCTGGTCCGTGCCGTCGATGCTGGGCACCCGCAACAAGGTGGGCT
TCCTCGGCGGCGTGATGAACCTGGGCGGCAACATCGCCGGCATCAGCGTGCCAATCATCGTCGGCCTGATCGTCCAGGCC
ACCGGCTCGTACTTCCTGGCGCTGATGTTCTTTGCCGCCTGCGGCATCGGCCTGCTGCTGGCGTCGACCAACATCGACTA
CGAAAAGAAGATTCCGGTCTGA

Upstream 100 bases:

>100_bases
TGTTGTAATTACAGATTACGTATCCTATACTGCGTCCAGTTGCGCGACACGCTAAACCAAACGCCTCACCGAAGGCATCA
AGGACAAGGAGACACCCGTC

Downstream 100 bases:

>100_bases
CGGTACCGCCGCAGCGCTGGAACCCCGCATTCCCACACACACAGAGGCGCCGCCCTGCGGACGGCGCCCGTTTGAACTCC
TGAGTAATACCCATCATGAC

Product: major facilitator superfamily transporter

Products: NA

Alternate protein names: D-glucarate permease [H]

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MQSTSPAAASLAVPRSSVRWKIFLMMLLLVAINYIDRASLSVAMPLIAKEFDLSPAMQGLILSSFFWTYAVMQVPGGMLA
DKYKPRIVIATATVFWGAFQALAAVCTNATSLLLTRLGLGAAEAPIYPAGGKLNAIWMTKNERGRGATLLDGGAPLGAAL
GSLIIAGLISELGSWRLSFVVAGVGTVLAGFVAWWYIRNSPREHLGVNEQEARHIEDALALEHSEEPTNLSGRSLDFFKY
RSVWCMAISWMCFNAVFYGLLTWMPTYLSKARGFDLKQMGGASFIIFFAGFVGELIGGWIADKWKEAGGRPNVVMRTLFG
IAAVVATVSIFSVAYVTDPVAVVVLLSSTLFFLRWCGLFWSVPSMLGTRNKVGFLGGVMNLGGNIAGISVPIIVGLIVQA
TGSYFLALMFFAACGIGLLLASTNIDYEKKIPV

Sequences:

>Translated_433_residues
MQSTSPAAASLAVPRSSVRWKIFLMMLLLVAINYIDRASLSVAMPLIAKEFDLSPAMQGLILSSFFWTYAVMQVPGGMLA
DKYKPRIVIATATVFWGAFQALAAVCTNATSLLLTRLGLGAAEAPIYPAGGKLNAIWMTKNERGRGATLLDGGAPLGAAL
GSLIIAGLISELGSWRLSFVVAGVGTVLAGFVAWWYIRNSPREHLGVNEQEARHIEDALALEHSEEPTNLSGRSLDFFKY
RSVWCMAISWMCFNAVFYGLLTWMPTYLSKARGFDLKQMGGASFIIFFAGFVGELIGGWIADKWKEAGGRPNVVMRTLFG
IAAVVATVSIFSVAYVTDPVAVVVLLSSTLFFLRWCGLFWSVPSMLGTRNKVGFLGGVMNLGGNIAGISVPIIVGLIVQA
TGSYFLALMFFAACGIGLLLASTNIDYEKKIPV
>Mature_433_residues
MQSTSPAAASLAVPRSSVRWKIFLMMLLLVAINYIDRASLSVAMPLIAKEFDLSPAMQGLILSSFFWTYAVMQVPGGMLA
DKYKPRIVIATATVFWGAFQALAAVCTNATSLLLTRLGLGAAEAPIYPAGGKLNAIWMTKNERGRGATLLDGGAPLGAAL
GSLIIAGLISELGSWRLSFVVAGVGTVLAGFVAWWYIRNSPREHLGVNEQEARHIEDALALEHSEEPTNLSGRSLDFFKY
RSVWCMAISWMCFNAVFYGLLTWMPTYLSKARGFDLKQMGGASFIIFFAGFVGELIGGWIADKWKEAGGRPNVVMRTLFG
IAAVVATVSIFSVAYVTDPVAVVVLLSSTLFFLRWCGLFWSVPSMLGTRNKVGFLGGVMNLGGNIAGISVPIIVGLIVQA
TGSYFLALMFFAACGIGLLLASTNIDYEKKIPV

Specific function: Uptake of D-glucarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI9945322, Length=365, Percent_Identity=26.5753424657534, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI6912666, Length=363, Percent_Identity=23.4159779614325, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI9966811, Length=370, Percent_Identity=25.1351351351351, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI154350196, Length=387, Percent_Identity=23.5142118863049, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI4885441, Length=366, Percent_Identity=24.3169398907104, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI21322234, Length=362, Percent_Identity=24.585635359116, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI1789152, Length=424, Percent_Identity=28.7735849056604, Blast_Score=174, Evalue=8e-45,
Organism=Escherichia coli, GI2367379, Length=426, Percent_Identity=31.6901408450704, Blast_Score=171, Evalue=6e-44,
Organism=Escherichia coli, GI87082320, Length=392, Percent_Identity=28.0612244897959, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1789515, Length=407, Percent_Identity=29.4840294840295, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI87082071, Length=381, Percent_Identity=26.7716535433071, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI2367193, Length=393, Percent_Identity=22.3918575063613, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1788573, Length=328, Percent_Identity=23.780487804878, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87082310, Length=311, Percent_Identity=25.08038585209, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17554148, Length=353, Percent_Identity=25.7790368271955, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI115533556, Length=410, Percent_Identity=24.1463414634146, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI115533554, Length=410, Percent_Identity=24.1463414634146, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17554962, Length=352, Percent_Identity=25, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17552542, Length=275, Percent_Identity=25.8181818181818, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560030, Length=395, Percent_Identity=21.2658227848101, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17532009, Length=415, Percent_Identity=21.4457831325301, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17564204, Length=249, Percent_Identity=26.9076305220884, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17564202, Length=255, Percent_Identity=27.0588235294118, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17535049, Length=262, Percent_Identity=26.7175572519084, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71997452, Length=305, Percent_Identity=24.9180327868852, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17561498, Length=222, Percent_Identity=25.2252252252252, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI115534558, Length=211, Percent_Identity=25.5924170616114, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI45550460, Length=431, Percent_Identity=25.754060324826, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24639764, Length=447, Percent_Identity=23.2662192393736, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24655255, Length=426, Percent_Identity=24.8826291079812, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24584153, Length=378, Percent_Identity=25.9259259259259, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI20130135, Length=422, Percent_Identity=26.0663507109005, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24655271, Length=402, Percent_Identity=26.3681592039801, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24654215, Length=389, Percent_Identity=25.4498714652956, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI19922400, Length=389, Percent_Identity=25.4498714652956, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24583789, Length=406, Percent_Identity=24.6305418719212, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI28573299, Length=394, Percent_Identity=25.8883248730964, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24658658, Length=412, Percent_Identity=25, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24641682, Length=409, Percent_Identity=24.4498777506112, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI62484226, Length=379, Percent_Identity=24.802110817942, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24648416, Length=383, Percent_Identity=25.8485639686684, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI21356189, Length=383, Percent_Identity=25.8485639686684, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI28573708, Length=371, Percent_Identity=25.8760107816712, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28573707, Length=371, Percent_Identity=25.8760107816712, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI20130167, Length=417, Percent_Identity=22.7817745803357, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24580790, Length=368, Percent_Identity=23.0978260869565, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI19920686, Length=412, Percent_Identity=23.3009708737864, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24658689, Length=421, Percent_Identity=23.0403800475059, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI45552797, Length=430, Percent_Identity=23.2558139534884, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI45550495, Length=391, Percent_Identity=24.5524296675192, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24653727, Length=253, Percent_Identity=26.0869565217391, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24658666, Length=396, Percent_Identity=22.2222222222222, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24658674, Length=368, Percent_Identity=22.2826086956522, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46618; Mature: 46618

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSTSPAAASLAVPRSSVRWKIFLMMLLLVAINYIDRASLSVAMPLIAKEFDLSPAMQGL
CCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ILSSFFWTYAVMQVPGGMLADKYKPRIVIATATVFWGAFQALAAVCTNATSLLLTRLGLG
HHHHHHHHHHHHHCCCCHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AAEAPIYPAGGKLNAIWMTKNERGRGATLLDGGAPLGAALGSLIIAGLISELGSWRLSFV
CCCCCCCCCCCCEEEEEEECCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VAGVGTVLAGFVAWWYIRNSPREHLGVNEQEARHIEDALALEHSEEPTNLSGRSLDFFKY
HHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
RSVWCMAISWMCFNAVFYGLLTWMPTYLSKARGFDLKQMGGASFIIFFAGFVGELIGGWI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHH
ADKWKEAGGRPNVVMRTLFGIAAVVATVSIFSVAYVTDPVAVVVLLSSTLFFLRWCGLFW
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVPSMLGTRNKVGFLGGVMNLGGNIAGISVPIIVGLIVQATGSYFLALMFFAACGIGLLL
HHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASTNIDYEKKIPV
CCCCCCCCCCCCC
>Mature Secondary Structure
MQSTSPAAASLAVPRSSVRWKIFLMMLLLVAINYIDRASLSVAMPLIAKEFDLSPAMQGL
CCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ILSSFFWTYAVMQVPGGMLADKYKPRIVIATATVFWGAFQALAAVCTNATSLLLTRLGLG
HHHHHHHHHHHHHCCCCHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AAEAPIYPAGGKLNAIWMTKNERGRGATLLDGGAPLGAALGSLIIAGLISELGSWRLSFV
CCCCCCCCCCCCEEEEEEECCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VAGVGTVLAGFVAWWYIRNSPREHLGVNEQEARHIEDALALEHSEEPTNLSGRSLDFFKY
HHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
RSVWCMAISWMCFNAVFYGLLTWMPTYLSKARGFDLKQMGGASFIIFFAGFVGELIGGWI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHH
ADKWKEAGGRPNVVMRTLFGIAAVVATVSIFSVAYVTDPVAVVVLLSSTLFFLRWCGLFW
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVPSMLGTRNKVGFLGGVMNLGGNIAGISVPIIVGLIVQATGSYFLALMFFAACGIGLLL
HHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASTNIDYEKKIPV
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]