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The map label for this gene is ompR [H]

Identifier: 94312408

GI number: 94312408

Start: 3757485

End: 3758270

Strand: Reverse

Name: ompR [H]

Synonym: Rmet_3477

Alternate gene names: 94312408

Gene position: 3758270-3757485 (Counterclockwise)

Preceding gene: 94312409

Following gene: 94312407

Centisome position: 95.68

GC content: 66.03

Gene sequence:

>786_bases
TTGGGTGCTCCATCCGGCCGCGGTTCCGCGGCCGTTCCCATCCGCAAGCTCGCCATGGACCTGTCCCCCGCTCTGCCAAT
CCGCCTGCTGATCGTCGACGACGACCCACAAATCCGGGCCATGCTGGCCGAATACCTCGCCACATTCGGCATGGAGGCCG
AAGGTGCCGAAGGCGGCACTGCCATGCGTGCGGCGATGTCGAAGCAGGAATACGACCTCGTCATCCTGGATCTCTCGCTG
CCCGGCGAGAACGGCCTGACGTTGTGCCGCGAAATCCGGGAGTCCAGCAACCTGCCTGTGATCATGCTGACCGCCCGCGC
GGAACTGGCCGATCGCGTGGTGGGACTCGAGGTGGGCGCGGACGACTACGTGACCAAGCCGTTCGAGATGCGCGAGCTGG
TGGCGCGCATCCATACCGTGCTGCGTCGCAGCCGTGCCGACGTGCGACGTCCGGCGCCGGCTGCGCCCGGGCATGAAGTC
CGGTTCGCGGCATGGCGACTGAACACCACGCTGCGCCAGCTGGTGGATGCCGAGGACACGGTGGTGCCGCTTTCCAACGC
GGAATTCCGGCTGCTGCTGACATTCATCGAGCATCCCAATCGCGTGCTCGATCGCGAGATGCTGATCAACACCGCGCGTG
GACGCGATCTGGACGTGTTCGATCGCAGCATCGACCTGCTGGTGTCCCGTCTGCGCCAGAAGCTGCGTGACGATCCGCGC
GACTCGGCACTGATCCGCACCGTGCGTGGCGAAGGGTACGTCTTCACGGGCACCGTGGAGCACTGA

Upstream 100 bases:

>100_bases
CCGGGGGCGTTTTTTTCCGCCTCTCGCTACTTGTGGCGTTTTGCGCACGTATCAAGTTTGATACAAAACCGGCATCGCTT
GTAATGGGCAAGCTGGTACA

Downstream 100 bases:

>100_bases
CGGCATGGCCGCGCAGATGCCGCCATCGGCGGACGATCCACCGATCGTGCGGCCCGAATTGCGTTCCAGCGCATCGGAGA
CGCCCCGAAGGCGCTTCGAT

Product: DNA-binding response regulator in two-component regulatory system with EnvZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MGAPSGRGSAAVPIRKLAMDLSPALPIRLLIVDDDPQIRAMLAEYLATFGMEAEGAEGGTAMRAAMSKQEYDLVILDLSL
PGENGLTLCREIRESSNLPVIMLTARAELADRVVGLEVGADDYVTKPFEMRELVARIHTVLRRSRADVRRPAPAAPGHEV
RFAAWRLNTTLRQLVDAEDTVVPLSNAEFRLLLTFIEHPNRVLDREMLINTARGRDLDVFDRSIDLLVSRLRQKLRDDPR
DSALIRTVRGEGYVFTGTVEH

Sequences:

>Translated_261_residues
MGAPSGRGSAAVPIRKLAMDLSPALPIRLLIVDDDPQIRAMLAEYLATFGMEAEGAEGGTAMRAAMSKQEYDLVILDLSL
PGENGLTLCREIRESSNLPVIMLTARAELADRVVGLEVGADDYVTKPFEMRELVARIHTVLRRSRADVRRPAPAAPGHEV
RFAAWRLNTTLRQLVDAEDTVVPLSNAEFRLLLTFIEHPNRVLDREMLINTARGRDLDVFDRSIDLLVSRLRQKLRDDPR
DSALIRTVRGEGYVFTGTVEH
>Mature_260_residues
GAPSGRGSAAVPIRKLAMDLSPALPIRLLIVDDDPQIRAMLAEYLATFGMEAEGAEGGTAMRAAMSKQEYDLVILDLSLP
GENGLTLCREIRESSNLPVIMLTARAELADRVVGLEVGADDYVTKPFEMRELVARIHTVLRRSRADVRRPAPAAPGHEVR
FAAWRLNTTLRQLVDAEDTVVPLSNAEFRLLLTFIEHPNRVLDREMLINTARGRDLDVFDRSIDLLVSRLRQKLRDDPRD
SALIRTVRGEGYVFTGTVEH

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=233, Percent_Identity=42.9184549356223, Blast_Score=193, Evalue=8e-51,
Organism=Escherichia coli, GI1787229, Length=237, Percent_Identity=38.8185654008439, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1790863, Length=238, Percent_Identity=35.2941176470588, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1788394, Length=231, Percent_Identity=38.961038961039, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=37.5, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=37.8260869565217, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=35.9649122807018, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=30.3030303030303, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=35.4978354978355, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786911, Length=230, Percent_Identity=36.5217391304348, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI87082012, Length=229, Percent_Identity=29.6943231441048, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1789402, Length=230, Percent_Identity=33.9130434782609, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787375, Length=235, Percent_Identity=31.4893617021277, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1790552, Length=236, Percent_Identity=32.2033898305085, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1790299, Length=110, Percent_Identity=35.4545454545455, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=37.3831775700935, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1788713, Length=118, Percent_Identity=33.8983050847458, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI145693157, Length=100, Percent_Identity=35, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 29037; Mature: 28906

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAPSGRGSAAVPIRKLAMDLSPALPIRLLIVDDDPQIRAMLAEYLATFGMEAEGAEGGT
CCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCH
AMRAAMSKQEYDLVILDLSLPGENGLTLCREIRESSNLPVIMLTARAELADRVVGLEVGA
HHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCEEEEECCHHHHHHHEEEEECC
DDYVTKPFEMRELVARIHTVLRRSRADVRRPAPAAPGHEVRFAAWRLNTTLRQLVDAEDT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEHHHHHHHHHCCCCC
VVPLSNAEFRLLLTFIEHPNRVLDREMLINTARGRDLDVFDRSIDLLVSRLRQKLRDDPR
EEECCCCCCEEEHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
DSALIRTVRGEGYVFTGTVEH
CCHHEEEECCCCEEEEEEECC
>Mature Secondary Structure 
GAPSGRGSAAVPIRKLAMDLSPALPIRLLIVDDDPQIRAMLAEYLATFGMEAEGAEGGT
CCCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCH
AMRAAMSKQEYDLVILDLSLPGENGLTLCREIRESSNLPVIMLTARAELADRVVGLEVGA
HHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCEEEEECCHHHHHHHEEEEECC
DDYVTKPFEMRELVARIHTVLRRSRADVRRPAPAAPGHEVRFAAWRLNTTLRQLVDAEDT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEHHHHHHHHHCCCCC
VVPLSNAEFRLLLTFIEHPNRVLDREMLINTARGRDLDVFDRSIDLLVSRLRQKLRDDPR
EEECCCCCCEEEHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
DSALIRTVRGEGYVFTGTVEH
CCHHEEEECCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]