Click here to switch to the map view.

The map label for this gene is atpA [H]

Identifier: 94312427

GI number: 94312427

Start: 3787351

End: 3788892

Strand: Reverse

Name: atpA [H]

Synonym: Rmet_3496

Alternate gene names: 94312427

Gene position: 3788892-3787351 (Counterclockwise)

Preceding gene: 94312428

Following gene: 94312426

Centisome position: 96.46

GC content: 62.71

Gene sequence:

>1542_bases
ATGCAACTGAACCCCTCAGAAATCAGCGAGCTGATCAAGTCCCGCATCTCGGGTCTTGGCGCCGACGCTGAAGTGCGCAA
CACCGGCACGGTAATTTCCGTGACCGATGGTATCTGCCGCGTGCACGGCCTGTCTGGCGTGATGCAGGGCGAGATGCTGG
AATTCCCGGGTAACACCTACGGCCTGGCACTGAACCTCGAGCGCGACTCGGTGGGTGCCGTGGTTCTGGGTGAGTACGAA
CACATTTCGGAAGGCGATACGGTCAAGTGCACCGGCCGCATTCTGGAAGTGCCGGTTGGCAAGGAACTGCTGGGCCGCGT
GGTGAACACGCTGGGTCAGCCGATCGACGGCAAGGGCCCGATCAACGCCAAGGAAACGGACGTGATCGAGAAGGTCGCTC
CGGGCGTGATTGCGCGTCAGTCGGTGAGCCAGCCGGTGCAGACCGGTCTGAAGTCGATCGACGCGATGGTGCCGATTGGC
CGTGGCCAGCGTGAGCTGATCATTGGCGACCGCCAGACGGGCAAGACCGCCGTGGCCGTTGACTCGATCATCAACCAGAA
GGGCAAGGGCGTCTTCTGCGTGTACGTGGCAATCGGCCAGAAGGCTTCGACGATCTCCAACGTGGTGCGCAAGCTGGAAG
AGCACGGCGCCATGGAGTACACGATCGTCGTGGCCGCAACGGCTTCGGACTCGGCCGCCATGCAGTACCTGGCTGCCTAC
GCCGGCTGCACGATGGGCGAATACTTCCGCGACCGCGGTGAAGACGCGCTGATCGTTTATGACGATCTGACCAAGCAGGC
CTGGGCCTACCGTCAGGTGTCGCTGCTGCTGCGCCGCCCGCCGGGCCGCGAAGCCTACCCTGGCGACGTGTTCTACCTGC
ACTCGCGTCTGCTCGAGCGCGCTGCCCGCGTGAACGAAGACTACGTGGCCAAGTTCACGAACGGCGCCGTTACCGGCAAG
ACCGGTTCGCTGACCGCGCTGCCCGTGATCGAAACGCAGGCCGGTGACGTGTCCGCATTCGTGCCGACCAACGTGATCTC
GATTACCGACGGTCAGATCTTCCTGGAAACCGACCTGTTCAACGCCGGTATCCGCCCCGCTATCAACGCCGGTATTTCGG
TGTCGCGTGTGGGTGGTGCAGCGCAGACCAAGGTCATCAAGAAGCTCTCCGGTGGTATCCGTACCGACCTGGCCCAGTAC
CGTGAACTGGCTGCGTTCGCGCAGTTTGCTTCGGACCTGGACGACGCTACCCGCAAGCAGCTCGAGCGCGGCCGCCGCGT
GACCGAACTGCTCAAGCAGCCGCAATACCAGCCGCTGCAGGTGTGGCAACTCGCCGCGTCGCTGTATGCCGCCAACAACG
GCTTCCTCGACAACGTCGACGTGAAGGACATTCTGCCGTTCGAGAAGGGCCTGCACGACCACCTGAAGACCAAGTTCGCC
GACCTCGTCAACCGCATCGAAGATACCAAGGATCTGTCGAAGGAAGACGAAGCCGCCCTGCGTGCAGCGATCGAGGATTT
CAGGAAGTCCGCCGCGTTCTAA

Upstream 100 bases:

>100_bases
AGTGCTCGACACCTCCGTGCGCTCGCGTCTGGCTGCCATGCAAGCCGCGCTGACCGCCTGACCGCAACGGCCGACGGATT
GAAGAATTAGGAGCATTGTG

Downstream 100 bases:

>100_bases
CCGCGTGATTCCATGTGTTGCGCCGGGCGCGCCGTAAGGCGCGCGGCGCGGCACGAGTGGAGAGGAAGATATGGCCGGAA
CGAAAGAGATTCGAACCAAG

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MQLNPSEISELIKSRISGLGADAEVRNTGTVISVTDGICRVHGLSGVMQGEMLEFPGNTYGLALNLERDSVGAVVLGEYE
HISEGDTVKCTGRILEVPVGKELLGRVVNTLGQPIDGKGPINAKETDVIEKVAPGVIARQSVSQPVQTGLKSIDAMVPIG
RGQRELIIGDRQTGKTAVAVDSIINQKGKGVFCVYVAIGQKASTISNVVRKLEEHGAMEYTIVVAATASDSAAMQYLAAY
AGCTMGEYFRDRGEDALIVYDDLTKQAWAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARVNEDYVAKFTNGAVTGK
TGSLTALPVIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGIRPAINAGISVSRVGGAAQTKVIKKLSGGIRTDLAQY
RELAAFAQFASDLDDATRKQLERGRRVTELLKQPQYQPLQVWQLAASLYAANNGFLDNVDVKDILPFEKGLHDHLKTKFA
DLVNRIEDTKDLSKEDEAALRAAIEDFRKSAAF

Sequences:

>Translated_513_residues
MQLNPSEISELIKSRISGLGADAEVRNTGTVISVTDGICRVHGLSGVMQGEMLEFPGNTYGLALNLERDSVGAVVLGEYE
HISEGDTVKCTGRILEVPVGKELLGRVVNTLGQPIDGKGPINAKETDVIEKVAPGVIARQSVSQPVQTGLKSIDAMVPIG
RGQRELIIGDRQTGKTAVAVDSIINQKGKGVFCVYVAIGQKASTISNVVRKLEEHGAMEYTIVVAATASDSAAMQYLAAY
AGCTMGEYFRDRGEDALIVYDDLTKQAWAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARVNEDYVAKFTNGAVTGK
TGSLTALPVIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGIRPAINAGISVSRVGGAAQTKVIKKLSGGIRTDLAQY
RELAAFAQFASDLDDATRKQLERGRRVTELLKQPQYQPLQVWQLAASLYAANNGFLDNVDVKDILPFEKGLHDHLKTKFA
DLVNRIEDTKDLSKEDEAALRAAIEDFRKSAAF
>Mature_513_residues
MQLNPSEISELIKSRISGLGADAEVRNTGTVISVTDGICRVHGLSGVMQGEMLEFPGNTYGLALNLERDSVGAVVLGEYE
HISEGDTVKCTGRILEVPVGKELLGRVVNTLGQPIDGKGPINAKETDVIEKVAPGVIARQSVSQPVQTGLKSIDAMVPIG
RGQRELIIGDRQTGKTAVAVDSIINQKGKGVFCVYVAIGQKASTISNVVRKLEEHGAMEYTIVVAATASDSAAMQYLAAY
AGCTMGEYFRDRGEDALIVYDDLTKQAWAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARVNEDYVAKFTNGAVTGK
TGSLTALPVIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGIRPAINAGISVSRVGGAAQTKVIKKLSGGIRTDLAQY
RELAAFAQFASDLDDATRKQLERGRRVTELLKQPQYQPLQVWQLAASLYAANNGFLDNVDVKDILPFEKGLHDHLKTKFA
DLVNRIEDTKDLSKEDEAALRAAIEDFRKSAAF

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=510, Percent_Identity=57.0588235294118, Blast_Score=586, Evalue=1e-167,
Organism=Homo sapiens, GI4757810, Length=510, Percent_Identity=57.0588235294118, Blast_Score=586, Evalue=1e-167,
Organism=Homo sapiens, GI32189394, Length=498, Percent_Identity=25.3012048192771, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI19913428, Length=312, Percent_Identity=28.2051282051282, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI19913426, Length=312, Percent_Identity=28.525641025641, Blast_Score=109, Evalue=8e-24,
Organism=Homo sapiens, GI19913424, Length=262, Percent_Identity=27.4809160305344, Blast_Score=76, Evalue=6e-14,
Organism=Escherichia coli, GI1790172, Length=513, Percent_Identity=69.7855750487329, Blast_Score=741, Evalue=0.0,
Organism=Escherichia coli, GI1790170, Length=493, Percent_Identity=24.9492900608519, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1788251, Length=281, Percent_Identity=27.7580071174377, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71988063, Length=510, Percent_Identity=56.6666666666667, Blast_Score=579, Evalue=1e-166,
Organism=Caenorhabditis elegans, GI71988080, Length=510, Percent_Identity=56.6666666666667, Blast_Score=578, Evalue=1e-165,
Organism=Caenorhabditis elegans, GI71988074, Length=510, Percent_Identity=52.7450980392157, Blast_Score=528, Evalue=1e-150,
Organism=Caenorhabditis elegans, GI25144756, Length=436, Percent_Identity=24.3119266055046, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17570191, Length=303, Percent_Identity=28.3828382838284, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17510931, Length=383, Percent_Identity=26.3707571801567, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=60, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17565854, Length=254, Percent_Identity=27.5590551181102, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319370, Length=512, Percent_Identity=56.25, Blast_Score=577, Evalue=1e-165,
Organism=Saccharomyces cerevisiae, GI6322581, Length=424, Percent_Identity=26.4150943396226, Blast_Score=130, Evalue=7e-31,
Organism=Saccharomyces cerevisiae, GI6319603, Length=309, Percent_Identity=29.126213592233, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24658560, Length=510, Percent_Identity=57.843137254902, Blast_Score=585, Evalue=1e-167,
Organism=Drosophila melanogaster, GI281361666, Length=305, Percent_Identity=28.5245901639344, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24646341, Length=305, Percent_Identity=28.5245901639344, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI17136796, Length=305, Percent_Identity=28.5245901639344, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24638766, Length=458, Percent_Identity=25.1091703056769, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI28574560, Length=385, Percent_Identity=24.4155844155844, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24583988, Length=255, Percent_Identity=27.4509803921569, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24583986, Length=255, Percent_Identity=27.4509803921569, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24583984, Length=255, Percent_Identity=27.4509803921569, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24583992, Length=255, Percent_Identity=27.4509803921569, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI20129479, Length=248, Percent_Identity=27.8225806451613, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55474; Mature: 55474

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLNPSEISELIKSRISGLGADAEVRNTGTVISVTDGICRVHGLSGVMQGEMLEFPGNTY
CCCCHHHHHHHHHHHHHCCCCCCEECCCCCEEEECCCHHHHHCCCHHHCCCEEECCCCEE
GLALNLERDSVGAVVLGEYEHISEGDTVKCTGRILEVPVGKELLGRVVNTLGQPIDGKGP
EEEEEECCCCCCEEEEECCHHCCCCCEEEEECEEEECCCCHHHHHHHHHHHCCCCCCCCC
INAKETDVIEKVAPGVIARQSVSQPVQTGLKSIDAMVPIGRGQRELIIGDRQTGKTAVAV
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHH
DSIINQKGKGVFCVYVAIGQKASTISNVVRKLEEHGAMEYTIVVAATASDSAAMQYLAAY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHH
AGCTMGEYFRDRGEDALIVYDDLTKQAWAYRQVSLLLRRPPGREAYPGDVFYLHSRLLER
HCCHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVNEDYVAKFTNGAVTGKTGSLTALPVIETQAGDVSAFVPTNVISITDGQIFLETDLF
HHHCCHHHHHHCCCCEEECCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECHH
NAGIRPAINAGISVSRVGGAAQTKVIKKLSGGIRTDLAQYRELAAFAQFASDLDDATRKQ
CCCCCHHHHCCCEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LERGRRVTELLKQPQYQPLQVWQLAASLYAANNGFLDNVDVKDILPFEKGLHDHLKTKFA
HHHCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHHHH
DLVNRIEDTKDLSKEDEAALRAAIEDFRKSAAF
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQLNPSEISELIKSRISGLGADAEVRNTGTVISVTDGICRVHGLSGVMQGEMLEFPGNTY
CCCCHHHHHHHHHHHHHCCCCCCEECCCCCEEEECCCHHHHHCCCHHHCCCEEECCCCEE
GLALNLERDSVGAVVLGEYEHISEGDTVKCTGRILEVPVGKELLGRVVNTLGQPIDGKGP
EEEEEECCCCCCEEEEECCHHCCCCCEEEEECEEEECCCCHHHHHHHHHHHCCCCCCCCC
INAKETDVIEKVAPGVIARQSVSQPVQTGLKSIDAMVPIGRGQRELIIGDRQTGKTAVAV
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHH
DSIINQKGKGVFCVYVAIGQKASTISNVVRKLEEHGAMEYTIVVAATASDSAAMQYLAAY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHH
AGCTMGEYFRDRGEDALIVYDDLTKQAWAYRQVSLLLRRPPGREAYPGDVFYLHSRLLER
HCCHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVNEDYVAKFTNGAVTGKTGSLTALPVIETQAGDVSAFVPTNVISITDGQIFLETDLF
HHHCCHHHHHHCCCCEEECCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECHH
NAGIRPAINAGISVSRVGGAAQTKVIKKLSGGIRTDLAQYRELAAFAQFASDLDDATRKQ
CCCCCHHHHCCCEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LERGRRVTELLKQPQYQPLQVWQLAASLYAANNGFLDNVDVKDILPFEKGLHDHLKTKFA
HHHCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHHHH
DLVNRIEDTKDLSKEDEAALRAAIEDFRKSAAF
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA