| Definition | Cupriavidus metallidurans CH34 chromosome, complete genome. |
|---|---|
| Accession | NC_007973 |
| Length | 3,928,089 |
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The map label for this gene is livF11 [H]
Identifier: 94312441
GI number: 94312441
Start: 3800134
End: 3800877
Strand: Reverse
Name: livF11 [H]
Synonym: Rmet_3510
Alternate gene names: 94312441
Gene position: 3800877-3800134 (Counterclockwise)
Preceding gene: 94312442
Following gene: 94312439
Centisome position: 96.76
GC content: 63.84
Gene sequence:
>744_bases ATGAGTCTGATTCTGGAAGTGAAGGACTTGCATGTCCGCTACGGGAAGGTCGAGGCGGTGCATGGCGCGAACCTCAAGGT TGAGGCAGGCAAGATCGTGACCGTGATCGGGCCGAACGGGGCCGGCAAGTCGACGATGCTGAATGCCGTGATGGGCGCGC TGCCCGTCAGCGGGTCATCGACCGGATCGGTTCGGTTCCTCGGCCATGACATGGCGGGGATTCCGGTGGAGGGGCGCGTG GCGCGCGGGATGTGTCTGGTGCCGGAGAAGCGTGAACTGTTCGCGTCGATGACCGTCGAGGACAACCTGCTGCTCGGCGC ATTCCGGCGCAAGCGCGCTGGGGAGCGCAACTATCTGGACCAGAAGGATGTGGTGTACGACCTGTTCCCGCGTCTGCGGG AGCGTGCGAAGCAGGAGGCGGGCACGCTGTCCGGTGGCGAGCGCCAGATGCTCGCCGTGGGGCGCGCGCTGATGGCCAAG CCGCAGTTGCTGATGCTCGATGAGCCGAGCCTTGGTCTCGCGCCGCTGATCGTTAAGGAGATCTTCCACATCATCCACAA CCTTCGGCAAACCGGCGTGGCGACGCTGCTGATCGAACAGAATGCGCGGGCGGCGTTGCAGGTGGCTGACTACGGGTATG TGATCGAGACCGGCGACATGGCTATGGAAGGCGAAGCGTCGGCGTTGGCGAGCAATCCAAAGGTGATCGAGACGTACCTG GGGCTGACGAAGAAAGCGGCCTGA
Upstream 100 bases:
>100_bases GGAATTCGGCACGCGCATCGCCGAAGGTGTGCCGGAGGAGGTCCAGAAGAATCCGGCAGTGCTGGAAGCCTATCTGGGCG GCATTGATTGAGGATATGAG
Downstream 100 bases:
>100_bases CCTGCTTTTATATTCTTGTGTTTGATTGACGACGCCATAATGGCGTCGTCTTTATTTGTTGAGCATATAAGAAATTGATG ATCATTCGTATAATGGATGT
Product: leucine/isoleucine/valine ABC transporter ATP-binding protein
Products: ADP; phosphate; L-leucine [Cytoplasm]; ADP; L-valine [Cytoplasm]; L-iso-leucine [Cytoplasm] [C]
Alternate protein names: NA
Number of amino acids: Translated: 247; Mature: 246
Protein sequence:
>247_residues MSLILEVKDLHVRYGKVEAVHGANLKVEAGKIVTVIGPNGAGKSTMLNAVMGALPVSGSSTGSVRFLGHDMAGIPVEGRV ARGMCLVPEKRELFASMTVEDNLLLGAFRRKRAGERNYLDQKDVVYDLFPRLRERAKQEAGTLSGGERQMLAVGRALMAK PQLLMLDEPSLGLAPLIVKEIFHIIHNLRQTGVATLLIEQNARAALQVADYGYVIETGDMAMEGEASALASNPKVIETYL GLTKKAA
Sequences:
>Translated_247_residues MSLILEVKDLHVRYGKVEAVHGANLKVEAGKIVTVIGPNGAGKSTMLNAVMGALPVSGSSTGSVRFLGHDMAGIPVEGRV ARGMCLVPEKRELFASMTVEDNLLLGAFRRKRAGERNYLDQKDVVYDLFPRLRERAKQEAGTLSGGERQMLAVGRALMAK PQLLMLDEPSLGLAPLIVKEIFHIIHNLRQTGVATLLIEQNARAALQVADYGYVIETGDMAMEGEASALASNPKVIETYL GLTKKAA >Mature_246_residues SLILEVKDLHVRYGKVEAVHGANLKVEAGKIVTVIGPNGAGKSTMLNAVMGALPVSGSSTGSVRFLGHDMAGIPVEGRVA RGMCLVPEKRELFASMTVEDNLLLGAFRRKRAGERNYLDQKDVVYDLFPRLRERAKQEAGTLSGGERQMLAVGRALMAKP QLLMLDEPSLGLAPLIVKEIFHIIHNLRQTGVATLLIEQNARAALQVADYGYVIETGDMAMEGEASALASNPKVIETYLG LTKKAA
Specific function: Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids [H]
COG id: COG0410
COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component
Gene ontology:
Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI153792144, Length=172, Percent_Identity=31.3953488372093, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI27477115, Length=232, Percent_Identity=28.448275862069, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI27262624, Length=220, Percent_Identity=29.5454545454545, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI27262626, Length=220, Percent_Identity=29.5454545454545, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI27881501, Length=178, Percent_Identity=30.8988764044944, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI30795238, Length=178, Percent_Identity=30.8988764044944, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI27436953, Length=225, Percent_Identity=29.3333333333333, Blast_Score=76, Evalue=2e-14, Organism=Homo sapiens, GI105990541, Length=206, Percent_Identity=27.6699029126214, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI45446740, Length=167, Percent_Identity=29.940119760479, Blast_Score=74, Evalue=8e-14, Organism=Homo sapiens, GI47078218, Length=167, Percent_Identity=29.940119760479, Blast_Score=74, Evalue=9e-14, Organism=Homo sapiens, GI21536376, Length=234, Percent_Identity=27.3504273504274, Blast_Score=74, Evalue=9e-14, Organism=Homo sapiens, GI46592971, Length=213, Percent_Identity=27.2300469483568, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI116734710, Length=180, Percent_Identity=28.3333333333333, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI46592978, Length=213, Percent_Identity=27.2300469483568, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI46592915, Length=213, Percent_Identity=27.2300469483568, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI46592964, Length=213, Percent_Identity=27.2300469483568, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI46592956, Length=213, Percent_Identity=27.2300469483568, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI46592898, Length=213, Percent_Identity=27.2300469483568, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI150417984, Length=188, Percent_Identity=28.1914893617021, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI9961250, Length=182, Percent_Identity=27.4725274725275, Blast_Score=65, Evalue=4e-11, Organism=Homo sapiens, GI4505771, Length=182, Percent_Identity=27.4725274725275, Blast_Score=65, Evalue=5e-11, Organism=Homo sapiens, GI255708477, Length=242, Percent_Identity=28.099173553719, Blast_Score=65, Evalue=5e-11, Organism=Homo sapiens, GI9961252, Length=182, Percent_Identity=27.4725274725275, Blast_Score=65, Evalue=5e-11, Organism=Homo sapiens, GI148612844, Length=242, Percent_Identity=28.099173553719, Blast_Score=65, Evalue=5e-11, Organism=Homo sapiens, GI11967969, Length=219, Percent_Identity=26.027397260274, Blast_Score=65, Evalue=6e-11, Organism=Escherichia coli, GI87082268, Length=239, Percent_Identity=43.9330543933054, Blast_Score=206, Evalue=1e-54, Organism=Escherichia coli, GI1789593, Length=239, Percent_Identity=31.3807531380753, Blast_Score=119, Evalue=2e-28, Organism=Escherichia coli, GI1789864, Length=252, Percent_Identity=31.3492063492063, Blast_Score=118, Evalue=3e-28, Organism=Escherichia coli, GI1787029, Length=233, Percent_Identity=27.4678111587983, Blast_Score=102, Evalue=2e-23, Organism=Escherichia coli, GI1787792, Length=252, Percent_Identity=27.3809523809524, Blast_Score=99, Evalue=3e-22, Organism=Escherichia coli, GI1787089, Length=229, Percent_Identity=26.6375545851528, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1789672, Length=250, Percent_Identity=25.6, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1789991, Length=243, Percent_Identity=26.3374485596708, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1790190, Length=212, Percent_Identity=29.2452830188679, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1786319, Length=247, Percent_Identity=30.3643724696356, Blast_Score=91, Evalue=7e-20, Organism=Escherichia coli, GI1788761, Length=232, Percent_Identity=26.7241379310345, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI1788225, Length=259, Percent_Identity=27.7992277992278, Blast_Score=89, Evalue=2e-19, Organism=Escherichia coli, GI1786253, Length=227, Percent_Identity=29.9559471365639, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI87081782, Length=217, Percent_Identity=31.3364055299539, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI1787105, Length=244, Percent_Identity=27.8688524590164, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI1786563, Length=219, Percent_Identity=30.5936073059361, Blast_Score=85, Evalue=4e-18, Organism=Escherichia coli, GI1788472, Length=218, Percent_Identity=26.605504587156, Blast_Score=85, Evalue=4e-18, Organism=Escherichia coli, GI87081791, Length=234, Percent_Identity=26.0683760683761, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1790162, Length=244, Percent_Identity=25.4098360655738, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI1788450, Length=237, Percent_Identity=27.8481012658228, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI48994943, Length=216, Percent_Identity=31.9444444444444, Blast_Score=82, Evalue=4e-17, Organism=Escherichia coli, GI1787712, Length=221, Percent_Identity=27.6018099547511, Blast_Score=81, Evalue=5e-17, Organism=Escherichia coli, GI87081709, Length=249, Percent_Identity=25.3012048192771, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1788053, Length=168, Percent_Identity=32.7380952380952, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI1790544, Length=258, Percent_Identity=23.6434108527132, Blast_Score=79, Evalue=4e-16, Organism=Escherichia coli, GI1787370, Length=227, Percent_Identity=26.431718061674, Blast_Score=78, Evalue=7e-16, Organism=Escherichia coli, GI1788644, Length=245, Percent_Identity=28.9795918367347, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1786653, Length=219, Percent_Identity=28.7671232876712, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1790525, Length=237, Percent_Identity=26.1603375527426, Blast_Score=75, Evalue=3e-15, Organism=Escherichia coli, GI48994883, Length=243, Percent_Identity=26.7489711934156, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI1790467, Length=246, Percent_Identity=26.4227642276423, Blast_Score=74, Evalue=9e-15, Organism=Escherichia coli, GI1786398, Length=232, Percent_Identity=26.7241379310345, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1786872, Length=233, Percent_Identity=25.3218884120172, Blast_Score=72, Evalue=2e-14, Organism=Escherichia coli, GI1789586, Length=238, Percent_Identity=27.3109243697479, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1788165, Length=252, Percent_Identity=25.7936507936508, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI1788897, Length=214, Percent_Identity=27.5700934579439, Blast_Score=70, Evalue=9e-14, Organism=Escherichia coli, GI48995001, Length=224, Percent_Identity=25, Blast_Score=68, Evalue=7e-13, Organism=Escherichia coli, GI1788210, Length=209, Percent_Identity=26.3157894736842, Blast_Score=68, Evalue=7e-13, Organism=Escherichia coli, GI87081834, Length=215, Percent_Identity=26.5116279069767, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1790739, Length=229, Percent_Identity=26.2008733624454, Blast_Score=66, Evalue=3e-12, Organism=Escherichia coli, GI1789873, Length=194, Percent_Identity=26.2886597938144, Blast_Score=65, Evalue=4e-12, Organism=Escherichia coli, GI87082267, Length=209, Percent_Identity=27.2727272727273, Blast_Score=64, Evalue=6e-12, Organism=Escherichia coli, GI1787164, Length=211, Percent_Identity=27.4881516587678, Blast_Score=64, Evalue=8e-12, Organism=Escherichia coli, GI1789032, Length=220, Percent_Identity=29.0909090909091, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1787112, Length=234, Percent_Identity=28.6324786324786, Blast_Score=61, Evalue=6e-11, Organism=Escherichia coli, GI1787972, Length=239, Percent_Identity=24.6861924686192, Blast_Score=61, Evalue=8e-11, Organism=Caenorhabditis elegans, GI71983523, Length=207, Percent_Identity=27.536231884058, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI71983516, Length=207, Percent_Identity=27.536231884058, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI71983510, Length=207, Percent_Identity=27.536231884058, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17565586, Length=179, Percent_Identity=30.7262569832402, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17510237, Length=230, Percent_Identity=25.6521739130435, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI115532730, Length=215, Percent_Identity=27.906976744186, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI193208177, Length=237, Percent_Identity=27.4261603375527, Blast_Score=70, Evalue=7e-13, Organism=Caenorhabditis elegans, GI115533608, Length=173, Percent_Identity=28.3236994219653, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17543740, Length=168, Percent_Identity=29.7619047619048, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI193209708, Length=229, Percent_Identity=25.764192139738, Blast_Score=65, Evalue=2e-11, Organism=Caenorhabditis elegans, GI25146777, Length=213, Percent_Identity=27.2300469483568, Blast_Score=64, Evalue=7e-11, Organism=Saccharomyces cerevisiae, GI6324498, Length=204, Percent_Identity=25.9803921568627, Blast_Score=68, Evalue=1e-12, Organism=Saccharomyces cerevisiae, GI6322177, Length=244, Percent_Identity=26.2295081967213, Blast_Score=67, Evalue=3e-12, Organism=Drosophila melanogaster, GI221512771, Length=225, Percent_Identity=26.6666666666667, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI24643674, Length=223, Percent_Identity=25.1121076233184, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI19920532, Length=218, Percent_Identity=27.9816513761468, Blast_Score=73, Evalue=1e-13, Organism=Drosophila melanogaster, GI24580930, Length=218, Percent_Identity=27.9816513761468, Blast_Score=73, Evalue=1e-13, Organism=Drosophila melanogaster, GI24666092, Length=223, Percent_Identity=26.0089686098655, Blast_Score=73, Evalue=1e-13, Organism=Drosophila melanogaster, GI28573573, Length=201, Percent_Identity=27.8606965174129, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI28573571, Length=201, Percent_Identity=27.8606965174129, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI28574150, Length=191, Percent_Identity=29.3193717277487, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI116007328, Length=191, Percent_Identity=29.3193717277487, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI28574533, Length=218, Percent_Identity=25.6880733944954, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24648314, Length=232, Percent_Identity=25.4310344827586, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI24650853, Length=252, Percent_Identity=25.7936507936508, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI24650855, Length=252, Percent_Identity=25.7936507936508, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI24582014, Length=213, Percent_Identity=25.8215962441315, Blast_Score=64, Evalue=9e-11, Organism=Drosophila melanogaster, GI24582012, Length=213, Percent_Identity=25.8215962441315, Blast_Score=64, Evalue=9e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 26622; Mature: 26490
Theoretical pI: Translated: 9.32; Mature: 9.32
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 4.5 %Met (Translated Protein) 4.9 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 4.1 %Met (Mature Protein) 4.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSLILEVKDLHVRYGKVEAVHGANLKVEAGKIVTVIGPNGAGKSTMLNAVMGALPVSGSS CCEEEEEEEEEEECCEEEEECCCCEEEECCCEEEEECCCCCCHHHHHHHHHHHCCCCCCC TGSVRFLGHDMAGIPVEGRVARGMCLVPEKRELFASMTVEDNLLLGAFRRKRAGERNYLD CCEEEEEECCCCCCCCCCHHHCCEEECCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCC QKDVVYDLFPRLRERAKQEAGTLSGGERQMLAVGRALMAKPQLLMLDEPSLGLAPLIVKE HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHH IFHIIHNLRQTGVATLLIEQNARAALQVADYGYVIETGDMAMEGEASALASNPKVIETYL HHHHHHHHHHCCEEEEEEECCCCEEEEEECCCEEEECCCEEECCCCHHHCCCCHHHHHHH GLTKKAA HHHHCCC >Mature Secondary Structure SLILEVKDLHVRYGKVEAVHGANLKVEAGKIVTVIGPNGAGKSTMLNAVMGALPVSGSS CEEEEEEEEEEECCEEEEECCCCEEEECCCEEEEECCCCCCHHHHHHHHHHHCCCCCCC TGSVRFLGHDMAGIPVEGRVARGMCLVPEKRELFASMTVEDNLLLGAFRRKRAGERNYLD CCEEEEEECCCCCCCCCCHHHCCEEECCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCC QKDVVYDLFPRLRERAKQEAGTLSGGERQMLAVGRALMAKPQLLMLDEPSLGLAPLIVKE HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHH IFHIIHNLRQTGVATLLIEQNARAALQVADYGYVIETGDMAMEGEASALASNPKVIETYL HHHHHHHHHHCCEEEEEEECCCCEEEEEECCCEEEECCCEEECCCCHHHCCCCHHHHHHH GLTKKAA HHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; L-leucine [Periplasm]; H2O; ATP; L-valine [Periplasm]; L-iso-leucine [Periplasm] [C]
Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 7.0
TargetDB status: NA
Availability: NA
References: 2120183; 10984043 [H]