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The map label for this gene is aidB [H]

Identifier: 94312720

GI number: 94312720

Start: 327888

End: 329678

Strand: Reverse

Name: aidB [H]

Synonym: Rmet_3790

Alternate gene names: 94312720

Gene position: 329678-327888 (Counterclockwise)

Preceding gene: 94312721

Following gene: 94312705

Centisome position: 12.78

GC content: 64.1

Gene sequence:

>1791_bases
ATGTCCTTTGAACCCGACTACGCCGATTACGTTAGCCCCCGTCCAGCGCGCTCCCACCAGAGTTCGCAGCATCTCGCGCC
AGACTGCGCGGGGCTCGACTTCCTTGCCCTTGACCGGGGTCTTCAGGACATGCTGCGGCTCTATCTCCCGGCCGACGCGC
ACGCTCACCTGCTGCCACACCTGGAACGCATGGGCAAACTGGCAGGCGGTCGACTGAACACGCTTGCCATCGTTGCGGAC
AAGCACGCACCGGTGCTGCACGTACGCACTCGCTGGGGCGAAGATGCTGACTGGATCGAGTATCACCCCGCCTATCAGGA
GATGGAGCATATTGCCTTCGGTGACTTCCAGTTCCATGCGATGAGCCATCGTGGCGGTGTGCTGGGATGGAAAGAGCCAC
TGCCGGCGGCGGCCAAGTATGCATTCCAGTACTTGTTCGTACAGGCAGAGTTCGGACAAATGTGCCCGATCAGCGTGTCC
GATACATCGATCCACCTGATTCGCAAGTACGGCAGCGCCGCGCTGCAGGAAAAGCTGCTGCCGCGCCTGCTCTCGTCGGA
CCCGGGCACCATGTGGAAGGGCACGCAATTCATGACCGAGAAGGCCGGCGGATCGGATGTTGGCGCCATCGAGACCGTAG
CGCGCGAGGAGGATGGCGAGTGGCGCCTGTACGGAGAAAAATGGTTCTGCTCGCATACCGATGCCGATATCGCGCTTCTG
CTGGCTCGTCCCGAGGGGGCGGTGGATGGCACGCGCGGTCTGGCGCTGTTCGCGCTGCCCCGTACCCTCGATGATGGCAG
CCGTAACGCCTATCGCATCGTGCGGCTCAAGGACAAGCTGGGCACACGCTCGATGGCTAGCGGCGAGATACGCCTTGATG
GGGCCGTGGCCTACCTGGTGGGTGATCCGACGCAAGGGCTGAAGCAGATGATGGAGCAGGTCAACCTGTCCAGGCTGTCG
CACGCGGTGCGCGCGGCCGCCATGATGCGTCGCTGCCTGAATGAAGCCCTTGTCGCGGCAAGACACCGCCGCGCCTTCGG
CCGCGAAGTCGTCGGCCATGCGTTGCTGCGCCGGCAATTACTCAAAGTCATGGTGCCGACCGAAGCCGCACTATCGATGG
TCATGGCTACTGCGGACATCATGGCCCGGGCTGGCAAGGGCGACAAGACCGCGGCGCTGGCGCTTCGCCTCCTTACGCCG
CTGCTCAAGCTGCGGACCTGCCGCGATAACATCGAAGTTGCTACGGGTGCGATGGAGGTACGAGGCGGCAACGGCTATAT
CGAGGACTTCGTCAATGCGCGTCTGGTGCGTGACGCCCACATTGGGGTGTTGTGGGAGGGGACCAGCAACATCAATGCGC
TCGATGCCATCCAGCGTGCGGTGCGCAAGGATGGTGCGCAACACGCGCTATTGGCGTTGATGTCGGCGCGGCTCGAGCAA
GCAACGCATTTGCCGGCGGACCTGAGAGCAGTCTTGCAGCGCAGCTTGAGCCGAGCGATCGCGCTGGCCGAAACCGTTGC
CGGCGATGCAGCGCTGGAGGCAGAAGTCCGCCGCGCAGCAAGCGCGCTCTACTACGCGACGGCAGCAACCATCCTTGCCT
GGGAAGCCACGCAGCCCGGTGTGGACGGGCGTCGCCTGCTGCTCGCGCATGCTGTCCTCGAGCACTATCTGCTGCCCCGC
GATCCGCTCGGTTCGCCGGAGTCCAAGGGGGAATCGGAGGCAGACCGGTTGCTCCTGCAGGGTGAACCGGTGAGCCTGGA
GGCCGCTGGCGTCGCGTTGACCGGGCGATAG

Upstream 100 bases:

>100_bases
TGCCGAACTTTCCCGCCTGCGCGAGGCCGGGGCCATCTGATTTCCGTATGCCCGGGACCGGGCGCGGATTGCATCCAACC
TGTGCCAGTGAGATTTCCAT

Downstream 100 bases:

>100_bases
CCTGAAGATCGTCGTCGTGCGTGGCAGATCTGCATTGCCCTCGCGGTGACATGACTGCTGGAACGCCGCGACAAGGCCAC
GGCCAAACGCGCCTTCCTGC

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 596; Mature: 595

Protein sequence:

>596_residues
MSFEPDYADYVSPRPARSHQSSQHLAPDCAGLDFLALDRGLQDMLRLYLPADAHAHLLPHLERMGKLAGGRLNTLAIVAD
KHAPVLHVRTRWGEDADWIEYHPAYQEMEHIAFGDFQFHAMSHRGGVLGWKEPLPAAAKYAFQYLFVQAEFGQMCPISVS
DTSIHLIRKYGSAALQEKLLPRLLSSDPGTMWKGTQFMTEKAGGSDVGAIETVAREEDGEWRLYGEKWFCSHTDADIALL
LARPEGAVDGTRGLALFALPRTLDDGSRNAYRIVRLKDKLGTRSMASGEIRLDGAVAYLVGDPTQGLKQMMEQVNLSRLS
HAVRAAAMMRRCLNEALVAARHRRAFGREVVGHALLRRQLLKVMVPTEAALSMVMATADIMARAGKGDKTAALALRLLTP
LLKLRTCRDNIEVATGAMEVRGGNGYIEDFVNARLVRDAHIGVLWEGTSNINALDAIQRAVRKDGAQHALLALMSARLEQ
ATHLPADLRAVLQRSLSRAIALAETVAGDAALEAEVRRAASALYYATAATILAWEATQPGVDGRRLLLAHAVLEHYLLPR
DPLGSPESKGESEADRLLLQGEPVSLEAAGVALTGR

Sequences:

>Translated_596_residues
MSFEPDYADYVSPRPARSHQSSQHLAPDCAGLDFLALDRGLQDMLRLYLPADAHAHLLPHLERMGKLAGGRLNTLAIVAD
KHAPVLHVRTRWGEDADWIEYHPAYQEMEHIAFGDFQFHAMSHRGGVLGWKEPLPAAAKYAFQYLFVQAEFGQMCPISVS
DTSIHLIRKYGSAALQEKLLPRLLSSDPGTMWKGTQFMTEKAGGSDVGAIETVAREEDGEWRLYGEKWFCSHTDADIALL
LARPEGAVDGTRGLALFALPRTLDDGSRNAYRIVRLKDKLGTRSMASGEIRLDGAVAYLVGDPTQGLKQMMEQVNLSRLS
HAVRAAAMMRRCLNEALVAARHRRAFGREVVGHALLRRQLLKVMVPTEAALSMVMATADIMARAGKGDKTAALALRLLTP
LLKLRTCRDNIEVATGAMEVRGGNGYIEDFVNARLVRDAHIGVLWEGTSNINALDAIQRAVRKDGAQHALLALMSARLEQ
ATHLPADLRAVLQRSLSRAIALAETVAGDAALEAEVRRAASALYYATAATILAWEATQPGVDGRRLLLAHAVLEHYLLPR
DPLGSPESKGESEADRLLLQGEPVSLEAAGVALTGR
>Mature_595_residues
SFEPDYADYVSPRPARSHQSSQHLAPDCAGLDFLALDRGLQDMLRLYLPADAHAHLLPHLERMGKLAGGRLNTLAIVADK
HAPVLHVRTRWGEDADWIEYHPAYQEMEHIAFGDFQFHAMSHRGGVLGWKEPLPAAAKYAFQYLFVQAEFGQMCPISVSD
TSIHLIRKYGSAALQEKLLPRLLSSDPGTMWKGTQFMTEKAGGSDVGAIETVAREEDGEWRLYGEKWFCSHTDADIALLL
ARPEGAVDGTRGLALFALPRTLDDGSRNAYRIVRLKDKLGTRSMASGEIRLDGAVAYLVGDPTQGLKQMMEQVNLSRLSH
AVRAAAMMRRCLNEALVAARHRRAFGREVVGHALLRRQLLKVMVPTEAALSMVMATADIMARAGKGDKTAALALRLLTPL
LKLRTCRDNIEVATGAMEVRGGNGYIEDFVNARLVRDAHIGVLWEGTSNINALDAIQRAVRKDGAQHALLALMSARLEQA
THLPADLRAVLQRSLSRAIALAETVAGDAALEAEVRRAASALYYATAATILAWEATQPGVDGRRLLLAHAVLEHYLLPRD
PLGSPESKGESEADRLLLQGEPVSLEAAGVALTGR

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=310, Percent_Identity=25.8064516129032, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI226958414, Length=310, Percent_Identity=26.1290322580645, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4501859, Length=320, Percent_Identity=25.3125, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI4557233, Length=300, Percent_Identity=25.6666666666667, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI21361497, Length=308, Percent_Identity=24.3506493506494, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI187960098, Length=264, Percent_Identity=26.8939393939394, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI4557231, Length=264, Percent_Identity=26.8939393939394, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI87082384, Length=411, Percent_Identity=33.3333333333333, Blast_Score=185, Evalue=8e-48,
Organism=Escherichia coli, GI87081958, Length=294, Percent_Identity=24.8299319727891, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI86563383, Length=456, Percent_Identity=31.140350877193, Blast_Score=204, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI86563381, Length=456, Percent_Identity=31.140350877193, Blast_Score=204, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17508101, Length=308, Percent_Identity=23.7012987012987, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17506239, Length=307, Percent_Identity=23.1270358306189, Blast_Score=93, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17538396, Length=309, Percent_Identity=25.8899676375405, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17551932, Length=303, Percent_Identity=27.0627062706271, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17569725, Length=258, Percent_Identity=25.968992248062, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17570075, Length=280, Percent_Identity=24.6428571428571, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17505929, Length=303, Percent_Identity=25.7425742574257, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71990804, Length=258, Percent_Identity=23.2558139534884, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17533517, Length=304, Percent_Identity=23.6842105263158, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17534899, Length=277, Percent_Identity=24.9097472924188, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24666513, Length=334, Percent_Identity=24.251497005988, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21355753, Length=297, Percent_Identity=24.5791245791246, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI21356377, Length=261, Percent_Identity=24.5210727969349, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24660351, Length=263, Percent_Identity=26.615969581749, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281363737, Length=341, Percent_Identity=24.3401759530792, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: NA

Molecular weight: Translated: 65148; Mature: 65016

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFEPDYADYVSPRPARSHQSSQHLAPDCAGLDFLALDRGLQDMLRLYLPADAHAHLLPH
CCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LERMGKLAGGRLNTLAIVADKHAPVLHVRTRWGEDADWIEYHPAYQEMEHIAFGDFQFHA
HHHHHHHCCCCEEEEEEEECCCCCEEEEEECCCCCCCHHHCCCHHHHHHHHCCCCEEEEE
MSHRGGVLGWKEPLPAAAKYAFQYLFVQAEFGQMCPISVSDTSIHLIRKYGSAALQEKLL
ECCCCCCCCCCCCCCHHHHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
PRLLSSDPGTMWKGTQFMTEKAGGSDVGAIETVAREEDGEWRLYGEKWFCSHTDADIALL
HHHHCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHCCCCCEEEECCEEEECCCCCCEEEE
LARPEGAVDGTRGLALFALPRTLDDGSRNAYRIVRLKDKLGTRSMASGEIRLDGAVAYLV
EECCCCCCCCCCCEEEEEECCCCCCCCCCCEEEEEEHHHCCCCCCCCCCEEECCEEEEEE
GDPTQGLKQMMEQVNLSRLSHAVRAAAMMRRCLNEALVAARHRRAFGREVVGHALLRRQL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKVMVPTEAALSMVMATADIMARAGKGDKTAALALRLLTPLLKLRTCRDNIEVATGAMEV
HHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECEEEE
RGGNGYIEDFVNARLVRDAHIGVLWEGTSNINALDAIQRAVRKDGAQHALLALMSARLEQ
ECCCCHHHHHHHHHEEEECEEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
ATHLPADLRAVLQRSLSRAIALAETVAGDAALEAEVRRAASALYYATAATILAWEATQPG
HHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCC
VDGRRLLLAHAVLEHYLLPRDPLGSPESKGESEADRLLLQGEPVSLEAAGVALTGR
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHEEECCCCCEEEECCEEEECC
>Mature Secondary Structure 
SFEPDYADYVSPRPARSHQSSQHLAPDCAGLDFLALDRGLQDMLRLYLPADAHAHLLPH
CCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LERMGKLAGGRLNTLAIVADKHAPVLHVRTRWGEDADWIEYHPAYQEMEHIAFGDFQFHA
HHHHHHHCCCCEEEEEEEECCCCCEEEEEECCCCCCCHHHCCCHHHHHHHHCCCCEEEEE
MSHRGGVLGWKEPLPAAAKYAFQYLFVQAEFGQMCPISVSDTSIHLIRKYGSAALQEKLL
ECCCCCCCCCCCCCCHHHHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
PRLLSSDPGTMWKGTQFMTEKAGGSDVGAIETVAREEDGEWRLYGEKWFCSHTDADIALL
HHHHCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHCCCCCEEEECCEEEECCCCCCEEEE
LARPEGAVDGTRGLALFALPRTLDDGSRNAYRIVRLKDKLGTRSMASGEIRLDGAVAYLV
EECCCCCCCCCCCEEEEEECCCCCCCCCCCEEEEEEHHHCCCCCCCCCCEEECCEEEEEE
GDPTQGLKQMMEQVNLSRLSHAVRAAAMMRRCLNEALVAARHRRAFGREVVGHALLRRQL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKVMVPTEAALSMVMATADIMARAGKGDKTAALALRLLTPLLKLRTCRDNIEVATGAMEV
HHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECEEEE
RGGNGYIEDFVNARLVRDAHIGVLWEGTSNINALDAIQRAVRKDGAQHALLALMSARLEQ
ECCCCHHHHHHHHHEEEECEEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
ATHLPADLRAVLQRSLSRAIALAETVAGDAALEAEVRRAASALYYATAATILAWEATQPG
HHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCC
VDGRRLLLAHAVLEHYLLPRDPLGSPESKGESEADRLLLQGEPVSLEAAGVALTGR
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHEEECCCCCEEEECCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]