Definition Cupriavidus metallidurans CH34 chromosome, complete genome.
Accession NC_007973
Length 3,928,089

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The map label for this gene is 94312468

Identifier: 94312468

GI number: 94312468

Start: 3835087

End: 3835599

Strand: Reverse

Name: 94312468

Synonym: Rmet_3537

Alternate gene names: NA

Gene position: 3835599-3835087 (Counterclockwise)

Preceding gene: 94312470

Following gene: 94312463

Centisome position: 97.65

GC content: 60.43

Gene sequence:

>513_bases
ATGTCGGACAAGGGCACGGACACCAAAGATAAAGAGAAGAAGGCGGGAAAGAAGAAGACCGCCAGTGATCGCATCGAGGT
GCGCCAGTCGGGCGTGCATGGCAAGGGCGTCTACGCGATCGGCCAAATCGCCGAGGGTGAGCGCGTGATCGAGTACAAGG
GCGAGCACATCTCCTGGAAGGAAGCGCTCAAGCGCCATCCGCACGATCCGAACGACCCGAATCACACTTTCTATTTCAGT
CTGGACGACGGCGACGTGATCGACGCCAAGTTCGGCGGAAACCGCGCGCGCTGGATCAATCACGCCTGCGATCCGAACTG
CGAGGCGCGCGAGAAGAAGGGGCGCGTGTTCATCCACGCACTGCGCGATATCGAGCCGGGCGAGGAACTGTTCTACGACT
ACGGTCTGGTGATCGACGCGCGCTACACAAAGAAGCTCAAGCAGGAATACGAGTGCCGCTGCGGCAGCCCCAAGTGCCGT
GGCACGATGCTGGCGCCGAAGGACAAGAAGTAA

Upstream 100 bases:

>100_bases
TGAGGTATACGTCCGTCGTGCGTATACCTGAGTGGGCAGCACGGGTATCATCCGGTTCGCGCCGGACTGGGCCGGCCGCC
ATCGCCACGGGAATCAGCAC

Downstream 100 bases:

>100_bases
GGCAATCGGGGCGCAAGGGCCCCGCGTGACACATCAGGCTGCGGTGCCGGGGGCTTCGCACGGAATCCGGATCACGAAAC
GCATGGTCGGCGGGCGCTCC

Product: putative histone-lysine N-methyltransferase

Products: NA

Alternate protein names: Histone-Lysine N-Methyltransferase; SET Domain-Containing Protein; SET Domain Protein; Set Domain Protein; HistoNe-Lysine N-Methyltransferase H3 Lysine-4 Specific; Setd1a Protein; Nuclear Protein Set; Zinc Finger Protein

Number of amino acids: Translated: 170; Mature: 169

Protein sequence:

>170_residues
MSDKGTDTKDKEKKAGKKKTASDRIEVRQSGVHGKGVYAIGQIAEGERVIEYKGEHISWKEALKRHPHDPNDPNHTFYFS
LDDGDVIDAKFGGNRARWINHACDPNCEAREKKGRVFIHALRDIEPGEELFYDYGLVIDARYTKKLKQEYECRCGSPKCR
GTMLAPKDKK

Sequences:

>Translated_170_residues
MSDKGTDTKDKEKKAGKKKTASDRIEVRQSGVHGKGVYAIGQIAEGERVIEYKGEHISWKEALKRHPHDPNDPNHTFYFS
LDDGDVIDAKFGGNRARWINHACDPNCEAREKKGRVFIHALRDIEPGEELFYDYGLVIDARYTKKLKQEYECRCGSPKCR
GTMLAPKDKK
>Mature_169_residues
SDKGTDTKDKEKKAGKKKTASDRIEVRQSGVHGKGVYAIGQIAEGERVIEYKGEHISWKEALKRHPHDPNDPNHTFYFSL
DDGDVIDAKFGGNRARWINHACDPNCEAREKKGRVFIHALRDIEPGEELFYDYGLVIDARYTKKLKQEYECRCGSPKCRG
TMLAPKDKK

Specific function: Unknown

COG id: COG2940

COG function: function code R; Proteins containing SET domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI56550039, Length=147, Percent_Identity=38.0952380952381, Blast_Score=98, Evalue=3e-21,
Organism=Homo sapiens, GI7662046, Length=147, Percent_Identity=39.4557823129252, Blast_Score=95, Evalue=2e-20,
Organism=Homo sapiens, GI110349788, Length=134, Percent_Identity=35.0746268656716, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI210032580, Length=139, Percent_Identity=34.5323741007194, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI19913358, Length=136, Percent_Identity=37.5, Blast_Score=77, Evalue=6e-15,
Organism=Homo sapiens, GI19913350, Length=136, Percent_Identity=37.5, Blast_Score=77, Evalue=6e-15,
Organism=Homo sapiens, GI19913348, Length=136, Percent_Identity=37.5, Blast_Score=77, Evalue=6e-15,
Organism=Homo sapiens, GI109633019, Length=136, Percent_Identity=37.5, Blast_Score=77, Evalue=6e-15,
Organism=Homo sapiens, GI156142197, Length=147, Percent_Identity=35.3741496598639, Blast_Score=75, Evalue=2e-14,
Organism=Homo sapiens, GI156142199, Length=147, Percent_Identity=35.3741496598639, Blast_Score=75, Evalue=2e-14,
Organism=Homo sapiens, GI91718902, Length=158, Percent_Identity=32.2784810126582, Blast_Score=75, Evalue=2e-14,
Organism=Homo sapiens, GI224465233, Length=154, Percent_Identity=36.3636363636364, Blast_Score=75, Evalue=2e-14,
Organism=Homo sapiens, GI27477095, Length=151, Percent_Identity=33.112582781457, Blast_Score=74, Evalue=6e-14,
Organism=Homo sapiens, GI55741677, Length=155, Percent_Identity=30.3225806451613, Blast_Score=73, Evalue=1e-13,
Organism=Homo sapiens, GI19923586, Length=151, Percent_Identity=33.112582781457, Blast_Score=70, Evalue=8e-13,
Organism=Homo sapiens, GI197313748, Length=152, Percent_Identity=30.2631578947368, Blast_Score=67, Evalue=8e-12,
Organism=Homo sapiens, GI4507321, Length=183, Percent_Identity=27.3224043715847, Blast_Score=66, Evalue=1e-11,
Organism=Homo sapiens, GI21361095, Length=136, Percent_Identity=34.5588235294118, Blast_Score=65, Evalue=3e-11,
Organism=Homo sapiens, GI23510384, Length=110, Percent_Identity=38.1818181818182, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17552316, Length=144, Percent_Identity=35.4166666666667, Blast_Score=85, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17552318, Length=144, Percent_Identity=35.4166666666667, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193210440, Length=151, Percent_Identity=36.4238410596026, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17552320, Length=144, Percent_Identity=35.4166666666667, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI25148423, Length=137, Percent_Identity=40.1459854014599, Blast_Score=74, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI25148426, Length=137, Percent_Identity=40.1459854014599, Blast_Score=74, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71993684, Length=140, Percent_Identity=32.1428571428571, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17565204, Length=160, Percent_Identity=31.25, Blast_Score=71, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193202392, Length=161, Percent_Identity=34.1614906832298, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25141373, Length=161, Percent_Identity=34.1614906832298, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6321911, Length=140, Percent_Identity=39.2857142857143, Blast_Score=97, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6322293, Length=144, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=1e-12,
Organism=Drosophila melanogaster, GI62472551, Length=147, Percent_Identity=38.0952380952381, Blast_Score=96, Evalue=8e-21,
Organism=Drosophila melanogaster, GI17136558, Length=147, Percent_Identity=38.0952380952381, Blast_Score=96, Evalue=8e-21,
Organism=Drosophila melanogaster, GI19550181, Length=147, Percent_Identity=38.0952380952381, Blast_Score=96, Evalue=8e-21,
Organism=Drosophila melanogaster, GI19550184, Length=147, Percent_Identity=38.0952380952381, Blast_Score=96, Evalue=9e-21,
Organism=Drosophila melanogaster, GI17136556, Length=147, Percent_Identity=38.0952380952381, Blast_Score=96, Evalue=9e-21,
Organism=Drosophila melanogaster, GI28571451, Length=150, Percent_Identity=34, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24639197, Length=150, Percent_Identity=34, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17737643, Length=134, Percent_Identity=35.8208955223881, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24641786, Length=133, Percent_Identity=35.3383458646617, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281360813, Length=133, Percent_Identity=35.3383458646617, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24650756, Length=151, Percent_Identity=34.4370860927152, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI18543183, Length=135, Percent_Identity=31.1111111111111, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI161078181, Length=153, Percent_Identity=30.0653594771242, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 19382; Mature: 19251

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS50280 SET ; PS50868 POST_SET

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MSDKGTDTKDKEKKAGKKKTASDRIEVRQSGVHGKGVYAIGQIAEGERVIEYKGEHISWK
CCCCCCCCCHHHHHCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCEEEEECCCEECHH
EALKRHPHDPNDPNHTFYFSLDDGDVIDAKFGGNRARWINHACDPNCEAREKKGRVFIHA
HHHHCCCCCCCCCCEEEEEEECCCCEEEEEECCCHHEEECCCCCCCCCCHHCCCCEEEEE
LRDIEPGEELFYDYGLVIDARYTKKLKQEYECRCGSPKCRGTMLAPKDKK
ECCCCCCHHHHHHCCEEEEHHHHHHHHHHHHCCCCCCCCCEEECCCCCCC
>Mature Secondary Structure 
SDKGTDTKDKEKKAGKKKTASDRIEVRQSGVHGKGVYAIGQIAEGERVIEYKGEHISWK
CCCCCCCCHHHHHCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCEEEEECCCEECHH
EALKRHPHDPNDPNHTFYFSLDDGDVIDAKFGGNRARWINHACDPNCEAREKKGRVFIHA
HHHHCCCCCCCCCCEEEEEEECCCCEEEEEECCCHHEEECCCCCCCCCCHHCCCCEEEEE
LRDIEPGEELFYDYGLVIDARYTKKLKQEYECRCGSPKCRGTMLAPKDKK
ECCCCCCHHHHHHCCEEEEHHHHHHHHHHHHCCCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA