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The map label for this gene is ftsI [H]

Identifier: 94312065

GI number: 94312065

Start: 3398602

End: 3400419

Strand: Reverse

Name: ftsI [H]

Synonym: Rmet_3134

Alternate gene names: 94312065

Gene position: 3400419-3398602 (Counterclockwise)

Preceding gene: 94312066

Following gene: 94312064

Centisome position: 86.57

GC content: 66.28

Gene sequence:

>1818_bases
ATGAGCATGGCCCGGCCAACCATGAACCGCGCCCGCGCCGGCAACAAGTCGCGCGGCGAGGCAGCCCGTCCGCGCACCGG
CCAGTTCTCCGCCAGCCCGGTGCTGGGTCTGCGCCTGCCGATGTGGCGCTCGAAGTTCGTGGTGTTCCTGATGTTCGCCG
CGTTCCTGGCGCTGGCCGCGCGCGCGATGTGGATTCAGGGCCCGGGCAACCAGTTCTACGAGATGGAGGGCAAGAAGCGC
TTCCAGCGCACGCTGGAGCTGCCCGCCACGCGCGGCAAGATCCTGGATCGCAACGGCCTGGTGCTGGCCACCAGCCTGCC
GGTCAAGGCGATCTGGGCCGTGCCCGAGGACGTGCCGAACGATCTCGATCCGCAGCGCATGCGCCAATTGGCCAAGCTGC
TGGACATGTCCGAAAAGGAACTGCGCGCCAAGTTCAACGAGGACAAGAGCTTCGTCTACCTGAAGCGCCAGGTGCTGCCC
GATGCGGCCGACAAGATCGCCGCGCTCAAGATCGATGGCGTTCACCAGACTCGCGAATACAAGCGCTTCTATCCCGAAGG
CGAGGCGATGGCGCATATCGTCGGCTTCACCAACGTCGAGGACAAGGGGCAGGAAGGTGTGGAACTGGCGCGTGAAAGCG
TGCTGGCAGGCCGTCCCGGCGCGCGTCAGGTGATCAAGGATCGCCTGGGCCGCGTGGTGGAAGACGTCGGCATCCTGAAG
ACCCCGCGCGACGGCGAGGACATGCAGCTGTCGATCGACGCCAAGATCCAGTACCTGGCCTACAACGAGGTCAAGGCCGT
GGTCGAGCGTAGCAAGGCAAAGGCCGCCAGCGCCGTGGTGCTCGATGCGCAGACCGGCGAGGTGCTGGCGCTGGCCAACT
GGCCGACCTACAACCCGAACGACCGCAGCCGCCTGTCGGGCGAGCAGCTTCGCAACCGCGTGCTGACCGATACCTTCGAG
CCCGGCTCGATGATGAAGCCGATTTCGATCGGGCTGGCGCTGCAGCTTGGCCGCGTGACGCCGTCGACGACCATCGTGAC
GACCGGCAAGTTCAACTTCGAAGGCGCGACGATCTCCGATACCCACAACTACGGCACGCTCACGGTGGGCGGTGTGATCC
AGAAGTCGAGCAACATCGGCACGACGAAGATCGCGATGATGATGAAGCCGCAGGAGATGTGGGACATGTTTACCAGCGTC
GGCCTGGGCCAGGCGCCGAAGATCGGCTTCCCGGGTGCCGTGGCGGGTCGCGTGCGGCCGTGGAAGAGCTGGCGGCCGAT
CGAGCAGGCGACGATGTCCTATGGCTATGGCCTCTCGGTGTCGCTGTTCCAGATCGCGCACGCCTATACGATCTTCGCGC
ACGATGGCGAGCTGATTCCCGTGTCGATCTTCAAGACCAACGGCCCGACAGACGGCGAACGCATCCTGTCGCCCCAGGTT
GCCCGCCAGGTGCGCGGCATGCTCGAAACCGTGACAGCGCCCGGCGGTACCGCGCCCGAGGCCCAGGTGATGGGCTACCG
CGTCGGCGGCAAGACCGGCACTGCATACAAGCACGTAGGCCGCGGCTACGACCGCAGCAAGTACCGCGCCTCGTTCATCG
GCCTGGCCCCGATGTCGAACCCGCGCGTGATCGTGGCCGTCAGCGTGGACGAGCCGACCTCCGGCAGCCACTACGGTGGC
GCGGTCGCCGGCCCGGTCTTCTCGGCCATCACCGGCGGCGCTCTGCGCGCGCTGAATGTCCAGCCCGACTCGCCGATCCG
GCAGTTGATGGTCACCGACAAGGTGCCTGAGAGCGAACCATGGAGCGCGACCCAATGA

Upstream 100 bases:

>100_bases
AGATGTCGCCGGCGGTGGCCGGTCGTACCCAGTATCTGCAAGGCGTGGTGCTGCCATCGACGCCGCCGGATGCCGAACAA
CCCGCAGAGGGGGCAGCCAA

Downstream 100 bases:

>100_bases
CGCGCCAGCCGCTGCTTCCGCTCGAAGTCTCCGCCCAGGCCAGCAACGCGCTGGCCTGGCTGCGTACGCACGCCCCGGAA
AACGCGCAGTTGACCGGCGA

Product: penicillin-binding protein 3

Products: NA

Alternate protein names: PBP-2 [H]

Number of amino acids: Translated: 605; Mature: 604

Protein sequence:

>605_residues
MSMARPTMNRARAGNKSRGEAARPRTGQFSASPVLGLRLPMWRSKFVVFLMFAAFLALAARAMWIQGPGNQFYEMEGKKR
FQRTLELPATRGKILDRNGLVLATSLPVKAIWAVPEDVPNDLDPQRMRQLAKLLDMSEKELRAKFNEDKSFVYLKRQVLP
DAADKIAALKIDGVHQTREYKRFYPEGEAMAHIVGFTNVEDKGQEGVELARESVLAGRPGARQVIKDRLGRVVEDVGILK
TPRDGEDMQLSIDAKIQYLAYNEVKAVVERSKAKAASAVVLDAQTGEVLALANWPTYNPNDRSRLSGEQLRNRVLTDTFE
PGSMMKPISIGLALQLGRVTPSTTIVTTGKFNFEGATISDTHNYGTLTVGGVIQKSSNIGTTKIAMMMKPQEMWDMFTSV
GLGQAPKIGFPGAVAGRVRPWKSWRPIEQATMSYGYGLSVSLFQIAHAYTIFAHDGELIPVSIFKTNGPTDGERILSPQV
ARQVRGMLETVTAPGGTAPEAQVMGYRVGGKTGTAYKHVGRGYDRSKYRASFIGLAPMSNPRVIVAVSVDEPTSGSHYGG
AVAGPVFSAITGGALRALNVQPDSPIRQLMVTDKVPESEPWSATQ

Sequences:

>Translated_605_residues
MSMARPTMNRARAGNKSRGEAARPRTGQFSASPVLGLRLPMWRSKFVVFLMFAAFLALAARAMWIQGPGNQFYEMEGKKR
FQRTLELPATRGKILDRNGLVLATSLPVKAIWAVPEDVPNDLDPQRMRQLAKLLDMSEKELRAKFNEDKSFVYLKRQVLP
DAADKIAALKIDGVHQTREYKRFYPEGEAMAHIVGFTNVEDKGQEGVELARESVLAGRPGARQVIKDRLGRVVEDVGILK
TPRDGEDMQLSIDAKIQYLAYNEVKAVVERSKAKAASAVVLDAQTGEVLALANWPTYNPNDRSRLSGEQLRNRVLTDTFE
PGSMMKPISIGLALQLGRVTPSTTIVTTGKFNFEGATISDTHNYGTLTVGGVIQKSSNIGTTKIAMMMKPQEMWDMFTSV
GLGQAPKIGFPGAVAGRVRPWKSWRPIEQATMSYGYGLSVSLFQIAHAYTIFAHDGELIPVSIFKTNGPTDGERILSPQV
ARQVRGMLETVTAPGGTAPEAQVMGYRVGGKTGTAYKHVGRGYDRSKYRASFIGLAPMSNPRVIVAVSVDEPTSGSHYGG
AVAGPVFSAITGGALRALNVQPDSPIRQLMVTDKVPESEPWSATQ
>Mature_604_residues
SMARPTMNRARAGNKSRGEAARPRTGQFSASPVLGLRLPMWRSKFVVFLMFAAFLALAARAMWIQGPGNQFYEMEGKKRF
QRTLELPATRGKILDRNGLVLATSLPVKAIWAVPEDVPNDLDPQRMRQLAKLLDMSEKELRAKFNEDKSFVYLKRQVLPD
AADKIAALKIDGVHQTREYKRFYPEGEAMAHIVGFTNVEDKGQEGVELARESVLAGRPGARQVIKDRLGRVVEDVGILKT
PRDGEDMQLSIDAKIQYLAYNEVKAVVERSKAKAASAVVLDAQTGEVLALANWPTYNPNDRSRLSGEQLRNRVLTDTFEP
GSMMKPISIGLALQLGRVTPSTTIVTTGKFNFEGATISDTHNYGTLTVGGVIQKSSNIGTTKIAMMMKPQEMWDMFTSVG
LGQAPKIGFPGAVAGRVRPWKSWRPIEQATMSYGYGLSVSLFQIAHAYTIFAHDGELIPVSIFKTNGPTDGERILSPQVA
RQVRGMLETVTAPGGTAPEAQVMGYRVGGKTGTAYKHVGRGYDRSKYRASFIGLAPMSNPRVIVAVSVDEPTSGSHYGGA
VAGPVFSAITGGALRALNVQPDSPIRQLMVTDKVPESEPWSATQ

Specific function: Synthesis of cross-linked peptidoglycan from the lipid intermediates [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=548, Percent_Identity=41.4233576642336, Blast_Score=416, Evalue=1e-117,
Organism=Escherichia coli, GI1786854, Length=566, Percent_Identity=23.6749116607774, Blast_Score=105, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005311
- InterPro:   IPR001460 [H]

Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 66117; Mature: 65986

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMARPTMNRARAGNKSRGEAARPRTGQFSASPVLGLRLPMWRSKFVVFLMFAAFLALAA
CCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHH
RAMWIQGPGNQFYEMEGKKRFQRTLELPATRGKILDRNGLVLATSLPVKAIWAVPEDVPN
HEEEEECCCCCEEECCHHHHHHHHHCCCCCCCCEECCCCEEEEECCCEEEEEECCCCCCC
DLDPQRMRQLAKLLDMSEKELRAKFNEDKSFVYLKRQVLPDAADKIAALKIDGVHQTREY
CCCHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEEEHHHCCCCHHCEEEEEECCCHHHHHH
KRFYPEGEAMAHIVGFTNVEDKGQEGVELARESVLAGRPGARQVIKDRLGRVVEDVGILK
HHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC
TPRDGEDMQLSIDAKIQYLAYNEVKAVVERSKAKAASAVVLDAQTGEVLALANWPTYNPN
CCCCCCCEEEEEECEEEEEEHHHHHHHHHHHHHHHCEEEEEECCCCCEEEEECCCCCCCC
DRSRLSGEQLRNRVLTDTFEPGSMMKPISIGLALQLGRVTPSTTIVTTGKFNFEGATISD
CHHHCCHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCCCEEEEECEEEECCCEEEC
THNYGTLTVGGVIQKSSNIGTTKIAMMMKPQEMWDMFTSVGLGQAPKIGFPGAVAGRVRP
CCCCCEEEECCEEECCCCCCCEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
WKSWRPIEQATMSYGYGLSVSLFQIAHAYTIFAHDGELIPVSIFKTNGPTDGERILSPQV
CCCCCCHHHHHHHCCCCCCHHHHHHEEEEEEEEECCCEEEEEEEECCCCCCCHHHCCHHH
ARQVRGMLETVTAPGGTAPEAQVMGYRVGGKTGTAYKHVGRGYDRSKYRASFIGLAPMSN
HHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCCCCHHEEEEEEECCCCC
PRVIVAVSVDEPTSGSHYGGAVAGPVFSAITGGALRALNVQPDSPIRQLMVTDKVPESEP
CCEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCCCC
WSATQ
CCCCC
>Mature Secondary Structure 
SMARPTMNRARAGNKSRGEAARPRTGQFSASPVLGLRLPMWRSKFVVFLMFAAFLALAA
CCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHH
RAMWIQGPGNQFYEMEGKKRFQRTLELPATRGKILDRNGLVLATSLPVKAIWAVPEDVPN
HEEEEECCCCCEEECCHHHHHHHHHCCCCCCCCEECCCCEEEEECCCEEEEEECCCCCCC
DLDPQRMRQLAKLLDMSEKELRAKFNEDKSFVYLKRQVLPDAADKIAALKIDGVHQTREY
CCCHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEEEHHHCCCCHHCEEEEEECCCHHHHHH
KRFYPEGEAMAHIVGFTNVEDKGQEGVELARESVLAGRPGARQVIKDRLGRVVEDVGILK
HHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC
TPRDGEDMQLSIDAKIQYLAYNEVKAVVERSKAKAASAVVLDAQTGEVLALANWPTYNPN
CCCCCCCEEEEEECEEEEEEHHHHHHHHHHHHHHHCEEEEEECCCCCEEEEECCCCCCCC
DRSRLSGEQLRNRVLTDTFEPGSMMKPISIGLALQLGRVTPSTTIVTTGKFNFEGATISD
CHHHCCHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCCCEEEEECEEEECCCEEEC
THNYGTLTVGGVIQKSSNIGTTKIAMMMKPQEMWDMFTSVGLGQAPKIGFPGAVAGRVRP
CCCCCEEEECCEEECCCCCCCEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
WKSWRPIEQATMSYGYGLSVSLFQIAHAYTIFAHDGELIPVSIFKTNGPTDGERILSPQV
CCCCCCHHHHHHHCCCCCCHHHHHHEEEEEEEEECCCEEEEEEEECCCCCCCHHHCCHHH
ARQVRGMLETVTAPGGTAPEAQVMGYRVGGKTGTAYKHVGRGYDRSKYRASFIGLAPMSN
HHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCCCCHHEEEEEEECCCCC
PRVIVAVSVDEPTSGSHYGGAVAGPVFSAITGGALRALNVQPDSPIRQLMVTDKVPESEP
CCEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCCCC
WSATQ
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3126399 [H]