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The map label for this gene is erg3 [H]

Identifier: 94312806

GI number: 94312806

Start: 423142

End: 424065

Strand: Reverse

Name: erg3 [H]

Synonym: Rmet_3878

Alternate gene names: 94312806

Gene position: 424065-423142 (Counterclockwise)

Preceding gene: 94312813

Following gene: 94312805

Centisome position: 16.44

GC content: 64.83

Gene sequence:

>924_bases
ATGGTCATCACTGGCAAGTTTGCGATGTACGTCACCGCGTTCGTCGTCACCGTCTCGCTGATCGAGGCATTCGTCCTGTG
GCGCAAGCGTCGCGACGGCGTCAAACCGTTCTCGTGGAACGAGGTCTGGCTGTCCTTGGCCGACCTGGCCGGACGCAAGC
TGTCGGTGCTGCTGCCGCTGTCGCTGGCCGCGCCGGTTTTCTCGTTCGCCTGGGATCACCGCCTGTTCACGATCACGCTG
AACAGCGCGCTGGCTGTCTTCCTGCTCTTCGTCGGCCAGGAGTTCTGCTACTACTGGTACCACCGTGCCGCGCACCGCAT
CCGCTTCTTCTGGGCCACGCACGCCGTGCATCACTCCCCCAACCAGCTCACGCTCACGTCCGCGTACCGGCTGGGCTGGA
CCGGCAAGCTCACCGGCAGCGCCGTGTTCTTCGCGCCGCTGGTCCTGCTCGGCGTGCGCCCCGAAGTGGTGCTGGCCACG
CTTTCGCTCAACCTGCTCTACCAGTTCTGGCTGCATAACGACTGGATGCCCAAGCTCGGCTGGTTTGAGTACGTGTTCAA
CACGCCGTCGGCCCACCGCGTCCATCACGCGTCGAACATCGACTACCTCGACGCCAACTACGGTGGCGTGCTGATCATCT
TCGACCGCCTGTTCGGCACCTATGTGGAAGAGCGCGCCGATGAACCATGCCGCTACGGACTGGTCCATCCGACCACCACG
CAGAACCCGATCGTCAACCAGTTCGAGCACTGGGTCAGCCTGGGTCGGGACATGGCCTCCGCCTCGAAGCTCTGGCACGC
CGCCGCATACCTGATCATGCCGCCGGGCTGGGCGCCCAATGGCAAGGGCACCACCACCGAGATCCTGCGCCGCCAGCAAG
AGGAACTGCGGCAGGCCGGATGGCAGCGGCCGGGCGTTGTCTAG

Upstream 100 bases:

>100_bases
GGATTCCCGGATCGCCCGCCGCTAGAGTTGCCTCACCGATGCGGCACAACCGCGCCCCGCACTGAATCCACCGAATACAC
AGATTTCACCGAGGTTCACC

Downstream 100 bases:

>100_bases
ATGCTGAAAACGCCGGGCCAGAGCGCCAAACCCCTCGGAGGGCTCACGGCCCGGTGGGCAGTGATCGTATGATTAGTGTT
TTCGCCATACCCTGCCTCTA

Product: putative sterol desaturase

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MVITGKFAMYVTAFVVTVSLIEAFVLWRKRRDGVKPFSWNEVWLSLADLAGRKLSVLLPLSLAAPVFSFAWDHRLFTITL
NSALAVFLLFVGQEFCYYWYHRAAHRIRFFWATHAVHHSPNQLTLTSAYRLGWTGKLTGSAVFFAPLVLLGVRPEVVLAT
LSLNLLYQFWLHNDWMPKLGWFEYVFNTPSAHRVHHASNIDYLDANYGGVLIIFDRLFGTYVEERADEPCRYGLVHPTTT
QNPIVNQFEHWVSLGRDMASASKLWHAAAYLIMPPGWAPNGKGTTTEILRRQQEELRQAGWQRPGVV

Sequences:

>Translated_307_residues
MVITGKFAMYVTAFVVTVSLIEAFVLWRKRRDGVKPFSWNEVWLSLADLAGRKLSVLLPLSLAAPVFSFAWDHRLFTITL
NSALAVFLLFVGQEFCYYWYHRAAHRIRFFWATHAVHHSPNQLTLTSAYRLGWTGKLTGSAVFFAPLVLLGVRPEVVLAT
LSLNLLYQFWLHNDWMPKLGWFEYVFNTPSAHRVHHASNIDYLDANYGGVLIIFDRLFGTYVEERADEPCRYGLVHPTTT
QNPIVNQFEHWVSLGRDMASASKLWHAAAYLIMPPGWAPNGKGTTTEILRRQQEELRQAGWQRPGVV
>Mature_307_residues
MVITGKFAMYVTAFVVTVSLIEAFVLWRKRRDGVKPFSWNEVWLSLADLAGRKLSVLLPLSLAAPVFSFAWDHRLFTITL
NSALAVFLLFVGQEFCYYWYHRAAHRIRFFWATHAVHHSPNQLTLTSAYRLGWTGKLTGSAVFFAPLVLLGVRPEVVLAT
LSLNLLYQFWLHNDWMPKLGWFEYVFNTPSAHRVHHASNIDYLDANYGGVLIIFDRLFGTYVEERADEPCRYGLVHPTTT
QNPIVNQFEHWVSLGRDMASASKLWHAAAYLIMPPGWAPNGKGTTTEILRRQQEELRQAGWQRPGVV

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=289, Percent_Identity=34.9480968858132, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI25144659, Length=242, Percent_Identity=32.2314049586777, Blast_Score=114, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 35183; Mature: 35183

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVITGKFAMYVTAFVVTVSLIEAFVLWRKRRDGVKPFSWNEVWLSLADLAGRKLSVLLPL
CEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEEECH
SLAAPVFSFAWDHRLFTITLNSALAVFLLFVGQEFCYYWYHRAAHRIRFFWATHAVHHSP
HHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHCCCC
NQLTLTSAYRLGWTGKLTGSAVFFAPLVLLGVRPEVVLATLSLNLLYQFWLHNDWMPKLG
CEEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
WFEYVFNTPSAHRVHHASNIDYLDANYGGVLIIFDRLFGTYVEERADEPCRYGLVHPTTT
HHHHHHCCCCCCEEECCCCCCEEECCCCCEEEEHHHHHHHHHHHHCCCCHHCCCCCCCCC
QNPIVNQFEHWVSLGRDMASASKLWHAAAYLIMPPGWAPNGKGTTTEILRRQQEELRQAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCC
WQRPGVV
CCCCCCC
>Mature Secondary Structure
MVITGKFAMYVTAFVVTVSLIEAFVLWRKRRDGVKPFSWNEVWLSLADLAGRKLSVLLPL
CEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEEECH
SLAAPVFSFAWDHRLFTITLNSALAVFLLFVGQEFCYYWYHRAAHRIRFFWATHAVHHSP
HHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHCCCC
NQLTLTSAYRLGWTGKLTGSAVFFAPLVLLGVRPEVVLATLSLNLLYQFWLHNDWMPKLG
CEEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
WFEYVFNTPSAHRVHHASNIDYLDANYGGVLIIFDRLFGTYVEERADEPCRYGLVHPTTT
HHHHHHCCCCCCEEECCCCCCEEECCCCCEEEEHHHHHHHHHHHHCCCCHHCCCCCCCCC
QNPIVNQFEHWVSLGRDMASASKLWHAAAYLIMPPGWAPNGKGTTTEILRRQQEELRQAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCC
WQRPGVV
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]