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The map label for this gene is galE [H]

Identifier: 94312608

GI number: 94312608

Start: 213312

End: 214331

Strand: Direct

Name: galE [H]

Synonym: Rmet_3676

Alternate gene names: 94312608

Gene position: 213312-214331 (Clockwise)

Preceding gene: 94312607

Following gene: 94312610

Centisome position: 8.27

GC content: 60.49

Gene sequence:

>1020_bases
ATGGCTGAGACCCTATTGCTGACCGGCGCGACCGGATATATCGCCTCCCACACATGGGTGGCGTTGCATGAAGCAGGCTA
CAACGTGATCGGGCTCGATAATCTCTGCAATAGCAGCGCCGAGGTCGTGAACCGGCTGGCGAAGATTACTGGCACGACAC
CGCATTTTGTGGAAGGCGACGTGCGCGACCGCGCACTGCTGGACCGGCTGTTGGCCGAGCACAAGATCAACGGCGCCATC
CATTTCGCCGCCCTGAAAGCGGTGGGAGAGTCGGTCAGTAAACCGCTCGAGTATTACGGAAACAACCTTGAGGGTTTGAT
CACACTGTGCTCGGCGATGCAGTCGGCGGGTGTCCGGCAATTGGTGTTCAGTTCCTCGGCCACGGTGTACGGCAATCCCC
ATGCGATGCCGATTCTCGAGAATTTCCCTCTATCGGCCACCAATCCGTACGGCCAGACCAAACTGATGGGGGAGCAGATC
CTGCGTGATCTGGAAATTTCCGATCCGGAATGGAAAATCGCCTTCCTGCGTTATTTCAACCCGGTAGGCGCACATGAGAG
CGGAACGATTGGCGAGGATCCGGGCGGCATTCCGAACAATCTGATGCCCTATGTGGCGCAGGTGGCCGCCGGGCGGCGCG
AAAAGCTGAGTGTGTATGGCGGTGACTATCCGACGCCCGATGGCACCGGGGTGCGCGACTATATCCATGTCAGCGATCTG
GCCGATGGCCATGTGGCAGCGCTGGCCTACCTTGGCAAGAACTCGCGCGGCATGACCGTGAATCTTGGCACGGGCCGTGG
ATATAGTGTTCTGGAAGTTGTGAAGGCCTACGAACGAGCCAGCGGGCGGCCGATACCCTACGAAATCGTCGCGCGTCGCC
CCGGCGATATCGCGGAATGCTATGCCGATCCGGGTATTGCCCGCACGCTGCTTGGCTGGAGCGCCCGCCACGACCTCGAC
CGCATGTGCGAGGACTCCTGGCGCTGGCAGTCGTTGAACCCGGTGGGGTTCACGGCTTAG

Upstream 100 bases:

>100_bases
GCGCATGATACATATCGCAGCCGTAAAGACGCACGGTTATGATGGCAGCCCACTCGGTGAGCGAGCGACGTGAACCCAAT
CCAGATCCTTGAAGATTTCC

Downstream 100 bases:

>100_bases
CGGCGCTATCAAAATGATTCTGGCGTCGTTGCGCGGCCTTGGCCGGTCTACTTGTACTGTCTGCGGCCGCGCGTCTAGCC
AGAACCGCTTCGCTTCATCT

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MAETLLLTGATGYIASHTWVALHEAGYNVIGLDNLCNSSAEVVNRLAKITGTTPHFVEGDVRDRALLDRLLAEHKINGAI
HFAALKAVGESVSKPLEYYGNNLEGLITLCSAMQSAGVRQLVFSSSATVYGNPHAMPILENFPLSATNPYGQTKLMGEQI
LRDLEISDPEWKIAFLRYFNPVGAHESGTIGEDPGGIPNNLMPYVAQVAAGRREKLSVYGGDYPTPDGTGVRDYIHVSDL
ADGHVAALAYLGKNSRGMTVNLGTGRGYSVLEVVKAYERASGRPIPYEIVARRPGDIAECYADPGIARTLLGWSARHDLD
RMCEDSWRWQSLNPVGFTA

Sequences:

>Translated_339_residues
MAETLLLTGATGYIASHTWVALHEAGYNVIGLDNLCNSSAEVVNRLAKITGTTPHFVEGDVRDRALLDRLLAEHKINGAI
HFAALKAVGESVSKPLEYYGNNLEGLITLCSAMQSAGVRQLVFSSSATVYGNPHAMPILENFPLSATNPYGQTKLMGEQI
LRDLEISDPEWKIAFLRYFNPVGAHESGTIGEDPGGIPNNLMPYVAQVAAGRREKLSVYGGDYPTPDGTGVRDYIHVSDL
ADGHVAALAYLGKNSRGMTVNLGTGRGYSVLEVVKAYERASGRPIPYEIVARRPGDIAECYADPGIARTLLGWSARHDLD
RMCEDSWRWQSLNPVGFTA
>Mature_338_residues
AETLLLTGATGYIASHTWVALHEAGYNVIGLDNLCNSSAEVVNRLAKITGTTPHFVEGDVRDRALLDRLLAEHKINGAIH
FAALKAVGESVSKPLEYYGNNLEGLITLCSAMQSAGVRQLVFSSSATVYGNPHAMPILENFPLSATNPYGQTKLMGEQIL
RDLEISDPEWKIAFLRYFNPVGAHESGTIGEDPGGIPNNLMPYVAQVAAGRREKLSVYGGDYPTPDGTGVRDYIHVSDLA
DGHVAALAYLGKNSRGMTVNLGTGRGYSVLEVVKAYERASGRPIPYEIVARRPGDIAECYADPGIARTLLGWSARHDLDR
MCEDSWRWQSLNPVGFTA

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=344, Percent_Identity=56.3953488372093, Blast_Score=388, Evalue=1e-108,
Organism=Homo sapiens, GI56118217, Length=344, Percent_Identity=56.3953488372093, Blast_Score=388, Evalue=1e-108,
Organism=Homo sapiens, GI189083684, Length=344, Percent_Identity=56.3953488372093, Blast_Score=388, Evalue=1e-108,
Organism=Homo sapiens, GI7657641, Length=277, Percent_Identity=27.7978339350181, Blast_Score=93, Evalue=3e-19,
Organism=Escherichia coli, GI1786974, Length=334, Percent_Identity=54.7904191616767, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI48994969, Length=357, Percent_Identity=25.2100840336134, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71982035, Length=345, Percent_Identity=51.5942028985507, Blast_Score=348, Evalue=3e-96,
Organism=Caenorhabditis elegans, GI71982038, Length=347, Percent_Identity=51.2968299711816, Blast_Score=347, Evalue=5e-96,
Organism=Saccharomyces cerevisiae, GI6319493, Length=345, Percent_Identity=50.4347826086956, Blast_Score=335, Evalue=4e-93,
Organism=Drosophila melanogaster, GI19923002, Length=343, Percent_Identity=54.8104956268222, Blast_Score=378, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36735; Mature: 36604

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETLLLTGATGYIASHTWVALHEAGYNVIGLDNLCNSSAEVVNRLAKITGTTPHFVEGD
CCCEEEEECCCCHHHCCEEEEEECCCCCEEEHHHHCCCHHHHHHHHHHHCCCCCCCCCCC
VRDRALLDRLLAEHKINGAIHFAALKAVGESVSKPLEYYGNNLEGLITLCSAMQSAGVRQ
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHH
LVFSSSATVYGNPHAMPILENFPLSATNPYGQTKLMGEQILRDLEISDPEWKIAFLRYFN
HHHCCCCEEECCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEHEECCC
PVGAHESGTIGEDPGGIPNNLMPYVAQVAAGRREKLSVYGGDYPTPDGTGVRDYIHVSDL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHEEEECCC
ADGHVAALAYLGKNSRGMTVNLGTGRGYSVLEVVKAYERASGRPIPYEIVARRPGDIAEC
CCCHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCHHEEECCCCCHHHH
YADPGIARTLLGWSARHDLDRMCEDSWRWQSLNPVGFTA
HCCCCHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
AETLLLTGATGYIASHTWVALHEAGYNVIGLDNLCNSSAEVVNRLAKITGTTPHFVEGD
CCEEEEECCCCHHHCCEEEEEECCCCCEEEHHHHCCCHHHHHHHHHHHCCCCCCCCCCC
VRDRALLDRLLAEHKINGAIHFAALKAVGESVSKPLEYYGNNLEGLITLCSAMQSAGVRQ
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHH
LVFSSSATVYGNPHAMPILENFPLSATNPYGQTKLMGEQILRDLEISDPEWKIAFLRYFN
HHHCCCCEEECCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEHEECCC
PVGAHESGTIGEDPGGIPNNLMPYVAQVAAGRREKLSVYGGDYPTPDGTGVRDYIHVSDL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHEEEECCC
ADGHVAALAYLGKNSRGMTVNLGTGRGYSVLEVVKAYERASGRPIPYEIVARRPGDIAEC
CCCHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCHHEEECCCCCHHHH
YADPGIARTLLGWSARHDLDRMCEDSWRWQSLNPVGFTA
HCCCCHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]